carbostyril has been researched along with Malignant Melanoma in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 13 (72.22) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Božić, B; Jelača, S; Kaluđerović, GN; Kasalović, MP; Lađarević, J; Maksimović-Ivanić, D; Mijatović, S; Pantelić, NĐ; Radovanović, L | 1 |
| Becker, JP; Berger, W; Evidente, A; Hutton, J; Kinzy, TG; Kiss, R; Kornienko, A; Lallemand, B; Lefranc, F; Mathieu, V; Pelletier, J; Pirker, C; Prévost, M; Robert, F; Van Antwerpen, P; Van Goietsenoven, G; Vandenbussche, G | 1 |
| Alanazi, MM; Bang, EK; Cho, KH; El-Damasy, AK; Keum, G; Kim, HJ; Park, JW; Seo, S | 1 |
| Janošková, M; Jantová, S; Milata, V; Pánik, M; Paulovičová, E; Paulovičová, L | 1 |
| Guchelaar, HJ; Herings, RM; Koomen, ER; Nijsten, TE; Siiskonen, SJ; Stricker, BH; Visser, LE | 1 |
| Barile, E; Chen, V; De, SK; Feng, Y; Pellecchia, M; Ronai, Z; Yang, L | 1 |
| Bentke, A; Krzykowska-Petitjean, K; Laidler, P; Małecki, J; Ostrowska, B | 1 |
| Chen, K; Li, B; Shen, J; Wang, G; Wang, H; Xu, Z; Yang, M; Zeng, B; Zhu, W | 1 |
| Bosenberg, MW; Held, MA; Iyidogan, P; Klein, M; Koo, AB; Langdon, CG; Liu, Z; Mamillapalli, R; Meeth, K; Platt, JT; Stern, DF | 1 |
| Barile, E; Bosenberg, M; Brown, KM; Cheli, Y; Davies, MA; De, SK; Feng, Y; Grotegut, S; Hassig, CA; Hulea, L; James, B; Kim, H; Lau, E; Li, JL; Pellecchia, M; Pinkerton, AB; Ronai, ZA; Topisirovic, I; Yin, H; Zhang, T | 1 |
| De, SK; Dewing, A; Gaitonde, S; Krajewski, S; Pellecchia, M; Riel-Mehan, M; Robertson, G; Ronai, Z; Tcherpakov, M; Yuan, H | 1 |
| Aza-Blanc, P; Barile, E; Chiang, GG; Cortez, A; De, SK; Feng, Y; Heryln, M; Krajewski, S; Pellecchia, M; Ronai, ZA; Stebbins, JL; Villanueva, J | 1 |
| Chesney, J; Gardner, H; Kim, KB; Kirkwood, JM; Robinson, D; Shi, MM | 1 |
| Akerley, WL; Flaherty, LE; Kirkwood, JM; Lao, CD; Margolin, KA; Moon, J; Othus, M; Sondak, VK; Sosman, JA | 1 |
| Aza-Blanc, P; Barile, E; Bosenberg, M; Chin, L; De, SK; Feng, Y; Jackson, M; Krajewski, S; Lau, E; Pellecchia, M; Pinkerton, AB; Ronai, ZA; Ruller, C; Scortegagna, M; Williams, R | 1 |
| Blaskovich, MA; Bucher, C; Gajewski, TF; Haluska, F; Johnson, J; Linette, G; Niedzwiecki, D; Salama, AK; Sebti, SM | 1 |
| Chang, JJ; Hamel, E; Juang, JP; Kuo, SC; Lednicer, D; Lee, HZ; Lin, CM; Lin, YT; Paull, KD; Wu, TS | 1 |
| Amos, WB; Blunt, N; Craven, MR; Errington, RJ; Hoy, T; Patterson, LH; Smith, PJ; Teesdale-Spittle, P; Watson, JV; Wiltshire, M | 1 |
3 trial(s) available for carbostyril and Malignant Melanoma
| Article | Year |
|---|---|
Phase I/II and pharmacodynamic study of dovitinib (TKI258), an inhibitor of fibroblast growth factor receptors and VEGF receptors, in patients with advanced melanoma.
Topics: Adult; Aged; Antineoplastic Agents; Benzimidazoles; Biomarkers, Tumor; Drug Administration Schedule; Female; Fibroblast Growth Factor-23; Humans; Male; Melanoma; Middle Aged; Protein Kinase Inhibitors; Quinolones; Receptors, Fibroblast Growth Factor; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor | 2011 |
Randomized phase II trial of sorafenib with temsirolimus or tipifarnib in untreated metastatic melanoma (S0438).
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Pyridines; Quinolones; Sirolimus; Sorafenib; Survival Analysis; Treatment Outcome | 2012 |
Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104).
Topics: Adult; Aged; Aged, 80 and over; Biopsy; Cell Line, Tumor; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Farnesyltranstransferase; Female; HSP40 Heat-Shock Proteins; Humans; Interferon-gamma; Male; Melanoma; Middle Aged; Neoplasm Staging; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinolones; Signal Transduction; Skin Neoplasms; T-Lymphocytes; Treatment Outcome | 2012 |
15 other study(ies) available for carbostyril and Malignant Melanoma
| Article | Year |
|---|---|
Novel diphenyltin(IV) complexes with carboxylato N-functionalized 2-quinolone ligands: Synthesis, characterization and in vitro anticancer studies.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Coordination Complexes; Female; Humans; Ligands; Melanoma; Mice; Spectroscopy, Fourier Transform Infrared | 2024 |
Targeting of eEF1A with Amaryllidaceae isocarbostyrils as a strategy to combat melanomas.
Topics: Amaryllidaceae Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Binding Sites; Cell Line, Tumor; Cytoskeleton; Drug Delivery Systems; Gene Expression Regulation; Humans; Hydroxyquinolines; Liliaceae; Melanoma; Mice; Models, Molecular; Peptide Elongation Factor 1; Phenanthridines; Quinolones; Saccharomyces cerevisiae | 2010 |
Discovery of New Quinolone-Based Diarylamides as Potent B-RAF
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Melanoma; Molecular Docking Simulation; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Quinolones; Structure-Activity Relationship | 2023 |
Immunobiological efficacy and immunotoxicity of novel synthetically prepared fluoroquinolone ethyl 6-fluoro-8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylate.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 9; Cell Growth Processes; Cell Survival; Cytokines; Epidermis; Female; Fibroblasts; Fluoroquinolones; HeLa Cells; HL-60 Cells; Humans; Immunologic Factors; Melanoma; Melanoma, Experimental; Mice; NIH 3T3 Cells; Quinolines; Quinolones; RAW 264.7 Cells; Uterine Cervical Neoplasms | 2018 |
Exposure to phototoxic NSAIDs and quinolones is associated with an increased risk of melanoma.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cohort Studies; Databases, Factual; Dermatitis, Phototoxic; Drug Prescriptions; Female; Follow-Up Studies; Humans; Male; Melanoma; Middle Aged; Netherlands; Propionates; Prospective Studies; Quinolones; Registries; Risk; Skin; Skin Neoplasms | 2013 |
Synthesis and SAR studies of dual AKT/NF-κB inhibitors against melanoma.
Topics: Animals; Benzimidazoles; Cell Line, Tumor; Cell Survival; Enzyme Activation; Female; Humans; Melanoma; Mice; Mice, Nude; NF-kappa B; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinolones; Structure-Activity Relationship; Transplantation, Heterologous | 2013 |
Tanespimycin and tipifarnib exhibit synergism in inducing apoptosis in melanoma cell lines from later stages of tumor progression.
Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Melanoma; Protein Serine-Threonine Kinases; Quinolones | 2013 |
Overman rearrangement and Pomeranz-Fritsch reaction for the synthesis of benzoazepinoisoquinolones to discover novel antitumor agents.
Topics: Antineoplastic Agents; Benzazepines; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; HCT116 Cells; Hep G2 Cells; Humans; Indoles; K562 Cells; Melanoma; Molecular Structure; Niacinamide; Phenylurea Compounds; Quinolones; Sorafenib; Structure-Activity Relationship; Sulfonamides; Vemurafenib | 2013 |
The broad-spectrum receptor tyrosine kinase inhibitor dovitinib suppresses growth of BRAF-mutant melanoma cells in combination with other signaling pathway inhibitors.
Topics: Animals; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Humans; Indoles; Male; Melanoma; Melanoma, Cutaneous Malignant; Mice, Nude; Mutation; Neoplasm Proteins; Protein Kinase Inhibitors; Quinolones; Signal Transduction; Skin Neoplasms; Small Molecule Libraries; Sulfonamides; Vemurafenib | 2015 |
SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Eukaryotic Initiation Factor-4F; Gene Knockout Techniques; Humans; Lactams; Melanoma; Mice; Quinolones | 2015 |
BI-69A11-mediated inhibition of AKT leads to effective regression of xenograft melanoma.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Benzimidazoles; Cell Death; Cell Line, Tumor; Enzyme Activation; HSP90 Heat-Shock Proteins; Humans; Male; Melanoma; Mice; Mice, Nude; Models, Molecular; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Quinolones; Remission Induction; Xenograft Model Antitumor Assays | 2009 |
Effective inhibition of melanoma by BI-69A11 is mediated by dual targeting of the AKT and NF-κB pathways.
Topics: Administration, Oral; Animals; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Humans; Melanoma; Mice; Mice, Nude; Molecular Targeted Therapy; NF-kappa B; Phosphotransferases (Alcohol Group Acceptor); Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Quinolones; Signal Transduction; Skin Neoplasms; Xenograft Model Antitumor Assays | 2011 |
Inhibition of melanoma development in the Nras((Q61K)) ::Ink4a(-/-) mouse model by the small molecule BI-69A11.
Topics: Amino Acid Substitution; Animals; Benzimidazoles; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Injections, Intraperitoneal; Ki-67 Antigen; Leukocyte Common Antigens; Melanoma; Mice; Precancerous Conditions; Proto-Oncogene Proteins B-raf; Quinolones; ras Proteins; Skin Neoplasms; Small Molecule Libraries; Xenograft Model Antitumor Assays | 2013 |
Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin.
Topics: Animals; Antineoplastic Agents; Humans; Intestinal Neoplasms; Leukemia L1210; Leukemia P388; Lung Neoplasms; Melanoma; Mice; Molecular Structure; Nasopharyngeal Neoplasms; Quinolines; Quinolones; Software; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 1993 |
Characteristics of a novel deep red/infrared fluorescent cell-permeant DNA probe, DRAQ5, in intact human cells analyzed by flow cytometry, confocal and multiphoton microscopy.
Topics: Anthraquinones; CDC2 Protein Kinase; Cell Cycle; Cyclin B; Cyclin B1; Diagnostic Imaging; DNA Probes; DNA, Neoplasm; Flow Cytometry; Fluorescent Antibody Technique; Fluorescent Dyes; Gene Expression; Green Fluorescent Proteins; Humans; Infrared Rays; Luminescent Proteins; Melanoma; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Structure; Nitrogen Oxides; Quinolones; Spectrophotometry; Tosyl Compounds; Tumor Cells, Cultured | 2000 |