carbonyl cyanide m-chlorophenyl hydrazone has been researched along with Glial Cell Tumors in 6 studies
Carbonyl Cyanide m-Chlorophenyl Hydrazone: A proton ionophore. It is commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.
CCCP : A member of the class of monochlorobenzenes that is benzene substituted by 2-(1,3-dinitrilopropan-2-ylidene)hydrazinyl and chloro groups at positions 1 and 3, respectively. It is a mitochondrial depolarizing agent that induces reactive oxygen species mediated cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "High grade gliomas are one of the most difficult cancers to treat and despite surgery, radiotherapy and temozolomide-based chemotherapy, the prognosis of glioma patients is poor." | 7.75 | Drugs targeting the mitochondrial pore act as cytotoxic and cytostatic agents in temozolomide-resistant glioma cells. ( Amoroso, R; Bartoli, B; Benvenuti, L; Gagliardi, R; Gremigni, V; Lena, A; Rechichi, M; Rossi, L; Salvetti, A; Scarcelli, V; Vecchio, D, 2009) |
| " This study examined the effect of riluzole on [Ca2+]i in IMR32 neuroblastoma cells using fura-2 as a Ca2+ probe." | 7.71 | Effect of the neuroprotective agent riluzole on intracellular Ca2+ levels in IMR32 neuroblastoma cells. ( Chang, CH; Chen, WC; Chow, CK; Jan, CR; Law, YP; Lee, KC; Lu, T; Su, W; Tang, KY; Wang, JL, 2001) |
| " In this report, we present the synthesis and evaluation of (64)Cu-labeled Lissamine rhodamine B (LRB), (64)Cu(DOTA-LRB) (DOTA-LRB = 2-(6-(diethylamino)-3-(diethyliminio)-3H-xanthen-9-yl)-5-(N-(2-(2-(4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclo-dodecan-1-yl)acetamido)ethyl)sulfamoyl)benzenesulfonate) as a new radiotracer for imaging tumors in athymic nude mice bearing U87MG human glioma xenografts by positron emission tomography (PET)." | 3.77 | 64Cu-labeled lissamine rhodamine B: a promising PET radiotracer targeting tumor mitochondria. ( Chen, X; Jacobson, O; Kim, YS; Liu, S; Yan, X; Zhou, Y, 2011) |
| "High grade gliomas are one of the most difficult cancers to treat and despite surgery, radiotherapy and temozolomide-based chemotherapy, the prognosis of glioma patients is poor." | 3.75 | Drugs targeting the mitochondrial pore act as cytotoxic and cytostatic agents in temozolomide-resistant glioma cells. ( Amoroso, R; Bartoli, B; Benvenuti, L; Gagliardi, R; Gremigni, V; Lena, A; Rechichi, M; Rossi, L; Salvetti, A; Scarcelli, V; Vecchio, D, 2009) |
| " This study examined the effect of riluzole on [Ca2+]i in IMR32 neuroblastoma cells using fura-2 as a Ca2+ probe." | 3.71 | Effect of the neuroprotective agent riluzole on intracellular Ca2+ levels in IMR32 neuroblastoma cells. ( Chang, CH; Chen, WC; Chow, CK; Jan, CR; Law, YP; Lee, KC; Lu, T; Su, W; Tang, KY; Wang, JL, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lena, A | 1 |
| Rechichi, M | 1 |
| Salvetti, A | 1 |
| Bartoli, B | 1 |
| Vecchio, D | 1 |
| Scarcelli, V | 1 |
| Amoroso, R | 1 |
| Benvenuti, L | 1 |
| Gagliardi, R | 1 |
| Gremigni, V | 1 |
| Rossi, L | 1 |
| Zhou, Y | 1 |
| Kim, YS | 1 |
| Yan, X | 1 |
| Jacobson, O | 1 |
| Chen, X | 1 |
| Liu, S | 1 |
| Gérard, V | 1 |
| Rouzaire-Dubois, B | 1 |
| Dubois, JM | 1 |
| Waśniewska, M | 1 |
| Duszyński, J | 1 |
| Wang, JL | 1 |
| Lee, KC | 1 |
| Tang, KY | 1 |
| Lu, T | 1 |
| Chang, CH | 1 |
| Chow, CK | 1 |
| Chen, WC | 1 |
| Su, W | 1 |
| Law, YP | 1 |
| Jan, CR | 1 |
| Chueh, SH | 1 |
| Liu, JA | 1 |
| Kao, LS | 1 |
6 other studies available for carbonyl cyanide m-chlorophenyl hydrazone and Glial Cell Tumors
| Article | Year |
|---|---|
Drugs targeting the mitochondrial pore act as cytotoxic and cytostatic agents in temozolomide-resistant glioma cells.
Topics: Acridine Orange; Betulinic Acid; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Death; Cell Line, T | 2009 |
64Cu-labeled lissamine rhodamine B: a promising PET radiotracer targeting tumor mitochondria.
Topics: Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line, Tumor; Chromatography, High Pressure | 2011 |
Contribution of a H+ pump in determining the resting potential of neuroblastoma cells.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell M | 1994 |
The role of mitochondrial dysfunction in regulation of store-operated calcium channels in glioma C6 and human fibroblast cells.
Topics: Animals; Calcium; Calcium Channels; Calcium-Transporting ATPases; Carbonyl Cyanide m-Chlorophenyl Hy | 2000 |
Effect of the neuroprotective agent riluzole on intracellular Ca2+ levels in IMR32 neuroblastoma cells.
Topics: Animals; Brefeldin A; Calcium; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl Hydrazone; | 2001 |
Intracellular calcium pools in neuroblastoma x glioma hybrid NG108-15 cells.
Topics: Adenosine Triphosphate; Animals; Biological Transport, Active; Calcimycin; Calcium; Calcium-Transpor | 1990 |