carbonyl cyanide m-chlorophenyl hydrazone has been researched along with Cystic Fibrosis in 2 studies
Carbonyl Cyanide m-Chlorophenyl Hydrazone: A proton ionophore. It is commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.
CCCP : A member of the class of monochlorobenzenes that is benzene substituted by 2-(1,3-dinitrilopropan-2-ylidene)hydrazinyl and chloro groups at positions 1 and 3, respectively. It is a mitochondrial depolarizing agent that induces reactive oxygen species mediated cell death.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " ATP dose-response experiments, taken together with the effect of cAMP with and without ATP, suggest that phosphorylation is necessary, but not sufficient, for activation." | 1.29 | Regulation of CFTR Cl- conductance in secretion by cellular energy levels. ( Bell, CL; Quinton, PM, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bell, CL | 1 |
| Quinton, PM | 1 |
| Van Dyke, RW | 1 |
| Root, KV | 1 |
| Schreiber, JH | 1 |
| Wilson, JM | 1 |
2 other studies available for carbonyl cyanide m-chlorophenyl hydrazone and Cystic Fibrosis
| Article | Year |
|---|---|
Regulation of CFTR Cl- conductance in secretion by cellular energy levels.
Topics: Adenosine; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Carbonyl Cyanide m-Chlorophenyl Hydraz | 1993 |
Role of CFTR in lysosome acidification.
Topics: Adenocarcinoma; Adenosine Triphosphate; Bucladesine; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell | 1992 |