carbonyl cyanide m-chlorophenyl hydrazone has been researched along with Fibrosarcoma in 1 studies
Carbonyl Cyanide m-Chlorophenyl Hydrazone: A proton ionophore. It is commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.
CCCP : A member of the class of monochlorobenzenes that is benzene substituted by 2-(1,3-dinitrilopropan-2-ylidene)hydrazinyl and chloro groups at positions 1 and 3, respectively. It is a mitochondrial depolarizing agent that induces reactive oxygen species mediated cell death.
Fibrosarcoma: A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Both nigericin and CCCP were observed to penetrate tissue based on their ability to kill tumour cells in spheroids." | 1.28 | Effects of agents which inhibit the regulation of intracellular pH on murine solid tumours. ( Newell, K; Stratford, I; Tannock, I; Wood, P, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Newell, K | 1 |
| Wood, P | 1 |
| Stratford, I | 1 |
| Tannock, I | 1 |
1 other study available for carbonyl cyanide m-chlorophenyl hydrazone and Fibrosarcoma
| Article | Year |
|---|---|
Effects of agents which inhibit the regulation of intracellular pH on murine solid tumours.
Topics: Amiloride; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Division; Cell Survival; Fibrosa | 1992 |