Page last updated: 2024-08-17

carbostyril and Lung Neoplasms

carbostyril has been researched along with Lung Neoplasms in 59 studies

Research

Studies (59)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (5.08)	18.2507
2000's	19 (32.20)	29.6817
2010's	29 (49.15)	24.3611
2020's	8 (13.56)	2.80

Authors

Authors	Studies
Gilleran, J; Jabbour, SK; Jia, D; Langenfeld, E; Langenfeld, J; Mondal, A; Napoli, L; NeMoyer, R; Peng, Y; Roberge, J; Rongo, C; Syed, Z; Vora, M	1
Anh, DT; Dung, DTM; Dung, PTP; Hai, PT; Han, SB; Huy, LD; Jun, HW; Kang, JS; Kwon, JH; Nam, NH; Park, EJ; Tung, TT; Young Ji, A	1
Chen, CL; Chen, JJ; Chung, CL; Huang, CY; Lin, MW; Liu, PF; Tai, SB; Yang, JL; Yeh, YH	1
Herbert, KJ; Higgins, GS; Prevo, R; Puliyadi, R; Ramadan, K; Rodriguez-Berriguete, G; Ryan, A	1
Dang, TPT; Nguyen, PAT; Nguyen, TAT; Nguyen, TH; Nguyen, THT; Phung, NKP; Truong, TBN	1
Fernandez-Juarez, G; Gimenez-Moyano, S; Guerrero-Marquez, C; Martinez de la Cruz, P; Mielgo-Rubio, X; Shabaka, A	1
Gao, HY; Guo, H; Hu, Q; Liang, LJ; Rao, Y; Wang, GZ; Xie, DW; Yang, YQ; Yu, H; Zhao, Q; Zhou, GB	1
Chamni, S; Chanvorachote, P; Chaotham, C; Ecoy, GU; Prompetchara, E; Sumkhemthong, S; Suwanborirux, K; Taweecheep, P	1
Ahn, MJ; Cho, BC; Han, JY; Hong, MH; Kang, HN; Kim, DJ; Kim, EY; Kim, H; Kim, HR; Kim, J; Kim, SM; Kim, TM; Lee, CY; Lee, JG; Paik, S; Park, HJ; Pyo, KH; Shim, HS; Youn, HA; Yun, MR	1
Akizuki, N; Hanawa, T; Hayashi, S; Ishii, N; Kawano, Y; Komoda, M; Sakai, H	1
Batra, SK; Dhanasingh, I; Kanteti, R; Kaushik, G; Kindler, HL; Kulkarni, P; Mambetsariev, B; Mirzapoiazova, T; Nasser, MW; Ponnusamy, MP; Riehm, JJ; Salgia, R; Seshacharyulu, P; Wang, J	1
Augeri, DJ; Bommareddy, PK; Carayannopolous, MO; Chesson, CB; Dobias, NS; Goedken, M; Jabbour, SK; Jhawar, SR; Kerrigan, JE; Langenfeld, E; Langenfeld, J; Lee, MJ; Li, S; Malhotra, J; Marshall, S; Minerowicz, C; NeMoyer, R; Newman, JH; Sadimin, ET; Tarabichi, S; Zloza, A	1
Aboubakar Nana, F; Detry, B; Dupasquier, S; Feron, O; Ladjemi, MZ; Lecocq, M; Massion, PP; Ocak, S; Pilette, C; Sibille, Y	1
De Koning, L; De Wolf, J; Jaurand, MC; Jean, D; Le Pimpec-Barthes, F; Meiller, C; Montagne, F; Quetel, L; Tranchant, R; Zucman-Rossi, J	1
Day, AG; Elliott, BE; Ghaffari, A; Greer, PA; Hoskin, V; Kiefer, F; Madarnas, Y; Mewburn, J; Mullins, G; SenGupta, S; Turashvili, G; Varma, S	1
Birykov, MV; Komarova, ES; Kostyukevich, Y; Lukianov, DA; Nikolaev, E; Osterman, IA; Polshakov, VI; Sergiev, PV; Shiriaev, DI; Skvortsov, DA; Tashlitsky, VN; Zakalyukina, YV	1
Adil, MS; Alwhaibi, A; Artham, S; Somanath, PR; Verma, A	1
Chamni, S; Chanvorachote, P; Chaotham, C; Ecoy, GAU; Suwanborirux, K	1
Cho, BC; Kim, HR; Lim, SM; Shim, HS; Soo, RA	1
Khanna, C; Ren, L	1
Du, SS; Fan, L; Feng, JB; Liu, JX; Qi, XS; Su, X; Tian, M; Wang, CF; Wang, YY	1
Das, M; Frymoyer, A; Neal, JW; Padda, SK; Riess, JW; Wakelee, HA; Zhou, L	1
Cho, BC; Jang, KW; Kang, CW; Kang, HN; Kim, DJ; Kim, H; Kim, HR; Kim, JH; Kim, SM; Lim, SM; Moon, YW; Paik, S; Pyo, KH; Sohn, J; Yun, MR	1
Ayhan, A; Bulut, G; Çelik, H; Conn, EJ; Graham, GT; Han, J; Hayran, M; Hong, SH; Li, X; Minas, TZ; Özdemirli, M; Pauly, GT; Rudek, MA; Toretsky, JA; Üren, A	1
Alberts, SR; Allotey, LK; Barr Fritcher, EG; Barrett, MT; Borad, MJ; Chaiteerakij, R; Chen, G; Clark, KJ; Ding, X; Greipp, PT; Gustafson, MP; Kipp, BR; Knudson, RA; McNulty, MS; Miyabe, K; Mohamed, EA; Moser, CD; Ndzengue, A; Roberts, LR; Shaleh, HM; Torbenson, MS; Wang, S; Wang, Y; Zhou, J	1
Ahn, JS; Ahn, MJ; Ahn, S; Cho, BC; Choi, YL; Kim, HR; Kim, JH; Lee, JY; Lee, SH; Lim, SH; Park, K; Sun, JM	1
Fernández-Villar, A; Leiro-Fernández, V; Priegue Carrera, A	1
Bankovic, J; Dragoj, M; Milosevic, Z; Pesic, M; Stankovic, T; Tanic, N	1
Inoue, H; Kato, T; Matsuo, Y; Miyamoto, T; Nakamura, Y; Park, JH; Salgia, R; Zewde, M	1
Addison, CL; Bane, A; Filion, ML; Goffin, J; Gupta, A; Hao, D; Khomani, A; Laurie, SA; Leighl, NB; Levine, MN; Pond, GR; Seely, J	1
Ezell, SJ; Murugesan, S; Nadkarni, DH; Rayburn, ER; Velu, SE; Wang, F; Wang, W; Zhang, R	1
Le Moulec, S; Loriot, Y; Soria, JC	1
Li, M; Liu, A; Liu, B; Luo, X; Yu, H; Zheng, H	1
Gillissen, A; Häussermann, A	1
Estrada, L; Gonzalez, AL; Jiang, A; Massion, PP; Miller, AN; Ocak, S; Quaranta, V; Shyr, Y; Udyavar, AR; Yamashita, H; Yi, Y; Zou, Y	1
Beauchamp, EM; Bulut, G; Chen, K; Daar, I; Dakshanamurthy, S; Glasgow, E; Hong, SH; Khanna, C; Kosturko, GW; Lee, HS; Rahim, S; Toretsky, JA; Uren, A	1
Bernhard, JC; De Clermont, H; Gross-Goupil, M; Quivy, A; Ravaud, A; Roca, S	1
Choo, SP; Chow, PK; Chung, AY; Huynh, H; Linnartz, R; Ong, HS; Ong, R; Shi, MM; Soo, KC; Tai, WM	1
Busceti, MT; Caraglia, M; Falcone, D; Fratto, D; Gallelli, L; Maselli, R; Pelaia, G; Renda, T; Savino, R; Terracciano, R; Vatrella, A	1
Sánchez De Cos Escuín, J	1
Smit, EF	1
Nishiyama, M; Tahara, E; Tsuruo, T; Yasui, W	1
Adjei, AA; Bruzek, L; Erlichman, C; Geyer, S; Hanson, LJ; Hillman, S; Kaufmann, SH; Marks, RS; Mauer, A; Vokes, EE; Wright, JJ	1
End, DW; Gunning, WT; Kramer, PM; Lubet, RA; Pereira, MA; Steele, VE; Wouters, W	1
Khuri, FR	1
Chao, JI; Hsu, TS; Kuo, PC	1
Heymach, JV; Johnson, BE	1
De Porre, PM; DeVore, RF; Heymach, JV; Jia, X; Johnson, BE; Johnson, DH; Khuri, FR; Richards, HM; Safran, H; Schlabach, LL; Yunus, F; Zhang, S	1
Allegranzi, B; Ciottoli, GB; Concia, E; Dionisio, P; Marchetti, M; Orticelli, G	1
Ito, T; Miyagi, Y; Udaka, N	1
Alyaqoub, FS; Gunning, WT; Kramer, PM; Lubet, RA; Pereira, MA; Steele, VE; Tao, L	2
Khuri, FR; Liu, X; Lonial, S; Qiu, Y; Sun, SY; Yue, P; Zou, W	1
Chao, JI; Chen, C; Chiu, SJ; Hsu, TS; Lee, PT; Liu, HF; Tsai, CC	1
Hamel, E; Kuo, SC; Lednicer, D; Lee, KH; Li, L; Lin, CM; Wang, HK; Wu, TS	1
Chang, JJ; Hamel, E; Juang, JP; Kuo, SC; Lednicer, D; Lee, HZ; Lin, CM; Lin, YT; Paull, KD; Wu, TS	1
Iki, K; Kido, A; Konishi, Y; Morishita, T; Motoyama, M; Takahama, M; Tamai, S; Tatsumi, K; Tsujiuchi, T; Tsutsumi, M	1
Ruffin, RE; Truong-Tran, AQ; Zalewski, PD	1
Aligiannis, N; Fokialakis, N; Magiatis, P; Mitaku, S; Sévenet, T; Tillequin, F	1

Reviews

7 review(s) available for carbostyril and Lung Neoplasms

Article	Year
Concomitant Acute Tubular Necrosis and Acute Interstitial Nephritis Induced by Tipifarnib in a Patient with Squamous Cell Carcinoma of the Lung. The American journal of the medical sciences, 2021, Volume: 362, Issue:1 Topics: Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Humans; Kidney Cortex Necrosis; Lung Neoplasms; Male; Nephritis, Interstitial; Quinolones	2021
Role of FGF receptors as an emerging therapeutic target in lung squamous cell carcinoma. Future oncology (London, England), 2013, Volume: 9, Issue:3 Topics: Alanine; Antineoplastic Agents; Benzimidazoles; Carcinoma, Squamous Cell; Gene Amplification; Humans; Lung Neoplasms; Molecular Targeted Therapy; Quinazolines; Quinolones; Receptors, Fibroblast Growth Factor; Signal Transduction; Triazines	2013
Role of ezrin in osteosarcoma metastasis. Advances in experimental medicine and biology, 2014, Volume: 804 Topics: Adamantane; Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Child; Cytoskeletal Proteins; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Molecular Targeted Therapy; Osteosarcoma; Phenols; Quinolines; Quinolones; Signal Transduction	2014
[Diseases of the lung and air passages 2010]. Deutsche medizinische Wochenschrift (1946), 2010, Volume: 135, Issue:25-26 Topics: Administration, Inhalation; Adrenergic beta-Agonists; Aminopyridines; Asthma; Benzamides; Cyclopropanes; Drug Therapy, Combination; Humans; Hypertension, Pulmonary; Indans; Lung Diseases; Lung Neoplasms; Neoplasm Staging; Phosphodiesterase 4 Inhibitors; Pneumonia, Bacterial; Practice Guidelines as Topic; Pulmonary Disease, Chronic Obstructive; Quinolones	2010
[New therapeutic targets and strategies in lung cancer]. Archivos de bronconeumologia, 2002, Volume: 38, Issue:8 Topics: Alkyl and Aryl Transferases; Angiogenesis Inhibitors; Antineoplastic Agents; Benzamides; Benzodiazepines; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Endothelial Growth Factors; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Erlotinib Hydrochloride; Farnesyltranstransferase; Gefitinib; Humans; Imatinib Mesylate; Imidazoles; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Lymphokines; Metalloendopeptidases; Multicenter Studies as Topic; Piperazines; Polyisoprenyl Phosphates; Protein-Tyrosine Kinases; Pyrimidines; Quinazolines; Quinolones; Randomized Controlled Trials as Topic; Receptor Protein-Tyrosine Kinases; Sesquiterpenes; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2002
Primary and secondary prevention of non-small-cell lung cancer: the SPORE Trials of Lung Cancer Prevention. Clinical lung cancer, 2003, Volume: 5 Suppl 1 Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Chemoprevention; Clinical Trials as Topic; Disease Progression; Epidermal Growth Factor; Gefitinib; Humans; Lung Neoplasms; Precancerous Conditions; Protein-Tyrosine Kinases; Quinazolines; Quinolones	2003
Farnesyl transferase inhibitors for patients with lung cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jun-15, Volume: 10, Issue:12 Pt 2 Topics: Alkyl and Aryl Transferases; Apoptosis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Clinical Trials as Topic; Farnesyltranstransferase; Humans; Imidazoles; Lung Neoplasms; Quinolones; Signal Transduction; Treatment Outcome	2004

Trials

7 trial(s) available for carbostyril and Lung Neoplasms

Article	Year
Dovitinib and erlotinib in patients with metastatic non-small cell lung cancer: A drug-drug interaction. Lung cancer (Amsterdam, Netherlands), 2015, Volume: 89, Issue:3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinoma, Non-Small-Cell Lung; Drug Interactions; Erlotinib Hydrochloride; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Neoplasm Metastasis; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Quinolones; Receptors, Vascular Endothelial Growth Factor; Retreatment; Treatment Outcome	2015
Efficacy and safety of dovitinib in pretreated patients with advanced squamous non-small cell lung cancer with FGFR1 amplification: A single-arm, phase 2 study. Cancer, 2016, Volume: 122, Issue:19 Topics: Aged; Aged, 80 and over; Benzimidazoles; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Follow-Up Studies; Gene Amplification; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Prognosis; Quinolones; Receptor, Fibroblast Growth Factor, Type 1; Survival Rate	2016
Efficacy of Double Bronchodilation (LABA+LAMA) in Patients with Chronic Obstructive Pulmonary Disease (COPD) and Lung Cancer. Archivos de bronconeumologia, 2016, Volume: 52, Issue:12 Topics: Adenocarcinoma; Adrenergic beta-2 Receptor Agonists; Aged; Bronchodilator Agents; Carcinoma, Squamous Cell; Delayed-Action Preparations; Female; Glycopyrrolate; Humans; Indans; Lung Neoplasms; Male; Middle Aged; Muscarinic Antagonists; Pilot Projects; Pneumonectomy; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Quinolones	2016
A phase II trial of dovitinib in previously-treated advanced pleural mesothelioma: The Ontario Clinical Oncology Group. Lung cancer (Amsterdam, Netherlands), 2017, Volume: 104 Topics: Aged; Angiogenesis Inducing Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Diffusion Magnetic Resonance Imaging; Disease Progression; Disease-Free Survival; Female; Humans; Lung Neoplasms; Male; Mesothelioma; Mesothelioma, Malignant; Middle Aged; Ontario; Pleural Neoplasms; Protein Kinase Inhibitors; Quinolones; Receptors, Fibroblast Growth Factor; Receptors, Vascular Endothelial Growth Factor	2017
Phase II study of the farnesyl transferase inhibitor R115777 in patients with advanced non-small-cell lung cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, May-01, Volume: 21, Issue:9 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Alkyl and Aryl Transferases; Anemia; Carcinoma, Non-Small-Cell Lung; Disease Progression; Farnesyltranstransferase; Female; Humans; Leukocytes, Mononuclear; Lung Neoplasms; Male; Middle Aged; Mouth Mucosa; Neutropenia; Quinolones; Survival	2003
Phase II study of the farnesyl transferase inhibitor R115777 in patients with sensitive relapse small-cell lung cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 2004, Volume: 15, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Alkyl and Aryl Transferases; Carcinoma, Small Cell; Disease-Free Survival; Farnesyltranstransferase; Female; Humans; Lung Neoplasms; Male; Middle Aged; Quinolones; Recurrence; Signal Transduction; Treatment Outcome	2004
Penetration of orally administered prulifloxacin into human lung tissue. Clinical pharmacokinetics, 2005, Volume: 44, Issue:12 Topics: Administration, Oral; Aged; Anti-Infective Agents; Dioxolanes; Female; Fluoroquinolones; Humans; Lung; Lung Neoplasms; Male; Middle Aged; Piperazines; Pneumonectomy; Quinolones	2005

Other Studies

45 other study(ies) available for carbostyril and Lung Neoplasms

Article	Year
Bone morphogenetic protein receptor 2 inhibition destabilizes microtubules promoting the activation of lysosomes and cell death of lung cancer cells. Cell communication and signaling : CCS, 2021, 09-25, Volume: 19, Issue:1 Topics: Bone Morphogenetic Protein Receptors, Type I; Bone Morphogenetic Protein Receptors, Type II; Cell Death; Cell Proliferation; Cell Survival; Humans; Imidazoles; Lung Neoplasms; Lysosomes; Microtubules; Naphthoquinones; Pyrazoles; Pyrimidines; Quinolones; RNA, Small Interfering; Signal Transduction	2021
Design, synthesis, and evaluation of novel (E)-N'-(3-allyl-2-hydroxy)benzylidene-2-(4-oxoquinazolin-3(4H)-yl)acetohydrazides as antitumor agents. Archiv der Pharmazie, 2022, Volume: 355, Issue:1 Topics: Antineoplastic Agents; Benzylidene Compounds; Cell Line, Tumor; Colonic Neoplasms; Fluorouracil; Humans; Hydrazines; Lung Neoplasms; Male; Molecular Docking Simulation; PC-3 Cells; Prostatic Neoplasms; Quinolones; Structure-Activity Relationship	2022
Fluoroquinolones Suppress TGF-β and PMA-Induced MMP-9 Production in Cancer Cells: Implications in Repurposing Quinolone Antibiotics for Cancer Treatment. International journal of molecular sciences, 2021, Oct-27, Volume: 22, Issue:21 Topics: A549 Cells; Anti-Bacterial Agents; Cell Line, Tumor; Cell Movement; Down-Regulation; Drug Repositioning; Epithelial-Mesenchymal Transition; Fluoroquinolones; Hep G2 Cells; Humans; Lung Neoplasms; Matrix Metalloproteinase 9; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Phosphorylcholine; Polymethacrylic Acids; Quinolones; Signal Transduction; Transforming Growth Factor beta	2021
Targeting TOPK sensitises tumour cells to radiation-induced damage by enhancing replication stress. Cell death and differentiation, 2021, Volume: 28, Issue:4 Topics: Animals; Apoptosis; cdc25 Phosphatases; Cell Line, Tumor; Checkpoint Kinase 1; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Mitogen-Activated Protein Kinase Kinases; Protein Kinase Inhibitors; Quinolones; Radiation Tolerance; Signal Transduction; Survival Rate; Xenograft Model Antitumor Assays	2021
Three quinolinone alkaloid - phenylpropanoid adducts from Natural product research, 2022, Volume: 36, Issue:15 Topics: Alkaloids; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Quinolones; Rutaceae	2022
Upregulation of wild-type p53 by small molecule-induced elevation of NQO1 in non-small cell lung cancer cells. Acta pharmacologica Sinica, 2022, Volume: 43, Issue:3 Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Lung Neoplasms; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Quinolones; Reactive Oxygen Species; RNA, Small Interfering; Tumor Suppressor Protein p53; Up-Regulation	2022
Jorunnamycin A Suppresses Stem-Like Phenotypes and Sensitizes Cisplatin-Induced Apoptosis in Cancer Stem-Like Cell-Enriched Spheroids of Human Lung Cancer Cells. Marine drugs, 2021, May-03, Volume: 19, Issue:5 Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Down-Regulation; Drug Synergism; Humans; Isoquinolines; Lung Neoplasms; Nanog Homeobox Protein; Neoplastic Stem Cells; Octamer Transcription Factor-3; Proto-Oncogene Proteins c-bcl-2; Quinolones; SOXB1 Transcription Factors; Spheroids, Cellular; Transcription Factors; Tumor Suppressor Protein p53; Xestospongia	2021
Co-clinical trials demonstrate predictive biomarkers for dovitinib, an FGFR inhibitor, in lung squamous cell carcinoma. Annals of oncology : official journal of the European Society for Medical Oncology, 2017, Jun-01, Volume: 28, Issue:6 Topics: Benzimidazoles; Biomarkers; Carcinoma, Squamous Cell; Clinical Trials as Topic; Exome Sequencing; Humans; Lung Neoplasms; Mutation; Quinolones; Receptors, Fibroblast Growth Factor; Signal Transduction	2017
Effects of a Rebamipide Mouthwash on Stomatitis Caused by Cancer Chemotherapy-Evaluation of the Efficacy by Patients Themselves. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2017, Aug-01, Volume: 137, Issue:8 Topics: Aged; Aged, 80 and over; Alanine; Antineoplastic Agents; Colorectal Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Mouthwashes; Quinolones; Rectal Neoplasms; Stomatitis; Treatment Outcome	2017
Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma. Cancer biology & therapy, 2018, 04-03, Volume: 19, Issue:4 Topics: Animals; Benzamides; Carcinoma, Pancreatic Ductal; Cell Adhesion; Cell Culture Techniques; Cell Line, Tumor; Cell Movement; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Mice; Mice, Transgenic; Neoplasms, Experimental; Pancreatic Neoplasms; Phosphorylation; Pleural Neoplasms; Proto-Oncogene Proteins p21(ras); Pyrazines; Quinolones; Sulfonamides; Sulfones	2018
Novel bone morphogenetic protein receptor inhibitor JL5 suppresses tumor cell survival signaling and induces regression of human lung cancer. Oncogene, 2018, Volume: 37, Issue:27 Topics: A549 Cells; Adoptive Transfer; Animals; Antineoplastic Agents; Bone Morphogenetic Protein Receptors; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Humans; Inhibitor of Differentiation Protein 1; Lung Neoplasms; MAP Kinase Kinase Kinases; Mice; Mice, Inbred NOD; Mice, SCID; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Quinolones; Signal Transduction; Tumor Microenvironment; Xenograft Model Antitumor Assays	2018
Therapeutic Potential of Focal Adhesion Kinase Inhibition in Small Cell Lung Cancer. Molecular cancer therapeutics, 2019, Volume: 18, Issue:1 Topics: Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Focal Adhesion Kinase 1; Humans; Lung Neoplasms; Phosphorylation; Protein Kinase Inhibitors; Quinolones; RNA, Small Interfering; Small Cell Lung Carcinoma; Sulfones	2019
Assessment of signaling pathway inhibitors and identification of predictive biomarkers in malignant pleural mesothelioma. Lung cancer (Amsterdam, Netherlands), 2018, Volume: 126 Topics: Antineoplastic Agents; Apoptosis; Benzamides; Biomarkers, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mesothelioma; Phenols; Pleural Neoplasms; Pyrazines; Quinolones; RNA Interference; Signal Transduction; Sulfonamides; Tumor Cells, Cultured; Verteporfin	2018
Intravital imaging reveals systemic ezrin inhibition impedes cancer cell migration and lymph node metastasis in breast cancer. Breast cancer research : BCR, 2019, 01-24, Volume: 21, Issue:1 Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cohort Studies; Cytoskeletal Proteins; Disease Models, Animal; Female; Genes, Reporter; Humans; Intravital Microscopy; Lung; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Neoplasm Recurrence, Local; Phenols; Quinolones; Tissue Array Analysis	2019
Nybomycin-producing Streptomyces isolated from carpenter ant Camponotus vagus. Biochimie, 2019, Volume: 160 Topics: Animals; Anti-Bacterial Agents; Ants; Cell Survival; Cells, Cultured; DNA, Bacterial; Escherichia coli; Fibroblasts; Humans; Lung Neoplasms; Phylogeny; Quinolones; RNA, Ribosomal, 16S; Streptomyces	2019
Nodal pathway activation due to Akt1 suppression is a molecular switch for prostate cancer cell epithelial-to-mesenchymal transition and metastasis. Biochemical pharmacology, 2019, Volume: 168 Topics: Animals; Benzodioxoles; Cell Movement; Cell Survival; Epithelial-Mesenchymal Transition; Forkhead Box Protein O3; Gene Silencing; Humans; Imidazoles; Lung Neoplasms; Male; Mice; Mice, Nude; Neoplasm Metastasis; Nodal Protein; PC-3 Cells; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Pyridines; Quinolones; Tumor Burden; Xenograft Model Antitumor Assays	2019
Jorunnamycin A from Journal of natural products, 2019, 07-26, Volume: 82, Issue:7 Topics: Animals; Anoikis; Cell Division; Cell Line, Tumor; Down-Regulation; Epithelial-Mesenchymal Transition; Humans; Isoquinolines; Lung Neoplasms; Proto-Oncogene Proteins c-bcl-2; Quinolones; Xestospongia	2019
Radiosensitizing effect of schinifoline from Zanthoxylum schinifolium Sieb et Zucc on human non-small cell lung cancer A549 cells: a preliminary in vitro investigation. Molecules (Basel, Switzerland), 2014, Dec-01, Volume: 19, Issue:12 Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Gamma Rays; Humans; Lung Neoplasms; Quinolones; Radiation-Sensitizing Agents; Radiation, Ionizing; Sesquiterpenes; Tumor Stem Cell Assay; Zanthoxylum	2014
Antitumor Activity and Acquired Resistance Mechanism of Dovitinib (TKI258) in RET-Rearranged Lung Adenocarcinoma. Molecular cancer therapeutics, 2015, Volume: 14, Issue:10 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Apoptosis; Benzimidazoles; Catalytic Domain; Cell Cycle Checkpoints; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme Activation; HEK293 Cells; Humans; Inhibitory Concentration 50; Lung Neoplasms; Mice, Nude; Models, Molecular; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-ret; Quinolones; src-Family Kinases; Tumor Burden; Xenograft Model Antitumor Assays	2015
Ezrin Inhibition Up-regulates Stress Response Gene Expression. The Journal of biological chemistry, 2016, Jun-17, Volume: 291, Issue:25 Topics: Adamantane; Animals; Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cytoskeletal Proteins; Dogs; Female; Half-Life; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Osteosarcoma; Phenols; Quinolines; Quinolones; Stress, Physiological; Transcriptome; Xenograft Model Antitumor Assays	2016
Antitumor effect of FGFR inhibitors on a novel cholangiocarcinoma patient derived xenograft mouse model endogenously expressing an FGFR2-CCDC6 fusion protein. Cancer letters, 2016, 09-28, Volume: 380, Issue:1 Topics: Animals; Antineoplastic Agents; Apoptosis; Benzimidazoles; Bile Duct Neoplasms; Cell Proliferation; Cholangiocarcinoma; Cytoskeletal Proteins; Gene Fusion; Humans; Imidazoles; Interleukin Receptor Common gamma Subunit; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Phenylurea Compounds; Pyridazines; Pyrimidines; Quinolones; Receptor, Fibroblast Growth Factor, Type 2; Signal Transduction; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays	2016
Targeting CXCR4 and FAK reverses doxorubicin resistance and suppresses invasion in non-small cell lung carcinoma. Cellular oncology (Dordrecht), 2017, Volume: 40, Issue:1 Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; Benzylamines; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Doxorubicin; Drug Resistance, Neoplasm; Focal Adhesion Kinase 1; Gene Expression Profiling; Humans; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Neoplasm Invasiveness; Quinolones; Real-Time Polymerase Chain Reaction; Receptors, CXCR4; Sulfones; Transcriptome	2017
TOPK (T-LAK cell-originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer. Cancer science, 2017, Volume: 108, Issue:3 Topics: Cell Proliferation; Forkhead Box Protein M1; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinase Kinases; Neoplastic Stem Cells; Quinolones; RNA Interference; RNA, Small Interfering; Small Cell Lung Carcinoma; Spheroids, Cellular; Thiophenes; Thy-1 Antigens; Tumor Cells, Cultured	2017
Synthesis and in vitro anti-lung cancer activity of novel 1, 3, 4, 8-tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-one alkaloid analogs. Medicinal chemistry (Shariqah (United Arab Emirates)), 2009, Volume: 5, Issue:3 Topics: Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Evaluation, Preclinical; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Quinolones	2009
[Targeting KRAS pathway in NSCLC therapy]. Bulletin du cancer, 2009, Volume: 96 Suppl Topics: Animals; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Non-Small-Cell Lung; Farnesyltranstransferase; Genes, ras; Humans; Lung Neoplasms; Mice; Mitogen-Activated Protein Kinase Kinases; Mutation; Neoplasm Proteins; Niacinamide; Phenylurea Compounds; Piperidines; Pyridines; Quinolones; raf Kinases; ras Proteins; Sorafenib	2009
Ras homologue enriched in brain is a critical target of farnesyltransferase inhibitors in non-small cell lung cancer cells. Cancer letters, 2010, Nov-01, Volume: 297, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Farnesyltranstransferase; Humans; Lung Neoplasms; Mechanistic Target of Rapamycin Complex 1; Monomeric GTP-Binding Proteins; Multiprotein Complexes; Mutation; Neuropeptides; Phosphorylation; Piperidines; Prenylation; Proteins; Pyridines; Quinolones; Ras Homolog Enriched in Brain Protein; Ribosomal Protein S6; RNA Interference; RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases; Transcription Factors; Transfection	2010
DNA copy number aberrations in small-cell lung cancer reveal activation of the focal adhesion pathway. Oncogene, 2010, Dec-02, Volume: 29, Issue:48 Topics: Carcinoma, Small Cell; Cell Adhesion; Cell Line, Tumor; Comparative Genomic Hybridization; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Gene Dosage; Humans; Lung Neoplasms; Quinolones; Sulfones	2010
Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells. Oncogene, 2012, Jan-19, Volume: 31, Issue:3 Topics: Actins; Adamantane; Animals; Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cytoskeletal Proteins; Female; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Organ Culture Techniques; Osteosarcoma; Phenols; Phosphorylation; Quinolines; Quinolones; Surface Plasmon Resonance; Xenopus; Zebrafish	2012
Efficacy of re-challenging metastatic renal cell carcinoma with mTOR inhibitors. Acta oncologica (Stockholm, Sweden), 2011, Volume: 50, Issue:7 Topics: Antineoplastic Agents; Benzimidazoles; Carcinoma, Renal Cell; Everolimus; Humans; Indoles; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pyrroles; Quinolones; Sirolimus; Sunitinib; TOR Serine-Threonine Kinases	2011
Dovitinib demonstrates antitumor and antimetastatic activities in xenograft models of hepatocellular carcinoma. Journal of hepatology, 2012, Volume: 56, Issue:3 Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzimidazoles; Bevacizumab; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Division; Cell Line, Tumor; Disease Models, Animal; G2 Phase; Humans; Liver Neoplasms; Lung Neoplasms; Mice; Mice, SCID; Quinolones; Survival Rate; Xenograft Model Antitumor Assays	2012
Effects of statins and farnesyl transferase inhibitors on ERK phosphorylation, apoptosis and cell viability in non-small lung cancer cells. Cell proliferation, 2012, Volume: 45, Issue:6 Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Line, Tumor; Cell Survival; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Farnesyltranstransferase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lung; Lung Neoplasms; MAP Kinase Signaling System; Phosphorylation; Quinolones; Simvastatin	2012
[New data presented at ASCO 2002 concerning small cell bronchial cancer]. Revue de pneumologie clinique, 2002, Volume: 58, Issue:5 Pt 2 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Carboplatin; Carcinoma, Small Cell; Cisplatin; Deoxycytidine; Etoposide; Gemcitabine; Humans; Imatinib Mesylate; Lung Neoplasms; Piperazines; Prognosis; Pyrimidines; Quinolones; Smoking; Smoking Prevention; Survival Analysis; Treatment Outcome	2002
Molecular targeting therapy for cancer: the Twelfth International Symposium of the Hiroshima Cancer Seminar, November 2002. Cancer science, 2003, Volume: 94, Issue:2 Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clinical Trials as Topic; DNA Repair; Drug Delivery Systems; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; ErbB Receptors; Farnesyltranstransferase; Gene Expression Profiling; Humans; Lung Neoplasms; Mice; Mice, SCID; Neoplasm Proteins; Neoplasms; Quinolones; Xenograft Model Antitumor Assays	2003
Chemoprevention of benzo(a)pyrene-induced lung tumors in mice by the farnesyltransferase inhibitor R115777. Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:5 Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Benzo(a)pyrene; Chemoprevention; Enzyme Inhibitors; Female; Lung Neoplasms; Mice; Mice, Inbred A; Quinolones	2003
Down-regulation of survivin in nitric oxide-induced cell growth inhibition and apoptosis of the human lung carcinoma cells. The Journal of biological chemistry, 2004, May-07, Volume: 279, Issue:19 Topics: Antineoplastic Agents; Apoptosis; Arsenites; Benzazepines; Blotting, Western; Carcinoma; CDC2 Protein Kinase; Cell Cycle; Cell Division; Cell Line, Tumor; Cisplatin; Dose-Response Relationship, Drug; Down-Regulation; Fluorescent Antibody Technique, Indirect; G2 Phase; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Indoles; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Male; MAP Kinase Signaling System; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinases; Mitosis; Neoplasm Proteins; Nitric Oxide; Nitroprusside; p38 Mitogen-Activated Protein Kinases; Penicillamine; Purines; Pyridines; Quercetin; Quinolones; Quinones; Reverse Transcriptase Polymerase Chain Reaction; Survivin; Time Factors; Transfection	2004
Connexin expression in mouse lung tumor. Cancer letters, 2007, Feb-08, Volume: 246, Issue:1-2 Topics: 4-Nitroquinoline-1-oxide; Adenocarcinoma; Animals; Blotting, Western; Connexin 26; Connexin 43; Connexins; Gap Junction alpha-4 Protein; Gap Junction alpha-5 Protein; Gap Junction beta-1 Protein; Gene Expression Regulation, Neoplastic; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred A; Phosphorylation; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2007
Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (ZarnestraMT). Carcinogenesis, 2006, Volume: 27, Issue:12 Topics: Animals; Anti-Inflammatory Agents; Budesonide; Disease Models, Animal; DNA Methylation; Drug Therapy, Combination; Female; Lung Neoplasms; Mice; Mice, Inbred A; Quinolones	2006
Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (Zarnestra MT). Carcinogenesis, 2007, Volume: 28, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Budesonide; Chemoprevention; Disease Models, Animal; DNA Methylation; Drug Therapy, Combination; Female; Lung Neoplasms; Mice; Mice, Inbred A; Quinolones; Urethane	2007
The farnesyltransferase inhibitor R115777 up-regulates the expression of death receptor 5 and enhances TRAIL-induced apoptosis in human lung cancer cells. Cancer research, 2007, May-15, Volume: 67, Issue:10 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Growth Processes; Cell Line, Tumor; Drug Synergism; Farnesyltranstransferase; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Quinolones; Receptors, TNF-Related Apoptosis-Inducing Ligand; RNA, Messenger; RNA, Small Interfering; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation	2007
7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel synthetic compound induces lung carcinoma cell death associated with inhibiting ERK and CDC2 phosphorylation via a p53-independent pathway. Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:5 Topics: Antineoplastic Agents; Apoptosis; Carcinoma; CDC2 Protein Kinase; Cell Count; Cell Cycle; Cell Death; Cell Division; Cell Line, Tumor; Cell Proliferation; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Humans; Lung Neoplasms; Membrane Potentials; Mitochondrial Membranes; Mitogen-Activated Protein Kinases; Phosphorylation; Quinolones; Quinones; Signal Transduction; Tumor Suppressor Protein p53	2008
Antitumor agents. 150. 2',3',4',5',5,6,7-substituted 2-phenyl-4-quinolones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization. Journal of medicinal chemistry, 1994, Apr-15, Volume: 37, Issue:8 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Small Cell; Cattle; Cell Division; Central Nervous System Neoplasms; Colonic Neoplasms; Female; Humans; Leukemia; Lung Neoplasms; Molecular Structure; Polymers; Quinolones; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured	1994
Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. Journal of medicinal chemistry, 1993, Apr-30, Volume: 36, Issue:9 Topics: Animals; Antineoplastic Agents; Humans; Intestinal Neoplasms; Leukemia L1210; Leukemia P388; Lung Neoplasms; Melanoma; Mice; Molecular Structure; Nasopharyngeal Neoplasms; Quinolines; Quinolones; Software; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured	1993
Inhibition of spontaneous rat osteosarcoma lung metastasis by 3S-[4-(N-hydroxyamino)-2R-isobutylsuccinyl]amino-1-methoxy-3,4-dihydroc arbostyril, a novel matrix metalloproteinase inhibitor. Japanese journal of cancer research : Gann, 1999, Volume: 90, Issue:3 Topics: Administration, Oral; Animals; Body Weight; Collagenases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme Precursors; Gelatinases; Lung Neoplasms; Male; Matrix Metalloproteinase 3; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Molecular Weight; Neoplasm Transplantation; Organ Size; Osteosarcoma; Quinolones; Rats; Rats, Inbred F344; RNA, Messenger; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2	1999
Visualization of labile zinc and its role in apoptosis of primary airway epithelial cells and cell lines. American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 279, Issue:6 Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; Apoptosis; Bronchi; Butyrates; Caspase 3; Caspases; Chelating Agents; Coumarins; Drug Synergism; Enzyme Activation; Epithelial Cells; Ethylenediamines; Fluorescent Dyes; Humans; Hydrogen Peroxide; Lung Neoplasms; Microscopy, Electron; Microscopy, Fluorescence; Oligopeptides; Oxidants; Pulmonary Alveoli; Quinolones; Respiratory Mucosa; Sheep; Swine; Tosyl Compounds; Trachea; Tumor Cells, Cultured; Zinc	2000
Furomegistines I and II, two furanopyridine alkaloids from the bark of Sarcomelicope megistophylla. Phytochemistry, 2001, Volume: 57, Issue:4 Topics: Alkaloids; Biological Factors; Colonic Neoplasms; Furans; Humans; Inhibitory Concentration 50; Lung Neoplasms; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Plant Stems; Pyridines; Quinolones; Rosales; Trees; Tumor Cells, Cultured	2001