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carbonyl cyanide m-chlorophenyl hydrazone and Hypertension, Pulmonary

carbonyl cyanide m-chlorophenyl hydrazone has been researched along with Hypertension, Pulmonary in 1 studies

Carbonyl Cyanide m-Chlorophenyl Hydrazone: A proton ionophore. It is commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.
CCCP : A member of the class of monochlorobenzenes that is benzene substituted by 2-(1,3-dinitrilopropan-2-ylidene)hydrazinyl and chloro groups at positions 1 and 3, respectively. It is a mitochondrial depolarizing agent that induces reactive oxygen species mediated cell death.

Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.

Research Excerpts

ExcerptRelevanceReference
" MMP was measured by JC-1 in isolated pulmonary arterial smooth muscle cells (PASMCs) of patients with PH and animals with PH induced by exposure to monocrotaline (MCT) or chronic hypoxia."3.79Mitochondrial hyperpolarization in pulmonary vascular remodeling. Mitochondrial uncoupling protein deficiency as disease model. ( Bakr, A; Esfandiary, A; Fuchs, B; Ghofrani, HA; Grimminger, F; Haag, D; Hecker, M; Hoeres, T; Kojonazarov, B; Pak, O; Schermuly, RT; Seeger, W; Sommer, N; Sydykov, A; Veit, F; Waisbrod, S; Weisel, FC; Weissmann, N, 2013)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pak, O1
Sommer, N1
Hoeres, T1
Bakr, A1
Waisbrod, S1
Sydykov, A1
Haag, D1
Esfandiary, A1
Kojonazarov, B1
Veit, F1
Fuchs, B1
Weisel, FC1
Hecker, M1
Schermuly, RT1
Grimminger, F1
Ghofrani, HA1
Seeger, W1
Weissmann, N1

Other Studies

1 other study available for carbonyl cyanide m-chlorophenyl hydrazone and Hypertension, Pulmonary

ArticleYear
Mitochondrial hyperpolarization in pulmonary vascular remodeling. Mitochondrial uncoupling protein deficiency as disease model.
    American journal of respiratory cell and molecular biology, 2013, Volume: 49, Issue:3

    Topics: Animals; Benzimidazoles; Carbocyanines; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Disease Models, A

2013