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carmustine and Abnormalities, Drug-Induced

carmustine has been researched along with Abnormalities, Drug-Induced in 3 studies

Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research Excerpts

ExcerptRelevanceReference
"Procarbazine and BCNU were given for 5 months before conception and throughout the first and second trimesters, and streptozotocin was given throughout the third trimester."1.27Successful pregnancy following continuous treatment with combination chemotherapy before conception and throughout pregnancy. ( Chudley, AE; Schapira, DV, 1984)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schapira, DV1
Chudley, AE1
Thompson, DJ1
Molello, JA1
Strebing, RJ1
Dyke, IL1
Robinson, VB1

Other Studies

3 other studies available for carmustine and Abnormalities, Drug-Induced

ArticleYear
Successful pregnancy following continuous treatment with combination chemotherapy before conception and throughout pregnancy.
    Cancer, 1984, Sep-01, Volume: 54, Issue:5

    Topics: Abnormalities, Drug-Induced; Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Fema

1984
Bischloroethyl nitrosourea (BCNU).
    IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 1981, Volume: 26

    Topics: Abnormalities, Drug-Induced; Animals; Carcinogens; Carmustine; Chemical Phenomena; Chemistry; Drug I

1981
Reproduction and teratology studies with oncolytic agents in the rat and rabbit. I. I,3-bis(2-chloroethyl)-i-nitrosourea (BCNU).
    Toxicology and applied pharmacology, 1974, Volume: 30, Issue:3

    Topics: Abnormalities, Drug-Induced; Analysis of Variance; Animals; Animals, Newborn; Birth Weight; Body Wei

1974