carbon tetrachloride has been researched along with Non-alcoholic Fatty Liver Disease in 45 studies
Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Non-alcoholic Fatty Liver Disease: Fatty liver finding without excessive ALCOHOL CONSUMPTION.
Excerpt | Relevance | Reference |
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"Treatment with SR9243 significantly reduced the severity of hepatic inflammation and ameliorated hepatic fibrosis; simultaneously, body weight, serum glucose, and plasma lipid levels were controlled effectively." | 5.48 | Liver X Receptor Inverse Agonist SR9243 Suppresses Nonalcoholic Steatohepatitis Intrahepatic Inflammation and Fibrosis. ( Chang, S; Huang, FZ; Huang, P; Jiang, XL; Kaluba, B; Mao, LF; Tang, XF; Zhang, ZP, 2018) |
" Dangfei Liganning capsules potentially decrease this toxic susceptibility and alleviate liver injury in non-alcoholic fatty liver." | 5.37 | Dangfei liganning capsules attenuate the susceptibility of rat nonalcoholic fatty liver to carbon tetrachloride toxicity. ( Ge, YL; Ji, G; Li, DF; Liu, P; Liu, T; Mao, ZM; Song, HY; Yang, LL; Zhang, L; Zhang, XQ; Zheng, PY, 2011) |
"Here, we examine the impact of housing temperature on steatosis, hepatocellular damage, hepatic inflammation, and fibrosis in NASH diet, methionine and choline deficient diet, and western diet + carbon tetrachloride experimental models of NAFLD in C57BL/6 mice." | 4.31 | Thermoneutral housing shapes hepatic inflammation and damage in mouse models of non-alcoholic fatty liver disease. ( Alarcon, PC; Damen, MSMA; Divanovic, S; Giles, DA; Moreno-Fernandez, ME; Oates, JR; Sawada, K; Stankiewicz, TE; Szabo, S, 2023) |
"Fibrosis is characterized by the excessive deposition of extracellular matrix and crosslinked proteins, in particular collagen and elastin, leading to tissue stiffening and disrupted organ function." | 3.91 | The lysyl oxidase like 2/3 enzymatic inhibitor, PXS-5153A, reduces crosslinks and ameliorates fibrosis. ( Buson, A; Deodhar, M; Findlay, AD; Foot, JS; Greco, A; Jarolimek, W; Joshi, A; Moses, J; Perryman, L; Rayner, B; Schilter, H; Townsend, S; Turner, CI; Yow, TT; Zahoor, A; Zhou, W, 2019) |
" By establishing a simple method of discriminating between apoptosis and necrosis in the liver, we found that necrosis occurred prior to apoptosis at the onset of steatohepatitis in the choline-deficient, ethionine-supplemented (CDE) diet model." | 3.91 | Hepatic ferroptosis plays an important role as the trigger for initiating inflammation in nonalcoholic steatohepatitis. ( Imai, H; Koumura, T; Matsuoka, M; Miyajima, A; Nakano, H; Nakasone, M; Okochi, H; Sakamoto, T; Tanaka, M; Tsuchiya, Y; Tsurusaki, S; Yuet-Yin Kok, C, 2019) |
" C57BL/6N mice were fed a high-fat diet (HFD) to develop obesity and were either administered carbon tetrachloride (CCl4 ) eight times (0." | 3.79 | A high-fat diet and multiple administration of carbon tetrachloride induces liver injury and pathological features associated with non-alcoholic steatohepatitis in mice. ( Ishikawa, F; Kado, S; Kano, M; Kobayashi, T; Kubota, N; Masuoka, N; Miyazaki, K; Nagata, Y, 2013) |
"To study the mechanism of liver injury induced by carbon tetrachloride (CCl(4)) in rats with non-alcoholic fatty liver disease (NAFLD), and the therapeutic effects of the extract mixture of Dangyao (Swertia pseudochinensis Hara) and Shuifeiji (Silybum marianum Gaertn) on NAFLD rats with liver injury." | 3.78 | [Effects of the mixture of Swertia pseudochinensis Hara and Silybum marianum Gaertn extracts on CCl(4)-induced liver injury in rats with non-alcoholic fatty liver disease]. ( Ji, G; Li, DF; Liu, P; Liu, T; Mao, ZM; Song, HY; Yang, LL; Zheng, PY, 2012) |
"Nonalcoholic fatty liver disease (NAFLD) is a continuous diseases spectrum associated with obesity, type 2 diabetes, insulin resistance, and hyperlipidemia." | 2.66 | Rodent Models of Nonalcoholic Fatty Liver Disease. ( Gao, L; Xu, J; Zhong, F; Zhou, X, 2020) |
"Liver fibrosis is a leading indicator for increased mortality and long-term comorbidity in NASH." | 1.91 | Tyrosine kinase receptor B attenuates liver fibrosis by inhibiting TGF-β/SMAD signaling. ( Chen, S; Cheng, J; Dong, L; Fu, R; Han, P; Li, R; Li, S; Liu, Z; Pei, H; Shen, X; Song, G; Song, Y; Wang, H; Wei, J; Wu, J; Yao, Q; Zhang, G; Zhang, S; Zhao, Y; Zhu, C; Zhu, J, 2023) |
"Non-alcoholic fatty liver disease (NAFLD)-related liver fibrosis results in the encapsulation of injured liver parenchyma by a collagenous scar mainly imputable to hepatic stellate cells' activation." | 1.72 | Combination Treatment with Hydroxytyrosol and Vitamin E Improves NAFLD-Related Fibrosis. ( Alisi, A; Bianchi, M; Braghini, MR; Comparcola, D; Condorelli, AG; Conti, LA; Crudele, A; De Stefanis, C; Gurrado, F; Lioci, G; Mosca, A; Nobili, R; Panera, N; Sartorelli, MR; Scoppola, V; Smeriglio, A; Svegliati-Baroni, G; Trombetta, D, 2022) |
"Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in the Western world, and it is closely associated to obesity, type 2 diabetes mellitus, and dyslipidemia." | 1.62 | Δ9-Tetrahydrocannabinolic Acid markedly alleviates liver fibrosis and inflammation in mice. ( Appendino, G; Carmona-Hidalgo, B; García-Martín, A; González-Mariscal, I; Muñoz, E; Prados, ME; Ruiz-Pino, F; Tena-Sempere, M, 2021) |
"Liver fibrosis was attenuated in mice with Tgr5 depletion." | 1.62 | Conjugated secondary 12α-hydroxylated bile acids promote liver fibrogenesis. ( Bian, H; Gao, X; Huang, F; Jia, W; Jiang, R; Liu, P; Liu, Z; Qiu, J; Rajani, C; Sun, B; Wang, X; Wu, Y; Xie, G; Zhang, X; Zhao, A; Zhao, S; Zheng, X, 2021) |
"Non-alcoholic fatty liver disease (NAFLD) may increase the sensitivity to liver injury caused by stimulants such as drugs and poisons." | 1.51 | Jiang-Zhi granules decrease sensitivity to low-dose CCl ( Song, H; Yang, L; Zheng, P; Zhou, Y, 2019) |
"Non-alcoholic steatohepatitis (NASH) is a major cause of chronic liver disease." | 1.51 | New Rat Model of Advanced NASH Mimicking Pathophysiological Features and Transcriptomic Signature of The Human Disease. ( Bosch, J; Boyer-Diaz, Z; Gracia-Sancho, J; Lozano, JJ; Maeso-Díaz, R; Ortega-Ribera, M; Peralta, C, 2019) |
"Furthermore, AZGP1 alleviated NAFLD by blocking TNF-α-mediated inflammation and intracellular lipid deposition, promoting proliferation, and inhibiting apoptosis in LO2 cells." | 1.51 | Zinc-α2-glycoprotein 1 attenuates non-alcoholic fatty liver disease by negatively regulating tumour necrosis factor-α. ( Li, ZH; Liu, T; Luo, SZ; Luo, X; Wu, JC; Xu, MY, 2019) |
"Treatment with SR9243 significantly reduced the severity of hepatic inflammation and ameliorated hepatic fibrosis; simultaneously, body weight, serum glucose, and plasma lipid levels were controlled effectively." | 1.48 | Liver X Receptor Inverse Agonist SR9243 Suppresses Nonalcoholic Steatohepatitis Intrahepatic Inflammation and Fibrosis. ( Chang, S; Huang, FZ; Huang, P; Jiang, XL; Kaluba, B; Mao, LF; Tang, XF; Zhang, ZP, 2018) |
"We tested in patients with suspected nonalcoholic steatohepatitis (NASH) the association of FNDC5 variants, hepatic expression, and circulating irisin with liver damage (F2 to F4 fibrosis as main outcome)." | 1.46 | Fibronectin Type III Domain-Containing Protein 5 rs3480 A>G Polymorphism, Irisin, and Liver Fibrosis in Patients With Nonalcoholic Fatty Liver Disease. ( Cabibi, D; Cammà, C; Craxì, A; Di Marco, V; Dongiovanni, P; Fargion, S; Ferri, N; Fracanzani, AL; Giordano, D; Grimaudo, S; Maggioni, M; Meroni, M; Petta, S; Pierantonelli, I; Pipitone, RM; Ruscica, M; Rychlicki, C; Svegliati-Baroni, G; Valenti, L, 2017) |
"Nonalcoholic fatty liver disease (NAFLD) is a highly prevalent form of human hepatic disease and feeding mice a high-fat, high-caloric (HFHC) diet is a standard model of NAFLD." | 1.42 | Identification of eQTLs for hepatic Xbp1s and Socs3 gene expression in mice fed a high-fat, high-caloric diet. ( Anderson, K; Cheverud, J; Green, RM; Hall, RA; Jafari, N; Kenney-Hunt, J; Lammert, F; Pasricha, S, 2015) |
"Liver cancer is a major health-care concern and its oncogenic mechanisms are still largely unclear." | 1.42 | Hepatocyte-specific Bid depletion reduces tumor development by suppressing inflammation-related compensatory proliferation. ( Eguchi, A; Feldstein, AE; Font-Burgada, J; Johnson, CD; Karin, M; Povero, D; Wree, A, 2015) |
"Non-alcoholic fatty liver disease (NAFLD) is defined as a spectrum of conditions ranging from hepatocellular steatosis to steatohepatitis and fibrosis, progressing to cirrhosis, which occur in the absence of excessive alcohol use." | 1.40 | Fast food diet with CCl4 micro-dose induced hepatic-fibrosis--a novel animal model. ( Chanderasekharan, H; Chheda, TK; Madanahalli, JR; Marikunte, VV; Moolemath, Y; Oommen, AM; Sadasivan, SK; Shivakumar, P, 2014) |
"Our results showed that the induced NAFLD and insulin resistance (IR) were accompanied with hyperglycemia and hyperlipidemia and lowered brain glucose level with elevated ATPase activity, prooxidant status (TBARS level, xanthine oxidase and cytochrome 2E1 activities), and inflammatory markers." | 1.37 | Non-alcoholic fatty liver induces insulin resistance and metabolic disorders with development of brain damage and dysfunction. ( Ghareeb, DA; Hafez, HS; Hussien, HM; Kabapy, NF, 2011) |
"Nonalcoholic fatty liver disease (NAFLD) is one of the most frequent causes of abnormal liver function." | 1.37 | Liver fatty acid composition in mice with or without nonalcoholic fatty liver disease. ( Cao, Y; Fu, Y; Guo, G; Wang, X; Zhang, X, 2011) |
" Dangfei Liganning capsules potentially decrease this toxic susceptibility and alleviate liver injury in non-alcoholic fatty liver." | 1.37 | Dangfei liganning capsules attenuate the susceptibility of rat nonalcoholic fatty liver to carbon tetrachloride toxicity. ( Ge, YL; Ji, G; Li, DF; Liu, P; Liu, T; Mao, ZM; Song, HY; Yang, LL; Zhang, L; Zhang, XQ; Zheng, PY, 2011) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 24 (53.33) | 24.3611 |
2020's | 21 (46.67) | 2.80 |
Authors | Studies |
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Chen, J | 2 |
Martin-Mateos, R | 1 |
Li, J | 3 |
Yin, Z | 1 |
Lu, X | 1 |
Glaser, KJ | 1 |
Mounajjed, T | 1 |
Yashiro, H | 1 |
Siegelman, J | 1 |
Winkelmann, CT | 1 |
Wang, J | 1 |
Ehman, RL | 1 |
Shah, VH | 1 |
Yin, M | 1 |
Márquez-Quiroga, LV | 1 |
Arellanes-Robledo, J | 1 |
Vásquez-Garzón, VR | 1 |
Villa-Treviño, S | 1 |
Muriel, P | 1 |
Wu, B | 1 |
Zheng, X | 2 |
Li, X | 1 |
Wang, C | 1 |
Li, L | 1 |
Tang, Z | 1 |
Cui, H | 1 |
Li, Z | 2 |
Chen, L | 1 |
Ma, X | 1 |
Wang, D | 1 |
Tan, KS | 1 |
Zeng, W | 1 |
Li, S | 2 |
Wang, Y | 3 |
Xu, F | 1 |
Tan, W | 1 |
Panera, N | 1 |
Braghini, MR | 1 |
Crudele, A | 1 |
Smeriglio, A | 1 |
Bianchi, M | 1 |
Condorelli, AG | 1 |
Nobili, R | 1 |
Conti, LA | 1 |
De Stefanis, C | 1 |
Lioci, G | 1 |
Gurrado, F | 1 |
Comparcola, D | 1 |
Mosca, A | 1 |
Sartorelli, MR | 1 |
Scoppola, V | 1 |
Svegliati-Baroni, G | 2 |
Trombetta, D | 1 |
Alisi, A | 1 |
Song, Y | 1 |
Wei, J | 1 |
Li, R | 1 |
Fu, R | 1 |
Han, P | 1 |
Wang, H | 1 |
Zhang, G | 1 |
Chen, S | 1 |
Liu, Z | 2 |
Zhao, Y | 1 |
Zhu, C | 1 |
Zhu, J | 1 |
Zhang, S | 1 |
Pei, H | 1 |
Cheng, J | 1 |
Wu, J | 1 |
Dong, L | 1 |
Song, G | 1 |
Shen, X | 1 |
Yao, Q | 1 |
Oates, JR | 1 |
Sawada, K | 1 |
Giles, DA | 1 |
Alarcon, PC | 1 |
Damen, MSMA | 1 |
Szabo, S | 1 |
Stankiewicz, TE | 1 |
Moreno-Fernandez, ME | 1 |
Divanovic, S | 1 |
Pickich, MB | 1 |
Hargrove, MW | 1 |
Phillips, CN | 1 |
Healy, JC | 1 |
Moore, AN | 1 |
Roberts, MD | 1 |
Martin, JS | 1 |
Yang, L | 1 |
Zhou, Y | 1 |
Song, H | 1 |
Zheng, P | 2 |
Maeso-Díaz, R | 1 |
Boyer-Diaz, Z | 1 |
Lozano, JJ | 1 |
Ortega-Ribera, M | 1 |
Peralta, C | 1 |
Bosch, J | 1 |
Gracia-Sancho, J | 1 |
Liu, T | 3 |
Luo, X | 1 |
Li, ZH | 1 |
Wu, JC | 1 |
Luo, SZ | 1 |
Xu, MY | 1 |
Zhong, F | 1 |
Zhou, X | 2 |
Xu, J | 1 |
Gao, L | 1 |
Fishman, P | 1 |
Cohen, S | 1 |
Itzhak, I | 1 |
Amer, J | 1 |
Salhab, A | 1 |
Barer, F | 1 |
Safadi, R | 1 |
Hammoutene, A | 1 |
Biquard, L | 1 |
Lasselin, J | 1 |
Kheloufi, M | 1 |
Tanguy, M | 1 |
Vion, AC | 1 |
Mérian, J | 1 |
Colnot, N | 1 |
Loyer, X | 1 |
Tedgui, A | 1 |
Codogno, P | 1 |
Lotersztajn, S | 1 |
Paradis, V | 1 |
Boulanger, CM | 1 |
Rautou, PE | 1 |
Campos, G | 1 |
Schmidt-Heck, W | 1 |
De Smedt, J | 1 |
Widera, A | 1 |
Ghallab, A | 1 |
Pütter, L | 1 |
González, D | 1 |
Edlund, K | 1 |
Cadenas, C | 1 |
Marchan, R | 1 |
Guthke, R | 1 |
Verfaillie, C | 1 |
Hetz, C | 1 |
Sachinidis, A | 1 |
Braeuning, A | 1 |
Schwarz, M | 1 |
Weiß, TS | 1 |
Banhart, BK | 1 |
Hoek, J | 1 |
Vadigepalli, R | 1 |
Willy, J | 1 |
Stevens, JL | 1 |
Hay, DC | 1 |
Hengstler, JG | 1 |
Godoy, P | 1 |
Terkelsen, MK | 1 |
Bendixen, SM | 1 |
Hansen, D | 1 |
Scott, EAH | 1 |
Moeller, AF | 1 |
Nielsen, R | 1 |
Mandrup, S | 1 |
Schlosser, A | 1 |
Andersen, TL | 1 |
Sorensen, GL | 1 |
Krag, A | 1 |
Natarajan, KN | 1 |
Detlefsen, S | 1 |
Dimke, H | 1 |
Ravnskjaer, K | 1 |
Xu, Y | 1 |
Cai, Z | 1 |
Wang, X | 3 |
Ren, Q | 1 |
Zhou, Z | 2 |
Xie, R | 1 |
You, S | 1 |
Cui, AM | 1 |
Hashmi, SF | 1 |
Zhang, X | 3 |
Nadolny, C | 1 |
Chen, Y | 2 |
Chen, Q | 1 |
Bush, X | 1 |
Hurd, Z | 1 |
Ali, W | 1 |
Qin, G | 1 |
Deng, R | 1 |
Shi, W | 1 |
Zhang, C | 1 |
Jin, H | 1 |
Zeng, Z | 1 |
Wei, L | 1 |
Tian, Y | 1 |
Zhang, D | 1 |
Sun, G | 1 |
Xu, H | 2 |
Zhao, Q | 2 |
Song, N | 2 |
Yan, Z | 2 |
Lin, R | 1 |
Wu, S | 2 |
Jiang, L | 1 |
Hong, S | 2 |
Xie, J | 2 |
Zhou, H | 1 |
Wang, R | 2 |
Jiang, X | 2 |
Carmona-Hidalgo, B | 1 |
González-Mariscal, I | 1 |
García-Martín, A | 1 |
Prados, ME | 1 |
Ruiz-Pino, F | 1 |
Appendino, G | 1 |
Tena-Sempere, M | 1 |
Muñoz, E | 1 |
Xie, G | 1 |
Jiang, R | 1 |
Liu, P | 3 |
Zhao, A | 1 |
Wu, Y | 1 |
Huang, F | 1 |
Rajani, C | 1 |
Qiu, J | 1 |
Zhao, S | 1 |
Bian, H | 1 |
Gao, X | 2 |
Sun, B | 1 |
Jia, W | 1 |
Liu, C | 1 |
Dou, B | 1 |
Huang, J | 1 |
Huang, L | 2 |
Fan, S | 1 |
Huang, C | 1 |
Yang, S | 1 |
Wang, L | 2 |
Wang, T | 1 |
Yang, C | 1 |
Oldenburger, A | 1 |
Birk, G | 1 |
Schlepütz, M | 1 |
Broermann, A | 1 |
Stierstorfer, B | 1 |
Pullen, SS | 1 |
Rippmann, JF | 1 |
Liu, G | 1 |
Cui, Z | 1 |
Liu, H | 1 |
Gong, J | 1 |
Wang, A | 1 |
Zhang, J | 1 |
Ma, Q | 1 |
Huang, Y | 1 |
Piao, G | 1 |
Yuan, H | 1 |
Petta, S | 1 |
Valenti, L | 1 |
Ruscica, M | 1 |
Pipitone, RM | 1 |
Dongiovanni, P | 1 |
Rychlicki, C | 1 |
Ferri, N | 1 |
Cammà, C | 1 |
Fracanzani, AL | 1 |
Pierantonelli, I | 1 |
Di Marco, V | 1 |
Meroni, M | 1 |
Giordano, D | 1 |
Grimaudo, S | 1 |
Maggioni, M | 1 |
Cabibi, D | 1 |
Fargion, S | 1 |
Craxì, A | 1 |
Esrefoglu, M | 1 |
Cetin, A | 1 |
Taslidere, E | 1 |
Elbe, H | 1 |
Ates, B | 1 |
Tok, OE | 1 |
Aydin, MS | 1 |
Huang, P | 1 |
Kaluba, B | 1 |
Jiang, XL | 1 |
Chang, S | 1 |
Tang, XF | 1 |
Mao, LF | 1 |
Zhang, ZP | 1 |
Huang, FZ | 1 |
Schilter, H | 1 |
Findlay, AD | 1 |
Perryman, L | 1 |
Yow, TT | 1 |
Moses, J | 1 |
Zahoor, A | 1 |
Turner, CI | 1 |
Deodhar, M | 1 |
Foot, JS | 1 |
Zhou, W | 1 |
Greco, A | 1 |
Joshi, A | 1 |
Rayner, B | 1 |
Townsend, S | 1 |
Buson, A | 1 |
Jarolimek, W | 1 |
Yang, P | 1 |
Tsurusaki, S | 1 |
Tsuchiya, Y | 1 |
Koumura, T | 1 |
Nakasone, M | 1 |
Sakamoto, T | 1 |
Matsuoka, M | 1 |
Imai, H | 1 |
Yuet-Yin Kok, C | 1 |
Okochi, H | 1 |
Nakano, H | 1 |
Miyajima, A | 1 |
Tanaka, M | 1 |
Hu, M | 1 |
Xu, L | 1 |
An, S | 1 |
Tang, Y | 1 |
Liu, R | 1 |
Kubota, N | 1 |
Kado, S | 1 |
Kano, M | 1 |
Masuoka, N | 1 |
Nagata, Y | 1 |
Kobayashi, T | 1 |
Miyazaki, K | 1 |
Ishikawa, F | 1 |
Chheda, TK | 1 |
Shivakumar, P | 1 |
Sadasivan, SK | 1 |
Chanderasekharan, H | 1 |
Moolemath, Y | 1 |
Oommen, AM | 1 |
Madanahalli, JR | 1 |
Marikunte, VV | 1 |
Pasricha, S | 1 |
Kenney-Hunt, J | 1 |
Anderson, K | 1 |
Jafari, N | 1 |
Hall, RA | 1 |
Lammert, F | 1 |
Cheverud, J | 1 |
Green, RM | 1 |
Wree, A | 1 |
Johnson, CD | 1 |
Font-Burgada, J | 1 |
Eguchi, A | 1 |
Povero, D | 1 |
Karin, M | 1 |
Feldstein, AE | 1 |
Kopec, AK | 1 |
Joshi, N | 1 |
Luyendyk, JP | 1 |
Yano, S | 1 |
Hisanaga, A | 1 |
He, X | 1 |
He, J | 1 |
Sakao, K | 1 |
Hou, DX | 1 |
Carino, A | 1 |
Cipriani, S | 1 |
Marchianò, S | 1 |
Biagioli, M | 1 |
Santorelli, C | 1 |
Donini, A | 1 |
Zampella, A | 1 |
Monti, MC | 1 |
Fiorucci, S | 1 |
Baeck, C | 1 |
Wehr, A | 1 |
Karlmark, KR | 1 |
Heymann, F | 1 |
Vucur, M | 1 |
Gassler, N | 1 |
Huss, S | 1 |
Klussmann, S | 1 |
Eulberg, D | 1 |
Luedde, T | 1 |
Trautwein, C | 1 |
Tacke, F | 1 |
Ghareeb, DA | 1 |
Hafez, HS | 1 |
Hussien, HM | 1 |
Kabapy, NF | 1 |
Cao, Y | 1 |
Fu, Y | 1 |
Guo, G | 1 |
Mao, ZM | 2 |
Song, HY | 2 |
Yang, LL | 2 |
Li, DF | 2 |
Zheng, PY | 2 |
Ji, G | 2 |
Zhang, L | 1 |
Ge, YL | 1 |
Zhang, XQ | 1 |
3 reviews available for carbon tetrachloride and Non-alcoholic Fatty Liver Disease
Article | Year |
---|---|
Models of nonalcoholic steatohepatitis potentiated by chemical inducers leading to hepatocellular carcinoma.
Topics: Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Diet, High-Fat; Diethylnitrosamine; Diseas | 2022 |
Rodent Models of Nonalcoholic Fatty Liver Disease.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Cholesterol, Dietary; Combined Modality Therapy; Diet, | 2020 |
Role of hemostatic factors in hepatic injury and disease: animal models de-liver.
Topics: Animals; Bile Ducts; Blood Coagulation; Blood Coagulation Disorders; Carbon Tetrachloride; Chemical | 2016 |
42 other studies available for carbon tetrachloride and Non-alcoholic Fatty Liver Disease
Article | Year |
---|---|
Multiparametric magnetic resonance imaging/magnetic resonance elastography assesses progression and regression of steatosis, inflammation, and fibrosis in alcohol-associated liver disease.
Topics: Animals; Carbon Tetrachloride; Collagen; Disease Models, Animal; Disease Progression; Elasticity Ima | 2021 |
Design, synthesis and activity evaluation of prodrug form JBP485 and Vitamin E for alleviation of NASH.
Topics: Animals; Body Weight; Carbon Tetrachloride; Dose-Response Relationship, Drug; Drug Design; Fibrosis; | 2022 |
Hepatocellular BChE as a therapeutic target to ameliorate hypercholesterolemia through PRMT5 selective degradation to restore LDL receptor transcription.
Topics: Amino Acid Sequence; Animals; Butyrylcholinesterase; Carbon Tetrachloride; Hep G2 Cells; Hepatocytes | 2022 |
Combination Treatment with Hydroxytyrosol and Vitamin E Improves NAFLD-Related Fibrosis.
Topics: Animals; Carbon Tetrachloride; Fibrosis; Liver; Liver Cirrhosis; Mice; Non-alcoholic Fatty Liver Dis | 2022 |
Tyrosine kinase receptor B attenuates liver fibrosis by inhibiting TGF-β/SMAD signaling.
Topics: Animals; Carbon Tetrachloride; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Mice; Non-alcoholic F | 2023 |
Thermoneutral housing shapes hepatic inflammation and damage in mouse models of non-alcoholic fatty liver disease.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Choline; Disease Models, Animal; Housing; Infla | 2023 |
Effect of curcumin supplementation on serum expression of select cytokines and chemokines in a female rat model of nonalcoholic steatohepatitis.
Topics: Animals; Anti-Inflammatory Agents; Carbon Tetrachloride; Chemokine CCL5; Chemokine CX3CL1; Curcumin; | 2019 |
Jiang-Zhi granules decrease sensitivity to low-dose CCl
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Diet, High-Fat; Drugs, Chines | 2019 |
New Rat Model of Advanced NASH Mimicking Pathophysiological Features and Transcriptomic Signature of The Human Disease.
Topics: Animals; Carbon Tetrachloride; Diet, High-Fat; Disease Models, Animal; Disease Progression; Fatty Li | 2019 |
Zinc-α2-glycoprotein 1 attenuates non-alcoholic fatty liver disease by negatively regulating tumour necrosis factor-α.
Topics: Adipokines; Animals; Carbon Tetrachloride; Carrier Proteins; Diet, High-Fat; Disease Models, Animal; | 2019 |
The A3 adenosine receptor agonist, namodenoson, ameliorates non‑alcoholic steatohepatitis in mice.
Topics: Actins; Adenosine A3 Receptor Agonists; Adiponectin; Animals; Carbon Tetrachloride; Disease Models, | 2019 |
A defect in endothelial autophagy occurs in patients with non-alcoholic steatohepatitis and promotes inflammation and fibrosis.
Topics: Adult; Animals; Apoptosis; Autophagy; Autophagy-Related Protein 5; Carbon Tetrachloride; Cells, Cult | 2020 |
Inflammation-associated suppression of metabolic gene networks in acute and chronic liver disease.
Topics: Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury, Ch | 2020 |
Transcriptional Dynamics of Hepatic Sinusoid-Associated Cells After Liver Injury.
Topics: Animals; Biopsy; Capillaries; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease | 2020 |
Discovery of novel dual PPARα/δ agonists based on benzimidazole scaffold for the treatment of non-alcoholic fatty liver disease.
Topics: Administration, Oral; Animals; Benzimidazoles; Carbon Tetrachloride; Dose-Response Relationship, Dru | 2020 |
Dysregulation of bile acids increases the risk for preterm birth in pregnant women.
Topics: Adolescent; Adult; Animals; Bile Acids and Salts; Carbon Tetrachloride; Cholic Acid; Disease Models, | 2020 |
Isolation and purification of immune cells from the liver.
Topics: Animals; Carbon Tetrachloride; Cell Separation; Chemical and Drug Induced Liver Injury; Collagenases | 2020 |
AdipoR1/AdipoR2 dual agonist recovers nonalcoholic steatohepatitis and related fibrosis via endoplasmic reticulum-mitochondria axis.
Topics: Adenylate Kinase; Alanine Transaminase; Animals; Carbon Tetrachloride; Diet, High-Fat; Disease Model | 2020 |
Δ9-Tetrahydrocannabinolic Acid markedly alleviates liver fibrosis and inflammation in mice.
Topics: Animals; Cannabis; Carbon Tetrachloride; Diet, High-Fat; Dronabinol; Gene Expression Regulation; Hep | 2021 |
Conjugated secondary 12α-hydroxylated bile acids promote liver fibrogenesis.
Topics: Animals; Bile Acids and Salts; Biomarkers; Carbon Tetrachloride; Case-Control Studies; Cell Line; Di | 2021 |
Isotschimgine alleviates nonalcoholic steatohepatitis and fibrosis via FXR agonism in mice.
Topics: Animals; Carbon Tetrachloride; Chenodeoxycholic Acid; Diet; Inflammation; Liver; Liver Cirrhosis; Ma | 2021 |
Antioxidant characteristics and hepatoprotective effects of a formula derived from Maydis stigma, Nelumbo nucifera and Taraxacum officinale against carbon tetrachloride-induced hepatic damage in rats.
Topics: Animals; Antioxidants; Biomarkers; Carbon Tetrachloride; Cell Proliferation; Chemical and Drug Induc | 2020 |
Modulation of vascular contraction via soluble guanylate cyclase signaling in a novel ex vivo method using rat precision-cut liver slices.
Topics: Adenosine Triphosphate; Animals; Blood Vessels; Carbon Tetrachloride; Endothelin-1; Ketanserin; Live | 2021 |
Corosolic acid ameliorates non-alcoholic steatohepatitis induced by high-fat diet and carbon tetrachloride by regulating TGF-β1/Smad2, NF-κB, and AMPK signaling pathways.
Topics: AMP-Activated Protein Kinases; Animals; Carbon Tetrachloride; Diet, High-Fat; Liver; Liver Cirrhosis | 2021 |
Fibronectin Type III Domain-Containing Protein 5 rs3480 A>G Polymorphism, Irisin, and Liver Fibrosis in Patients With Nonalcoholic Fatty Liver Disease.
Topics: Adult; Animals; Carbon Tetrachloride; Case-Control Studies; Diet, High-Fat; Female; Fibronectins; Ge | 2017 |
Therapeutic effects of melatonin and quercetin in improvement of hepatic steatosis in rats through supression of oxidative damage.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Female; Hemorrhage; Inflammation; Liver; Liver Cirrhosi | 2017 |
Liver X Receptor Inverse Agonist SR9243 Suppresses Nonalcoholic Steatohepatitis Intrahepatic Inflammation and Fibrosis.
Topics: Animals; Bile Ducts; Blood Glucose; Body Weight; Carbon Tetrachloride; Cytokines; Hepatocytes; Infla | 2018 |
The lysyl oxidase like 2/3 enzymatic inhibitor, PXS-5153A, reduces crosslinks and ameliorates fibrosis.
Topics: Amino Acid Oxidoreductases; Animals; Carbon Tetrachloride; Collagen; Cross-Linking Reagents; Elastin | 2019 |
Rapeseed Protein-Derived Antioxidant Peptide RAP Ameliorates Nonalcoholic Steatohepatitis and Related Metabolic Disorders in Mice.
Topics: Animals; Antioxidants; Brassica rapa; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; | 2019 |
Hepatic ferroptosis plays an important role as the trigger for initiating inflammation in nonalcoholic steatohepatitis.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Chromans; Cytokines; Diet; Ethionine; Ferroptosis; Hepatit | 2019 |
Relaxin gene delivery mitigates liver metastasis and synergizes with check point therapy.
Topics: Animals; B7-H1 Antigen; Carbon Tetrachloride; Cell Line, Tumor; Disease Progression; Female; Gene Tr | 2019 |
A high-fat diet and multiple administration of carbon tetrachloride induces liver injury and pathological features associated with non-alcoholic steatohepatitis in mice.
Topics: Alanine Transaminase; Animals; Apoptosis; Carbon Tetrachloride; Diet, High-Fat; Disease Models, Anim | 2013 |
Fast food diet with CCl4 micro-dose induced hepatic-fibrosis--a novel animal model.
Topics: Animals; Carbon Tetrachloride; Disease Models, Animal; Fast Foods; Female; Gene Expression Profiling | 2014 |
Identification of eQTLs for hepatic Xbp1s and Socs3 gene expression in mice fed a high-fat, high-caloric diet.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chromosomes; Diet, High-Fat; | 2015 |
Hepatocyte-specific Bid depletion reduces tumor development by suppressing inflammation-related compensatory proliferation.
Topics: Animals; BH3 Interacting Domain Death Agonist Protein; Carbon Tetrachloride; Cell Proliferation; Cel | 2015 |
Polyphenols from Lonicera caerulea L. berry attenuate experimental nonalcoholic steatohepatitis by inhibiting proinflammatory cytokines productions and lipid peroxidation.
Topics: Animals; Carbon Tetrachloride; Cytokines; Disease Models, Animal; Fruit; Heme Oxygenase-1; Interleuk | 2017 |
BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis.
Topics: 3T3-L1 Cells; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Biomarkers; Carbon Tetrachlorid | 2017 |
Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury.
Topics: Acute Disease; Animals; Aptamers, Nucleotide; Bone Marrow Cells; Carbon Tetrachloride; Cells, Cultur | 2012 |
Non-alcoholic fatty liver induces insulin resistance and metabolic disorders with development of brain damage and dysfunction.
Topics: Acetylcholinesterase; Adenosine Triphosphatases; Animals; Blood Glucose; Brain; Brain Chemistry; Car | 2011 |
Liver fatty acid composition in mice with or without nonalcoholic fatty liver disease.
Topics: Animals; Carbon Tetrachloride; Diet, High-Fat; Fatty Acids; Fatty Liver; Lipids; Liver; Male; Mice; | 2011 |
[Effects of the mixture of Swertia pseudochinensis Hara and Silybum marianum Gaertn extracts on CCl(4)-induced liver injury in rats with non-alcoholic fatty liver disease].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug | 2012 |
Dangfei liganning capsules attenuate the susceptibility of rat nonalcoholic fatty liver to carbon tetrachloride toxicity.
Topics: Animals; Capsules; Carbon Tetrachloride; Caspase 3; Cytochrome P-450 CYP2E1; Drugs, Chinese Herbal; | 2011 |