Page last updated: 2024-10-24

carisoprodol and Serotonin Syndrome

carisoprodol has been researched along with Serotonin Syndrome in 2 studies

Carisoprodol: A centrally acting skeletal muscle relaxant whose mechanism of action is not completely understood but may be related to its sedative actions. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1202)
carisoprodol : A carbamate ester that is the mono-N-isopropyl derivative of meprobamate (which is a significant metabolite). Carisoprodol interrupts neuronal communication within the reticular formation and spinal cord, resulting in sedation and alteration in pain perception. It is used as a muscle relaxant in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm.

Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lamberg, JJ1
Gordin, VN1
Bramness, JG1
Mørland, J1
Sørlid, HK1
Rudberg, N1
Jacobsen, D1

Other Studies

2 other studies available for carisoprodol and Serotonin Syndrome

ArticleYear
Serotonin syndrome in a patient with chronic pain polypharmacy.
    Pain medicine (Malden, Mass.), 2014, Volume: 15, Issue:8

    Topics: Adult; Amitriptyline; Anti-Allergic Agents; Antidepressive Agents; Carisoprodol; Cetirizine; Chronic

2014
Carisoprodol intoxications and serotonergic features.
    Clinical toxicology (Philadelphia, Pa.), 2005, Volume: 43, Issue:1

    Topics: Adult; Carisoprodol; Diagnosis, Differential; Drug Overdose; Female; Humans; Muscle Relaxants, Centr

2005