carbonyl cyanide m-chlorophenyl hydrazone has been researched along with Disease Models, Animal in 15 studies
Carbonyl Cyanide m-Chlorophenyl Hydrazone: A proton ionophore. It is commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.
CCCP : A member of the class of monochlorobenzenes that is benzene substituted by 2-(1,3-dinitrilopropan-2-ylidene)hydrazinyl and chloro groups at positions 1 and 3, respectively. It is a mitochondrial depolarizing agent that induces reactive oxygen species mediated cell death.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " MMP was measured by JC-1 in isolated pulmonary arterial smooth muscle cells (PASMCs) of patients with PH and animals with PH induced by exposure to monocrotaline (MCT) or chronic hypoxia." | 3.79 | Mitochondrial hyperpolarization in pulmonary vascular remodeling. Mitochondrial uncoupling protein deficiency as disease model. ( Bakr, A; Esfandiary, A; Fuchs, B; Ghofrani, HA; Grimminger, F; Haag, D; Hecker, M; Hoeres, T; Kojonazarov, B; Pak, O; Schermuly, RT; Seeger, W; Sommer, N; Sydykov, A; Veit, F; Waisbrod, S; Weisel, FC; Weissmann, N, 2013) |
| "Brain cells in Alzheimer's disease (AD) exhibit a membrane defect characterized by accelerated phospholipid turnover." | 1.31 | Acceleration of phosphatidylcholine synthesis and breakdown by inhibitors of mitochondrial function in neuronal cells: a model of the membrane defect of Alzheimer's disease. ( Blusztajn, JK; Farber, SA; Slack, BE, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 10 (66.67) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Upadhyay, A | 1 |
| Chandrakar, P | 1 |
| Gupta, S | 1 |
| Parmar, N | 1 |
| Singh, SK | 1 |
| Rashid, M | 1 |
| Kushwaha, P | 1 |
| Wahajuddin, M | 1 |
| Sashidhara, KV | 1 |
| Kar, S | 1 |
| Wu, Z | 1 |
| Wang, Y | 2 |
| Yan, G | 1 |
| Wu, C | 1 |
| Qutob, HMH | 1 |
| Saad, RA | 1 |
| Bali, H | 1 |
| Osailan, A | 1 |
| Jaber, J | 1 |
| Alzahrani, E | 1 |
| Alyami, J | 1 |
| Elsayed, H | 1 |
| Alserihi, R | 1 |
| Shaikhomar, OA | 1 |
| Divya, KM | 1 |
| Savitha, DP | 1 |
| Krishna, GA | 1 |
| Dhanya, TM | 1 |
| Mohanan, PV | 1 |
| Shah, SF | 1 |
| Jafry, AT | 1 |
| Hussain, G | 1 |
| Kazim, AH | 1 |
| Ali, M | 1 |
| Rivani, E | 1 |
| Endraswari, PD | 1 |
| Widodo, ADW | 1 |
| Khalil, MR | 1 |
| Guldberg, R | 1 |
| Nørgård, BM | 1 |
| Uldbjerg, N | 1 |
| Wehberg, S | 1 |
| Fowobaje, KR | 1 |
| Mashood, LO | 1 |
| Ekholuenetale, M | 1 |
| Ibidoja, OJ | 1 |
| Romagnoli, A | 1 |
| D'Agostino, M | 1 |
| Pavoni, E | 1 |
| Ardiccioni, C | 1 |
| Motta, S | 1 |
| Crippa, P | 1 |
| Biagetti, G | 1 |
| Notarstefano, V | 1 |
| Rexha, J | 1 |
| Perta, N | 1 |
| Barocci, S | 1 |
| Costabile, BK | 1 |
| Colasurdo, G | 1 |
| Caucci, S | 1 |
| Mencarelli, D | 1 |
| Turchetti, C | 1 |
| Farina, M | 1 |
| Pierantoni, L | 1 |
| La Teana, A | 1 |
| Al Hadi, R | 1 |
| Cicconardi, F | 1 |
| Chinappi, M | 1 |
| Trucchi, E | 1 |
| Mancia, F | 1 |
| Menzo, S | 1 |
| Morozzo Della Rocca, B | 1 |
| D'Annessa, I | 1 |
| Di Marino, D | 1 |
| Choya, A | 1 |
| de Rivas, B | 1 |
| Gutiérrez-Ortiz, JI | 1 |
| López-Fonseca, R | 1 |
| Xu, S | 1 |
| Cheng, B | 1 |
| Huang, Z | 1 |
| Liu, T | 1 |
| Li, Y | 1 |
| Jiang, L | 1 |
| Guo, W | 1 |
| Xiong, J | 1 |
| Amirazodi, M | 1 |
| Daryanoosh, F | 1 |
| Mehrabi, A | 1 |
| Gaeini, A | 1 |
| Koushkie Jahromi, M | 1 |
| Salesi, M | 1 |
| Zarifkar, AH | 1 |
| Studeny, P | 1 |
| Netukova, M | 1 |
| Nemcokova, M | 1 |
| Klimesova, YM | 1 |
| Krizova, D | 1 |
| Kang, H | 1 |
| Tao, Y | 1 |
| Zhang, Q | 1 |
| Sha, D | 1 |
| Chen, Y | 1 |
| Yao, J | 1 |
| Gao, Y | 1 |
| Liu, J | 1 |
| Ji, L | 1 |
| Shi, P | 1 |
| Shi, C | 1 |
| Wu, YL | 1 |
| Wright, AI | 1 |
| M El-Metwaly, N | 1 |
| A Katouah, H | 1 |
| El-Desouky, MG | 1 |
| El-Bindary, AA | 1 |
| El-Bindary, MA | 1 |
| Kostakis, ID | 1 |
| Raptis, DA | 1 |
| Davidson, BR | 1 |
| Iype, S | 1 |
| Nasralla, D | 1 |
| Imber, C | 1 |
| Sharma, D | 1 |
| Pissanou, T | 1 |
| Pollok, JM | 1 |
| Hughes, AM | 1 |
| Sanderson, E | 1 |
| Morris, T | 1 |
| Ayorech, Z | 1 |
| Tesli, M | 1 |
| Ask, H | 1 |
| Reichborn-Kjennerud, T | 1 |
| Andreassen, OA | 1 |
| Magnus, P | 1 |
| Helgeland, Ø | 1 |
| Johansson, S | 1 |
| Njølstad, P | 1 |
| Davey Smith, G | 1 |
| Havdahl, A | 1 |
| Howe, LD | 1 |
| Davies, NM | 1 |
| Amrillah, T | 1 |
| Prasetio, A | 1 |
| Supandi, AR | 1 |
| Sidiq, DH | 1 |
| Putra, FS | 1 |
| Nugroho, MA | 1 |
| Salsabilla, Z | 1 |
| Azmi, R | 1 |
| Grammatikopoulos, P | 1 |
| Bouloumis, T | 1 |
| Steinhauer, S | 1 |
| Mironov, VS | 2 |
| Bazhenova, TA | 2 |
| Manakin, YV | 2 |
| Yagubskii, EB | 2 |
| Yakushev, IA | 1 |
| Gilmutdinov, IF | 1 |
| Simonov, SV | 1 |
| Lan, K | 1 |
| Yang, H | 1 |
| Zheng, J | 1 |
| Hu, H | 1 |
| Zhu, T | 1 |
| Zou, X | 1 |
| Hu, B | 1 |
| Liu, H | 1 |
| Olokede, O | 1 |
| Wu, H | 1 |
| Holtzapple, M | 1 |
| Gungor, O | 1 |
| Kose, M | 1 |
| Ghaemi, R | 1 |
| Acker, M | 1 |
| Stosic, A | 1 |
| Jacobs, R | 1 |
| Selvaganapathy, PR | 1 |
| Ludwig, N | 1 |
| Yerneni, SS | 1 |
| Azambuja, JH | 1 |
| Pietrowska, M | 1 |
| Widłak, P | 1 |
| Hinck, CS | 1 |
| Głuszko, A | 1 |
| Szczepański, MJ | 1 |
| Kärmer, T | 1 |
| Kallinger, I | 1 |
| Schulz, D | 1 |
| Bauer, RJ | 1 |
| Spanier, G | 1 |
| Spoerl, S | 1 |
| Meier, JK | 1 |
| Ettl, T | 1 |
| Razzo, BM | 1 |
| Reichert, TE | 1 |
| Hinck, AP | 1 |
| Whiteside, TL | 1 |
| Wei, ZL | 1 |
| Juan, W | 1 |
| Tong, D | 1 |
| Juan, LX | 1 |
| Sa, LY | 1 |
| Jie, HFM | 1 |
| Xiao, G | 1 |
| Xiang, LG | 1 |
| Jie, HM | 1 |
| Xu, C | 1 |
| Yu, DN | 1 |
| Yao, ZX | 1 |
| Bigdeli, F | 1 |
| Gao, XM | 1 |
| Cheng, X | 1 |
| Li, JZ | 1 |
| Zhang, JW | 1 |
| Wang, W | 3 |
| Guan, ZJ | 1 |
| Bu, Y | 1 |
| Liu, KG | 1 |
| Morsali, A | 1 |
| Das, R | 1 |
| Paul, R | 1 |
| Parui, A | 1 |
| Shrotri, A | 1 |
| Atzori, C | 1 |
| Lomachenko, KA | 1 |
| Singh, AK | 1 |
| Mondal, J | 1 |
| Peter, SC | 1 |
| Florimbio, AR | 1 |
| Coughlin, LN | 1 |
| Bauermeister, JA | 1 |
| Young, SD | 1 |
| Zimmerman, MA | 1 |
| Walton, MA | 1 |
| Bonar, EE | 1 |
| Demir, D | 1 |
| Balci, AB | 1 |
| Kahraman, N | 1 |
| Sunbul, SA | 1 |
| Gucu, A | 1 |
| Seker, IB | 1 |
| Badem, S | 1 |
| Yuksel, A | 1 |
| Ozyazicioglu, AF | 1 |
| Goncu, MT | 1 |
| Zhang, H | 1 |
| Zhou, H | 1 |
| Deng, Z | 1 |
| Luo, L | 1 |
| Ong, SP | 1 |
| Wang, C | 1 |
| Xin, H | 1 |
| Whittingham, MS | 1 |
| Zhou, G | 1 |
| Maemura, R | 1 |
| Wakamatsu, M | 1 |
| Matsumoto, K | 1 |
| Sakaguchi, H | 1 |
| Yoshida, N | 1 |
| Hama, A | 1 |
| Yoshida, T | 1 |
| Miwata, S | 1 |
| Kitazawa, H | 1 |
| Narita, K | 1 |
| Kataoka, S | 1 |
| Ichikawa, D | 1 |
| Hamada, M | 1 |
| Taniguchi, R | 1 |
| Suzuki, K | 1 |
| Kawashima, N | 1 |
| Nishikawa, E | 1 |
| Narita, A | 1 |
| Okuno, Y | 1 |
| Nishio, N | 1 |
| Kato, K | 1 |
| Kojima, S | 1 |
| Morita, K | 1 |
| Muramatsu, H | 1 |
| Takahashi, Y | 1 |
| Yirgu, A | 1 |
| Mekonnen, Y | 1 |
| Eyado, A | 1 |
| Staropoli, A | 1 |
| Vinale, F | 1 |
| Zac, J | 1 |
| Zac, S | 1 |
| Pérez-Padilla, R | 1 |
| Remigio-Luna, A | 1 |
| Guzmán-Boulloud, N | 1 |
| Gochicoa-Rangel, L | 1 |
| Guzmán-Valderrábano, C | 1 |
| Thirión-Romero, I | 1 |
| Statsenko, ME | 1 |
| Turkina, SV | 1 |
| Barantsevich, ER | 1 |
| Karakulova, YV | 1 |
| Baranova, NS | 1 |
| Morzhukhina, MV | 1 |
| Wang, Q | 1 |
| Gu, Y | 1 |
| Chen, C | 1 |
| Qiao, L | 1 |
| Pan, F | 1 |
| Song, C | 1 |
| Canetto, SS | 1 |
| Entilli, L | 1 |
| Cerbo, I | 1 |
| Cipolletta, S | 1 |
| Wu, Y | 2 |
| Zhu, P | 1 |
| Jiang, Y | 1 |
| Zhang, X | 1 |
| Wang, Z | 1 |
| Xie, B | 1 |
| Song, T | 1 |
| Zhang, F | 1 |
| Luo, A | 1 |
| Li, S | 2 |
| Xiong, X | 1 |
| Han, J | 1 |
| Peng, X | 1 |
| Li, M | 1 |
| Huang, L | 1 |
| Chen, Q | 1 |
| Fang, W | 1 |
| Hou, Y | 1 |
| Zhu, Y | 1 |
| Ye, J | 1 |
| Liu, L | 1 |
| Islam, MR | 1 |
| Sanderson, P | 1 |
| Johansen, MP | 1 |
| Payne, TE | 1 |
| Naidu, R | 1 |
| Cao, J | 1 |
| Yang, J | 1 |
| Niu, X | 1 |
| Liu, X | 1 |
| Zhai, Y | 1 |
| Qiang, C | 1 |
| Niu, Y | 1 |
| Li, Z | 1 |
| Dong, N | 1 |
| Wen, B | 1 |
| Ouyang, Z | 1 |
| Zhang, Y | 2 |
| Li, J | 2 |
| Zhao, M | 1 |
| Zhao, J | 1 |
| Morici, P | 1 |
| Rizzato, C | 1 |
| Ghelardi, E | 1 |
| Rossolini, GM | 1 |
| Lupetti, A | 1 |
| Gözüküçük, R | 1 |
| Cakiroglu, B | 1 |
| He, X | 1 |
| Li, R | 1 |
| Zhao, D | 1 |
| Zhang, L | 1 |
| Ji, X | 1 |
| Fan, X | 1 |
| Chen, J | 2 |
| Luo, Y | 1 |
| Zheng, D | 1 |
| Xie, L | 1 |
| Sun, S | 1 |
| Cai, Z | 1 |
| Liu, Q | 1 |
| Ma, K | 1 |
| Sun, X | 1 |
| Drinkwater, JJ | 1 |
| Davis, TME | 1 |
| Turner, AW | 1 |
| Davis, WA | 1 |
| Suzuki, Y | 1 |
| Mizuta, Y | 1 |
| Mikagi, A | 1 |
| Misawa-Suzuki, T | 1 |
| Tsuchido, Y | 1 |
| Sugaya, T | 1 |
| Hashimoto, T | 1 |
| Ema, K | 1 |
| Hayashita, T | 1 |
| Minanimo-Muta, E | 1 |
| Kato, T | 2 |
| Shioi, T | 2 |
| Tanada, Y | 2 |
| Kimura, T | 2 |
| Wang, ZT | 1 |
| Lu, MH | 1 |
| Ji, WL | 1 |
| Lei, L | 1 |
| Fang, LP | 1 |
| Wang, LW | 1 |
| Yu, F | 1 |
| Wang, J | 1 |
| Li, ZY | 1 |
| Wang, JR | 1 |
| Wang, TH | 1 |
| Dou, F | 1 |
| Wang, QW | 1 |
| Wang, XL | 1 |
| Ma, QH | 1 |
| Xu, RX | 1 |
| Wang, S | 1 |
| Kwon, SH | 1 |
| Su, Y | 1 |
| Dong, Z | 1 |
| Pak, O | 1 |
| Sommer, N | 1 |
| Hoeres, T | 1 |
| Bakr, A | 1 |
| Waisbrod, S | 1 |
| Sydykov, A | 1 |
| Haag, D | 1 |
| Esfandiary, A | 1 |
| Kojonazarov, B | 1 |
| Veit, F | 1 |
| Fuchs, B | 1 |
| Weisel, FC | 1 |
| Hecker, M | 1 |
| Schermuly, RT | 1 |
| Grimminger, F | 1 |
| Ghofrani, HA | 1 |
| Seeger, W | 1 |
| Weissmann, N | 1 |
| Poliquin, PO | 1 |
| Cloutier, M | 1 |
| Trudeau, LÉ | 1 |
| Jolicoeur, M | 1 |
| Kawamoto, A | 1 |
| Okuda, J | 1 |
| Kawashima, T | 1 |
| Tamaki, Y | 1 |
| Niizuma, S | 1 |
| Takemura, G | 1 |
| Narazaki, M | 1 |
| Matsuda, T | 1 |
| Mauro-Lizcano, M | 1 |
| Esteban-Martínez, L | 1 |
| Seco, E | 1 |
| Serrano-Puebla, A | 1 |
| Garcia-Ledo, L | 1 |
| Figueiredo-Pereira, C | 1 |
| Vieira, HL | 1 |
| Boya, P | 1 |
| Allison, KR | 1 |
| Brynildsen, MP | 1 |
| Collins, JJ | 1 |
| Liu, S | 1 |
| Sawada, T | 1 |
| Lee, S | 1 |
| Yu, W | 1 |
| Silverio, G | 1 |
| Alapatt, P | 1 |
| Millan, I | 1 |
| Shen, A | 1 |
| Saxton, W | 1 |
| Kanao, T | 1 |
| Takahashi, R | 1 |
| Hattori, N | 1 |
| Imai, Y | 1 |
| Lu, B | 1 |
| Petrovic, MM | 1 |
| Scepanovic, L | 1 |
| Rosic, G | 1 |
| Mitrovic, DM | 1 |
| Farber, SA | 1 |
| Slack, BE | 1 |
| Blusztajn, JK | 1 |
| Dahle, J | 1 |
| Angell-Petersen, E | 1 |
| Steen, HB | 1 |
| Moan, J | 1 |
1 review available for carbonyl cyanide m-chlorophenyl hydrazone and Disease Models, Animal
| Article | Year |
|---|---|
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter | 2022 |
1 trial available for carbonyl cyanide m-chlorophenyl hydrazone and Disease Models, Animal
| Article | Year |
|---|---|
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter | 2022 |
14 other studies available for carbonyl cyanide m-chlorophenyl hydrazone and Disease Models, Animal
| Article | Year |
|---|---|
Synthesis, Biological Evaluation, Structure-Activity Relationship, and Mechanism of Action Studies of Quinoline-Metronidazole Derivatives Against Experimental Visceral Leishmaniasis.
Topics: Animals; Antiprotozoal Agents; Chemistry Techniques, Synthetic; Chlorocebus aethiops; Disease Models | 2019 |
Eugenol protects chondrocytes and articular cartilage by downregulating the JAK3/STAT4 signaling pathway.
Topics: Aged; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cartilage, Articular; Chondrocytes; Diseas | 2023 |
Cardiac effects of acute administration of a protonophore in a rat model.
Topics: Animals; Blood Pressure; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cardiotoxins; Disease Models, An | 2018 |
Disrupted-in-schizophrenia-1 protects synaptic plasticity in a transgenic mouse model of Alzheimer's disease as a mitophagy receptor.
Topics: Alzheimer Disease; Amino Acid Motifs; Amino Acid Sequence; Amyloid beta-Protein Precursor; Animals; | 2019 |
Stress granules are formed in renal proximal tubular cells during metabolic stress and ischemic injury for cell survival.
Topics: Acute Kidney Injury; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Survival; Cells, Cultu | 2019 |
Mitochondrial hyperpolarization in pulmonary vascular remodeling. Mitochondrial uncoupling protein deficiency as disease model.
Topics: Animals; Benzimidazoles; Carbocyanines; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Disease Models, A | 2013 |
Metabolomics and in-silico analysis reveal critical energy deregulations in animal models of Parkinson's disease.
Topics: Animals; Brain; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Computer Simulation; Disease Models, Anim | 2013 |
Measurement of technetium-99m sestamibi signals in rats administered a mitochondrial uncoupler and in a rat model of heart failure.
Topics: Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Disease Models, Animal; Heart Failure; Male; Mem | 2015 |
New method to assess mitophagy flux by flow cytometry.
Topics: Amino Acids; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Disease Models, Animal; Down-Regula | 2015 |
Metabolite-enabled eradication of bacterial persisters by aminoglycosides.
Topics: Aerobiosis; Aminoglycosides; Anaerobiosis; Animals; Anti-Bacterial Agents; Biofilms; Carbonyl Cyanid | 2011 |
Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria.
Topics: Animals; Autophagy; Axonal Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Disease Models, Ani | 2012 |
Properties of thiamine transport in isolated perfused hearts of chronically alcoholic guinea pigs.
Topics: Alcoholism; Animals; Biological Transport, Active; Carbon Radioisotopes; Carbonyl Cyanide m-Chloroph | 2008 |
Acceleration of phosphatidylcholine synthesis and breakdown by inhibitors of mitochondrial function in neuronal cells: a model of the membrane defect of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Choline; Cytidine Diphosphate | 2000 |
Bystander effects in cell death induced by photodynamic treatment UVA radiation and inhibitors of ATP synthesis.
Topics: Adenosine Triphosphate; Algorithms; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Communi | 2001 |