carbonyl cyanide m-chlorophenyl hydrazone has been researched along with Anoxemia in 12 studies
Carbonyl Cyanide m-Chlorophenyl Hydrazone: A proton ionophore. It is commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.
CCCP : A member of the class of monochlorobenzenes that is benzene substituted by 2-(1,3-dinitrilopropan-2-ylidene)hydrazinyl and chloro groups at positions 1 and 3, respectively. It is a mitochondrial depolarizing agent that induces reactive oxygen species mediated cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypoxia/reperfusion injury is a major clinical problem." | 5.29 | Cyclosporine A protects mitochondria in an in vitro model of hypoxia/reperfusion injury. ( Gogvadze, V; Richter, C, 1993) |
| " MMP was measured by JC-1 in isolated pulmonary arterial smooth muscle cells (PASMCs) of patients with PH and animals with PH induced by exposure to monocrotaline (MCT) or chronic hypoxia." | 3.79 | Mitochondrial hyperpolarization in pulmonary vascular remodeling. Mitochondrial uncoupling protein deficiency as disease model. ( Bakr, A; Esfandiary, A; Fuchs, B; Ghofrani, HA; Grimminger, F; Haag, D; Hecker, M; Hoeres, T; Kojonazarov, B; Pak, O; Schermuly, RT; Seeger, W; Sommer, N; Sydykov, A; Veit, F; Waisbrod, S; Weisel, FC; Weissmann, N, 2013) |
| "Cox deficiency is associated with hematopoietic diseases such as tubulopathy and leukodystrophy, but whether and how cox17 functions in hematopoiesis are still unknown." | 1.72 | Zebrafish cox17 modulates primitive erythropoiesis via regulation of mitochondrial metabolism to facilitate hypoxia tolerance. ( Chen, M; Li, L; Liu, JX; Liu, W; Liu, X; Tai, P, 2022) |
| "Subsequent exposure to anoxia, in the continued presence of CCCP, yields little additional acidification, suggesting that proton gradients are normally dissipated under anoxia." | 1.33 | V-ATPase inhibition prevents recovery from anoxia in Artemia franciscana embryos: quiescence signaling through dissipation of proton gradients. ( Covi, JA; Hand, SC; Treleaven, WD, 2005) |
| "Hypoxia/reperfusion injury is a major clinical problem." | 1.29 | Cyclosporine A protects mitochondria in an in vitro model of hypoxia/reperfusion injury. ( Gogvadze, V; Richter, C, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Li, L | 1 |
| Chen, M | 1 |
| Liu, W | 1 |
| Tai, P | 1 |
| Liu, X | 1 |
| Liu, JX | 1 |
| Pak, O | 1 |
| Sommer, N | 1 |
| Hoeres, T | 1 |
| Bakr, A | 1 |
| Waisbrod, S | 1 |
| Sydykov, A | 1 |
| Haag, D | 1 |
| Esfandiary, A | 1 |
| Kojonazarov, B | 1 |
| Veit, F | 1 |
| Fuchs, B | 1 |
| Weisel, FC | 1 |
| Hecker, M | 1 |
| Schermuly, RT | 1 |
| Grimminger, F | 1 |
| Ghofrani, HA | 1 |
| Seeger, W | 1 |
| Weissmann, N | 1 |
| Nakamura, E | 1 |
| Yokoi, T | 1 |
| Fukuta, H | 1 |
| Iida, T | 1 |
| Tanaka, Y | 1 |
| Yamamoto, Y | 1 |
| Suzuki, H | 1 |
| Lukyanetz, EA | 1 |
| Stanika, RI | 1 |
| Koval, LM | 1 |
| Kostyuk, PG | 1 |
| Covi, JA | 1 |
| Treleaven, WD | 1 |
| Hand, SC | 1 |
| Gogvadze, V | 1 |
| Richter, C | 1 |
| Marsh, DC | 1 |
| Vreugdenhil, PK | 1 |
| Mack, VE | 1 |
| Belzer, FO | 1 |
| Southard, JH | 1 |
| Riedinger, HJ | 1 |
| van Betteraey-Nikoleit, M | 1 |
| Hilfrich, U | 1 |
| Eisele, KH | 1 |
| Probst, H | 1 |
| Bing, OH | 1 |
| Brooks, WW | 1 |
| Messer, JV | 1 |
| Shanley, PF | 1 |
| Johnson, GC | 1 |
| Hohl, CM | 1 |
| Altschuld, RA | 1 |
| Marsh, JD | 1 |
| Sweeney, KA | 1 |
12 other studies available for carbonyl cyanide m-chlorophenyl hydrazone and Anoxemia
| Article | Year |
|---|---|
Zebrafish cox17 modulates primitive erythropoiesis via regulation of mitochondrial metabolism to facilitate hypoxia tolerance.
Topics: Adenosine Triphosphate; Animals; beta Catenin; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cytochrome | 2022 |
Mitochondrial hyperpolarization in pulmonary vascular remodeling. Mitochondrial uncoupling protein deficiency as disease model.
Topics: Animals; Benzimidazoles; Carbocyanines; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Disease Models, A | 2013 |
Hypoxia differentially modulates the activity of pacemaker and smooth muscle cells in the guinea pig stomach antrum.
Topics: Animals; Calcium; Calcium Signaling; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Electrophysiological | 2009 |
Intracellular mechanisms of hypoxia-induced calcium increase in rat sensory neurons.
Topics: Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Carbonyl Cyanide m-Ch | 2003 |
V-ATPase inhibition prevents recovery from anoxia in Artemia franciscana embryos: quiescence signaling through dissipation of proton gradients.
Topics: Acid-Base Equilibrium; Animals; Artemia; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Embryo, Nonmamma | 2005 |
Cyclosporine A protects mitochondria in an in vitro model of hypoxia/reperfusion injury.
Topics: Adenosine Diphosphate; Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cyclosporine; Eg | 1993 |
Glycine protects hepatocytes from injury caused by anoxia, cold ischemia and mitochondrial inhibitors, but not injury caused by calcium ionophores or oxidative stress.
Topics: Amino Acids; Animals; Calcimycin; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cold Temperature; Glyci | 1993 |
Oxygen-dependent regulation of in vivo replication of simian virus 40 DNA is modulated by glucose.
Topics: Adenosine Triphosphate; Anti-Bacterial Agents; Antimycin A; Antiviral Agents; Blotting, Southern; Br | 2001 |
Prolongation of tension on reoxygenation following myocardial hypoxia: a possible role for mitochondria in muscle relaxation.
Topics: Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Dinitrophenols; Glycolysis; Heart; Hypoxia; Insu | 1976 |
Calcium and acidosis in renal hypoxia.
Topics: Acidosis; Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Extracellular Space; Hydrogen | 1991 |
Response of isolated adult canine cardiac myocytes to prolonged hypoxia and reoxygenation.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aerobiosis; Anaerobiosis; An | 1991 |
Beta-adrenergic receptor regulation during hypoxia in intact cultured heart cells.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cells | 1989 |