Page last updated: 2024-08-17

carbostyril and Metastase

carbostyril has been researched along with Metastase in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (21.21)29.6817
2010's23 (69.70)24.3611
2020's3 (9.09)2.80

Authors

AuthorsStudies
Aggarwal, R; Brose, M; Chau, NG; Cohen, EEW; Gualberto, A; Guenette, JP; Hanna, GJ; Ho, AL; Metcalf, R; Pérez-Ruiz, E; Razaq, M; Sayehli, CM; Scholz, C; Wilhelm, C; Wong, DJ1
Choi, HY; Gualberto, A; Jeong, BC; Kwon, GY; Lee, HW; Park, SH; Sa, JK; Scholz, C; Sung, HH1
Dean, DC; Duan, Z; Hornicek, FJ; Nelson, SD; Thanindratarn, P1
Dillon, PM; Douvas, MG; Fracasso, PM; Horton, BJ; Moskaluk, CA; Petroni, GR; Thomas, CY; Varhegyi, N; Zaja-Milatovic, S1
Choi, YJ; Kim, BS; Kim, HG; Kim, HS; Kim, KH; Lee, HJ; Lee, HY; Lee, JL; Lee, KH; Park, KH; Park, SH; Shin, DY; Song, HS1
Arun, B; Buzdar, AU; Hortobagyi, GN; Moulder, SL; Murray, JL; Murthy, RK; Shroff, GS; Stalzer, CJ; Szklaruk, J; Valero, V; Yam, C; Yang, W1
Banik, P; Bharti, R; Chakraborty, S; Das, SK; Dey, G; Dey, KK; Emdad, L; Fisher, PB; Ghosh, SK; Kundu, SC; Mandal, M; Naskar, D; Pal, I; Rajesh, Y1
Adil, MS; Alwhaibi, A; Artham, S; Somanath, PR; Verma, A1
Armstrong, AJ; Assikis, V; Belkoff, L; Carducci, MA; Damber, JE; Forsberg, G; Gingrich, JR; Häggman, M; Nordle, Ö; Pili, R; Polikoff, J; Stadler, WM1
Bjarnason, GA; Cai, C; Davis, ID; De Giorgi, U; Escudier, B; Esteban, E; Grünwald, V; Kollmannsberger, C; Lee, JL; Marker, M; Melichar, B; Motzer, RJ; Porta, C; Rha, SY; Shi, MM; Squires, M; Sternberg, CN; Szczylik, C; Urbanowitz, G; Vogelzang, NJ; Zolnierek, J1
Angevin, E; Beall, S; Castellano, D; Escudier, B; Grünwald, V; Gschwend, JE; Harzstark, A; Lin, CC; Ou, YC; Pirotta, N; Ravaud, A; Shi, M; Squires, M1
Bajorin, D; Cerbone, L; Dittrich, C; Durán, I; Jagdev, S; Lochheed, M; Millard, FE; Milowsky, MI; Quinn, DI; Rosenberg, JE; Sen, P; Shi, M; Squires, M; Stadler, WM; Sternberg, CN; Sweeney, CJ1
Bang, YJ; Cho, BC; Keam, B; Kim, MK; Kim, SB; Lee, KW; Lee, SH; Shin, SH; Yoon, DH; Yun, HJ1
Finkler, N; Fong, PC; Garcia, AA; Konecny, GE; Kristeleit, R; Lee, PS; Lorusso, D; Mishra, K; Rocconi, RP; Squires, M; Upalawanna, A; Wang, Y1
Das, M; Frymoyer, A; Neal, JW; Padda, SK; Riess, JW; Wakelee, HA; Zhou, L1
Damber, JE; Hagberg Thulin, M; Magnusson, LU; Olsson, A; Plas, P; Welén, K1
Feng, Q; Gao, T; Lei, Q; Shi, Y; Song, X; Wang, N; Wei, Y; Xia, Y; Xiong, M; Yang, F; Ye, T; You, X; Yu, L; Zhang, L; Zhu, Y1
Agarwal, N; Armstrong, A; Baton, F; Bögemann, M; Brize, A; Carducci, M; Chowdhury, S; Delva, R; Gallardo, E; Harza, M; Huddart, R; Hutson, T; James, N; Khvorostenko, D; Lyulko, O; Milecki, P; Nederman, T; Ng, S; Pili, R; Pouget, JC; Schwartsmann, G; Sternberg, C; Thanos, A; Tuvesson, H; Vogelzang, N; Werbrouck, P1
André, F; Barrios, CH; Blackwell, K; Bonnefoi, H; Campone, M; Cortes, J; Denduluri, N; Deudon, S; Kahan, Z; Musolino, A; Neven, P; Shi, MM; Soliman, H; Squires, M; Zhang, Y1
Christos, PJ; Hershman, DL; Hoschander, S; Li, T; O'Brien, K; Sparano, JA; Vahdat, LT; Wright, JJ1
Allal, BC; Chaoui, K; Dalenc, F; Doisneau-Sixou, SF; Favre, G; Filleron, T; Lauwers-Cances, V; Malissein, E; Marsili, S; Meunier, E; Monsarrat, B; Renée, N; Roché, H; Schiltz, O1
Chung, JG; Hsu, SC; Huang, CC; Ip, SW; Kuo, CL; Kuo, SC; Lai, KC; Lai, TY; Lin, SY; Wood, WG; Yang, JS1
Bernhard, JC; De Clermont, H; Gross-Goupil, M; Quivy, A; Ravaud, A; Roca, S1
Armstrong, AJ; Assikis, VJ; Björk, A; Carducci, MA; Forsberg, G; Gingrich, JR; Häggman, M; Nordle, O; Pili, R; Stadler, WM1
Akerley, WL; Flaherty, LE; Kirkwood, JM; Lao, CD; Margolin, KA; Moon, J; Othus, M; Sondak, VK; Sosman, JA1
Axelsson, B; Damber, JE; Jennbacken, K; Leanderson, T; Olsson, A; Törngren, M; Welén, K1
Chen, ZY; Guo, RP; Guo, ZX; Li, SH; Li, XJ; Peng, LX; Qian, CN; Shi, M; Wei, W; Zhong, C1
Li, T; Sparano, JA1
Abbruzzese, JL; Alpaugh, RK; Beard, M; Cohen, SJ; Ho, L; Hudes, GR; Lewis, NL; McLaughlin, S; Meropol, NJ; Perez-Ruixo, JJ; Ranganathan, S; Rogatko, A; Thistle, AM; Verhaeghe, T; Wang, H; Weiner, LM; Wright, JJ1
Dowsett, M; Ellis, P; Hickish, T; Houston, S; Howes, A; Johnston, SR; Kelland, L; Michiels, B; Palmer, P; Perez-Ruixo, JJ; Salter, J1
Balis, FM; Chow, C; Clark, G; Eng-Wong, J; Gantz, SB; Jayaprakash, N; Lebowitz, PF; Venzon, D; Widemann, BC; Zujewski, J1
Chang, YL; Guh, JH; Huang, DY; Kuo, SC; Lee, KH; Pan, SL; Peng, CY; Teng, CM; Tsai, AC; Wang, SW1
Andela, VB; O'Keefe, RJ; Puzas, EJ; Rosenblatt, JD; Rosier, RN; Schwarz, EM1

Reviews

1 review(s) available for carbostyril and Metastase

ArticleYear
Inhibiting Ras signaling in the therapy of breast cancer.
    Clinical breast cancer, 2003, Volume: 3, Issue:6

    Topics: Alkyl and Aryl Transferases; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Farnesyltranstransferase; Female; GTP-Binding Proteins; Humans; Mutation; Neoplasm Metastasis; Quinolones; ras Proteins; Signal Transduction

2003

Trials

21 trial(s) available for carbostyril and Metastase

ArticleYear
Tipifarnib in recurrent, metastatic HRAS-mutant salivary gland cancer.
    Cancer, 2020, 09-01, Volume: 126, Issue:17

    Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Progression-Free Survival; Proto-Oncogene Proteins p21(ras); Quinolones; Salivary Gland Neoplasms; Treatment Outcome

2020
A Phase II Trial of Tipifarnib for Patients with Previously Treated, Metastatic Urothelial Carcinoma Harboring
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 10-01, Volume: 26, Issue:19

    Topics: Aged; AMP-Activated Protein Kinase Kinases; Carcinoma; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Middle Aged; Mutation; Neoplasm Metastasis; Progression-Free Survival; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins p21(ras); Quinolones; Urothelium

2020
A Phase II Study of Dovitinib in Patients with Recurrent or Metastatic Adenoid Cystic Carcinoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2017, Aug-01, Volume: 23, Issue:15

    Topics: Adult; Aged; Benzimidazoles; Carcinoma, Adenoid Cystic; Cell Proliferation; Disease-Free Survival; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Oncogene Proteins v-myb; Quinolones; Receptor, Fibroblast Growth Factor, Type 1

2017
Phase II Study of Dovitinib in Patients with Castration-Resistant Prostate Cancer (KCSG-GU11-05).
    Cancer research and treatment, 2018, Volume: 50, Issue:4

    Topics: Aged; Aged, 80 and over; Benzimidazoles; Biomarkers, Tumor; Docetaxel; Drug Administration Schedule; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms, Castration-Resistant; Protein Kinase Inhibitors; Quinolones; Receptor, Fibroblast Growth Factor, Type 2; Survival Analysis; Treatment Outcome; Vascular Endothelial Growth Factor Receptor-2

2018
A phase II study of tipifarnib and gemcitabine in metastatic breast cancer.
    Investigational new drugs, 2018, Volume: 36, Issue:2

    Topics: Adult; Aged; Breast Neoplasms; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; Humans; Kaplan-Meier Estimate; Middle Aged; Neoplasm Metastasis; Quinolones; Treatment Outcome

2018
Long-term survival and biomarker correlates of tasquinimod efficacy in a multicenter randomized study of men with minimally symptomatic metastatic castration-resistant prostate cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Dec-15, Volume: 19, Issue:24

    Topics: Biomarkers, Tumor; Bone Neoplasms; C-Reactive Protein; Disease-Free Survival; Humans; L-Lactate Dehydrogenase; Male; Neoplasm Metastasis; Prostatic Neoplasms, Castration-Resistant; Quinolines; Quinolones; Survival Analysis; Vascular Endothelial Growth Factor A

2013
Dovitinib versus sorafenib for third-line targeted treatment of patients with metastatic renal cell carcinoma: an open-label, randomised phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzimidazoles; Carcinoma, Renal Cell; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Quinolones; Sorafenib; Vascular Endothelial Growth Factor A

2014
Phase II results of Dovitinib (TKI258) in patients with metastatic renal cell cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Jun-01, Volume: 20, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzimidazoles; Carcinoma, Renal Cell; Disease-Free Survival; Female; Fibroblast Growth Factor-23; Humans; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Quinolones; Receptors, Vascular Endothelial Growth Factor; Salvage Therapy

2014
Phase 2 trial of dovitinib in patients with progressive FGFR3-mutated or FGFR3 wild-type advanced urothelial carcinoma.
    European journal of cancer (Oxford, England : 1990), 2014, Volume: 50, Issue:18

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Benzimidazoles; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Mutation; Neoplasm Metastasis; Quinolones; Receptor, Fibroblast Growth Factor, Type 3; Treatment Outcome; Urologic Neoplasms

2014
Phase 2 study of dovitinib in patients with metastatic or unresectable adenoid cystic carcinoma.
    Cancer, 2015, Aug-01, Volume: 121, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Benzimidazoles; Carcinoma, Adenoid Cystic; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Metastasis; Quinolones; Republic of Korea; Salivary Gland Neoplasms; Treatment Outcome; Young Adult

2015
Second-line dovitinib (TKI258) in patients with FGFR2-mutated or FGFR2-non-mutated advanced or metastatic endometrial cancer: a non-randomised, open-label, two-group, two-stage, phase 2 study.
    The Lancet. Oncology, 2015, Volume: 16, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Disease-Free Survival; Endometrial Neoplasms; Female; Humans; Kaplan-Meier Estimate; Middle Aged; Mutation; Neoplasm Metastasis; Neoplasm Staging; Quinolones; Receptor, Fibroblast Growth Factor, Type 2; Treatment Outcome

2015
Dovitinib and erlotinib in patients with metastatic non-small cell lung cancer: A drug-drug interaction.
    Lung cancer (Amsterdam, Netherlands), 2015, Volume: 89, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinoma, Non-Small-Cell Lung; Drug Interactions; Erlotinib Hydrochloride; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Neoplasm Metastasis; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Quinolones; Receptors, Vascular Endothelial Growth Factor; Retreatment; Treatment Outcome

2015
Randomized, Double-Blind, Placebo-Controlled Phase III Study of Tasquinimod in Men With Metastatic Castration-Resistant Prostate Cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 08-01, Volume: 34, Issue:22

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Double-Blind Method; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms, Castration-Resistant; Quinolones

2016
Phase II, randomized, placebo-controlled study of dovitinib in combination with fulvestrant in postmenopausal patients with HR
    Breast cancer research : BCR, 2017, 02-10, Volume: 19, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Disease Progression; Estradiol; Female; Fulvestrant; Humans; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Postmenopause; Quinolones; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Retreatment; Survival Analysis; Treatment Outcome

2017
Phase II trial of the farnesyltransferase inhibitor tipifarnib plus fulvestrant in hormone receptor-positive metastatic breast cancer: New York Cancer Consortium Trial P6205.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Estradiol; Farnesyltranstransferase; Female; Fulvestrant; Humans; Middle Aged; Neoplasm Metastasis; Quinolones; Receptors, Estrogen; Receptors, Progesterone; Treatment Outcome

2009
Tipifarnib plus tamoxifen in tamoxifen-resistant metastatic breast cancer: a negative phase II and screening of potential therapeutic markers by proteomic analysis.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Feb-15, Volume: 16, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Resistance, Neoplasm; Farnesyltranstransferase; Female; Humans; Middle Aged; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Postmenopause; Protein Array Analysis; Quinolones; Tamoxifen

2010
Phase II randomized, double-blind, placebo-controlled study of tasquinimod in men with minimally symptomatic metastatic castrate-resistant prostate cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Oct-20, Volume: 29, Issue:30

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Calgranulin B; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Male; Middle Aged; Molecular Targeted Therapy; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Orchiectomy; Placebos; Prostatic Neoplasms; Quinolines; Quinolones

2011
Randomized phase II trial of sorafenib with temsirolimus or tipifarnib in untreated metastatic melanoma (S0438).
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Feb-15, Volume: 18, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Pyridines; Quinolones; Sirolimus; Sorafenib; Survival Analysis; Treatment Outcome

2012
Phase II and pharmacodynamic study of the farnesyltransferase inhibitor R115777 as initial therapy in patients with metastatic pancreatic adenocarcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Apr-01, Volume: 21, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Alkyl and Aryl Transferases; Antineoplastic Agents; Carrier Proteins; Disease Progression; Farnesyltranstransferase; Female; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; Humans; Male; Middle Aged; Neoplasm Metastasis; Pancreatic Neoplasms; Quinolones; Treatment Outcome

2003
Phase II study of the efficacy and tolerability of two dosing regimens of the farnesyl transferase inhibitor, R115777, in advanced breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jul-01, Volume: 21, Issue:13

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Middle Aged; Neoplasm Metastasis; Neutropenia; Quinolones; Thrombocytopenia; Treatment Outcome

2003
A phase I trial and pharmacokinetic study of tipifarnib, a farnesyltransferase inhibitor, and tamoxifen in metastatic breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Feb-01, Volume: 11, Issue:3

    Topics: Adult; Aged; Alkyl and Aryl Transferases; Anemia; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Dose-Response Relationship, Drug; Exanthema; Farnesyltranstransferase; Fatigue; Female; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Neoplasm Metastasis; Quinolones; Tamoxifen; Treatment Outcome

2005

Other Studies

11 other study(ies) available for carbostyril and Metastase

ArticleYear
T-LAK cell-originated protein kinase (TOPK) is a Novel Prognostic and Therapeutic Target in Chordoma.
    Cell proliferation, 2020, Volume: 53, Issue:10

    Topics: Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Chordoma; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Mitogen-Activated Protein Kinase Kinases; Neoplasm Metastasis; Prognosis; Protein Kinase Inhibitors; Quinolones; RNA Interference; RNA, Small Interfering; Thiophenes

2020
Prevention of epithelial to mesenchymal transition in colorectal carcinoma by regulation of the E-cadherin-β-catenin-vinculin axis.
    Cancer letters, 2019, 06-28, Volume: 452

    Topics: Antigens, CD; Antineoplastic Agents; Benzimidazoles; beta Catenin; Cadherins; Cell Adhesion; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Epithelial-Mesenchymal Transition; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Proto-Oncogene Proteins c-akt; Quinolones; Transforming Growth Factor beta; Vinculin

2019
Nodal pathway activation due to Akt1 suppression is a molecular switch for prostate cancer cell epithelial-to-mesenchymal transition and metastasis.
    Biochemical pharmacology, 2019, Volume: 168

    Topics: Animals; Benzodioxoles; Cell Movement; Cell Survival; Epithelial-Mesenchymal Transition; Forkhead Box Protein O3; Gene Silencing; Humans; Imidazoles; Lung Neoplasms; Male; Mice; Mice, Nude; Neoplasm Metastasis; Nodal Protein; PC-3 Cells; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Pyridines; Quinolones; Tumor Burden; Xenograft Model Antitumor Assays

2019
Tasquinimod inhibits prostate cancer growth in bone through alterations in the bone microenvironment.
    The Prostate, 2016, Volume: 76, Issue:4

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cytokines; Heterografts; Humans; Immune Tolerance; Inflammation; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Osteoblasts; Osteogenesis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Quinolines; Quinolones; Tibia; Tumor Microenvironment; Xenograft Model Antitumor Assays

2016
Selective inhibition of EZH2 by ZLD1039 blocks H3K27 methylation and leads to potent anti-tumor activity in breast cancer.
    Scientific reports, 2016, Feb-12, Volume: 6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Female; Histones; Humans; Intracellular Space; Methylation; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Polycomb Repressive Complex 2; Pyridones; Quinolones; Small Molecule Libraries; Transcriptional Activation; Xenograft Model Antitumor Assays

2016
2-(3-Methoxyphenyl)-6, 7-methylenedioxoquinolin-4-one, a novel synthetic compound, inhibited migration and invasion in TSGH8301 human bladder cancer cells.
    Human & experimental toxicology, 2011, Volume: 30, Issue:8

    Topics: Antineoplastic Agents; Benzodioxoles; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Screening Assays, Antitumor; Humans; Matrix Metalloproteinase Inhibitors; Molecular Structure; Neoplasm Invasiveness; Neoplasm Metastasis; Quinolones

2011
Efficacy of re-challenging metastatic renal cell carcinoma with mTOR inhibitors.
    Acta oncologica (Stockholm, Sweden), 2011, Volume: 50, Issue:7

    Topics: Antineoplastic Agents; Benzimidazoles; Carcinoma, Renal Cell; Everolimus; Humans; Indoles; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Quinolones; Sirolimus; Sunitinib; TOR Serine-Threonine Kinases

2011
Inhibition of metastasis in a castration resistant prostate cancer model by the quinoline-3-carboxamide tasquinimod (ABR-215050).
    The Prostate, 2012, Jun-01, Volume: 72, Issue:8

    Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Line, Tumor; Down-Regulation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice; Mice, Nude; Neoplasm Metastasis; Orchiectomy; Prostatic Neoplasms; Quinolines; Quinolones; Treatment Outcome; Up-Regulation; Xenograft Model Antitumor Assays

2012
Dovitinib preferentially targets endothelial cells rather than cancer cells for the inhibition of hepatocellular carcinoma growth and metastasis.
    Journal of translational medicine, 2012, Dec-10, Volume: 10

    Topics: Animals; Apoptosis; Benzimidazoles; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Endothelial Cells; Humans; Liver Neoplasms; Male; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Neovascularization, Pathologic; Protein Kinase Inhibitors; Quinolones; Receptor Protein-Tyrosine Kinases; Signal Transduction; Xenograft Model Antitumor Assays

2012
CHM-1 inhibits hepatocyte growth factor-induced invasion of SK-Hep-1 human hepatocellular carcinoma cells by suppressing matrix metalloproteinase-9 expression.
    Cancer letters, 2007, Nov-08, Volume: 257, Issue:1

    Topics: Antineoplastic Agents; Cell Line, Tumor; Dioxoles; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Humans; I-kappa B Kinase; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Models, Biological; Models, Chemical; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; Phosphorylation; Quinolones

2007
Synergism of aminobisphosphonates and farnesyl transferase inhibitors on tumor metastasis.
    Clinical orthopaedics and related research, 2002, Issue:397

    Topics: Alendronate; Alkyl and Aryl Transferases; Animals; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Farnesyltranstransferase; Female; Flow Cytometry; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Quinolones; Tumor Cells, Cultured

2002