carbonyl cyanide p-trifluoromethoxyphenylhydrazone has been researched along with Brain Injuries in 3 studies
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone: A proton ionophore that is commonly used as an uncoupling agent in biochemical studies.
carbonyl cyanide p-trifluoromethoxyphenylhydrazone : A hydrazone that is hydrazonomalononitrile in which one of the hydrazine hydrogens is substituted by a p-trifluoromethoxyphenyl group.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The current study was designed to determine the optimal dosage and therapeutic window of opportunity for the potent mitochondrial uncoupler FCCP following moderate TBI." | 1.35 | The optimal dosage and window of opportunity to maintain mitochondrial homeostasis following traumatic brain injury using the uncoupler FCCP. ( Pandya, JD; Pauly, JR; Sullivan, PG, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pandya, JD | 2 |
| Pauly, JR | 2 |
| Sullivan, PG | 2 |
| Krisanova, N | 1 |
| Sivko, R | 1 |
| Kasatkina, L | 1 |
| Borisova, T | 1 |
| Nukala, VN | 1 |
| Sebastian, AH | 1 |
| Day, KM | 1 |
| Korde, AS | 1 |
| Maragos, WF | 1 |
| Hall, ED | 1 |
3 other studies available for carbonyl cyanide p-trifluoromethoxyphenylhydrazone and Brain Injuries
| Article | Year |
|---|---|
The optimal dosage and window of opportunity to maintain mitochondrial homeostasis following traumatic brain injury using the uncoupler FCCP.
Topics: Animals; Brain Injuries; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Disease Models, Animal; | 2009 |
Neuroprotection by lowering cholesterol: a decrease in membrane cholesterol content reduces transporter-mediated glutamate release from brain nerve terminals.
Topics: Amino Acid Transport System X-AG; Animals; beta-Cyclodextrins; Brain; Brain Injuries; Carbonyl Cyani | 2012 |
Post-Injury Administration of Mitochondrial Uncouplers Increases Tissue Sparing and Improves Behavioral Outcome following Traumatic Brain Injury in Rodents.
Topics: 2,4-Dinitrophenol; Animals; Brain; Brain Injuries; Calcium Signaling; Carbonyl Cyanide p-Trifluorome | 2007 |