carmustine has been researched along with Abnormalities, Autosome in 15 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carmustine (Cr) is an important chemotherapeutic drug, widely used in the treatment of brain tumors." | 1.72 | Protective role of Codiaeum variegatum against genotoxicity induced by carmustine in somatic and germ cells of male mice. ( Abd-Alla, HI; Fahmy, MA; Farghaly, AA; Hassan, EE; Hassan, ZM, 2022) |
| "Cytogenetic analysis showed complex chromosomal abnormalities including 11q23 rearrangement, which is frequently found in topoisomerase II inhibitor-related hematologic malignancies." | 1.31 | A case of treatment-related myelodysplastic syndrome and acute myelogenous leukemia following high-dose chemotherapy with autologous stem cell transplantation for non-Hodgkin's lymphoma. ( Bahng, HS; Jang, GD; Jeong, YH; Ji, HS; Kim, EK; Kim, SH; Kim, SW; Kim, WK; Lee, JS; Park, CJ; Park, IG; Suh, CW; Suh, EJ, 2002) |
| "Seven of ten anaplastic astrocytomas were composed primarily of 2n+/- cells and were BCNU resistant." | 1.29 | Chromosome number and carmustine sensitivity in human gliomas. ( Ebrahim, SA; Galicich, JH; Mohamed, AN; Pu, PY; Shapiro, JR; Shapiro, WR, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (40.00) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Fahmy, MA | 1 |
| Farghaly, AA | 1 |
| Hassan, EE | 1 |
| Hassan, ZM | 1 |
| Abd-Alla, HI | 1 |
| Jang, GD | 1 |
| Kim, SW | 1 |
| Suh, CW | 1 |
| Kim, EK | 1 |
| Bahng, HS | 1 |
| Jeong, YH | 1 |
| Park, IG | 1 |
| Kim, WK | 1 |
| Kim, SH | 1 |
| Suh, EJ | 1 |
| Park, CJ | 1 |
| Ji, HS | 1 |
| Lee, JS | 1 |
| Leuraud, P | 1 |
| Taillandier, L | 1 |
| Medioni, J | 1 |
| Aguirre-Cruz, L | 1 |
| Crinière, E | 1 |
| Marie, Y | 1 |
| Kujas, M | 1 |
| Golmard, JL | 1 |
| Duprez, A | 1 |
| Delattre, JY | 1 |
| Sanson, M | 1 |
| Poupon, MF | 1 |
| Shapiro, JR | 3 |
| Shapiro, WR | 2 |
| Kukushkina, GV | 1 |
| Peretolchina, NM | 1 |
| Minenkova, EA | 1 |
| Verovskiĭ, VN | 1 |
| Sof'ina, ZP | 1 |
| Scheck, AC | 1 |
| Mehta, BM | 1 |
| Beikman, MK | 1 |
| Ottaggio, L | 1 |
| Bonatti, S | 1 |
| Cavalieri, Z | 1 |
| Abbondandolo, A | 1 |
| Pu, PY | 1 |
| Mohamed, AN | 1 |
| Galicich, JH | 1 |
| Ebrahim, SA | 1 |
| Laughlin, MJ | 1 |
| McGaughey, DS | 1 |
| Crews, JR | 1 |
| Chao, NJ | 1 |
| Rizzieri, D | 1 |
| Ross, M | 1 |
| Gockerman, J | 1 |
| Cirrincione, C | 1 |
| Berry, D | 1 |
| Mills, L | 1 |
| Defusco, P | 1 |
| LeGrand, S | 1 |
| Peters, WP | 1 |
| Vredenburgh, JJ | 1 |
| Amigo, ML | 1 |
| del Cañizo, MC | 1 |
| Hernández, JM | 1 |
| Gonzalez, MB | 1 |
| Gutiérrez, N | 1 |
| Mateos, MV | 1 |
| San Miguel, JF | 1 |
| Bible, KC | 1 |
| Boerner, SA | 1 |
| Kirkland, K | 1 |
| Anderl, KL | 1 |
| Bartelt, D | 1 |
| Svingen, PA | 1 |
| Kottke, TJ | 1 |
| Lee, YK | 1 |
| Eckdahl, S | 1 |
| Stalboerger, PG | 1 |
| Jenkins, RB | 1 |
| Kaufmann, SH | 1 |
| Tates, AD | 1 |
| Natarajan, AT | 1 |
| De Vogel, N | 1 |
| Meijers, M | 1 |
| Hossfeld, DK | 1 |
| Tormey, D | 1 |
| Ellison, RR | 1 |
| Wiencke, JK | 1 |
| Bodell, WJ | 1 |
| Sakurai, M | 1 |
| Sandberg, AA | 1 |
1 review available for carmustine and Abnormalities, Autosome
| Article | Year |
|---|---|
Clonal tumor cell heterogeneity.
Topics: Brain Neoplasms; Carmustine; Chromosome Aberrations; Cisplatin; Culture Techniques; Drug Resistance; | 1984 |
14 other studies available for carmustine and Abnormalities, Autosome
| Article | Year |
|---|---|
Protective role of Codiaeum variegatum against genotoxicity induced by carmustine in somatic and germ cells of male mice.
Topics: Animals; Carmustine; Chromosome Aberrations; DNA Damage; Ethanol; Flavones; Male; Mice; Semen; Sperm | 2022 |
A case of treatment-related myelodysplastic syndrome and acute myelogenous leukemia following high-dose chemotherapy with autologous stem cell transplantation for non-Hodgkin's lymphoma.
Topics: Adult; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocy | 2002 |
Distinct responses of xenografted gliomas to different alkylating agents are related to histology and genetic alterations.
Topics: Animals; Antineoplastic Agents, Alkylating; Carboplatin; Carmustine; Chromosome Aberrations; Dacarba | 2004 |
[Disruption of DNA synthesis and structure of mouse L1210 leukemia cells, sensitive and resistant to 1-methyl-1 nitrosourea and 1,3-bis(2-chloroethyl)-1-nitrosourea in vivo].
Topics: Animals; Carmustine; Centrifugation, Density Gradient; Chromosome Aberrations; DNA, Neoplasm; DNA, S | 1984 |
BCNU-resistant human glioma cells with over-representation of chromosomes 7 and 22 demonstrate increased copy number and expression of platelet-derived growth factor genes.
Topics: Base Sequence; Biomarkers, Tumor; Blotting, Southern; Carmustine; Chromosome Aberrations; Chromosome | 1993 |
Chromosomes bearing amplified genes are a preferential target of chemicals inducing chromosome breakage and aneuploidy.
Topics: Aneuploidy; Animals; Aspartate Carbamoyltransferase; Carbamoyl-Phosphate Synthase (Glutamine-Hydroly | 1993 |
Chromosome number and carmustine sensitivity in human gliomas.
Topics: Adolescent; Adult; Aged; Aneuploidy; Astrocytoma; Brain Neoplasms; Carmustine; Child; Chromosome Abe | 1993 |
Secondary myelodysplasia and acute leukemia in breast cancer patients after autologous bone marrow transplant.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantat | 1998 |
Clonal myelodysplastic cells present in apheresis product before transplantation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chromosome Aberrations; Chromosomes, Hum | 1998 |
Characterization of an ovarian carcinoma cell line resistant to cisplatin and flavopiridol.
Topics: Antineoplastic Agents; Carmustine; Chromosome Aberrations; Chromosome Mapping; Cisplatin; DNA Adduct | 2000 |
A correlative study of the genetic damage induced by chemical mutagens in bone marrow and spermatogonia of mice. III. 1,3-Bis (2-chloroethyl)-3-nitrosourea (BCNU).
Topics: Animals; Bone Marrow; Bone Marrow Cells; Carmustine; Chromosome Aberrations; Dose-Response Relations | 1977 |
Ph1-positive megakaryoblastic leukemia.
Topics: Acute Disease; Autoradiography; Blood Cell Count; Blood Platelets; Bone Marrow; Carmustine; Chromoso | 1975 |
N-Methyl-N-nitrosourea potentiation of cytogenetic damage induced by 1,3-bis(2-chloroethyl)-1-nitrosourea in normal human lymphocytes.
Topics: Carmustine; Cell Cycle; Chromosome Aberrations; Drug Synergism; Humans; Lymphocytes; Methylnitrosour | 1985 |
Chromosomes and causation of human cancer and leukemia. IX. Prognostic and therapeutic value of chromosomal findings in acute myeloblastic leukemia.
Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Bone Marrow Cells; Carmustine; Chromosome Aberratio | 1974 |