Compounds > carbostyril
Page last updated: 2024-08-17

carbostyril and Malaria

carbostyril has been researched along with Malaria in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.52)18.7374
1990's0 (0.00)18.2507
2000's2 (9.52)29.6817
2010's15 (71.43)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
TAGGART, JV; WELCH, WJ1
Chang, L; Ding, C; Feng, LS; Gao, C; Li, C; Shi, F; Wu, X; Xu, Z; Yan, XF; Zhao, F1
Asakawa, AH; Brockmeyer, F; Casandra, D; Huang, L; Kyle, DE; LaCrue, AN; Maher, SP; Maignan, JR; Manetsch, R; Mashkouri, S; Monastyrskyi, A; Padin-Irizarry, V; Parvatkar, PT; Sakhno, YI; Zhao, Y1
Campbell, RF; Caridha, D; Forquer, IP; Frueh, L; Kelly, JX; Koop, DR; Kreishman-Deitrick, M; Li, Q; Li, Y; Mather, MW; Nilsen, A; Pershing, AM; Pou, S; Riscoe, MK; Sciotti, RJ; Smilkstein, MJ; Vaidya, AB; Vesely, B; Winter, RW; Xie, LH1
Angulo-Barturen, I; Avery, VM; Bathurst, I; Burrows, JN; Charman, SA; Cross, RM; Delves, MJ; Duffy, S; Ferrer, S; Forquer, IP; Gamo, FJ; Guy, RK; Herreros, E; Jiménez-Díaz, MB; Kelly, JX; Kocken, CHM; Kyle, DE; LaCrue, AN; Li, Y; Manetsch, R; Marfurt, J; Mather, MW; Morrisey, JM; Mutka, T; Nilsen, A; Noviyanti, R; Price, RN; Riscoe, MK; Ryan, E; Saenz, FE; Sanz, LM; Sebayang, BF; Shackleford, DM; Siegl, P; Sinden, RE; Steuten, J; Vaidya, AB; White, KL; Winter, RW; Wirjanata, G; Zeeman, AM1
Ojha, PK; Roy, K1
Cross, RM; Kyle, DE; Lacrue, AN; Maignan, JR; Manetsch, R; Sáenz, FE; Udenze, KO1
Kyle, DE; Manetsch, R; Monastyrskyi, A1
Bathurst, I; Burrows, JN; Charman, SA; Cross, RM; Flanigan, DL; Fronczek, FR; Guida, WC; Kyle, DE; LaCrue, AN; Maignan, JR; Manetsch, R; Monastyrskyi, A; Mutka, TS; Sáenz, FE; Shackleford, DM; White, KL; Wojtas, L1
Barigye, SJ; Duarte, MH; Freitas, MP1
Burrows, JN; Charman, SA; Chen, G; Donini, C; Forquer, IP; Kelly, JX; Kim, K; Li, Y; Mather, MW; Miley, GP; Nilsen, A; Pershing, AM; Pou, S; Riscoe, MK; Saunders, J; Shackleford, D; Stickles, AM; Ting, LM; Vaidya, AB; White, K; Winter, R; Zakharov, LN1
Huang, W; Huang, X; Kim, M; McKew, JC; Patel, PR; Sanderson, PE; Simeonov, A; Sun, W; Tanaka, TQ; Williamson, KC; Zheng, W1
Muregi, FW1
Hinrichs, D; Kelly, JX; Koop, DR; Riscoe, MK; Smilkstein, MJ; Winter, R1
Akala, HM; Bedno, SA; Coldren, RL; Eyase, FL; Moss, WJ; Prigge, ST; Spalding, MD; Waters, NC1
Amewu, R; Berger, O; Berry, NG; Biagini, GA; Charoensutthivarakul, S; Fisher, NE; Gibbons, P; Hill, A; Hong, WD; Leung, SC; Mbekeani, A; Nixon, GL; O'Neill, PM; Pacorel, B; Pidathala, C; Sharma, R; Shone, AE; Srivastava, A; Stocks, PA; Taylor, L; Ward, SA; Warman, AJ2
Cross, RM; Kyle, DE; Lacrue, AN; Manetsch, R; Monastyrskyi, A; Mutka, TS; Sáenz, FE; Stein, S; Udenze, KO1
Bauer, KD; Bendale, P; Buckner, FS; Chakrabarti, D; Floyd, D; Gelb, MH; Hamilton, A; Hornéy, CP; Lombardo, LJ; Nallan, L; Pendyala, PR; Rivas, K; Sebti, S; Van Voorhis, WC; Weber, PC; Williams, DK; Windsor, WT; Yokoyama, K1
Charris, JE; Domínguez, JN; Gamboa de Domínguez, N; Lobo, G; Moreno, MM; Olson, J; Riggione, F; Rosenthal, PJ; Sanchez, E1
Wyler, DJ1

Reviews

1 review(s) available for carbostyril and Malaria

ArticleYear
Hybrid molecules with potential in vitro antiplasmodial and in vivo antimalarial activity against drug-resistant Plasmodium falciparum.
    Medicinal research reviews, 2020, Volume: 40, Issue:3

    Topics: Animals; Antimalarials; CHO Cells; Cricetulus; Drug Design; Drug Resistance; Humans; In Vitro Techniques; Inhibitory Concentration 50; Malaria; Molecular Structure; Pharmaceutical Preparations; Plasmodium falciparum; Quinolines; Quinolones

2020

Other Studies

20 other study(ies) available for carbostyril and Malaria

ArticleYear
Cinchona alkaloids; suppressive antimalarial activity of cinchonine carbostyril.
    Federation proceedings, 1946, Volume: 5, Issue:1 Pt 2

    Topics: Antimalarials; Cinchona; Cinchona Alkaloids; Humans; Hydroxyquinolines; Malaria; Quinolones

1946
Aminoalkoxycarbonyloxymethyl Ether Prodrugs with a pH-Triggered Release Mechanism: A Case Study Improving the Solubility, Bioavailability, and Efficacy of Antimalarial 4(1
    Journal of medicinal chemistry, 2021, 05-27, Volume: 64, Issue:10

    Topics: Administration, Oral; Animals; Antimalarials; Cyclization; Disease Models, Animal; Ethers; Female; Half-Life; Hydrogen-Ion Concentration; Malaria; Mice; Mice, Inbred BALB C; Plasmodium falciparum; Prodrugs; Quinolones; Solubility; Structure-Activity Relationship

2021
Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria.
    ACS infectious diseases, 2017, 10-13, Volume: 3, Issue:10

    Topics: Animals; Antimalarials; Electron Transport Complex III; Malaria; Mice; Mitochondria; Molecular Structure; Plasmodium falciparum; Prodrugs; Quinolones

2017
Quinolone-3-diarylethers: a new class of antimalarial drug.
    Science translational medicine, 2013, Mar-20, Volume: 5, Issue:177

    Topics: Animals; Antimalarials; Atovaquone; Drug Resistance; Drug Synergism; Life Cycle Stages; Malaria; Malaria, Falciparum; Mice; Plasmodium falciparum; Plasmodium vivax; Proguanil; Pyridones; Quinolones

2013
Exploration of important sites of antimalarial Endochins for optimum structural modification using group-based QSAR (G-QSAR) modeling.
    Current computer-aided drug design, 2013, Volume: 9, Issue:3

    Topics: Algorithms; Antimalarials; Humans; Malaria; Models, Molecular; Plasmodium; Quantitative Structure-Activity Relationship; Quinolones

2013
4-(1H)-Quinolones and 1,2,3,4-Tetrahydroacridin-9(10H)-ones prevent the transmission of Plasmodium falciparum to Anopheles freeborni.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12

    Topics: Acridines; Animals; Anopheles; Antimalarials; Female; Humans; Insect Vectors; Life Cycle Stages; Malaria; Malaria, Falciparum; Male; Mice; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Quinolones; Salivary Glands; Structure-Activity Relationship

2013
4(1H)-pyridone and 4(1H)-quinolone derivatives as antimalarials with erythrocytic, exoerythrocytic, and transmission blocking activities.
    Current topics in medicinal chemistry, 2014, Volume: 14, Issue:14

    Topics: Animals; Antimalarials; Drug Evaluation, Preclinical; Erythrocytes; Malaria; Pyridones; Quinolones; Structure-Activity Relationship

2014
Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium.
    Journal of medicinal chemistry, 2014, Nov-13, Volume: 57, Issue:21

    Topics: Animals; Antimalarials; Humans; Inhibitory Concentration 50; Malaria; Mice; Microsomes, Liver; Parasitemia; Plasmodium; Plasmodium berghei; Quinolones; Structure-Activity Relationship

2014
Exploring MIA-QSARs' for antimalarial quinolon-4(1H)-imines.
    Combinatorial chemistry & high throughput screening, 2015, Volume: 18, Issue:2

    Topics: Antimalarials; Discriminant Analysis; Humans; Imines; Least-Squares Analysis; Linear Models; Malaria; Multivariate Analysis; Plasmodium; Quantitative Structure-Activity Relationship; Quinolones

2015
ELQ-300 prodrugs for enhanced delivery and single-dose cure of malaria.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:9

    Topics: Animals; Antimalarials; Crystallography, X-Ray; Electron Transport Complex III; Female; Malaria; Mice; Plasmodium falciparum; Prodrugs; Quinolones

2015
In vitro evaluation of imidazo[4,5-c]quinolin-2-ones as gametocytocidal antimalarial agents.
    Bioorganic & medicinal chemistry letters, 2016, 06-15, Volume: 26, Issue:12

    Topics: Antimalarials; Cell Survival; Dose-Response Relationship, Drug; Hep G2 Cells; High-Throughput Screening Assays; Humans; Imidazoles; Malaria; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolones; Structure-Activity Relationship

2016
Antimalarial drugs and their useful therapeutic lives: rational drug design lessons from pleiotropic action of quinolines and artemisinins.
    Current drug discovery technologies, 2010, Volume: 7, Issue:4

    Topics: Animals; Antimalarials; Artemisinins; Drug Delivery Systems; Drug Design; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Quinolones; Time Factors

2010
Optimization of endochin-like quinolones for antimalarial activity.
    Experimental parasitology, 2011, Volume: 127, Issue:2

    Topics: Animals; Antimalarials; Disease Models, Animal; Drug Stability; Female; Humans; Malaria; Mice; Microsomes, Liver; Plasmodium falciparum; Plasmodium yoelii; Quinolones; Rats; Structure-Activity Relationship

2011
Increased prevalence of the pfdhfr/phdhps quintuple mutant and rapid emergence of pfdhps resistance mutations at codons 581 and 613 in Kisumu, Kenya.
    Malaria journal, 2010, Nov-24, Volume: 9

    Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chloroquine; Codon; Cross-Sectional Studies; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Folic Acid Antagonists; Genotype; Humans; Inhibitory Concentration 50; Kenya; Malaria; Mutation, Missense; Parasitic Sensitivity Tests; Plasmodium; Prevalence; Protozoan Proteins; Pyrimethamine; Quinolones; Sulfadoxine; Tetrahydrofolate Dehydrogenase

2010
Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).
    Journal of medicinal chemistry, 2012, Mar-08, Volume: 55, Issue:5

    Topics: Administration, Oral; Animals; Antimalarials; Crystallography, X-Ray; Drug Design; Electron Transport Complex III; Humans; In Vitro Techniques; Malaria; Male; Mice; Microsomes, Liver; Models, Molecular; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Quinolones; Quinone Reductases; Structure-Activity Relationship

2012
Identification, design and biological evaluation of heterocyclic quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).
    Journal of medicinal chemistry, 2012, Mar-08, Volume: 55, Issue:5

    Topics: Administration, Oral; Animals; Antimalarials; Atovaquone; Crystallography, X-Ray; Cytochromes b; Drug Design; Drug Resistance; Humans; Malaria; Male; Mice; Microsomes, Liver; Models, Molecular; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Pyridines; Quinolones; Quinone Reductases; Rats; Structure-Activity Relationship

2012
4(1H)-Quinolones with liver stage activity against Plasmodium berghei.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:1

    Topics: Animals; Antimalarials; Female; Genes, Reporter; Hep G2 Cells; Hepatocytes; Humans; Inhibitory Concentration 50; Kinetics; Liver; Luciferases; Malaria; Mice; Mice, Inbred BALB C; Organisms, Genetically Modified; Plasmodium berghei; Quinolones; Sporozoites

2013
Protein farnesyltransferase inhibitors exhibit potent antimalarial activity.
    Journal of medicinal chemistry, 2005, Jun-02, Volume: 48, Issue:11

    Topics: Alkyl and Aryl Transferases; Animals; Antimalarials; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Farnesyltranstransferase; Female; Humans; Malaria; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Plasmodium berghei; Plasmodium falciparum; Protein Prenylation; Quinolones; Rats; Structure-Activity Relationship

2005
Synthesis of quinolinyl chalcones and evaluation of their antimalarial activity.
    European journal of medicinal chemistry, 2001, Volume: 36, Issue:6

    Topics: Animals; Antimalarials; Chalcone; Drug Design; Drug Evaluation, Preclinical; Endopeptidases; Gas Chromatography-Mass Spectrometry; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Malaria; Male; Mice; Mice, Inbred BALB C; Plasmodium berghei; Plasmodium falciparum; Quinolones; Structure-Activity Relationship

2001
Fluoroquinolones for malaria: the newest kid on the block?
    Annals of internal medicine, 1989, Aug-15, Volume: 111, Issue:4

    Topics: Antimalarials; Drug Resistance; Drug Therapy, Combination; History, 20th Century; History, Ancient; Humans; Malaria; Molecular Structure; Norfloxacin; Quinolones

1989