carbonyl cyanide m-chlorophenyl hydrazone has been researched along with Cancer of Prostate in 8 studies
Carbonyl Cyanide m-Chlorophenyl Hydrazone: A proton ionophore. It is commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.
CCCP : A member of the class of monochlorobenzenes that is benzene substituted by 2-(1,3-dinitrilopropan-2-ylidene)hydrazinyl and chloro groups at positions 1 and 3, respectively. It is a mitochondrial depolarizing agent that induces reactive oxygen species mediated cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prostate cancer is a major cause of male death worldwide and the identification of new and improved treatments is constantly required." | 1.43 | Rational design and synthesis of novel anti-prostate cancer agents bearing a 3,5-bis-trifluoromethylphenyl moiety. ( Bassetto, M; Brancale, A; Ferla, S; Kandil, S; McGuigan, C; Pertusati, F; Westwell, AD, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bassetto, M | 2 |
| Ferla, S | 2 |
| Pertusati, F | 2 |
| Kandil, S | 2 |
| Westwell, AD | 2 |
| Brancale, A | 2 |
| McGuigan, C | 2 |
| Mandalapu, D | 1 |
| Saini, KS | 1 |
| Gupta, S | 1 |
| Sharma, V | 1 |
| Yaseen Malik, M | 1 |
| Chaturvedi, S | 1 |
| Bala, V | 1 |
| Thakur, S | 1 |
| Maikhuri, JP | 1 |
| Wahajuddin, M | 1 |
| Konwar, R | 1 |
| Gupta, G | 1 |
| Sharma, VL | 1 |
| Bourdeau-Heller, J | 1 |
| Oberley, TD | 1 |
| Vaur, S | 1 |
| Sartor, P | 1 |
| Dufy-Barbe, L | 1 |
| Pilatus, U | 1 |
| Aboagye, E | 1 |
| Artemov, D | 1 |
| Mori, N | 1 |
| Ackerstaff, E | 1 |
| Bhujwalla, ZM | 1 |
| Huang, JK | 2 |
| Jan, CR | 2 |
| Jiann, BP | 1 |
| Lu, YC | 1 |
| Chang, HT | 1 |
8 other studies available for carbonyl cyanide m-chlorophenyl hydrazone and Cancer of Prostate
| Article | Year |
|---|---|
Design and synthesis of novel bicalutamide and enzalutamide derivatives as antiproliferative agents for the treatment of prostate cancer.
Topics: Anilides; Antineoplastic Agents; Benzamides; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Che | 2016 |
Rational design and synthesis of novel anti-prostate cancer agents bearing a 3,5-bis-trifluoromethylphenyl moiety.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug | 2016 |
Synthesis and biological evaluation of some novel triazole hybrids of curcumin mimics and their selective anticancer activity against breast and prostate cancer cell lines.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cell Cycle Checkpoin | 2016 |
Prostate carcinoma cells selected by long-term exposure to reduced oxygen tension show remarkable biochemical plasticity via modulation of superoxide, HIF-1alpha levels, and energy metabolism.
Topics: Adenosine Triphosphate; Antimycin A; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Hypoxia; Cell L | 2007 |
Calcium store depletion induced by mitochondrial uncoupling in prostatic cells.
Topics: Adenosine Triphosphate; Antimycin A; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membra | 2000 |
Real-time measurements of cellular oxygen consumption, pH, and energy metabolism using nuclear magnetic resonance spectroscopy.
Topics: Adenosine Triphosphate; Animals; Breast Neoplasms; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Energy | 2001 |
Mechanism of estrogens-induced increases in intracellular Ca(2+) in PC3 human prostate cancer cells.
Topics: Antineoplastic Agents, Hormonal; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Diethylstilbest | 2001 |
Effect of clomiphene on Ca(2+) movement in human prostate cancer cells.
Topics: Brefeldin A; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Survival; Clomiphene; Dose-Res | 2002 |