Page last updated: 2024-10-26

carbonyl cyanide p-trifluoromethoxyphenylhydrazone and Innate Inflammatory Response

carbonyl cyanide p-trifluoromethoxyphenylhydrazone has been researched along with Innate Inflammatory Response in 3 studies

Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone: A proton ionophore that is commonly used as an uncoupling agent in biochemical studies.
carbonyl cyanide p-trifluoromethoxyphenylhydrazone : A hydrazone that is hydrazonomalononitrile in which one of the hydrazine hydrogens is substituted by a p-trifluoromethoxyphenyl group.

Research Excerpts

ExcerptRelevanceReference
"Our findings reveal a key role for mitochondrial bioenergetics in regulation of CXCL8-mediated inflammation by HGF through the adenosine/AMPK/SIRT1/PGC-1α axis."4.31Metabolic reprogramming through mitochondrial biogenesis drives adenosine anti-inflammatory effects: new mechanism controlling gingival fibroblast hyper-inflammatory state. ( Cutler, CW; Dawson, S; Huo, Y; Messer, R; Morandini, AC; Paladines, N; Ramos-Junior, ES; Ryan, W; Serrano-Lopez, R, 2023)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Paladines, N1
Dawson, S1
Ryan, W1
Serrano-Lopez, R1
Messer, R1
Huo, Y1
Cutler, CW1
Ramos-Junior, ES1
Morandini, AC1
Pan, X1
Song, Y1
He, M1
Yan, X1
Huang, C1
Li, J1
Dong, W1
Cheng, J1
Jia, J1
Ichimura, H1
Parthasarathi, K1
Quadri, S1
Issekutz, AC1
Bhattacharya, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Periodontal Status Assessment, Molecular Mechanisms Underlying Inflammatory Response, and Endothelial Dysfunction Evaluation in Patients With Polycystic Ovary Syndrome[NCT06184412]100 participants (Actual)Observational2020-02-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for carbonyl cyanide p-trifluoromethoxyphenylhydrazone and Innate Inflammatory Response

ArticleYear
Metabolic reprogramming through mitochondrial biogenesis drives adenosine anti-inflammatory effects: new mechanism controlling gingival fibroblast hyper-inflammatory state.
    Frontiers in immunology, 2023, Volume: 14

    Topics: Adenosine; AMP-Activated Protein Kinases; Anti-Inflammatory Agents; Carbonyl Cyanide p-Trifluorometh

2023
Mitochondrial Uncouplers Confer Protection by Activating AMP-Activated Protein Kinase to Inhibit Neuroinflammation Following Intracerebral Hemorrhage.
    Biological & pharmaceutical bulletin, 2020, Volume: 43, Issue:8

    Topics: AMP-Activated Protein Kinases; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, C

2020
Mechano-oxidative coupling by mitochondria induces proinflammatory responses in lung venular capillaries.
    The Journal of clinical investigation, 2003, Volume: 111, Issue:5

    Topics: Animals; Calcium Signaling; Capillaries; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Endothe

2003