Page last updated: 2024-09-04

cariporide and Disease Models, Animal

cariporide has been researched along with Disease Models, Animal in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's20 (68.97)29.6817
2010's9 (31.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baartscheer, A; Buchholtz, N; Coronel, R; Eerbeek, O; Hollmann, MW; Nederlof, R; Schumacher, C; Uthman, L; Weber, NC; Zuurbier, CJ1
Bai, H; Chen, J; Hou, H; Hu, D; Tao, K; Yang, X; Zhou, Q1
Bai, H; Cai, W; Dong, M; Han, J; Hu, D; Li, J; Liu, J; Wang, Y; Xu, Y; Yang, X; Zhou, Q; Zhu, X1
Ashrafpour, H; Cahoon, NJ; Forrest, CR; Huang, N; Jindal, K; Lipa, JE; McAllister, SE; Moses, MA; Neligan, PC; Pang, CY1
Ayoub, IM; Gazmuri, RJ; Radhakrishnan, J1
Ayoub, IM; Gazmuri, RJ; Kolarova, JD; Radhakrishnan, J1
Allen, BS; Buckberg, GD; Hristov, N; Liakopoulos, OJ; Triana, J; Trummer, G1
Arbeláez, LF; Fantinelli, J; Mosca, SM; Nuñez, IP1
Akture, E; Budoff, GE; Cengiz, P; Ferrazzano, P; Hutchinson, E; Kendigelen, P; Lee, J; Meyerand, E; Song, C; Sun, D; Uluc, K; Zhang, L1
Anzawa, R; Feuvray, D; Nagoshi, T; Seki, S; Taniguchi, I; Yoshimura, M1
Anderson, SE; Chen, YJ; Lam, TI; O'Donnell, ME; Taylor, KC; Walton, JH1
Sykes, J; Thompson, K; Thompson, RT; Wisenberg, G2
Cropper, JR; Hicks, M; Macdonald, PS; Ryan, JB1
Buckberg, GD; Castellá, M; Ignarro, LJ; Saleh, S; Tan, Z1
Dowdy, KB; Escobar, GP; Hendrick, JW; McLean, JE; Mingoia, JT; Mukherjee, R; Sample, JA; Spinale, FG; Stroud, RE; Yarbrough, WM1
Curtis, LJ; Rabkin, DG; Spotnitz, HM; Weinberg, AD1
Davies, JE; Digerness, SB; Goldberg, SP; Holman, WL; Justice, RK; Katholi, CR; Killingsworth, CR; Zaragoza, C1
Mentzer, RM1
Bartels, C; Bechtel, JF; Eichler, W; Hernandez, M; Klotz, KF; Sievers, HH; Toerber, K; Weidtmann, B1
Carranza, VB; Ennis, IL; Escudero, EM; Garciarena, CD; Pinilla, OA; Tufare, AL1
Brillault, J; Foroutan, S; Lam, TI; O'Donnell, ME; Rutkowsky, JM1
Buerke, M; Buerke, U; Carter, JM; Dahm, M; Makowski, J; Niemann, B; Prondzinsky, R; Pruefer, D; Rohrbach, S; Russ, M; Schlitt, A; Schulze, C; Vahl, CF; Werdan, K1
Aihara, K; Hisa, H; Kimura, T; Kogi, K; Mizuno, Y; Nagai, A; Sasamori, J; Sato, T; Satoh, S; Takahashi, A; Yamaguchi, F; Yoneyama, F; Yoneyama, S1
Allen, TJ; Cooper, ME; Farrelly, CA; Gilbert, RE; Hannan, KM; Jandeleit-Dahm, K; Little, PJ; Rumble, JR1
Altemose, GT; Miller, JM; Olgin, JE; Weksler, J; Zipes, DP1
Ayoub, IM; Gazmuri, RJ; Hoffner, E; Kolarova, JD1
Ellingsen, O; Falck, G; Loennechen, JP; Wisløff, U1
Engelhardt, S; Hein, L; Keller, U; Klämbt, K; Lohse, MJ1

Other Studies

29 other study(ies) available for cariporide and Disease Models, Animal

ArticleYear
Delayed ischaemic contracture onset by empagliflozin associates with NHE1 inhibition and is dependent on insulin in isolated mouse hearts.
    Cardiovascular research, 2019, Aug-01, Volume: 115, Issue:10

    Topics: Animals; Benzhydryl Compounds; Disease Models, Animal; Glucosides; Guanidines; Insulin; Isolated Heart Preparation; Male; Mice, Inbred C57BL; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Signal Transduction; Sodium-Glucose Transporter 2 Inhibitors; Sodium-Hydrogen Exchanger 1; Sulfones; Time Factors

2019
Inhibition of Na+/H+ exchanger 1 by cariporide reduces burn-induced intestinal barrier breakdown.
    Burns : journal of the International Society for Burn Injuries, 2013, Volume: 39, Issue:8

    Topics: Animals; Anti-Arrhythmia Agents; Burns; Cation Transport Proteins; Disease Models, Animal; Guanidines; Intestines; Mice; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Permeability; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Sulfones

2013
Inhibition of Na+/H+ exchanger 1 by cariporide alleviates burn-induced multiple organ injury.
    The Journal of surgical research, 2013, Volume: 185, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Burns; Disease Models, Animal; Gene Expression; Guanidines; Intestines; Kidney; Lung; Male; Multiple Organ Failure; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Sulfones

2013
Na+/H+ exchange inhibitor cariporide attenuates skeletal muscle infarction when administered before ischemia or reperfusion.
    Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 106, Issue:1

    Topics: Adenosine Triphosphate; Animals; Calcium; Castration; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Guanidines; Infarction; Injections, Intravenous; Mitochondria, Muscle; Muscle, Skeletal; Necrosis; Neutrophil Infiltration; Neutrophils; Peroxidase; Reperfusion Injury; Sodium-Hydrogen Exchangers; Sulfones; Surgical Flaps; Swine; Time Factors

2009
Activation of caspase-3 may not contribute to postresuscitation myocardial dysfunction.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Apoptosis; Caspase 3; Caspase Inhibitors; Disease Models, Animal; DNA Fragmentation; Guanidines; Heart; Heart Massage; Male; Myocardial Contraction; Myocardium; Oligopeptides; Rats; Rats, Sprague-Dawley; Resuscitation; Sodium-Hydrogen Exchangers; Sulfones; Ventricular Dysfunction, Left; Ventricular Fibrillation

2009
AVE4454B--a novel sodium-hydrogen exchanger isoform-1 inhibitor--compared less effective than cariporide for resuscitation from cardiac arrest.
    Translational research : the journal of laboratory and clinical medicine, 2011, Volume: 157, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Guanidines; Heart Arrest; Inhibitory Concentration 50; Male; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Sulfones; Ventricular Fibrillation; Ventricular Function, Left

2011
Resuscitation after prolonged cardiac arrest: effects of cardiopulmonary bypass and sodium-hydrogen exchange inhibition on myocardial and neurological recovery.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2011, Volume: 40, Issue:4

    Topics: Animals; Cardiopulmonary Bypass; Cardiopulmonary Resuscitation; Combined Modality Therapy; Disease Models, Animal; Guanidines; Heart Arrest; Hemodynamics; Myocardial Reperfusion Injury; Nervous System Diseases; Seizures; Sodium-Hydrogen Exchangers; Sulfones; Sus scrofa; Treatment Outcome

2011
Mitochondrial KATP channels participate in the limitation of infarct size by cariporide.
    Naunyn-Schmiedeberg's archives of pharmacology, 2011, Volume: 383, Issue:6

    Topics: Animals; Calcium; Cardiotonic Agents; Decanoic Acids; Diazoxide; Disease Models, Animal; Guanidines; Hydroxy Acids; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Myocardial Reperfusion Injury; Potassium Channels; Protein Kinase C; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Sulfones

2011
Chronic neurological deficits in mice after perinatal hypoxia and ischemia correlate with hemispheric tissue loss and white matter injury detected by MRI.
    Developmental neuroscience, 2011, Volume: 33, Issue:3-4

    Topics: Animals; Animals, Newborn; Brain; Child; Cognition Disorders; Disease Models, Animal; Guanidines; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Infant, Premature; Learning; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Neuropsychological Tests; Random Allocation; Sodium-Hydrogen Exchangers; Sulfones

2011
The role of Na+/H+ exchanger in Ca2+ overload and ischemic myocardial damage in hearts from type 2 diabetic db/db mice.
    Cardiovascular diabetology, 2012, Apr-11, Volume: 11

    Topics: Animals; Calcium; Diabetes Mellitus, Type 2; Disease Models, Animal; Guanidines; Male; Mice; Mice, Mutant Strains; Myocardial Reperfusion Injury; Sodium-Hydrogen Exchangers; Sulfones; Ventricular Dysfunction, Left

2012
Intravenous HOE-642 reduces brain edema and Na uptake in the rat permanent middle cerebral artery occlusion model of stroke: evidence for participation of the blood-brain barrier Na/H exchanger.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2013, Volume: 33, Issue:2

    Topics: Administration, Intravenous; Animals; Anti-Arrhythmia Agents; Blood-Brain Barrier; Brain Edema; Brain Infarction; Disease Models, Animal; Guanidines; Infarction, Middle Cerebral Artery; Magnetic Resonance Spectroscopy; Male; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers; Stroke; Sulfones

2013
MRI/MRS evaluation of cariporide in a canine long-term model of reperfused ischemic insults. Magnetic resonance imaging/magnetic resonance spectroscopy.
    Journal of magnetic resonance imaging : JMRI, 2003, Volume: 17, Issue:1

    Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Dogs; Female; Guanidines; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Myocardial Ischemia; Reperfusion; Sulfones; Time Factors

2003
Long-term magnetic resonance imaging/spectroscopy study of cariporide in a canine cardiac ischemia/reperfusion model.
    Journal of cardiovascular pharmacology, 2003, Volume: 41, Issue:4

    Topics: Animals; Disease Models, Animal; Dogs; Female; Guanidines; Hemodynamics; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Myocardial Reperfusion Injury; Sulfones

2003
Cardioprotection by cariporide after prolonged hypothermic storage of the isolated working rat heart.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2003, Volume: 22, Issue:8

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Guanidines; Hypothermia, Induced; Male; Organ Preservation; Rats; Rats, Wistar; Reperfusion Injury; Sulfones; Time Factors

2003
A new role for cardioplegic buffering: should acidosis or calcium accumulation be counteracted to salvage jeopardized hearts?
    The Journal of thoracic and cardiovascular surgery, 2003, Volume: 126, Issue:5

    Topics: Acidosis; Animals; Buffers; Calcium; Cardioplegic Solutions; Creatine Kinase; Creatine Kinase, MB Form; Disease Models, Animal; Female; Guanidines; Heart Arrest, Induced; Hydrogen-Ion Concentration; Ischemic Preconditioning, Myocardial; Isoenzymes; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Random Allocation; Reference Values; Sensitivity and Specificity; Sodium-Hydrogen Exchangers; Sulfones; Swine; Ventricular Function, Left

2003
Direct inhibition of the sodium/hydrogen exchanger after prolonged regional ischemia improves contractility on reperfusion independent of myocardial viability.
    The Journal of thoracic and cardiovascular surgery, 2003, Volume: 126, Issue:5

    Topics: Animals; Biopsy, Needle; Disease Models, Animal; Female; Guanidines; Heart Function Tests; Hemodynamics; Infusions, Intravenous; Male; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Random Allocation; Recovery of Function; Reference Values; Sensitivity and Specificity; Sodium-Hydrogen Exchangers; Sulfones; Swine; Ventricular Function, Left

2003
Na+/H+ exchange inhibition and antioxidants lack additive protective effects after reperfusion injury in the working heterotopic rat heart isograft.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2005, Volume: 24, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Cardiac Volume; Compliance; Disease Models, Animal; Drug Therapy, Combination; Guanidines; Heart Transplantation; Organ Size; Probucol; Rats; Rats, Inbred Lew; Reperfusion Injury; Sodium-Hydrogen Exchangers; Sulfones; Transplantation, Heterotopic; Transplantation, Isogeneic

2005
Multiple treatment approach to limit cardiac ischemia-reperfusion injury.
    The Annals of thoracic surgery, 2005, Volume: 80, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Cardiac Surgical Procedures; Combined Modality Therapy; Diazoxide; Disease Models, Animal; Drug Therapy, Combination; Female; Guanidines; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Recovery of Function; Reference Values; Sulfones; Swine; Treatment Outcome; Vasodilator Agents; Ventricular Dysfunction, Left

2005
Invited commentary.
    The Annals of thoracic surgery, 2005, Volume: 80, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Cardiac Surgical Procedures; Combined Modality Therapy; Diazoxide; Disease Models, Animal; Drug Therapy, Combination; Guanidines; Myocardial Infarction; Myocardial Reperfusion Injury; Sulfones; Swine; Treatment Outcome; Vasodilator Agents

2005
The Na+/H+ exchange inhibitor cariporide is washed out of the myocardium by crystalloid cardioplegia.
    The Thoracic and cardiovascular surgeon, 2006, Volume: 54, Issue:5

    Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiopulmonary Bypass; Coronary Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Guanidines; Heart Arrest, Induced; Heart Rate; Myocardial Contraction; Myocardial Ischemia; Myocardium; Postoperative Complications; Potassium Compounds; Research Design; Sodium-Hydrogen Exchangers; Stroke Volume; Sulfones; Swine; Troponin T; Ventricular Function, Left

2006
[Echocardiographic analysis of the effect of different Na+/H+ exchanger inhibitors on left ventricular structure and function in spontaneously hypertensive rats].
    Medicina, 2006, Volume: 66, Issue:5

    Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Cardiac Volume; Disease Models, Animal; Guanidines; Heart; Heart Ventricles; Hypertrophy, Left Ventricular; Male; Myocardial Contraction; Rats; Rats, Inbred SHR; Sodium-Hydrogen Exchangers; Stimulation, Chemical; Sulfones; Ultrasonography; Ventricular Function, Left

2006
Hypoxia effects on cell volume and ion uptake of cerebral microvascular endothelial cells.
    American journal of physiology. Cell physiology, 2008, Volume: 294, Issue:1

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Bumetanide; Cattle; Cell Hypoxia; Cell Size; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Extracellular Fluid; Glucose; Guanidines; Infarction, Middle Cerebral Artery; Intracellular Fluid; Microcirculation; Potassium; Rats; Sodium; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters; Sulfones; Time Factors; Vasopressins

2008
Sodium/hydrogen exchange inhibition with cariporide reduces leukocyte adhesion via P-selectin suppression during inflammation.
    British journal of pharmacology, 2008, Volume: 153, Issue:8

    Topics: Animals; Calcium; Cell Adhesion; Disease Models, Animal; Guanidines; Inflammation; Leukocyte Rolling; Leukocytes; Male; Mesentery; Microcirculation; Microscopy; P-Selectin; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sodium-Hydrogen Exchangers; Sulfones

2008
Cardioprotective effect of TY-12533, a novel Na(+)/H(+) exchange inhibitor, on ischemia/reperfusion injury.
    European journal of pharmacology, 2000, Sep-15, Volume: 404, Issue:1-2

    Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiotonic Agents; Disease Models, Animal; Guanidines; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Pyridines; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Sulfones

2000
Diabetes-induced vascular hypertrophy is accompanied by activation of Na(+)-H(+) exchange and prevented by Na(+)-H(+) exchange inhibition.
    Circulation research, 2000, Dec-08, Volume: 87, Issue:12

    Topics: Animals; Anti-Arrhythmia Agents; Blood Vessels; Diabetes Mellitus, Experimental; Disease Models, Animal; Guanidines; Hydrogen-Ion Concentration; Hypertrophy; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Streptozocin; Sulfones

2000
Inhibition of the Na(+)/H(+) exchanger delays the development of rapid pacing-induced atrial contractile dysfunction.
    Circulation, 2001, Feb-06, Volume: 103, Issue:5

    Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Function, Left; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Guanidines; Myocardial Contraction; Protein Isoforms; Sodium-Hydrogen Exchangers; Sulfones

2001
Successful ventricular defibrillation by the selective sodium-hydrogen exchanger isoform-1 inhibitor cariporide.
    Circulation, 2001, Jul-10, Volume: 104, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiopulmonary Resuscitation; Disease Models, Animal; Electric Countershock; Guanidines; Heart Ventricles; In Vitro Techniques; Lactic Acid; Rats; Regression Analysis; Sodium-Hydrogen Exchangers; Sulfones; Survival Rate; Ventricular Fibrillation; Ventricular Premature Complexes

2001
Effects of cariporide and losartan on hypertrophy, calcium transients, contractility, and gene expression in congestive heart failure.
    Circulation, 2002, Mar-19, Volume: 105, Issue:11

    Topics: Angiotensins; Animals; Anti-Arrhythmia Agents; Calcium Signaling; Cardiomegaly; Cell Separation; Cell Size; Disease Models, Animal; Echocardiography; Electric Stimulation; Female; Gene Expression; Guanidines; Heart Failure; In Vitro Techniques; Losartan; Myocardial Contraction; Myocardial Infarction; Myocardium; Rats; Rats, Sprague-Dawley; Sulfones; Ventricular Remodeling

2002
Inhibition of Na(+)-H(+) exchange prevents hypertrophy, fibrosis, and heart failure in beta(1)-adrenergic receptor transgenic mice.
    Circulation research, 2002, Apr-19, Volume: 90, Issue:7

    Topics: Administration, Oral; Animals; Blotting, Western; Body Weight; Cardiomegaly; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Fibrosis; Gene Expression; Guanidines; Heart Failure; Humans; Mice; Mice, Transgenic; Myocardial Contraction; Myocardium; Organ Size; Receptors, Adrenergic, beta-1; RNA, Messenger; Sodium-Hydrogen Exchangers; Sulfones; Ventricular Dysfunction, Left

2002