Page last updated: 2024-08-17

carbostyril and Dry Eye

carbostyril has been researched along with Dry Eye in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (3.57)29.6817
2010's26 (92.86)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Choi, CY; Chung, SH; Chung, TY; Eom, Y; Hyon, JY; Kim, HK; Kim, HM; Kim, JY; Kim, MK; Ko, BY; Lee, HK; Lee, JS; Seo, KY; Song, JS; Yoon, KC1
Dogru, M; Kojima, T; Nakamura, S; Simsek, C; Tsubota, K1
Alfuraih, S; Barbarino, A; Shamloo, K; Sharma, A1
Fukagawa, K; Iwasaki, M; Okano, T; Saga, M; Sakata, M; Seika, D; Shimazaki, J1
Fujimoto, C; Igarashi, T; Kobayashi, M; Suzuki, H; Takahashi, H; Yaguchi, C1
Aoki, K; Dogru, M; Higa, K; Igarashi, A; Kojima, T; Shimazaki, J; Shimizu, T; Simsek, C; Tsubota, K1
Ji, YW; Kang, HG; Kim, HC; Lee, HK; Moon, I; Noh, H; Song, JS; Yeo, A1
Georgiev, GA; Yokoi, N1
Watanabe, H1
Hori, Y1
Fu, R; Jiang, Y; Zhang, J; Zhou, J1
Haruta, J; Kimura, K; Morita, Y; Orita, T; Sonoda, KH; Takeji, Y1
Awamura, S; Kinoshita, S; Nakamichi, N; Oshiden, K; Suzuki, H; Yokoi, N3
Inoue, Y; Koh, S; Maeda, N; Nishida, K; Sugmimoto, T1
Ibrahim, OM; Ishida, S; Kawakita, T; Kojima, T; Nagata, T; Ohguchi, T; Satake, Y; Shimazaki, J; Shimizu, T; Shirasawa, T; Tsubota, K1
Dogru, M; Ishida, R; Kaido, M; Tsubota, K1
Messmer, EM1
Fukui, M; Kamoi, M; Kawakita, T; Mukai, S; Ogawa, Y; Saijo-Ban, Y; Simmura, S; Tsubota, K; Yaguchi, S; Yamane, M1
Igarashi, A; Kamiya, K; Kobashi, H; Shimizu, K1
Maeda, Y; Matsumiya, W; Nagai, T; Nakamura, M; Otsuka, K; Ueda, K1
Fujimoto, C; Fujita, M; Igarashi, T; Kobayashi, M; Nakano, Y; Suzuki, H; Takahashi, H; Yamada, Y1
Akiyama-Fukuda, R; Usui, T; Yamagami, S; Yoshida, T1
Ding, J; Kam, WR; Liu, Y; Sullivan, DA1
Bielory, BP; Bielory, L; O'Brien, TP; Perez, VL; Shah, SP1
Hiratsuka, Y; Kawashima, M; Shigeyasu, C; Suwaki, K; Tsubota, K; Uchino, M; Yamada, M; Yokoi, N1
Dubois, D1

Reviews

5 review(s) available for carbostyril and Dry Eye

ArticleYear
Tear Film-Oriented Diagnosis and Tear Film-Oriented Therapy for Dry Eye Based on Tear Film Dynamics.
    Investigative ophthalmology & visual science, 2018, 11-01, Volume: 59, Issue:14

    Topics: Alanine; Antioxidants; Dry Eye Syndromes; Humans; Japan; Mucins; Ophthalmic Solutions; Polyphosphates; Quinolones; Tears; Uracil Nucleotides; Wettability

2018
Medical Treatment for Dry Eye in Japan.
    Investigative ophthalmology & visual science, 2018, 11-01, Volume: 59, Issue:14

    Topics: Alanine; Dry Eye Syndromes; Humans; Japan; Lubricant Eye Drops; Polyphosphates; Quinolones; Tears; Uracil Nucleotides

2018
Secreted Mucins on the Ocular Surface.
    Investigative ophthalmology & visual science, 2018, 11-01, Volume: 59, Issue:14

    Topics: Alanine; Conjunctiva; Dry Eye Syndromes; Goblet Cells; Humans; Mucin 5AC; Ophthalmic Solutions; Polyphosphates; Quinolones; Uracil Nucleotides

2018
Emerging therapeutics for ocular surface disease.
    Current opinion in allergy and clinical immunology, 2016, Volume: 16, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Cytokines; Dry Eye Syndromes; Eye; Glucocorticoids; Humans; Hypersensitivity; Immunoglobulin E; Immunotherapy; Inflammation; Leukotriene Antagonists; Quinolones; Th1-Th2 Balance

2016
Toxicology and overdose of atypical antipsychotic medications in children: does newer necessarily mean safer?
    Current opinion in pediatrics, 2005, Volume: 17, Issue:2

    Topics: Antipsychotic Agents; Aripiprazole; Basal Ganglia Diseases; Benzodiazepines; Cardiomyopathies; Child; Clozapine; Diabetes Mellitus; Dibenzothiazepines; Drug Interactions; Drug Overdose; Dry Eye Syndromes; Humans; Hyperlipidemias; Hypotension; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Seizures; Thiazoles

2005

Trials

6 trial(s) available for carbostyril and Dry Eye

ArticleYear
Efficacy and safety of 1% and 2% rebamipide clear solution in dry eye disease: a multicenter randomized trial.
    BMC ophthalmology, 2023, Aug-03, Volume: 23, Issue:1

    Topics: Adult; Alanine; Dry Eye Syndromes; Humans; Middle Aged; Ophthalmic Solutions; Quinolones; Tears

2023
A Prospective, Randomized Trial of Two Mucin Secretogogues for the Treatment of Dry Eye Syndrome in Office Workers.
    Scientific reports, 2017, 11-09, Volume: 7, Issue:1

    Topics: Adult; Alanine; Conjunctiva; Dry Eye Syndromes; Female; Humans; Male; Middle Aged; Occupational Diseases; Polyphosphates; Prospective Studies; Quality of Life; Quinolones; Sclera; Secretagogues; Surveys and Questionnaires; Treatment Outcome; Uracil Nucleotides

2017
A randomized, multicenter phase 3 study comparing 2% rebamipide (OPC-12759) with 0.1% sodium hyaluronate in the treatment of dry eye.
    Ophthalmology, 2013, Volume: 120, Issue:6

    Topics: Adult; Aged; Alanine; Anti-Ulcer Agents; Coloring Agents; Conjunctiva; Dry Eye Syndromes; Female; Fluorophotometry; Humans; Hyaluronic Acid; Lissamine Green Dyes; Male; Middle Aged; Ophthalmic Solutions; Quinolones; Tears; Treatment Outcome; Viscosupplements; Visual Acuity; Young Adult

2013
Effect of Rebamipide Ophthalmic Suspension on Intraocular Light Scattering for Dry Eye After Corneal Refractive Surgery.
    Cornea, 2015, Volume: 34, Issue:8

    Topics: Administration, Topical; Adult; Alanine; Anti-Ulcer Agents; Dry Eye Syndromes; Female; Humans; Keratomileusis, Laser In Situ; Lasers, Excimer; Light; Male; Middle Aged; Myopia; Postoperative Complications; Prospective Studies; Quinolones; Scattering, Radiation; Suspensions; Tears; Young Adult

2015
Improvements in Signs and Symptoms of Dry Eye after Instillation of 2% Rebamipide.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2015, Volume: 82, Issue:5

    Topics: Alanine; Dry Eye Syndromes; Female; Humans; Male; Ophthalmic Solutions; Quinolones; Treatment Outcome

2015
Rebamipide (OPC-12759) in the treatment of dry eye: a randomized, double-masked, multicenter, placebo-controlled phase II study.
    Ophthalmology, 2012, Volume: 119, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Antioxidants; Coloring Agents; Dose-Response Relationship, Drug; Double-Blind Method; Dry Eye Syndromes; Enzyme Inhibitors; Female; Fluorescein; Fluorophotometry; Humans; Lissamine Green Dyes; Male; Middle Aged; Ophthalmic Solutions; Quinolones; Treatment Outcome; Young Adult

2012

Other Studies

17 other study(ies) available for carbostyril and Dry Eye

ArticleYear
The Effects of Rebamipide 2% Ophthalmic Solution Application on Murine Subbasal Corneal Nerves After Environmental Dry Eye Stress.
    International journal of molecular sciences, 2019, Aug-18, Volume: 20, Issue:16

    Topics: Alanine; Animals; Anti-Inflammatory Agents; Cornea; Dry Eye Syndromes; Male; Mice; Mice, Inbred BALB C; Neuroprotective Agents; Peripheral Nerves; Quinolones

2019
Graft Versus Host Disease-Associated Dry Eye: Role of Ocular Surface Mucins and the Effect of Rebamipide, a Mucin Secretagogue.
    Investigative ophthalmology & visual science, 2019, 11-01, Volume: 60, Issue:14

    Topics: Administration, Ophthalmic; Alanine; Animals; Antioxidants; Bone Marrow Transplantation; CA-125 Antigen; Disease Models, Animal; Dry Eye Syndromes; Enzyme-Linked Immunosorbent Assay; Eye Proteins; Female; Goblet Cells; Graft vs Host Disease; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Mucin 5AC; Mucin-1; Mucin-4; Mucins; Periodic Acid-Schiff Reaction; Quinolones; Real-Time Polymerase Chain Reaction; Tears; Transplantation, Homologous

2019
Efficacy of Rebamipide Instillation for Contact Lens Discomfort With Dry Eye.
    Eye & contact lens, 2018, Volume: 44 Suppl 2

    Topics: Adult; Alanine; Antioxidants; Contact Lenses, Hydrophilic; Cytokines; Dry Eye Syndromes; Female; Humans; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Quinolones; Tears; Young Adult

2018
The Role of 2% Rebamipide Eye Drops Related to Conjunctival Differentiation in Superoxide Dismutase-1 (Sod1) Knockout Mice.
    Investigative ophthalmology & visual science, 2018, 03-01, Volume: 59, Issue:3

    Topics: Alanine; Animals; Antioxidants; Biomarkers; Cell Differentiation; Conjunctiva; Disease Models, Animal; Dry Eye Syndromes; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Ophthalmic Solutions; Quinolones; RNA, Messenger; Superoxide Dismutase-1; Tears

2018
Comparison of Ocular Surface Mucin Expression After Topical Ophthalmic Drug Administration in Dry Eye-Induced Mouse Model.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2018, Volume: 34, Issue:9

    Topics: Administration, Topical; Alanine; Animals; Anti-Inflammatory Agents; Cyclosporine; Disease Models, Animal; Dry Eye Syndromes; Epithelium, Corneal; Female; Inflammation; Mice; Mice, Inbred C57BL; Mucins; Ophthalmic Solutions; Polyphosphates; Quinolones; Uracil Nucleotides

2018
Rebamipide ophthalmic solution modulates the ratio of T helper cell 17/regulatory T cells in dry eye disease mice.
    Molecular medicine reports, 2019, Volume: 19, Issue:5

    Topics: Alanine; Animals; Conjunctiva; Cornea; Cytokines; Disease Models, Animal; Dry Eye Syndromes; Female; Lacrimal Apparatus; Mice; Mice, Inbred C57BL; Ophthalmic Solutions; Quinolones; T-Lymphocytes, Regulatory; Th17 Cells

2019
Protection of human corneal epithelial cells from TNF-α-induced disruption of barrier function by rebamipide.
    Investigative ophthalmology & visual science, 2013, Apr-17, Volume: 54, Issue:4

    Topics: Adherens Junctions; Alanine; Animals; Antioxidants; beta Catenin; Cadherins; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Dry Eye Syndromes; Electric Impedance; Epithelium, Corneal; Fluorescent Antibody Technique, Indirect; Humans; I-kappa B Proteins; Immunoblotting; Male; NF-kappa B; NF-KappaB Inhibitor alpha; Occludin; Ophthalmic Solutions; Phosphorylation; Quinolones; Rats; Rats, Sprague-Dawley; Tight Junctions; Tumor Necrosis Factor-alpha; Wound Healing; Zonula Occludens-1 Protein

2013
Effect of rebamipide ophthalmic suspension on optical quality in the short break-up time type of dry eye.
    Cornea, 2013, Volume: 32, Issue:9

    Topics: Aberrometry; Adult; Aged; Aged, 80 and over; Alanine; Antioxidants; Corneal Topography; Corneal Wavefront Aberration; Dry Eye Syndromes; Female; Humans; Male; Middle Aged; Ophthalmic Solutions; Quinolones; Tears; Visual Acuity

2013
The effects of 2% rebamipide ophthalmic solution on the tear functions and ocular surface of the superoxide dismutase-1 (sod1) knockout mice.
    Investigative ophthalmology & visual science, 2013, Nov-21, Volume: 54, Issue:12

    Topics: Alanine; Animals; Conjunctiva; Disease Models, Animal; Dose-Response Relationship, Drug; Dry Eye Syndromes; Enzyme Inhibitors; Male; Mice; Mice, Knockout; Ophthalmic Solutions; Quinolones; Superoxide Dismutase; Superoxide Dismutase-1; Tears

2013
A multicenter, open-label, 52-week study of 2% rebamipide (OPC-12759) ophthalmic suspension in patients with dry eye.
    American journal of ophthalmology, 2014, Volume: 157, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Antioxidants; Cornea; Dry Eye Syndromes; Female; Fluorescein; Humans; Male; Middle Aged; Quinolones; Staining and Labeling; Suspensions; Tears; Time Factors; Treatment Outcome; Visual Acuity; Young Adult

2014
Short-term effects of instillation of a rebamipide suspension on visual function.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2014, Volume: 30, Issue:4

    Topics: Adult; Alanine; Dry Eye Syndromes; Female; Humans; Instillation, Drug; Male; Middle Aged; Ophthalmic Solutions; Quinolones; Suspensions; Tears; Vision, Ocular; Visual Acuity

2014
[New therapeutic options for dry eye].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2014, Volume: 111, Issue:5

    Topics: Alanine; Animals; Anti-Ulcer Agents; Cornea; Disease Models, Animal; Dry Eye Syndromes; Female; Humans; Hyaluronic Acid; Hydroxamic Acids; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Lymphocyte Function-Associated Antigen-1; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Molecular Targeted Therapy; Ophthalmic Solutions; Polyphosphates; Quinolones; Sulfonamides; Uracil Nucleotides; Viscosupplements

2014
Long-term rebamipide and diquafosol in two cases of immune-mediated dry eye.
    Optometry and vision science : official publication of the American Academy of Optometry, 2015, Volume: 92, Issue:4 Suppl 1

    Topics: Administration, Topical; Aged; Alanine; Drug Therapy, Combination; Dry Eye Syndromes; Enzyme Inhibitors; Female; Fluorescein; Fluorescent Dyes; Follow-Up Studies; Graft vs Host Disease; Humans; Middle Aged; Ophthalmic Solutions; Pemphigoid, Benign Mucous Membrane; Polyphosphates; Purinergic P2Y Receptor Agonists; Quinolones; Treatment Outcome; Uracil Nucleotides; Visual Acuity

2015
Effectiveness and relevant factors of 2% rebamipide ophthalmic suspension treatment in dry eye.
    BMC ophthalmology, 2015, Jun-06, Volume: 15

    Topics: Aged; Alanine; Antioxidants; Cornea; Dry Eye Syndromes; Enzyme Inhibitors; Female; Fluorescein; Fluorescent Dyes; Humans; Male; Ophthalmic Solutions; Quinolones; Retrospective Studies; Suspensions

2015
Evaluation of Tear Meniscus Dynamics Using Anterior Segment Swept-Source Optical Coherence Tomography After Topical Solution Instillation for Dry Eye.
    Cornea, 2016, Volume: 35, Issue:5

    Topics: Administration, Topical; Adult; Alanine; Anterior Eye Segment; Cross-Sectional Studies; Dry Eye Syndromes; Female; Humans; Hyaluronic Acid; Male; Ophthalmic Solutions; Polyphosphates; Prospective Studies; Quinolones; Tears; Tomography, Optical Coherence; Uracil Nucleotides

2016
Do Cyclosporine A, an IL-1 Receptor Antagonist, Uridine Triphosphate, Rebamipide, and/or Bimatoprost Regulate Human Meibomian Gland Epithelial Cells?
    Investigative ophthalmology & visual science, 2016, 08-01, Volume: 57, Issue:10

    Topics: Alanine; Antihypertensive Agents; Antioxidants; Antirheumatic Agents; Bimatoprost; Cell Count; Cell Proliferation; Cell Survival; Cells, Cultured; Cyclosporine; Dry Eye Syndromes; Epithelial Cells; Humans; Immunosuppressive Agents; Interleukin 1 Receptor Antagonist Protein; Meibomian Glands; Quinolones; Signal Transduction; Uridine Triphosphate

2016
A Clinic-based Survey of Clinical Characteristics and Practice Pattern of Dry Eye in Japan.
    Advances in therapy, 2017, Volume: 34, Issue:3

    Topics: Aged; Alanine; Cross-Sectional Studies; Diagnostic Techniques, Ophthalmological; Dry Eye Syndromes; Female; Humans; Hyaluronic Acid; Japan; Male; Middle Aged; Ophthalmic Solutions; Polyphosphates; Practice Patterns, Physicians'; Prevalence; Quinolones; Symptom Assessment; Treatment Outcome; Uracil Nucleotides

2017