carisoprodol has been researched along with Spasm in 17 studies
Carisoprodol: A centrally acting skeletal muscle relaxant whose mechanism of action is not completely understood but may be related to its sedative actions. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1202)
carisoprodol : A carbamate ester that is the mono-N-isopropyl derivative of meprobamate (which is a significant metabolite). Carisoprodol interrupts neuronal communication within the reticular formation and spinal cord, resulting in sedation and alteration in pain perception. It is used as a muscle relaxant in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm.
Spasm: An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this multicenter study was to compare the efficacy and safety of carisoprodol 250-mg tablets four times daily to 350-mg tablets four times daily and to placebo in patients with acute, painful musculoskeletal spasm of the lower back." | 9.14 | Randomized, double-blind trial of carisoprodol 250 mg compared with placebo and carisoprodol 350 mg for the treatment of low back spasm. ( Sacks, HJ; Serfer, GT; Wheeler, WJ, 2010) |
| "The objective of this placebo-controlled trial was to determine the efficacy and safety of carisoprodol (Soma, MedPointe Pharmaceuticals, Somerset, NJ, USA), a centrally acting skeletal muscle relaxant used to treat acute, painful musculoskeletal conditions, at a dosage of 250 mg three times daily and at bedtime in patients with acute, painful muscle spasm of the lower back." | 9.13 | Double-blind, placebo-controlled trial of carisoprodol 250-mg tablets in the treatment of acute lower-back spasm. ( Look, M; Ralph, L; Sacks, H; Wheeler, W, 2008) |
| "A 28-year-old woman with severe back muscle spasm took carisoprodol 2800 mg/day before and throughout an uncomplicated pregnancy and while exclusively breast-feeding her infant during the first month after birth." | 7.74 | High-dose carisoprodol during pregnancy and lactation. ( Ambrose, PJ; Briggs, GG; Nageotte, MP; Padilla, G, 2008) |
| "The purpose of this multicenter study was to compare the efficacy and safety of carisoprodol 250-mg tablets four times daily to 350-mg tablets four times daily and to placebo in patients with acute, painful musculoskeletal spasm of the lower back." | 5.14 | Randomized, double-blind trial of carisoprodol 250 mg compared with placebo and carisoprodol 350 mg for the treatment of low back spasm. ( Sacks, HJ; Serfer, GT; Wheeler, WJ, 2010) |
| "The objective of this placebo-controlled trial was to determine the efficacy and safety of carisoprodol (Soma, MedPointe Pharmaceuticals, Somerset, NJ, USA), a centrally acting skeletal muscle relaxant used to treat acute, painful musculoskeletal conditions, at a dosage of 250 mg three times daily and at bedtime in patients with acute, painful muscle spasm of the lower back." | 5.13 | Double-blind, placebo-controlled trial of carisoprodol 250-mg tablets in the treatment of acute lower-back spasm. ( Look, M; Ralph, L; Sacks, H; Wheeler, W, 2008) |
| "A 28-year-old woman with severe back muscle spasm took carisoprodol 2800 mg/day before and throughout an uncomplicated pregnancy and while exclusively breast-feeding her infant during the first month after birth." | 3.74 | High-dose carisoprodol during pregnancy and lactation. ( Ambrose, PJ; Briggs, GG; Nageotte, MP; Padilla, G, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (82.35) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Serfer, GT | 1 |
| Wheeler, WJ | 1 |
| Sacks, HJ | 1 |
| TUREK, L | 1 |
| COWAN, IC | 1 |
| MAPES, RE | 1 |
| LAWRENCE, GB | 1 |
| FORSYTH, JI | 1 |
| GREEN, EA | 2 |
| TARPLEY, EL | 1 |
| CAMPBELL, ED | 1 |
| BOUMAN, HD | 1 |
| GREADY, DM | 1 |
| TUREK, LH | 1 |
| ABRUZZI, WA | 1 |
| Ralph, L | 1 |
| Look, M | 1 |
| Wheeler, W | 1 |
| Sacks, H | 1 |
| Briggs, GG | 1 |
| Ambrose, PJ | 1 |
| Nageotte, MP | 1 |
| Padilla, G | 1 |
| Miller, AR | 1 |
| Hartmann-von Monakow, K | 1 |
| Kamperman, CL | 1 |
| Diamantis, W | 1 |
| Kletzkin, M | 1 |
3 trials available for carisoprodol and Spasm
| Article | Year |
|---|---|
Randomized, double-blind trial of carisoprodol 250 mg compared with placebo and carisoprodol 350 mg for the treatment of low back spasm.
Topics: Carisoprodol; Double-Blind Method; Humans; Lumbar Vertebrae; Muscle Relaxants, Central; Placebos; Pr | 2010 |
Double-blind, placebo-controlled trial of carisoprodol 250-mg tablets in the treatment of acute lower-back spasm.
Topics: Acute Disease; Adolescent; Adult; Aged; Carisoprodol; Disability Evaluation; Female; Humans; Low Bac | 2008 |
A comparative study of Parafon Forte tablets and soma compound in the treatment of painful skeletal muscle conditions.
Topics: Acetaminophen; Adolescent; Adult; Benzoxazoles; Carisoprodol; Chlorzoxazone; Drug Combinations; Fema | 1976 |
14 other studies available for carisoprodol and Spasm
| Article | Year |
|---|---|
Muscular spasm and pain. The use of carisoprodol (Soma) in industrial and general practice.
Topics: Carisoprodol; Disease; General Practice; Humans; Muscle Cramp; Muscle Relaxants, Central; Muscles; M | 1960 |
CARISOPRODOL IN THE MANAGEMENT OF MUSCULOSKELETAL DISORDERS. A CONTROLLED TRIAL.
Topics: Carisoprodol; Humans; Musculoskeletal Diseases; Neuritis; Osteoarthritis; Pain; Placebos; Sciatica; | 1963 |
CARISOPRODOL IN THE MANAGEMENT OF MUSCULOSKELETAL DISORDERS IN A GENERAL PRACTICE. (A CONTROLLED TRIAL).
Topics: Adolescent; Back Pain; Biomedical Research; Carisoprodol; Drug Therapy; England; General Practice; G | 1964 |
THE USE OF CARISOPRODOL FOR THE TREATMENT OF SPASTICITY IN THE MENTALLY SUBNORMAL.
Topics: Ataxia; Athetosis; Carisoprodol; Drug Therapy; Epilepsy; Hemiplegia; Humans; Intellectual Disability | 1964 |
EVALUATION OF DIAZEPAM (VALIUM) IN THE SYMPTOMATIC TREATMENT OF RHEUMATIC DISORDERS. A CONTROLLED COMPARATIVE STUDY.
Topics: Anxiety; Arthritis; Arthritis, Rheumatoid; Biomedical Research; Carisoprodol; Chlormezanone; Diazepa | 1965 |
AN ATTEMPT TO MEASURE SPASTICITY OBJECTIVELY AND THE EFFECT ON THESE MEASUREMENTS OF CARISOPRODOL.
Topics: Carisoprodol; Drug Therapy; Electrophysiology; Epilepsy; Humans; Motor Neurons; Movement Disorders; | 1965 |
THE PHYSIOLOGY OF MUSCLE SPASM AS RELATED TO LOW BACK PAIN.
Topics: Back Pain; Carisoprodol; Humans; Low Back Pain; Mephenesin; Meprobamate; Muscles; Neurophysiology; P | 1965 |
USE OF CARISOPRODOL IN SYMPTOMATIC THERAPY OF PAINFUL MUSCLE SPASM.
Topics: Adolescent; Arthritis; Arthritis, Rheumatoid; Carisoprodol; Drug Therapy; Geriatrics; Myositis; Spas | 1965 |
Carisoprodol for muscular spasm and pain seen in industrial and general practice.
Topics: Carisoprodol; General Practice; Humans; Muscle Cramp; Muscle Relaxants, Central; Pain; Spasm | 1961 |
A CONTROLLED EVALUATION OF CHLORPHENESIN CARBAMATE IN PAINFUL MUSCULOSKELETAL SYNDROMES.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Carbamates; Carisoprodol; Chlorphenesin; Fibromy | 1964 |
High-dose carisoprodol during pregnancy and lactation.
Topics: Adult; Back Pain; Biological Transport; Breast Feeding; Carisoprodol; Female; Humans; Infant, Newbor | 2008 |
[Therapy of spastic syndromes].
Topics: Carisoprodol; Chlordiazepoxide; Chlormezanone; Chlorzoxazone; Curare; Diazepam; Guaifenesin; Humans; | 1969 |
A drug to relieve muscle spasm.
Topics: Adult; Aged; Carisoprodol; Humans; Male; Middle Aged; Muscle Cramp; Spasm | 1966 |
Evaluation of muscle relaxant drugs by head-drop and by decerebrate rigidity.
Topics: Animals; Carbamates; Carisoprodol; Cats; Chlordiazepoxide; Diazepam; Electromyography; Gallamine Tri | 1966 |