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carmofur and Adenocarcinoma, Basal Cell

carmofur has been researched along with Adenocarcinoma, Basal Cell in 18 studies

Research Excerpts

ExcerptRelevanceReference
"The aim of the study was to define the maximum tolerated dose (MTD) of the combination of raltitrexed plus carmofur, and to evaluate the tolerability and efficacy of this combination in metastatic colorectal cancer."7.71A phase I study of raltitrexed (Tomudex) combined with carmofur in metastatic colorectal cancer. ( Elomaa, I; Joensuu, H; Osterlund, P; Virkkunen, P, 2001)
"The antitumor activity of 1-hexylcarbamoyl-5-fluorouracil (HCFU) in various schedules of long-term oral administration was examined in spontaneous mammary adenocarcinoma of SHN mice, an autochthonous tumor system."7.66Effect of 1-hexylcarbamoyl-5-fluorouracil on spontaneous mammary adenocarcinoma of mice. ( Hoshi, A; Iigo, M; Kuretani, K; Tokuzen, R, 1980)
"1-Hexylcarbamoyl-5-fluorouracil (HCFU) and its parent compound 5-fluorouracil (5-FU) were tested PO for antitumor activity against mouse colon adenocarcinoma 26 (colon 26), colon adenocarcinoma 38 (colon 38), and Lewis lung carcinoma."7.66Inhibition of murine colon adenocarcinomas and Lewis lung carcinoma by 1-hexylcarbamoyl-5-fluorouracil. ( Iida, H; Naganuma, K; Sakurai, Y; Tsukagoshi, S; Tsuruo, T, 1980)
"We studied longitudinally inflammatory reactions and serum C-reactive protein (S-CRP) levels in 52 colorectal cancer patients treated with a median of six 3-weekly cycles of raltitrexed 1."3.71Raltitrexed treatment promotes systemic inflammatory reaction in patients with colorectal carcinoma. ( Elomaa, I; Joensuu, H; Orpana, A; Osterlund, P; Repo, H, 2002)
"The aim of the study was to define the maximum tolerated dose (MTD) of the combination of raltitrexed plus carmofur, and to evaluate the tolerability and efficacy of this combination in metastatic colorectal cancer."3.71A phase I study of raltitrexed (Tomudex) combined with carmofur in metastatic colorectal cancer. ( Elomaa, I; Joensuu, H; Osterlund, P; Virkkunen, P, 2001)
"Experimental chemotherapy with 5-fluorouracil (5-FU; 60 mg/kg), 1-hexylcarbamoyl-5-fluorouracil (HCFU; 70 mg/kg), 3-(3-(6-benzoyloxy-3-cyano-2-pyridyloxycarbonyl)benzoyl)-1-ethoxym ethyl-5- fluorouracil (BOF-A2; 30 mg/kg) and UFT (20 mg/kg as tegafur with uracil at a molar ratio of 1:4) was performed using human gastric (H-111) and colon (Co-4) carcinoma strains in nude mice."3.68Antitumor activity of fluoropyrimidines and thymidylate synthetase inhibition. ( Abe, O; Arisawa, Y; Fujita, S; Ishibiki, K; Josui, K; Kodaira, S; Kubota, T; Mabuchi, K; Suto, A; Yamamoto, T, 1991)
"The combined effects of X-ray irradiation and 5-FU derivatives (5-FU, tegafur, HCFU) treatment were investigated in mouse adenocarcinoma-755."3.67[Combined effects of radiation and 5-FU derivatives]. ( Dokiya, T; Hashimoto, S; Kunieda, E; Miyamoto, H; Shigematsu, N; Tominaga, J, 1986)
"The antitumor activity of 1-hexylcarbamoyl-5-fluorouracil (HCFU) in various schedules of long-term oral administration was examined in spontaneous mammary adenocarcinoma of SHN mice, an autochthonous tumor system."3.66Effect of 1-hexylcarbamoyl-5-fluorouracil on spontaneous mammary adenocarcinoma of mice. ( Hoshi, A; Iigo, M; Kuretani, K; Tokuzen, R, 1980)
"1-Hexylcarbamoyl-5-fluorouracil (HCFU) and its parent compound 5-fluorouracil (5-FU) were tested PO for antitumor activity against mouse colon adenocarcinoma 26 (colon 26), colon adenocarcinoma 38 (colon 38), and Lewis lung carcinoma."3.66Inhibition of murine colon adenocarcinomas and Lewis lung carcinoma by 1-hexylcarbamoyl-5-fluorouracil. ( Iida, H; Naganuma, K; Sakurai, Y; Tsukagoshi, S; Tsuruo, T, 1980)
"Feasibility of utilizing human gastric cancers as first transplant generation xenografts in nude mice for determining tumor sensitivity to chemotherapeutic agents was demonstrated by applying subrenal capsule (SRC) assay."1.28Subrenal capsule assay using nude mice as a predictor of the response of the gastric cancer to chemotherapy. ( Akiyama, S; Ito, A; Ito, K; Kondo, K; Satta, T; Takagi, H; Watanabe, T; Yamauchi, M, 1991)
"For the diffuse invasive type of gastric cancer, the changes in the X-ray finding such as stiffness and poor elasticity of gastric wall and malignant relief were also taken into consideration for the judgement."1.26[Evaluation of the therapeutic effect of HCFU (1-hexylcarbamoyl-5-fluorouracil) on non-resectable stomach cancer]. ( Chin, F; Hirasawa, H; Isono, K; Kimura, M; Kouzu, T; Okuyama, K; Onoda, S; Ryu, M; Sato, H; Satoh, H; Tounosu, N; Yamamoto, Y, 1982)
"After confirming the presence of gastric cancer, 1-n-hexylcarbamoyl-5-fluorouracil (HCFU), a derivative of 5-fluorouracil, was given to the dogs orally as capsules at a daily dose of 5 or 10 mg/kg body weight."1.26Chemotherapeutic study on canine gastric cancer induced by N-ethyl-N'-nitro-N-nitrosoguanidine. ( Aoyagi, M; Hirashima, T; Hirota, T; Kawachi, T; Matsukura, N; Sugimura, T; Takasugi, T; Uchida, E; Ushio, K; Yoshida, S, 1980)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19908 (44.44)18.7374
1990's5 (27.78)18.2507
2000's5 (27.78)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Osterlund, P2
Orpana, A1
Elomaa, I2
Repo, H1
Joensuu, H2
Sadahiro, S1
Mitomi, T1
Noto, T1
Kumada, K1
Hiki, Y1
Yamakawa, T1
Amano, T1
Oki, S1
Otani, Y1
Oka, H1
Takahashi, T1
Takemiya, S1
Nishiyama, K1
Yamamura, T1
Tsuchiya, S1
Ogawa, N1
Akazawa, S1
Honda, T1
Sampi, K1
Nakagawa, T1
Fujiki, T1
Kanda, Y1
Futatsuki, K1
Izuno, O1
Suda, Y1
Sato, H1
Satoh, H1
Isono, K1
Onoda, S1
Okuyama, K1
Tounosu, N1
Yamamoto, Y1
Kimura, M1
Chin, F1
Kouzu, T1
Ryu, M1
Hirasawa, H1
Tokuzen, R1
Iigo, M1
Hoshi, A1
Kuretani, K1
Tsuruo, T1
Iida, H1
Naganuma, K1
Tsukagoshi, S1
Sakurai, Y1
Matsukura, N1
Aoyagi, M1
Kawachi, T1
Uchida, E1
Yoshida, S1
Hirashima, T1
Takasugi, T1
Ushio, K1
Hirota, T1
Sugimura, T1
Ikeda, M1
Teshima, K1
Noda, K1
Yamagata, S1
Sugawa, T1
Okamura, S1
Kubo, H1
Sugimoto, O1
Nakajima, H1
Yamabe, T1
Matsuda, T1
Mabuchi, K2
Kitaoka, H1
Hirata, N1
Kitaoka, U1
Sasaki, K1
Takasaka, H1
Kawasaki, H1
Matsunaga, T1
Nakagawa, N1
Shibata, K1
Yabana, T1
Yasojima, T1
Furuhata, T1
Hata, F1
Hirata, K1
Virkkunen, P1
Nagawa, H1
Muto, T1
Sunouchi, K1
Higuchi, Y1
Tsurita, G1
Watanabe, T2
Sawada, T1
Kubota, T1
Fujita, S1
Kodaira, S1
Yamamoto, T1
Josui, K1
Arisawa, Y1
Suto, A1
Ishibiki, K1
Abe, O1
Yamauchi, M1
Satta, T1
Ito, A1
Kondo, K1
Akiyama, S1
Ito, K1
Takagi, H1
Suzuki, T1
Koizumi, J1
Uchida, K1
Shiraishi, H1
Hori, M1
Miyamoto, H1
Dokiya, T1
Tominaga, J1
Kunieda, E1
Shigematsu, N1
Hashimoto, S1
Asakawa, H1
Koyama, K1
Otake, S1
Otawa, H1
Takashima, S1
Kinami, Y1
Kiriyama, M1
Tomita, F1
Ueno, K1
Miyazaki, I1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Lateral Pelvic Lymph Node Dissection After Neoadjuvant Chemo-radiation for Preoperative Enlarged Lateral Nodes in Advanced Low Rectal Cancer: a Phase III Randomized Controlled Trial[NCT02614157]51 participants (Actual)Interventional2016-05-31Terminated (stopped due to The enrollment was too low)
Total Mesorectal Excision(TME) With Lateral Lymph Node Dissection Versus TME After Neoadjuvant Chemo-radiotherapy of Lower Rectal Cancer With Suspected Local Lymph Node Metastasis[NCT03587480]250 participants (Anticipated)Interventional2018-12-17Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for carmofur and Adenocarcinoma, Basal Cell

ArticleYear
[Multicenter comparative study of the recurrence-inhibitory effect of oral fluoropyrimidine drugs in patients with colorectal cancer following curative resection].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:7

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Pr

2005
[Long-term administration of carmofur as a post-operative adjuvant chemotherapy for cervical adenocarcinoma. Cervical Adenocarcinoma Cooperative Research Association].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:12

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell;

1994
Randomized, controlled trial of lateral node dissection vs. nerve-preserving resection in patients with rectal cancer after preoperative radiotherapy.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Autonomic Nervous System; Disease-Free Survival; Female

2001
Randomized, controlled trial of lateral node dissection vs. nerve-preserving resection in patients with rectal cancer after preoperative radiotherapy.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Autonomic Nervous System; Disease-Free Survival; Female

2001
Randomized, controlled trial of lateral node dissection vs. nerve-preserving resection in patients with rectal cancer after preoperative radiotherapy.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Autonomic Nervous System; Disease-Free Survival; Female

2001
Randomized, controlled trial of lateral node dissection vs. nerve-preserving resection in patients with rectal cancer after preoperative radiotherapy.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Autonomic Nervous System; Disease-Free Survival; Female

2001

Other Studies

15 other studies available for carmofur and Adenocarcinoma, Basal Cell

ArticleYear
Raltitrexed treatment promotes systemic inflammatory reaction in patients with colorectal carcinoma.
    British journal of cancer, 2002, Sep-09, Volume: 87, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P

2002
[Combination chemotherapy of CIS-diamminedichloroplatinum (II) and fluoropyrimidine derivatives for advanced gastric cancer: a preliminary report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluo

1984
[Evaluation of the therapeutic effect of HCFU (1-hexylcarbamoyl-5-fluorouracil) on non-resectable stomach cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Agents; Drug Evaluation; Female; F

1982
Effect of 1-hexylcarbamoyl-5-fluorouracil on spontaneous mammary adenocarcinoma of mice.
    Gan, 1980, Volume: 71, Issue:5

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Drug Administration Schedule; Female; Fluorouracil;

1980
Inhibition of murine colon adenocarcinomas and Lewis lung carcinoma by 1-hexylcarbamoyl-5-fluorouracil.
    Cancer chemotherapy and pharmacology, 1980, Volume: 4, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; In Vitro Techniques

1980
Chemotherapeutic study on canine gastric cancer induced by N-ethyl-N'-nitro-N-nitrosoguanidine.
    Gan, 1980, Volume: 71, Issue:3

    Topics: Adenocarcinoma; Animals; Dogs; Fluorouracil; Humans; Male; Methylnitronitrosoguanidine; Stomach Neop

1980
[A case of multiple liver metastases showing good response by administration of carmofur alone in an aged patient with colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents; Colonic Neopla

1999
[Weekly low-dose CPT-11 and HCFU for advanced colorectal cancer on an outpatient treatment basis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:6

    Topics: Adenocarcinoma; Administration, Oral; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Pr

2000
A phase I study of raltitrexed (Tomudex) combined with carmofur in metastatic colorectal cancer.
    Oncology, 2001, Volume: 61, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; D

2001
Antitumor activity of fluoropyrimidines and thymidylate synthetase inhibition.
    Japanese journal of cancer research : Gann, 1991, Volume: 82, Issue:4

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma; Colonic Neoplasms; Enzyme Activation; Flu

1991
Subrenal capsule assay using nude mice as a predictor of the response of the gastric cancer to chemotherapy.
    Journal of surgical oncology, 1991, Volume: 47, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Fluorouracil; Huma

1991
Carmofur-induced organic mental disorders.
    The Japanese journal of psychiatry and neurology, 1990, Volume: 44, Issue:4

    Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Electroencephalography; Female; Fluorouracil; Follow-U

1990
[Combined effects of radiation and 5-FU derivatives].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:3 Pt 1

    Topics: Adenocarcinoma; Animals; Cell Division; Fluorouracil; Male; Mice; Radiotherapy Dosage; Tegafur

1986
[Evaluation of combined radiotherapy of gastric carcinoma].
    Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

1985
[Distribution of 1-hexycarbamoyl-5-fluorouracil in rats and human patients, and clinical results in patients with colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:3 Pt 1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Female; Fluorouracil; Humans; Mal

1986