carmofur has been researched along with Cancer of Stomach in 30 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Experimental chemotherapy with 5-fluorouracil (5-FU; 60 mg/kg), 1-hexylcarbamoyl-5-fluorouracil (HCFU; 70 mg/kg), 3-(3-(6-benzoyloxy-3-cyano-2-pyridyloxycarbonyl)benzoyl)-1-ethoxym ethyl-5- fluorouracil (BOF-A2; 30 mg/kg) and UFT (20 mg/kg as tegafur with uracil at a molar ratio of 1:4) was performed using human gastric (H-111) and colon (Co-4) carcinoma strains in nude mice." | 3.68 | Antitumor activity of fluoropyrimidines and thymidylate synthetase inhibition. ( Abe, O; Arisawa, Y; Fujita, S; Ishibiki, K; Josui, K; Kodaira, S; Kubota, T; Mabuchi, K; Suto, A; Yamamoto, T, 1991) |
| "To evaluate the efficacy of adjuvant immunochemotherapy, especially the long-term administration of HCFU to patients with noncuratively resected and unresected gastric cancer, a randomized controlled study was conducted by 16 institutions in Hokkaido." | 2.68 | [Randomized controlled study on adjuvant immunochemotherapy with carmofur (HCFU) for noncuratively resected and unresected gastric cancer]. ( Fujisawa, J; Kondo, Y; Miyakawa, K; Nakanishi, Y; Nishimura, A; Oku, T; Osawa, S; Shiroto, H; Uchino, J, 1996) |
| "The cumulative survival rate of 166 gastric cancer patients after noncurative resection and nonresection treated by combination therapy using carmofur (HCFU), mitomycin C (MMC) and immunopotentiators was investigated." | 2.66 | [A randomized controlled trial of immunochemotherapy using carmofur (HCFU), mitomycin C and immunopotentiators in advanced gastric cancer following noncurative resection and nonresection]. ( Nakanishi, Y, 1986) |
| "Though treatment of recurrent gastric cancer with liver metastasis is often ineffective, this case suggests that a combination therapy of cisplatin and carmofur might be effective." | 1.30 | [A case of recurrent gastric cancer with liver metastasis responding to combination chemotherapy with cisplatin and carmofur]. ( Inomata, Y; Inoue, K; Kuroda, T; Mizutani, H; Sakuyama, T; Tadaoka, N; Takahashi, N; Yamada, T; Yoshinaga, K, 1997) |
| "Lung metastasis in mice bearing subcutaneous tumors was significantly inhibited by HCFU at doses of 100-150 mg kg(-1) day(-1) without severe toxic side-effects, when orally administered three times per week either from week 4 or week 6 to 9 weeks after implantation." | 1.30 | Induction of apoptosis in metastatic foci from human gastric cancer xenografts in nude mice and reduction of circulating tumor cells in blood by 5-FU and 1-hexylcarbamoyl-5-fluorouracil. ( Abe, A; Inada, K; Nakanishi, H; Tatematsu, M; Tsukamoto, T; Yasui, K, 1999) |
| "Feasibility of utilizing human gastric cancers as first transplant generation xenografts in nude mice for determining tumor sensitivity to chemotherapeutic agents was demonstrated by applying subrenal capsule (SRC) assay." | 1.28 | Subrenal capsule assay using nude mice as a predictor of the response of the gastric cancer to chemotherapy. ( Akiyama, S; Ito, A; Ito, K; Kondo, K; Satta, T; Takagi, H; Watanabe, T; Yamauchi, M, 1991) |
| "The cases were comprised of 9 gastric cancers, 6 colorectal cancers, 1 appendiceal carcinoma, and 1 malignant tumor of retroperitoneum, all of which were observed to have peritoneal dissemination during surgical operations." | 1.28 | [Evaluation of intraperitoneal cancer chemotherapy using an implantable reservoir in patients with peritonitis carcinomatosa]. ( Katsuki, Y; Nishimura, A; Tsuji, Y; Yasuda, T, 1990) |
| "Six patients with hepatocellular carcinoma (HCC) and 9 patients with metastatic liver carcinoma (MLC) (4 with stomach cancer, 4 with pancreas cancer and 1 with colon cancer) were treated with rapid hepatic artery infusion of adriamycin." | 1.27 | [Intraarterial Adriamycin for patients with hepatocellular carcinoma and metastatic liver carcinoma]. ( Hino, I; Kimura, I; Kuroda, S; Numoto, A; Ohnoshi, T; Takahashi, M; Tsuji, M; Ueoka, H, 1984) |
| "The sensitivity of human gastric cancer tissue to 5-fluorouracil (5-FU) and its analogues 1-(2-tetrahydrofuryl)-5-fluorouracil (FT), UFT and 1-hexylcarbamoyl-5-fluorouracil (HCFU) was determined, using the in vivo subrenal capsule (SRC) assay." | 1.27 | UFT is more antineoplastic against gastric carcinoma than 5-fluorouracil, 1-(2-tetrahydrofuryl)-5-fluorouracil and 1-hexylcarbamoyl-5-fluorouracil. ( Anai, H; Kusumoto, H; Kusumoto, T; Maehara, Y; Sugimachi, K, 1988) |
| "A 51-year-old man with recurrent gastric cancer was treated by combined administration of Cisplatin and Carmofur." | 1.27 | [A case of recurrent gastric cancer successfully treated with a combination of cisplatin and carmofur]. ( Abe, S; Akazawa, S; Fujiki, T; Futatsuki, K; Kanda, Y; Kuwatsuru, R; Saifuku, K; Yamamoto, K; Yoon, S; Yoshida, K, 1987) |
| "For the diffuse invasive type of gastric cancer, the changes in the X-ray finding such as stiffness and poor elasticity of gastric wall and malignant relief were also taken into consideration for the judgement." | 1.26 | [Evaluation of the therapeutic effect of HCFU (1-hexylcarbamoyl-5-fluorouracil) on non-resectable stomach cancer]. ( Chin, F; Hirasawa, H; Isono, K; Kimura, M; Kouzu, T; Okuyama, K; Onoda, S; Ryu, M; Sato, H; Satoh, H; Tounosu, N; Yamamoto, Y, 1982) |
| "After confirming the presence of gastric cancer, 1-n-hexylcarbamoyl-5-fluorouracil (HCFU), a derivative of 5-fluorouracil, was given to the dogs orally as capsules at a daily dose of 5 or 10 mg/kg body weight." | 1.26 | Chemotherapeutic study on canine gastric cancer induced by N-ethyl-N'-nitro-N-nitrosoguanidine. ( Aoyagi, M; Hirashima, T; Hirota, T; Kawachi, T; Matsukura, N; Sugimura, T; Takasugi, T; Uchida, E; Ushio, K; Yoshida, S, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (60.00) | 18.7374 |
| 1990's | 10 (33.33) | 18.2507 |
| 2000's | 2 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ueoka, H | 1 |
| Kuroda, S | 1 |
| Ohnoshi, T | 1 |
| Kimura, I | 1 |
| Numoto, A | 1 |
| Hino, I | 1 |
| Takahashi, M | 1 |
| Tsuji, M | 1 |
| Akazawa, S | 2 |
| Honda, T | 1 |
| Sampi, K | 1 |
| Nakagawa, T | 1 |
| Fujiki, T | 2 |
| Kanda, Y | 2 |
| Futatsuki, K | 2 |
| Izuno, O | 1 |
| Suda, Y | 1 |
| Katayama, K | 1 |
| Yoshitake, Y | 1 |
| Sato, H | 1 |
| Satoh, H | 1 |
| Isono, K | 1 |
| Onoda, S | 1 |
| Okuyama, K | 1 |
| Tounosu, N | 1 |
| Yamamoto, Y | 1 |
| Kimura, M | 1 |
| Chin, F | 1 |
| Kouzu, T | 1 |
| Ryu, M | 1 |
| Hirasawa, H | 1 |
| Koyama, Y | 1 |
| Matsukura, N | 1 |
| Aoyagi, M | 1 |
| Kawachi, T | 1 |
| Uchida, E | 1 |
| Yoshida, S | 1 |
| Hirashima, T | 1 |
| Takasugi, T | 1 |
| Ushio, K | 1 |
| Hirota, T | 1 |
| Sugimura, T | 1 |
| Yamaguchi, R | 1 |
| Yamaguchi, A | 1 |
| Isogai, M | 1 |
| Hori, A | 1 |
| Kin, Y | 1 |
| Osawa, S | 1 |
| Shiroto, H | 1 |
| Kondo, Y | 1 |
| Nakanishi, Y | 2 |
| Fujisawa, J | 1 |
| Miyakawa, K | 1 |
| Oku, T | 1 |
| Nishimura, A | 2 |
| Uchino, J | 1 |
| Tadaoka, N | 1 |
| Takahashi, N | 1 |
| Yoshinaga, K | 1 |
| Yamada, T | 1 |
| Inoue, K | 1 |
| Mizutani, H | 1 |
| Inomata, Y | 1 |
| Sakuyama, T | 1 |
| Kuroda, T | 1 |
| Nakanishi, H | 1 |
| Abe, A | 1 |
| Inada, K | 1 |
| Tsukamoto, T | 1 |
| Yasui, K | 1 |
| Tatematsu, M | 1 |
| Tokuda, C | 1 |
| Miyama, Y | 1 |
| Takeda, H | 1 |
| Fukui, H | 1 |
| Kageyama, T | 1 |
| Toizumi, A | 1 |
| Tamura, Y | 1 |
| Kuroda, Y | 1 |
| Ohkuma, R | 1 |
| Ohsato, K | 1 |
| Kubota, T | 1 |
| Fujita, S | 1 |
| Kodaira, S | 1 |
| Yamamoto, T | 1 |
| Josui, K | 1 |
| Arisawa, Y | 1 |
| Suto, A | 1 |
| Ishibiki, K | 1 |
| Abe, O | 2 |
| Mabuchi, K | 1 |
| Yamauchi, M | 1 |
| Satta, T | 1 |
| Ito, A | 1 |
| Kondo, K | 1 |
| Akiyama, S | 1 |
| Ito, K | 1 |
| Watanabe, T | 1 |
| Takagi, H | 1 |
| Tsuji, Y | 1 |
| Katsuki, Y | 1 |
| Yasuda, T | 1 |
| Gröhn, P | 1 |
| Heinonen, E | 1 |
| Kumpulainen, E | 1 |
| Länsimies, H | 1 |
| Lantto, A | 1 |
| Salmi, R | 1 |
| Pyrhönen, S | 1 |
| Numminen, S | 1 |
| Nakatani, K | 2 |
| Watanabe, A | 1 |
| Nishiwada, T | 1 |
| Sawada, H | 1 |
| Okumura, T | 1 |
| Yamada, Y | 1 |
| Yano, T | 1 |
| Shino, Y | 1 |
| Nakano, H | 1 |
| Kunii, Y | 1 |
| Kikuchi, K | 1 |
| Tanabe, T | 1 |
| Kondo, T | 1 |
| Taguchi, T | 1 |
| Hattori, T | 3 |
| Komi, N | 1 |
| Nakazato, H | 4 |
| Nakajima, T | 1 |
| Nishiyama, M | 2 |
| Takagami, S | 2 |
| Kirihara, Y | 2 |
| Saeki, T | 2 |
| Hirabayashi, N | 1 |
| Nosoh, Y | 1 |
| Niimoto, M | 2 |
| Koike, A | 3 |
| Ichihashi, H | 2 |
| Anai, H | 2 |
| Maehara, Y | 2 |
| Kusumoto, H | 2 |
| Masuda, H | 1 |
| Sugimachi, K | 2 |
| Yamamura, Y | 1 |
| Kusumoto, T | 1 |
| Kim, R | 1 |
| Jinushi, K | 1 |
| Kuwatsuru, R | 1 |
| Yoon, S | 1 |
| Yamamoto, K | 1 |
| Yoshida, K | 1 |
| Saifuku, K | 1 |
| Abe, S | 1 |
| Ichihashi, S | 1 |
| Asakawa, H | 1 |
| Koyama, K | 1 |
| Otake, S | 1 |
| Otawa, H | 1 |
| Ezaki, T | 1 |
| Sakamoto, K | 1 |
| Sugizaki, T | 1 |
| Miyagi, N | 1 |
5 trials available for carmofur and Cancer of Stomach
| Article | Year |
|---|---|
[Randomized controlled study on adjuvant immunochemotherapy with carmofur (HCFU) for noncuratively resected and unresected gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Chi-Square Distribution; Com | 1996 |
[Adjuvant chemotherapy for gastric cancer--the third study. First report: central randomization by telephone method and analysis of patients' background factors].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Drug Administ | 1989 |
[A randomized controlled trial comparing short-term MF chemotherapy with MF and long-term carmofur chemotherapy as an adjuvant to curative resection of stomach cancer].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Dru | 1986 |
[A randomized controlled trial of immunochemotherapy using carmofur (HCFU), mitomycin C and immunopotentiators in advanced gastric cancer following noncurative resection and nonresection].
Topics: Adjuvants, Immunologic; Adult; Aged; Clinical Trials as Topic; Drug Administration Schedule; Female; | 1986 |
[A randomized controlled trial comparing short-term MF chemotherapy with MF plus long-term HCFU chemotherapy as an adjuvant to a curative resection of stomach cancer: Mifurol Study Group for Stomach Cancer].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Clinical Trials as | 1988 |
25 other studies available for carmofur and Cancer of Stomach
| Article | Year |
|---|---|
[Intraarterial Adriamycin for patients with hepatocellular carcinoma and metastatic liver carcinoma].
Topics: Adult; Aged; Alkaline Phosphatase; Carcinoma, Hepatocellular; Doxorubicin; Drug Administration Sched | 1984 |
[Combination chemotherapy of CIS-diamminedichloroplatinum (II) and fluoropyrimidine derivatives for advanced gastric cancer: a preliminary report].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluo | 1984 |
[Blood concentration of HCFU in gastrectomized patients].
Topics: Fluorouracil; Gastrectomy; Humans; Postoperative Period; Stomach Neoplasms | 1984 |
[Evaluation of the therapeutic effect of HCFU (1-hexylcarbamoyl-5-fluorouracil) on non-resectable stomach cancer].
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Agents; Drug Evaluation; Female; F | 1982 |
[Phase II study of carmofur (HCFU) fine granules].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Child; Child, Preschool; Colonic N | 1982 |
Chemotherapeutic study on canine gastric cancer induced by N-ethyl-N'-nitro-N-nitrosoguanidine.
Topics: Adenocarcinoma; Animals; Dogs; Fluorouracil; Humans; Male; Methylnitronitrosoguanidine; Stomach Neop | 1980 |
[Study on the combined preoperative treatment with CDDP and HCFU for gastric cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; F | 1996 |
[A case of recurrent gastric cancer with liver metastasis responding to combination chemotherapy with cisplatin and carmofur].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Fluor | 1997 |
Induction of apoptosis in metastatic foci from human gastric cancer xenografts in nude mice and reduction of circulating tumor cells in blood by 5-FU and 1-hexylcarbamoyl-5-fluorouracil.
Topics: Animals; Antigens, Nuclear; Antineoplastic Agents; Apoptosis; Cell Division; Dose-Response Relations | 1999 |
[Antitumor activity of 1-hexylcarbamoyluracil which is carmofur substituted fluorine for hydrogen].
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Female; Fluorouracil; Mice; Mice, Inbred BALB C; | 2000 |
[Inhibition of HCFU absorption after resection for gastric cancer--application of hydroxyaluminium gel].
Topics: Adult; Aged; Aluminum Hydroxide; Antineoplastic Agents; Chemotherapy, Adjuvant; Cross-Over Studies; | 2001 |
[Serum concentration of HCFU and 5-FU after oral administration of HCFU in postoperative digestive cancer patients].
Topics: Administration, Oral; Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; Gastrectomy; Humans; S | 1992 |
Antitumor activity of fluoropyrimidines and thymidylate synthetase inhibition.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma; Colonic Neoplasms; Enzyme Activation; Flu | 1991 |
Subrenal capsule assay using nude mice as a predictor of the response of the gastric cancer to chemotherapy.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Fluorouracil; Huma | 1991 |
[Evaluation of intraperitoneal cancer chemotherapy using an implantable reservoir in patients with peritonitis carcinomatosa].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Cisplatin; Colorectal Ne | 1990 |
Oral carmofur in advanced gastrointestinal cancer.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Drug Admini | 1990 |
[Effect of concomitant use of anticancer drugs and a Ca2+ antagonist, on human gastric cancer transplanted into nude mice].
Topics: Animals; Antineoplastic Agents; Drug Combinations; Fluorouracil; Humans; Male; Mice; Mice, Inbred BA | 1990 |
The antiproliferative effects of fluoropyrimidine derivatives against human tumor xenografts in a subrenal capsule assay.
Topics: Animals; Antineoplastic Agents; Body Weight; Cell Division; Colorectal Neoplasms; Floxuridine; Fluor | 1988 |
[Chemosensitivity testing for 5-FU and 5-FU derivatives using subrenal capsule assay].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colony-Forming Units Assay; Fluor | 1987 |
UFT is more antineoplastic against gastric carcinoma than 5-fluorouracil, 1-(2-tetrahydrofuryl)-5-fluorouracil and 1-hexylcarbamoyl-5-fluorouracil.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Male; Mice; Stomach Neoplasms | 1988 |
[Inhibition of thymidylate synthetase and antiproliferative effect by 1-hexylcarbamoyl-5-fluorouracil].
Topics: Animals; Antineoplastic Agents; Cell Division; Esophageal Neoplasms; Fluorouracil; Mice; Mice, Inbre | 1988 |
[A case of recurrent gastric cancer successfully treated with a combination of cisplatin and carmofur].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administrat | 1987 |
[The dose finding of adjuvant carmofur chemotherapy in patients with stomach cancer].
Topics: Drug Administration Schedule; Fluorouracil; Humans; Stomach Neoplasms | 1986 |
[Evaluation of combined radiotherapy of gastric carcinoma].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera | 1985 |
[Effects of combination therapy of carmofur and nicardipine of human gastric cancer in nude mice].
Topics: Animals; Cell Line; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Humans; Male; Mice; Mic | 1985 |