Page last updated: 2024-10-24

carmofur and Local Neoplasm Recurrence

carmofur has been researched along with Local Neoplasm Recurrence in 18 studies

Research Excerpts

ExcerptRelevanceReference
"The direct effect and safety of carmofur (Mifurol) in cases of advanced and recurrent breast cancer were evaluated as a cooperative study at twenty-two facilities nationwide."9.08[Clinical effects of carmofur (Mifurol) on advanced and recurrent breast cancer in a cooperative study. Research association for re-evaluation of direct effects of Mifurol on breast cancer]. ( Abe, R; Enomoto, K; Koyama, H; Kusama, M; Nishi, T; Sonoo, H; Takashima, S; Tominaga, T; Yamaguchi, S; Yoshida, M, 1995)
"To evaluate the effect of 1-hexylcarbamoyl-5-fluorouracil (HCFU), a derivative of 5-fluorouracil (5-FU), in preventing postoperative recurrence of bladder cancer, a randomized controlled study with 1-(2-tetrahydrofuryl)-5-fluorouracil (Tegafur) as the reference standard was performed."9.05[A randomized controlled study to compare 1-hexylcarbamoyl-5-fluorouracil (HCFU) and 1-(2-tetrahydrofuryl)-5-fluorouracil (Tegafur) for the prevention of post-operative recurrence of bladder cancer]. ( Hisazumi, H; Kanda, S; Katsumi, T; Kawaguchi, K; Mikawa, I; Misaki, T; Miyagi, T; Nakamura, T; Orito, M; Sakai, A, 1985)
"This study was carried out to evaluate the effects of carmofur (Mifurol), a masked compound of 5-fluorouracil (5-FU), in preventing postoperative recurrence of urogenital carcinoma (especially in bladder cancer)."7.67[Study on effectiveness of carmofur (Mifurol) in urogenital carcinoma, especially bladder cancer, as a post-operative adjuvant chemotherapeutic agent]. ( Funai, K; Hayahara, N; Kawakita, J; Kishimoto, T; Maekawa, M; Morikawa, Y; Nishijima, T; Nishio, S; Yasumoto, R; Yuki, K, 1987)
"To treat superficial bladder cancer or invasive bladder cancer presenting as a solitary tumor, conservative therapy such as transurethral resection of bladder tumor or partial cystectomy has long been carried out."5.28[Study of preventive effect of 1-hexylcarbamoyl-5-fluorouracil (HCFU) or combination of HCFU and 2.5-di-O-acetyl-D-glucaro (1-4) (6-3) dilactone (SLA) after preservative operation against bladder cancer]. ( Hayahara, N; Horii, A; Kashihara, N; Kawakita, J; Kishimoto, T; Maekawa, M; Morikawa, Y; Nishijima, T; Wada, S; Yasumoto, R, 1992)
"The direct effect and safety of carmofur (Mifurol) in cases of advanced and recurrent breast cancer were evaluated as a cooperative study at twenty-two facilities nationwide."5.08[Clinical effects of carmofur (Mifurol) on advanced and recurrent breast cancer in a cooperative study. Research association for re-evaluation of direct effects of Mifurol on breast cancer]. ( Abe, R; Enomoto, K; Koyama, H; Kusama, M; Nishi, T; Sonoo, H; Takashima, S; Tominaga, T; Yamaguchi, S; Yoshida, M, 1995)
"To evaluate the effect of 1-hexylcarbamoyl-5-fluorouracil (HCFU), a derivative of 5-fluorouracil (5-FU), in preventing postoperative recurrence of bladder cancer, a randomized controlled study with 1-(2-tetrahydrofuryl)-5-fluorouracil (Tegafur) as the reference standard was performed."5.05[A randomized controlled study to compare 1-hexylcarbamoyl-5-fluorouracil (HCFU) and 1-(2-tetrahydrofuryl)-5-fluorouracil (Tegafur) for the prevention of post-operative recurrence of bladder cancer]. ( Hisazumi, H; Kanda, S; Katsumi, T; Kawaguchi, K; Mikawa, I; Misaki, T; Miyagi, T; Nakamura, T; Orito, M; Sakai, A, 1985)
"This study was carried out to evaluate the effects of carmofur (Mifurol), a masked compound of 5-fluorouracil (5-FU), in preventing postoperative recurrence of urogenital carcinoma (especially in bladder cancer)."3.67[Study on effectiveness of carmofur (Mifurol) in urogenital carcinoma, especially bladder cancer, as a post-operative adjuvant chemotherapeutic agent]. ( Funai, K; Hayahara, N; Kawakita, J; Kishimoto, T; Maekawa, M; Morikawa, Y; Nishijima, T; Nishio, S; Yasumoto, R; Yuki, K, 1987)
"Adjuvant therapy of colorectal cancer with oral fluorinated pyrimidines is attractive because of its ease of administration and good tolerability."2.42Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials. ( Burzykowski, T; Buyse, M; Hamada, C; Ohashi, Y; Piedbois, P; Sakamoto, J, 2004)
"Of them, 315 node-negative stage II colorectal cancer cases were enrolled."1.43Micrometastasis Volume in Lymph Nodes Determines Disease Recurrence Rate of Stage II Colorectal Cancer: A Prospective Multicenter Trial. ( Doki, Y; Fukunaga, M; Ikeda, M; Kato, T; Matsuura, N; Miyake, Y; Mizushima, T; Monden, M; Mori, M; Murata, K; Nakamura, Y; Nezu, R; Noura, S; Ohnishi, T; Ohtsuka, M; Ohue, M; Sekimoto, M; Takemasa, I; Yamamoto, H, 2016)
" After right lobectomy of the liver which contained the tumors of S6 2 cm and S8 3 cm in diameter 7 months before, the patient was treated with hepatic arterial embolization (TAE) combined with infusion of anti-cancer drug (ADM, CDDP) four times since June 1990."1.28[A case report of postoperative recurrent hepatocellular carcinoma effectively treated with HCFU administration combined with TAE]. ( Imai, Y; Ito, J; Kobayashi, K; Okamoto, M; Tagawa, K; Taniguchi, M; Tanzawa, Y; Toda, N; Unuma, T; Uta, Y, 1992)
"To treat superficial bladder cancer or invasive bladder cancer presenting as a solitary tumor, conservative therapy such as transurethral resection of bladder tumor or partial cystectomy has long been carried out."1.28[Study of preventive effect of 1-hexylcarbamoyl-5-fluorouracil (HCFU) or combination of HCFU and 2.5-di-O-acetyl-D-glucaro (1-4) (6-3) dilactone (SLA) after preservative operation against bladder cancer]. ( Hayahara, N; Horii, A; Kashihara, N; Kawakita, J; Kishimoto, T; Maekawa, M; Morikawa, Y; Nishijima, T; Wada, S; Yasumoto, R, 1992)
"A 51-year-old man with recurrent gastric cancer was treated by combined administration of Cisplatin and Carmofur."1.27[A case of recurrent gastric cancer successfully treated with a combination of cisplatin and carmofur]. ( Abe, S; Akazawa, S; Fujiki, T; Futatsuki, K; Kanda, Y; Kuwatsuru, R; Saifuku, K; Yamamoto, K; Yoon, S; Yoshida, K, 1987)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19905 (27.78)18.7374
1990's9 (50.00)18.2507
2000's3 (16.67)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yamamoto, H1
Murata, K1
Fukunaga, M1
Ohnishi, T1
Noura, S1
Miyake, Y1
Kato, T1
Ohtsuka, M1
Nakamura, Y1
Takemasa, I1
Mizushima, T1
Ikeda, M2
Ohue, M1
Sekimoto, M1
Nezu, R1
Matsuura, N1
Monden, M1
Doki, Y1
Mori, M1
Sakamoto, J2
Ohashi, Y2
Hamada, C2
Buyse, M1
Burzykowski, T1
Piedbois, P1
Rahman, M1
Kodaira, S1
Ito, K1
Nakazato, H1
Yasutomi, M1
Kusama, M1
Tominaga, T1
Enomoto, K1
Yoshida, M1
Koyama, H1
Sonoo, H1
Takashima, S1
Abe, R1
Nishi, T1
Yamaguchi, S1
Teshima, K1
Noda, K1
Yamagata, S1
Sugawa, T1
Okamura, S1
Kubo, H1
Sugimoto, O1
Nakajima, H1
Yamabe, T1
Katsumata, K1
Yamashita, S1
Hoshino, S1
Tani, C1
Yamamoto, K2
Kimura, K1
Yamamoto, M1
Arii, S1
Sugahara, K1
Tobe, T1
Ono, T2
Nagasue, N2
Kohno, H2
Hayashi, T1
Uchida, M1
Yukaya, H1
Yamanoi, A2
Nazmy El Assal, O1
Imai, Y1
Ito, J1
Tanzawa, Y1
Toda, N1
Okamoto, M1
Kobayashi, K1
Taniguchi, M1
Uta, Y1
Tagawa, K1
Unuma, T1
Okuyama, K1
Awano, T1
Tohnosu, N1
Koide, Y1
Matsubara, H1
Nakaichi, H1
Funami, Y1
Matsushita, K1
Amano, H1
Ochiai, T1
Wada, S1
Yasumoto, R2
Kashihara, N1
Kishimoto, T2
Maekawa, M2
Hayahara, N2
Kawakita, J2
Nishijima, T2
Morikawa, Y2
Horii, A1
Moriya, Y1
Sugihara, K1
Hojo, K1
Makuuchi, M1
Sawada, M2
Nishio, S1
Funai, K1
Yuki, K1
Ozaki, M1
Hongo, J1
Hirota, Y1
Inagaki, M1
Kuwatsuru, R1
Akazawa, S1
Yoon, S1
Yoshida, K1
Saifuku, K1
Abe, S1
Fujiki, T1
Kanda, Y1
Futatsuki, K1
Misaki, T1
Hisazumi, H1
Sakai, A1
Nakamura, T1
Kanda, S1
Mikawa, I1
Miyagi, T1
Katsumi, T1
Orito, M1
Kawaguchi, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Donafenib Combined With TACE as Adjuvant Therapy of Patients With Hepatocellular Carcinoma at a High Risk of Recurrence After Radical Resection[NCT05161143]Phase 230 participants (Anticipated)Interventional2021-12-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for carmofur and Local Neoplasm Recurrence

ArticleYear
Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Feb-01, Volume: 22, Issue:3

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2004
An individual patient data meta-analysis of adjuvant therapy with carmofur in patients with curatively resected colon cancer.
    Japanese journal of clinical oncology, 2005, Volume: 35, Issue:9

    Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Colonic Neoplasms; Digestive System Surgical Procedur

2005
Adjuvant chemotherapy after resection of hepatocellular carcinoma causes deterioration of long-term prognosis in cirrhotic patients: metaanalysis of three randomized controlled trials.
    Cancer, 2001, Jun-15, Volume: 91, Issue:12

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Hepa

2001

Trials

5 trials available for carmofur and Local Neoplasm Recurrence

ArticleYear
[Clinical effects of carmofur (Mifurol) on advanced and recurrent breast cancer in a cooperative study. Research association for re-evaluation of direct effects of Mifurol on breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:4

    Topics: Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Agents; Breast Neoplasms; Dizziness; Dru

1995
[Long-term administration of carmofur as a post-operative adjuvant chemotherapy for cervical adenocarcinoma. Cervical Adenocarcinoma Cooperative Research Association].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:12

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell;

1994
Adjuvant oral chemotherapy to prevent recurrence after curative resection for hepatocellular carcinoma.
    The British journal of surgery, 1996, Volume: 83, Issue:3

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Disease-Free Survival; Flu

1996
Adjuvant chemotherapy with epirubicin and carmofur after radical resection of hepatocellular carcinoma: a prospective randomized study.
    Seminars in oncology, 1997, Volume: 24, Issue:2 Suppl 6

    Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellul

1997
[A randomized controlled study to compare 1-hexylcarbamoyl-5-fluorouracil (HCFU) and 1-(2-tetrahydrofuryl)-5-fluorouracil (Tegafur) for the prevention of post-operative recurrence of bladder cancer].
    Hinyokika kiyo. Acta urologica Japonica, 1985, Volume: 31, Issue:7

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Drug Administrat

1985

Other Studies

10 other studies available for carmofur and Local Neoplasm Recurrence

ArticleYear
Micrometastasis Volume in Lymph Nodes Determines Disease Recurrence Rate of Stage II Colorectal Cancer: A Prospective Multicenter Trial.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2016, 07-01, Volume: 22, Issue:13

    Topics: Aged; Antineoplastic Agents; Biomarkers, Tumor; Carcinoembryonic Antigen; Colorectal Neoplasms; Dise

2016
[Evaluation of neoadjuvant combination chemotherapy with pirarubicin, carmofur and tamoxifen citrate on outpatients with advanced and recurrence breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:2

    Topics: Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherap

1994
[A case report of postoperative recurrent hepatocellular carcinoma effectively treated with HCFU administration combined with TAE].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:6

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Combined Modality Therapy; Embolization, Therapeut

1992
[Signification of liver metastases of colorectal cancer with special reference to recurrence in the residual liver after hepatic resection].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:10 Suppl

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Doxorubi

1992
[Study of preventive effect of 1-hexylcarbamoyl-5-fluorouracil (HCFU) or combination of HCFU and 2.5-di-O-acetyl-D-glucaro (1-4) (6-3) dilactone (SLA) after preservative operation against bladder cancer].
    Hinyokika kiyo. Acta urologica Japonica, 1992, Volume: 38, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitio

1992
Adjuvant hepatic intra-arterial chemotherapy after potentially curative hepatectomy for liver metastases from colorectal cancer: a pilot study.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1991, Volume: 17, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neop

1991
[Experimental chemotherapy of ovarian cancers heterotransplanted in nude mice].
    Nihon Sanka Fujinka Gakkai zasshi, 1985, Volume: 37, Issue:8

    Topics: Adenocarcinoma, Mucinous; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Proto

1985
[Study on effectiveness of carmofur (Mifurol) in urogenital carcinoma, especially bladder cancer, as a post-operative adjuvant chemotherapeutic agent].
    Hinyokika kiyo. Acta urologica Japonica, 1987, Volume: 33, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Combined Modality Thera

1987
[Effect of post operative maintenance chemotherapy against ovarian cancer].
    Nihon Sanka Fujinka Gakkai zasshi, 1987, Volume: 39, Issue:7

    Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Humans; Mice; Mice,

1987
[A case of recurrent gastric cancer successfully treated with a combination of cisplatin and carmofur].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:11

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administrat

1987