carbonyl cyanide m-chlorophenyl hydrazone has been researched along with Bone Cancer in 1 studies
Carbonyl Cyanide m-Chlorophenyl Hydrazone: A proton ionophore. It is commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.
CCCP : A member of the class of monochlorobenzenes that is benzene substituted by 2-(1,3-dinitrilopropan-2-ylidene)hydrazinyl and chloro groups at positions 1 and 3, respectively. It is a mitochondrial depolarizing agent that induces reactive oxygen species mediated cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have previously shown that treatment of human osteosarcoma cells with the protonophore m-chlorophenylhydrazone (CCCP) for 6 h induces MPT and mitochondrial swelling without significant cell death." | 1.31 | The protonophore CCCP induces mitochondrial permeability transition without cytochrome c release in human osteosarcoma cells. ( Lim, ML; Minamikawa, T; Nagley, P, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lim, ML | 1 |
| Minamikawa, T | 1 |
| Nagley, P | 1 |
1 other study available for carbonyl cyanide m-chlorophenyl hydrazone and Bone Cancer
| Article | Year |
|---|---|
The protonophore CCCP induces mitochondrial permeability transition without cytochrome c release in human osteosarcoma cells.
Topics: Bone Neoplasms; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membrane Permeability; Cytochrome c | 2001 |