cardiovascular-agents and Rheumatic-Diseases

Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Asthma; Cardiovascular Agents; Central Nervous System Depressants; Diuretics; Drug Therapy; Expectorants; Hormones; Humans; Hypolipidemic Agents; Metabolism; Parasympatholytics; Pharmacology; Radiation-Sensitizing Agents; Rheumatic Diseases

No studies have been conducted on rational drug use among children in Uzbekistan. This study aimed to analyze drug uses based on pharmaco-epidemiologic (PE) data from Regional Children's Multi-Profile Medical Centre (RCMPMC) in Andijan, Uzbekistan. Our study assessed drug usage in children with cardiovascular (CV) diseases, without intervening in the treatment processes or in the course of the diseases.. Subjects were 853 children aged 0 to 180 months (median age, 60 months; inter-quartile range, 24-108 months) who were hospitalized in the department of Cardiology and Rheumatology in RCMPMC from January to December, 2013 and were prescribed one or more drugs during hospitalization. Drugs used for a different disease or medical condition, given in a different way and/or given in a different dose were analyzed and considered to be irrational drugs.. The most commonly used medications among 10 drug groups prescribed by the doctors of RCMPMC were as follows: anti-arrhythmic (aspartic acid - 54.0 %), glycosides (digoxin - 44.0 %), diuretics (furosemide - 34.0 %), vitamins (ascorbic acid - 25.0 %), steroid anti-inflammatory drugs (prednisolone - 19.0 %), non-steroid anti-inflammatory drugs (diclofenac - 17.0 %), antibiotics (amoxicillin - 16.0 %), non-steroid anabolic drugs (potassium orotas - 14.0 %) and angiotensin-converting enzyme inhibitors (captopril - 11.0 %).. The study found that irrational drug schemes were quite frequent among pediatric CV patients and they are most frequent in children aged 2-3 years and younger.

Topics: Antirheumatic Agents; Cardiovascular Agents; Cardiovascular Diseases; Child; Child, Preschool; Cross-Sectional Studies; Developing Countries; Female; Heart Defects, Congenital; Hospitals, District; Hospitals, Pediatric; Humans; Inappropriate Prescribing; Infant; Infant, Newborn; Male; Practice Patterns, Physicians'; Rheumatic Diseases; Rheumatic Heart Disease; Uzbekistan

Topics: Anti-Inflammatory Agents; Autoimmune Diseases; Autoimmunity; Cardiovascular Agents; Cardiovascular Diseases; Drug Design; Humans; Immunomodulation; Molecular Targeted Therapy; Rheumatic Diseases; Rheumatoid Vasculitis; Systemic Vasculitis

Topics: Brazil; Cardiac Surgical Procedures; Cardiovascular Agents; Chagas Disease; Heart Failure; Humans; Marketing; Placebos; Rheumatic Diseases

Topics: Aminopyrine; Cardiovascular Agents; Muscle Relaxants, Central; Muscular Diseases; Osteochondritis; Rheumatic Diseases; Spondylitis; Tendons

Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Cardiovascular Agents; Humans; Muscle Relaxants, Central; Prednisolone; Rheumatic Diseases; Rheumatology

Topics: Cardiovascular Agents; Fibromyalgia; Humans; Joint Diseases; Rheumatic Diseases; Tranquilizing Agents

Topics: Cardiovascular Agents; Ergot Alkaloids; Oxytocics; Rheumatic Diseases

Topics: Aminopyrine; Aspirin; Cardiovascular Agents; Carisoprodol; Humans; Muscle Relaxants, Central; Rheumatic Diseases; Rheumatology

Topics: Cardiovascular Agents; Chlorzoxazone; Fibromyalgia; Referral and Consultation; Rheumatic Diseases; Zoxazolamine

Topics: Antirheumatic Agents; Cardiovascular Agents; Glucose; Humans; Rheumatic Diseases; Sodium Salicylate

Topics: Aminobenzoates; Anesthetics, Local; Cardiovascular Agents; Leucine; para-Aminobenzoates; Rheumatic Diseases

Topics: Cardiovascular Agents; Cortisone; Hexamethonium; Hypotension; Muscle Relaxants, Central; Rheumatic Diseases

Topics: Analgesics; Anesthetics, Local; Cardiovascular Agents; Rheumatic Diseases