carisoprodol has been researched along with Low Back Ache in 4 studies
Carisoprodol: A centrally acting skeletal muscle relaxant whose mechanism of action is not completely understood but may be related to its sedative actions. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1202)
carisoprodol : A carbamate ester that is the mono-N-isopropyl derivative of meprobamate (which is a significant metabolite). Carisoprodol interrupts neuronal communication within the reticular formation and spinal cord, resulting in sedation and alteration in pain perception. It is used as a muscle relaxant in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this placebo-controlled trial was to determine the efficacy and safety of carisoprodol (Soma, MedPointe Pharmaceuticals, Somerset, NJ, USA), a centrally acting skeletal muscle relaxant used to treat acute, painful musculoskeletal conditions, at a dosage of 250 mg three times daily and at bedtime in patients with acute, painful muscle spasm of the lower back." | 9.13 | Double-blind, placebo-controlled trial of carisoprodol 250-mg tablets in the treatment of acute lower-back spasm. ( Look, M; Ralph, L; Sacks, H; Wheeler, W, 2008) |
| "Cyclobenzaprine hydrochloride has the most recent and largest clinical trials demonstrating its benefit, but carisoprodol and metaxalone also appear to be effective." | 6.42 | Commonly used muscle relaxant therapies for acute low back pain: a review of carisoprodol, cyclobenzaprine hydrochloride, and metaxalone. ( Toth, PP; Urtis, J, 2004) |
| "The objective of this placebo-controlled trial was to determine the efficacy and safety of carisoprodol (Soma, MedPointe Pharmaceuticals, Somerset, NJ, USA), a centrally acting skeletal muscle relaxant used to treat acute, painful musculoskeletal conditions, at a dosage of 250 mg three times daily and at bedtime in patients with acute, painful muscle spasm of the lower back." | 5.13 | Double-blind, placebo-controlled trial of carisoprodol 250-mg tablets in the treatment of acute lower-back spasm. ( Look, M; Ralph, L; Sacks, H; Wheeler, W, 2008) |
| "Cyclobenzaprine hydrochloride has the most recent and largest clinical trials demonstrating its benefit, but carisoprodol and metaxalone also appear to be effective." | 2.42 | Commonly used muscle relaxant therapies for acute low back pain: a review of carisoprodol, cyclobenzaprine hydrochloride, and metaxalone. ( Toth, PP; Urtis, J, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BOUMAN, HD | 1 |
| Toth, PP | 1 |
| Urtis, J | 1 |
| Ralph, L | 1 |
| Look, M | 1 |
| Wheeler, W | 1 |
| Sacks, H | 1 |
| Oland, G | 1 |
| Skjelbred, O | 1 |
| Vik, Ø | 1 |
| Karlsen, M | 1 |
1 review available for carisoprodol and Low Back Ache
| Article | Year |
|---|---|
Commonly used muscle relaxant therapies for acute low back pain: a review of carisoprodol, cyclobenzaprine hydrochloride, and metaxalone.
Topics: Amitriptyline; Carisoprodol; Humans; Low Back Pain; Muscle Relaxants, Central; Oxazolidinones; Rando | 2004 |
1 trial available for carisoprodol and Low Back Ache
| Article | Year |
|---|---|
Double-blind, placebo-controlled trial of carisoprodol 250-mg tablets in the treatment of acute lower-back spasm.
Topics: Acute Disease; Adolescent; Adult; Aged; Carisoprodol; Disability Evaluation; Female; Humans; Low Bac | 2008 |
2 other studies available for carisoprodol and Low Back Ache
| Article | Year |
|---|---|
THE PHYSIOLOGY OF MUSCLE SPASM AS RELATED TO LOW BACK PAIN.
Topics: Back Pain; Carisoprodol; Humans; Low Back Pain; Mephenesin; Meprobamate; Muscles; Neurophysiology; P | 1965 |
[Guidelines concerning acute low back pain].
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Carisoprodol; Humans; Low Back Pain; Muscle Rel | 2002 |