carbonyl cyanide m-chlorophenyl hydrazone has been researched along with Malignant Melanoma in 2 studies
Carbonyl Cyanide m-Chlorophenyl Hydrazone: A proton ionophore. It is commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.
CCCP : A member of the class of monochlorobenzenes that is benzene substituted by 2-(1,3-dinitrilopropan-2-ylidene)hydrazinyl and chloro groups at positions 1 and 3, respectively. It is a mitochondrial depolarizing agent that induces reactive oxygen species mediated cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Based on the functional mechanism of iron shown above, we further demonstrate that iron supplementation at a dosage used in iron-deficient patients is sufficient to maximize the anti-tumor effect of clinical ROS-inducing drugs to inhibit xenograft tumor growth and metastasis of melanoma cells through GSDME-dependent pyroptosis." | 1.48 | Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis. ( Ai, YL; Chen, HZ; Cheng, K; Han, J; Liu, XS; Sun, RY; Wu, Q; Zhang, JY; Zhou, B; Zhou, D, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, B | 1 |
| Zhang, JY | 1 |
| Liu, XS | 1 |
| Chen, HZ | 1 |
| Ai, YL | 1 |
| Cheng, K | 1 |
| Sun, RY | 1 |
| Zhou, D | 1 |
| Han, J | 1 |
| Wu, Q | 1 |
| Knowles, AF | 1 |
| Kaplan, NO | 1 |
2 other studies available for carbonyl cyanide m-chlorophenyl hydrazone and Malignant Melanoma
| Article | Year |
|---|---|
Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; bcl-2-Associated X P | 2018 |
Oxidative phosphorylation and ATPase activities of human tumor mitochondria.
Topics: Adenosine Triphosphatases; Animals; Astrocytoma; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carcinom | 1980 |