cardamonin has been researched along with Sjogren-s-Syndrome* in 1 studies
1 trial(s) available for cardamonin and Sjogren-s-Syndrome
Article | Year |
---|---|
Cardamonin inhibits pro-inflammatory cytokine production and suppresses NO pathway in PBMCs from patients with primary Sjögren's syndrome.
Primary Sjögren's syndrome (pSS) is a systemic autoimmune disorder with a complex pathophysiology primarily affecting exocrine glands, leading to compromised secretory function. Recent studies imply that many inflammatory mediators, such as pro-inflammatory cytokines and nitric oxide, are critical in the development and perpetuation of pSS systemic manifestations. In the current study, we aimed to investigate the ex vivo immunomodulatory effect of cardamonin (C Topics: Adult; Chalcones; Female; Humans; Inflammation; Interleukin-6; Leukocytes, Mononuclear; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type II; Sjogren's Syndrome; Tumor Necrosis Factor-alpha | 2018 |