carisoprodol has been researched along with Drug Withdrawal Symptoms in 12 studies
Carisoprodol: A centrally acting skeletal muscle relaxant whose mechanism of action is not completely understood but may be related to its sedative actions. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1202)
carisoprodol : A carbamate ester that is the mono-N-isopropyl derivative of meprobamate (which is a significant metabolite). Carisoprodol interrupts neuronal communication within the reticular formation and spinal cord, resulting in sedation and alteration in pain perception. It is used as a muscle relaxant in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carisoprodol has been classified as a controlled substance in several states in the US and restrictions on the use of the drug have been imposed in some European countries." | 2.46 | Carisoprodol: abuse potential and withdrawal syndrome. ( Burke, RS; Reeves, RR, 2010) |
| "Treatment with carisoprodol and phenobarbital provided additional benefit and can be considered in cases of severe carisoprodol withdrawal." | 1.46 | Severe Carisoprodol Withdrawal After a 14-Year Addiction and Acute Overdose. ( Benowitz, NL; Horng, H; Smollin, CG; Vo, KT, 2017) |
| "Carisoprodol treatment resulted in tolerance and antagonist-precipitated withdrawal, suggesting it may have an addiction potential similar to that of other long-acting benzodiazepine or barbiturate compounds." | 1.38 | Carisoprodol tolerance and precipitated withdrawal. ( Carbonaro, T; Forster, MJ; Gatch, MB; Nguyen, JD, 2012) |
| "Carisoprodol is a centrally acting muscle relaxant used in the treatment of various musculoskeletal disorders whose main metabolite, meprobamate, is a controlled substance in the United States due to its sedative properties and potential for abuse." | 1.36 | Carisoprodol withdrawal after internet purchase. ( Agrwal, N; Eleid, MF; Goodman, BP; Krahn, LE, 2010) |
| "Carisoprodol is a commonly used centrally acting muscle relaxant." | 1.34 | Is the frequency of carisoprodol withdrawal syndrome increasing? ( Hammer, JS; Pendarvis, RO; Reeves, RR, 2007) |
| "Carisoprodol is a commonly used skeletal muscle relaxant with potential for abuse because of its active metabolite, meprobamate, and several reports have suggested that patients abruptly stopping intake of carisoprodol may have a withdrawal syndrome." | 1.32 | Somatic dysfunction during carisoprodol cessation: evidence for a carisoprodol withdrawal syndrome. ( Parker, JD; Reeves, RR, 2003) |
| "Carisoprodol (Soma) is a noncontrolled, skeletal-muscle relaxant whose active metabolite is meprobamate." | 1.30 | Carisoprodol: a drug of continuing abuse. ( Carter, OS; Pinkofsky, HB; Reeves, RR, 1997) |
| "Carisoprodol (Somadril) was gradually withdrawn for a fortnight in nine male prisoners who had been taking daily doses of from 700 to 2,100 mg for at least nine months." | 1.28 | [Dependence on carisoprodol (Somadril)? A prospective withdrawal study among prisoners]. ( Gadeholt, G; Korsmo, G; Wyller, TB, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vo, KT | 1 |
| Horng, H | 1 |
| Smollin, CG | 1 |
| Benowitz, NL | 1 |
| Reeves, RR | 5 |
| Burke, RS | 1 |
| Eleid, MF | 1 |
| Krahn, LE | 1 |
| Agrwal, N | 1 |
| Goodman, BP | 1 |
| Gatch, MB | 1 |
| Nguyen, JD | 1 |
| Carbonaro, T | 1 |
| Forster, MJ | 1 |
| Parker, JD | 1 |
| Beddingfield, JJ | 1 |
| Mack, JE | 1 |
| Rohatgi, G | 1 |
| Rissmiller, DJ | 1 |
| Gorman, JM | 1 |
| Hammer, JS | 1 |
| Pendarvis, RO | 1 |
| Littrell, RA | 1 |
| Sage, T | 1 |
| Miller, W | 1 |
| Pinkofsky, HB | 1 |
| Carter, OS | 1 |
| Morse, RM | 1 |
| Chua, L | 1 |
| Wyller, TB | 1 |
| Korsmo, G | 1 |
| Gadeholt, G | 1 |
1 review available for carisoprodol and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Carisoprodol: abuse potential and withdrawal syndrome.
Topics: Anxiety; Carisoprodol; Hallucinations; Humans; Hypnotics and Sedatives; Muscle Relaxants, Central; S | 2010 |
11 other studies available for carisoprodol and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Severe Carisoprodol Withdrawal After a 14-Year Addiction and Acute Overdose.
Topics: Adult; Carisoprodol; Dexmedetomidine; Drug Overdose; Fentanyl; Haloperidol; Humans; Hypnotics and Se | 2017 |
Carisoprodol withdrawal after internet purchase.
Topics: Carisoprodol; Humans; Internet; Male; Meprobamate; Middle Aged; Muscle Relaxants, Central; Substance | 2010 |
Carisoprodol tolerance and precipitated withdrawal.
Topics: Animals; Bemegride; Carisoprodol; Central Nervous System Stimulants; Dose-Response Relationship, Dru | 2012 |
Somatic dysfunction during carisoprodol cessation: evidence for a carisoprodol withdrawal syndrome.
Topics: Adult; Carisoprodol; Female; Humans; Male; Muscle Relaxants, Central; Somatosensory Disorders; Subst | 2003 |
Carisoprodol withdrawal syndrome.
Topics: Adult; Carisoprodol; Humans; Male; Substance Withdrawal Syndrome | 2004 |
Treatment of carisoprodol dependence: a case report.
Topics: Carisoprodol; Cognitive Behavioral Therapy; Humans; Male; Middle Aged; Muscle Relaxants, Central; Su | 2005 |
Is the frequency of carisoprodol withdrawal syndrome increasing?
Topics: Adult; Anxiety; Carisoprodol; Female; Hallucinations; Humans; Meprobamate; Muscle Relaxants, Central | 2007 |
Meprobamate dependence secondary to carisoprodol (Soma) use.
Topics: Adult; Biotransformation; Carisoprodol; Female; Humans; Meprobamate; Metabolic Clearance Rate; Neuro | 1993 |
Carisoprodol: a drug of continuing abuse.
Topics: Adult; Carisoprodol; Drug and Narcotic Control; Drug Prescriptions; Female; Humans; Male; Muscle Rel | 1997 |
Carisoprodol dependence: a case report.
Topics: Adult; Carisoprodol; Female; Humans; Substance Withdrawal Syndrome; Substance-Related Disorders | 1978 |
[Dependence on carisoprodol (Somadril)? A prospective withdrawal study among prisoners].
Topics: Adult; Carisoprodol; Drug Evaluation; Humans; Male; Middle Aged; Norway; Prisoners; Prospective Stud | 1991 |