carbonyl cyanide m-chlorophenyl hydrazone has been researched along with Tuberculosis, Multidrug-Resistant in 4 studies
Carbonyl Cyanide m-Chlorophenyl Hydrazone: A proton ionophore. It is commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.
CCCP : A member of the class of monochlorobenzenes that is benzene substituted by 2-(1,3-dinitrilopropan-2-ylidene)hydrazinyl and chloro groups at positions 1 and 3, respectively. It is a mitochondrial depolarizing agent that induces reactive oxygen species mediated cell death.
Tuberculosis, Multidrug-Resistant: Tuberculosis resistant to chemotherapy with two or more ANTITUBERCULAR AGENTS, including at least ISONIAZID and RIFAMPICIN. The problem of resistance is particularly troublesome in tuberculous OPPORTUNISTIC INFECTIONS associated with HIV INFECTIONS. It requires the use of second line drugs which are more toxic than the first line regimens. TB with isolates that have developed further resistance to at least three of the six classes of second line drugs is defined as EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 4 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Sun, Z | 1 |
Xu, Y | 1 |
Sun, Y | 1 |
Liu, Y | 1 |
Zhang, X | 1 |
Huang, H | 1 |
Li, C | 1 |
Li, W | 1 |
Upadhyay, A | 1 |
Fontes, FL | 1 |
North, EJ | 1 |
Wang, Y | 1 |
Crans, DC | 1 |
Grzegorzewicz, AE | 1 |
Jones, V | 1 |
Franzblau, SG | 1 |
Lee, RE | 1 |
Crick, DC | 1 |
Jackson, M | 1 |
Gupta, AK | 1 |
Katoch, VM | 1 |
Chauhan, DS | 1 |
Sharma, R | 1 |
Singh, M | 1 |
Venkatesan, K | 1 |
Sharma, VD | 1 |
Ramos, DF | 1 |
Almeida da Silva, PE | 1 |
4 other studies available for carbonyl cyanide m-chlorophenyl hydrazone and Tuberculosis, Multidrug-Resistant
Article | Year |
---|---|
Ofloxacin resistance in Mycobacterium tuberculosis is associated with efflux pump activity independent of resistance pattern and genotype.
Topics: Antitubercular Agents; Bacterial Proteins; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Genotype; Micr | 2014 |
Novel insights into the mechanism of inhibition of MmpL3, a target of multiple pharmacophores in Mycobacterium tuberculosis.
Topics: Adamantane; Anti-Bacterial Agents; Antitubercular Agents; Bacterial Proteins; Carbonyl Cyanide m-Chl | 2014 |
Microarray analysis of efflux pump genes in multidrug-resistant Mycobacterium tuberculosis during stress induced by common anti-tuberculous drugs.
Topics: Antitubercular Agents; Bacterial Proteins; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Ethambutol; Ge | 2010 |
Antimycobacterial activity of usnic acid against resistant and susceptible strains of Mycobacterium tuberculosis and non-tuberculous mycobacteria.
Topics: Anti-Bacterial Agents; Benzofurans; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl Hydraz | 2010 |