carmustine has been researched along with Acute Myelogenous Leukemia in 36 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Between March 1993 and June 2002, we treated 33 relapsed acute myelogenous leukemia (AML) patients with busulfan-based preparative regimens and selective TCD." | 5.11 | CD8+ T-cell-depleted, matched unrelated donor, allogeneic bone marrow transplantation for advanced AML using busulfan-based preparative regimens. ( Andresen, S; Ball, E; Bolwell, B; Cook, D; Kalaycio, M; Kuczkowski, E; Pohlman, B; Rybicki, L; Sobecks, R, 2005) |
| " Graft-versus-host disease prophylaxis consisted of cyclosporine A and alemtuzumab (10-20 mg)." | 3.78 | Radiation-free allogeneic conditioning with fludarabine, carmustine, and thiotepa for acute lymphoblastic leukemia and other hematologic malignancies necessitating enhanced central nervous system activity. ( Bertz, H; Christopoulos, P; Finke, J; Ihorst, G; Marks, R; Wäsch, R, 2012) |
| "Of 209 Hodgkin's disease patients treated at least 6 months with a five-drug combination of induction chemotherapy and having a complete remission, four patients developed acute myelogenous leukemia (AML) as a second malignant neoplasm." | 2.65 | Acute myelogenous leukemia as a second malignant neoplasm following the successful treatment of advanced Hodgkin's disease. ( Bartolucci, AA; Durant, JR; Gams, RA; Liu, C, 1983) |
| "Etoposide has also been tested in a wide range of combination regimens, but for many of these combinations, relatively few patients are included, and some combinations have only been tested in patients who have undergone autologous transplants." | 2.48 | High-dose etoposide in allogeneic stem cell transplantation. ( Ahmed, AB; Bruserud, O; Hatfield, KJ; Kittang, AO; Reikvam, H; Sjo, M; Tvedt, TH, 2012) |
| " Alternative dosing regimens, such as 1-week on/1-week off, or 3-week on/1-week off, that deliver more prolonged exposure have been observed to result in higher cumulative doses than the standard 5-day regimen and may deplete tumor-derived O6-methylguanine-DNA methyltransferase (MGMT) in tumor cells, thus sensitizing tumor cells to the effects of TMZ." | 2.45 | [Treatment of glioma with temozolomide]. ( Nishikawa, R, 2009) |
| "Cytogenetic analysis showed complex chromosomal abnormalities including 11q23 rearrangement, which is frequently found in topoisomerase II inhibitor-related hematologic malignancies." | 1.31 | A case of treatment-related myelodysplastic syndrome and acute myelogenous leukemia following high-dose chemotherapy with autologous stem cell transplantation for non-Hodgkin's lymphoma. ( Bahng, HS; Jang, GD; Jeong, YH; Ji, HS; Kim, EK; Kim, SH; Kim, SW; Kim, WK; Lee, JS; Park, CJ; Park, IG; Suh, CW; Suh, EJ, 2002) |
| "Eleven patients with acute myeloblastic leukemia (AML) beyond the first complete remission or chronic myelogenous leukemia (CML) not in first chronic phase received an association of 13." | 1.29 | Total body irradiation and high-dose cyclophosphamide, BCNU and VP-16 (CBV) as a new preparatory regimen for allogeneic bone marrow transplantation in patients with advanced hematologic malignancies. ( Bourdin, S; Harousseau, JL; Le Tortorec, S; Mahe, B; Mahe, JM; Mechinaud-Lacroix, F; Milpied, N; Moreau, P; Rapp, MJ; Wu, DP, 1994) |
| "Twenty-one acute myelogenous leukemia (AML) patients were submitted in second remission (II CR) to BAVC conditioning regimen followed by unpurged ABMT." | 1.28 | BAVC regimen and autologous bone marrow transplantation in patients with acute myelogenous leukemia in second remission. ( De Fabritiis, P; Mandelli, F; Meloni, G; Petti, MC, 1990) |
| "Seven patients with metastatic tumors resistant to therapy with adriamycin, BCNU, plus cyclophosphamide received the same chemotherapy combined with amphotericin B." | 1.26 | Amphotericin B induction of sensitivity to adriamycin, 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU) plus cyclophosphamide in human neoplasia. ( Klahr, C; Presant, CA; Santala, R, 1977) |
| "Chronic granulocytic leukemia (CGL) terminates in a disease similar to acute leukemia." | 1.26 | Blast crisis of chronic granulocytic leukemia. Morphologic variants and therapeutic implications. ( Canellos, GP; Gralnick, HR; Rosenthal, S; Whang-Peng, J, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (52.78) | 18.7374 |
| 1990's | 8 (22.22) | 18.2507 |
| 2000's | 6 (16.67) | 29.6817 |
| 2010's | 3 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wais, V | 1 |
| Kündgen, L | 1 |
| Bohl, SR | 1 |
| von Harsdorf, S | 1 |
| Schlenk, RF | 1 |
| Döhner, K | 1 |
| Teleanu, V | 1 |
| Bullinger, L | 1 |
| Nguyen, TM | 1 |
| Drognitz, K | 1 |
| Moulin, JC | 1 |
| Binnenhei, M | 1 |
| Bentz, M | 1 |
| Döhner, H | 1 |
| Bunjes, D | 1 |
| Kuchenbauer, F | 1 |
| Ringhoffer, M | 1 |
| Nishikawa, R | 1 |
| Christopoulos, P | 1 |
| Bertz, H | 1 |
| Ihorst, G | 1 |
| Marks, R | 1 |
| Wäsch, R | 1 |
| Finke, J | 1 |
| Bruserud, O | 1 |
| Reikvam, H | 1 |
| Kittang, AO | 1 |
| Ahmed, AB | 1 |
| Tvedt, TH | 1 |
| Sjo, M | 1 |
| Hatfield, KJ | 1 |
| Jang, GD | 1 |
| Kim, SW | 1 |
| Suh, CW | 1 |
| Kim, EK | 1 |
| Bahng, HS | 1 |
| Jeong, YH | 1 |
| Park, IG | 1 |
| Kim, WK | 1 |
| Kim, SH | 1 |
| Suh, EJ | 1 |
| Park, CJ | 1 |
| Ji, HS | 1 |
| Lee, JS | 1 |
| Locatelli, F | 1 |
| Labopin, M | 2 |
| Ortega, J | 1 |
| Meloni, G | 8 |
| Dini, G | 1 |
| Messina, C | 1 |
| Yaniv, I | 1 |
| Fagioli, F | 1 |
| Castel, V | 1 |
| Shaw, PJ | 1 |
| Ferrant, A | 1 |
| Pession, A | 1 |
| Sociè, G | 1 |
| Frassoni, F | 2 |
| Fouillard, L | 1 |
| Polge, E | 1 |
| Gorin, NC | 1 |
| Kalaycio, M | 1 |
| Rybicki, L | 1 |
| Pohlman, B | 1 |
| Sobecks, R | 1 |
| Ball, E | 1 |
| Cook, D | 1 |
| Andresen, S | 1 |
| Kuczkowski, E | 1 |
| Bolwell, B | 1 |
| Sirohi, B | 1 |
| Cunningham, D | 1 |
| Powles, R | 1 |
| Murphy, F | 1 |
| Arkenau, T | 1 |
| Norman, A | 1 |
| Oates, J | 1 |
| Wotherspoon, A | 1 |
| Horwich, A | 1 |
| Bartolucci, AA | 1 |
| Liu, C | 1 |
| Durant, JR | 1 |
| Gams, RA | 1 |
| Herman, TS | 1 |
| Durie, BG | 1 |
| Hutter, JJ | 1 |
| Wu, DP | 1 |
| Milpied, N | 2 |
| Moreau, P | 1 |
| Mechinaud-Lacroix, F | 1 |
| Mahe, B | 1 |
| Le Tortorec, S | 1 |
| Rapp, MJ | 1 |
| Bourdin, S | 1 |
| Mahe, JM | 1 |
| Harousseau, JL | 2 |
| Vignetti, M | 2 |
| Avvisati, G | 1 |
| Capria, S | 1 |
| Micozzi, A | 1 |
| Giona, F | 1 |
| Mandelli, F | 6 |
| Kiss, I | 1 |
| Tomasek, J | 1 |
| Vogl, SE | 1 |
| Presant, CA | 1 |
| Klahr, C | 1 |
| Santala, R | 1 |
| Rosenthal, S | 1 |
| Canellos, GP | 1 |
| Whang-Peng, J | 1 |
| Gralnick, HR | 1 |
| Sieber, SM | 1 |
| Adamson, RH | 1 |
| Clarkson, BD | 2 |
| Dowling, MD | 2 |
| Gee, TS | 2 |
| Cunningham, IB | 1 |
| Burchenal, JH | 2 |
| De Fabritiis, P | 4 |
| Petti, MC | 4 |
| Pinto, MR | 1 |
| Testi, AM | 1 |
| Vegna, ML | 1 |
| Briere, J | 1 |
| Desablens, B | 1 |
| Le Prise, PY | 1 |
| Ifrah, N | 1 |
| Gandhour, C | 1 |
| Casassus, P | 1 |
| Spinolo, JA | 1 |
| Dicke, KA | 1 |
| Horwitz, LJ | 1 |
| Jagannath, S | 1 |
| McCredie, K | 1 |
| Estey, E | 1 |
| Kantarjian, H | 1 |
| Zander, AR | 1 |
| Keating, M | 1 |
| Spitzer, G | 1 |
| Kolb, HJ | 1 |
| Bender-Götze, C | 1 |
| Haas, RJ | 1 |
| Holler, E | 1 |
| Thierfelder, S | 1 |
| Wilmanns, W | 1 |
| Amadori, S | 1 |
| Pulsoni, A | 2 |
| Sandrelli, A | 2 |
| Gribben, JG | 1 |
| Goldstone, AH | 1 |
| Linch, DC | 1 |
| MacMillan, AK | 1 |
| Richards, JD | 1 |
| Gerson, SL | 1 |
| Trey, JE | 1 |
| Covelli, A | 1 |
| Simone, F | 1 |
| Sayas, MJ | 1 |
| Sanz, MA | 1 |
| Martín-Aragonés, G | 1 |
| Javier Rafecas, F | 1 |
| Martínez, JA | 1 |
| Lorenzo, IJ | 1 |
| Sanz, GF | 1 |
| Gomis, F | 1 |
| Marty, ML | 1 |
| Sahakian, GJ | 1 |
| al-Mondhiry, H | 1 |
| Lacher, MJ | 1 |
| Connolly, CE | 1 |
| Frei, E | 1 |
| Schabel, FM | 1 |
| Goldin, A | 1 |
| Sakurai, M | 1 |
| Sandberg, AA | 1 |
| Gavosto, F | 1 |
| Haghbin, M | 1 |
| Cunningham, B | 1 |
| Tan, CT | 1 |
| Fairley, GH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intensive Conditioning Regimen With Thiotepa Combined With Busulfan, Fludarabine and Cytarabine for Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of Myeloid Malignancies With Extramedullary Involvement[NCT06111612] | 50 participants (Anticipated) | Observational | 2024-01-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for carmustine and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
[Treatment of glioma with temozolomide].
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro | 2009 |
High-dose etoposide in allogeneic stem cell transplantation.
Topics: Adenine Nucleotides; Anthracyclines; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chem | 2012 |
Combination chemotherapy in malignant diseases.
Topics: Adult; Antineoplastic Agents; Asparaginase; Carmustine; Child; Cyclophosphamide; Cytarabine; Cytosin | 1971 |
6 trials available for carmustine and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
CD8+ T-cell-depleted, matched unrelated donor, allogeneic bone marrow transplantation for advanced AML using busulfan-based preparative regimens.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Carmus | 2005 |
Acute myelogenous leukemia as a second malignant neoplasm following the successful treatment of advanced Hodgkin's disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Female; Hodgkin | 1983 |
BAVC regimen and autograft for acute myelogenous leukemia in second complete remission.
Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplant | 1996 |
[Autotransplantation in acute nonlymphoid leukemia].
Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transpla | 1991 |
BAVC regimen in CR AML patients.
Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplant | 1991 |
Bone marrow transplantation for the treatment of leukaemia-results of the Munich Cooperative Group.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Carmustine; Child; Child, Preschool; Cyclophosphamid | 1989 |
27 other studies available for carmustine and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
Reduced-toxicity conditioning for allogeneic hematopoietic cell transplantation in elderly or comorbid patients with AML using fludarabine, BCNU and melphalan: disease stage at transplant determines outcome.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Comorbidity; Female; Hematopoietic | 2018 |
Radiation-free allogeneic conditioning with fludarabine, carmustine, and thiotepa for acute lymphoblastic leukemia and other hematologic malignancies necessitating enhanced central nervous system activity.
Topics: Adult; Aged; Alemtuzumab; Antibodies, Monoclonal, Humanized; Carmustine; Central Nervous System; Cyc | 2012 |
A case of treatment-related myelodysplastic syndrome and acute myelogenous leukemia following high-dose chemotherapy with autologous stem cell transplantation for non-Hodgkin's lymphoma.
Topics: Adult; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocy | 2002 |
Factors influencing outcome and incidence of long-term complications in children who underwent autologous stem cell transplantation for acute myeloid leukemia in first complete remission.
Topics: Adolescent; Amsacrine; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bone Ma | 2003 |
Comparison of BAVC to BuCy regimens in autologous stem cell transplantation for adult patients with acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmus | 2004 |
Long-term outcome of autologous stem-cell transplantation in relapsed or refractory Hodgkin's lymphoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antin | 2008 |
Treatment of patients with refractory myelogenous leukemia with BCOMM[1,3-bis-chloro(2-chloroethyl)-1-nitrosourea (BCNU), oncovin (vincristine), cyclophosphamide, high-dose methotrexate and methyl-glyoxal bis-guanylhydrazone (MGBG)].
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine | 1982 |
Total body irradiation and high-dose cyclophosphamide, BCNU and VP-16 (CBV) as a new preparatory regimen for allogeneic bone marrow transplantation in patients with advanced hematologic malignancies.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carm | 1994 |
Sodium and potassium excretion changes and bone marrow recovery after chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carcinoma, Small Cell; | 1999 |
Acute leukemia complicating treatment of glioblastoma multiforme.
Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Child, Preschool; Dexamethasone; Drug Therapy, C | 1978 |
Amphotericin B induction of sensitivity to adriamycin, 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU) plus cyclophosphamide in human neoplasia.
Topics: Adult; Aged; Amphotericin B; Breast Neoplasms; Carmustine; Cyclophosphamide; Doxorubicin; Drug Resis | 1977 |
Blast crisis of chronic granulocytic leukemia. Morphologic variants and therapeutic implications.
Topics: Adult; Bone Marrow; Carmustine; Cytarabine; Diploidy; Drug Therapy, Combination; Female; Humans; Leu | 1977 |
Letter: Maintenance therapy in myeloma: risk versus benefit.
Topics: Carmustine; Humans; Leukemia, Myeloid, Acute; Melphalan; Multiple Myeloma; Prednisone | 1975 |
Treatment of acute leukemia in adults.
Topics: Adolescent; Adult; Aged; Asparaginase; Carmustine; Child; Cytarabine; Daunorubicin; Female; Humans; | 1975 |
Double intensive consolidation chemotherapy (ICC) for acute myeloid leukemia.
Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmu | 1990 |
BAVC regimen and autologous bone marrow transplantation in patients with acute myelogenous leukemia in second remission.
Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplant | 1990 |
High-dose chemotherapy and unpurged autologous bone marrow transplantation for acute leukemia in second or subsequent remission.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Comb | 1990 |
Autologous bone marrow transplantation in patients with AML in second complete remission (CR).
Topics: Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; | 1989 |
Double autologous bone marrow transplantation in acute myeloid leukaemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carm | 1989 |
Modulation of nitrosourea resistance in myeloid leukemias.
Topics: Carmustine; Cell Differentiation; Colony-Stimulating Factors; DNA Repair; Drug Resistance; Guanine; | 1988 |
Autologous bone marrow transplantation for patients with acute myelogenous leukemia in complete remission.
Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; | 1987 |
[Treatment of acute adult myeloblastic leukemia with intensive chemotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmustine; Combined Modality Thera | 1986 |
Acute leukemia in Hodgkin's disease.
Topics: Adult; Bleomycin; Carmustine; Chlorambucil; Drug Therapy, Combination; Female; Hodgkin Disease; Huma | 1974 |
Comparative chemotherapy of AKR lymphoma and human hematological neoplasia.
Topics: Animals; Antineoplastic Agents; Biological Assay; Carmustine; Cyclohexanes; Cyclophosphamide; Cytara | 1974 |
Chromosomes and causation of human cancer and leukemia. IX. Prognostic and therapeutic value of chromosomal findings in acute myeloblastic leukemia.
Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Bone Marrow Cells; Carmustine; Chromosome Aberratio | 1974 |
[Treatment of acute leukemia].
Topics: Antineoplastic Agents; Carmustine; Cyclophosphamide; Humans; Leukemia, Lymphoid; Leukemia, Monocytic | 1973 |
Comparative results obtained in the treatment of acute leukemia.
Topics: Antineoplastic Agents; Asparaginase; Carmustine; Cytarabine; Daunorubicin; Drug Therapy, Combination | 1973 |