carbonyl cyanide m-chlorophenyl hydrazone has been researched along with Pulmonary Hypertension in 1 studies
Carbonyl Cyanide m-Chlorophenyl Hydrazone: A proton ionophore. It is commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.
CCCP : A member of the class of monochlorobenzenes that is benzene substituted by 2-(1,3-dinitrilopropan-2-ylidene)hydrazinyl and chloro groups at positions 1 and 3, respectively. It is a mitochondrial depolarizing agent that induces reactive oxygen species mediated cell death.
Excerpt | Relevance | Reference |
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" MMP was measured by JC-1 in isolated pulmonary arterial smooth muscle cells (PASMCs) of patients with PH and animals with PH induced by exposure to monocrotaline (MCT) or chronic hypoxia." | 3.79 | Mitochondrial hyperpolarization in pulmonary vascular remodeling. Mitochondrial uncoupling protein deficiency as disease model. ( Bakr, A; Esfandiary, A; Fuchs, B; Ghofrani, HA; Grimminger, F; Haag, D; Hecker, M; Hoeres, T; Kojonazarov, B; Pak, O; Schermuly, RT; Seeger, W; Sommer, N; Sydykov, A; Veit, F; Waisbrod, S; Weisel, FC; Weissmann, N, 2013) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Pak, O | 1 |
Sommer, N | 1 |
Hoeres, T | 1 |
Bakr, A | 1 |
Waisbrod, S | 1 |
Sydykov, A | 1 |
Haag, D | 1 |
Esfandiary, A | 1 |
Kojonazarov, B | 1 |
Veit, F | 1 |
Fuchs, B | 1 |
Weisel, FC | 1 |
Hecker, M | 1 |
Schermuly, RT | 1 |
Grimminger, F | 1 |
Ghofrani, HA | 1 |
Seeger, W | 1 |
Weissmann, N | 1 |
1 other study available for carbonyl cyanide m-chlorophenyl hydrazone and Pulmonary Hypertension
Article | Year |
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Mitochondrial hyperpolarization in pulmonary vascular remodeling. Mitochondrial uncoupling protein deficiency as disease model.
Topics: Animals; Benzimidazoles; Carbocyanines; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Disease Models, A | 2013 |