carboprost and Puerperal-Disorders

Six cases of acute puerperal inversion of the uterus are reported. In four of these, tocolytic agents were used to facilitate replacement of the inverted uterus; and in five, Prostin-15M was given after replacement. The use of tocolytics may obviate the need for general anesthesia for uterine replacement in some patients with uterine inversion. Prostin-15M serves to minimize bleeding and to maintain uterine position after replacement.

Topics: Adult; Carboprost; Combined Modality Therapy; Female; Humans; Magnesium Sulfate; Oxytocin; Pregnancy; Puerperal Disorders; Terbutaline; Uterine Contraction; Uterine Diseases

Sequential administration of a beta 2-mimetic and a prostaglandin, the latter preferably injected into the uterus, is a simple and highly effective method for managing acute puerperal uterine inversion.

Topics: Carboprost; Dinoprostone; Drug Therapy, Combination; Female; Fenoterol; Humans; Pregnancy; Prostaglandins E; Prostaglandins E, Synthetic; Prostaglandins F, Synthetic; Puerperal Disorders; Ritodrine; Uterine Diseases

The present report describes an unusual case of recurrent puerperal uterine inversion causing major postpartum hemorrhage. Blood replacement, oxytocin, and ergot therapy along with manual reduction failed to prevent immediate recurrence, but treatment with 15(S)-15-methyl prostaglandin F2 alpha (Prostin 15M) and uterine packing were successful. It is recommended that 15(S)-15-methyl prostaglandin F2 alpha be available in all obstetric suites for the management of similar emergencies.

Topics: Adult; Carboprost; Female; Humans; Methods; Postpartum Hemorrhage; Pregnancy; Prostaglandins F, Synthetic; Puerperal Disorders; Recurrence; Uterine Diseases; Uterine Hemorrhage