carbonyl cyanide m-chlorophenyl hydrazone has been researched along with Amyotrophic Lateral Sclerosis in 1 studies
Carbonyl Cyanide m-Chlorophenyl Hydrazone: A proton ionophore. It is commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.
CCCP : A member of the class of monochlorobenzenes that is benzene substituted by 2-(1,3-dinitrilopropan-2-ylidene)hydrazinyl and chloro groups at positions 1 and 3, respectively. It is a mitochondrial depolarizing agent that induces reactive oxygen species mediated cell death.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ruan, Y | 1 |
| Hu, J | 1 |
| Che, Y | 1 |
| Liu, Y | 1 |
| Luo, Z | 1 |
| Cheng, J | 1 |
| Han, Q | 1 |
| He, H | 1 |
| Zhou, Q | 1 |
1 other study available for carbonyl cyanide m-chlorophenyl hydrazone and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
CHCHD2 and CHCHD10 regulate mitochondrial dynamics and integrated stress response.
Topics: Amyotrophic Lateral Sclerosis; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; DNA-Binding Prote | 2022 |