Page last updated: 2024-11-08

carbon tetrachloride and Liver Failure, Acute

carbon tetrachloride has been researched along with Liver Failure, Acute in 76 studies

Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.

Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.

Research Excerpts

ExcerptRelevanceReference
" In this study, we investigated whether 3-genes iPSC transplantation is capable of rescuing carbon tetrachloride (CCl(4))-induced fulminant hepatic failure and hepatic encephalopathy in mice."7.78Improvement of carbon tetrachloride-induced acute hepatic failure by transplantation of induced pluripotent stem cells without reprogramming factor c-Myc. ( Chang, HM; Chang, YL; Chen, HL; Chen, LK; Chen, SY; Chen, YJ; Chiang, CH; Chien, Y; Hsieh, JH; Huo, TI; Jeng, SY; Lai, YH; Li, HY; Liao, YW; Peng, CH, 2012)
"Our data provide the first experimental demonstration that N-acetylcysteine plus deferoxamine reduces mortality rate, decreases oxidative stress, and limits inflammatory infiltration and hepatocyte necrosis induced by CCl4 in the rat."7.72Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced acute hepatic failure in rats. ( Andrades, M; Dal-Pizzol, F; Martins, MR; Menna-Barreto, S; Moreira, JC; Quevedo, J; Reinke, A; Ritter, C; Rocha, J, 2004)
" The bioavailability of bicyclol was increased 3."5.35Pharmacokinetics of bicyclol in rats with acute hepatic failure. ( Hu, J; Li, Y; Sheng, L; Tan, W; Wang, B; Zhao, J, 2008)
"We examined the pharmacokinetic behavior of micafungin, a novel antifungal agent, in rats receiving carbon tetrachloride (CCl4) at a single dose of 2."5.33Pharmacokinetic behavior of micafungin in rats with carbon tetrachloride-induced acute hepatic failure. ( Aimoto, T; Konishi, H; Minouchi, T; Morii, H; Sudo, M; Sumi, M; Yamaji, A, 2005)
"Acute hepatic failure was induced experimentally in rats by intraperitoneal injection of 2."5.31Expression and function of P-glycoprotein in rats with carbon tetrachloride-induced acute hepatic failure. ( Huang, ZH; Murakami, T; Nagai, J; Okochi, A; Takano, M; Yumoyo, R, 2001)
" U-MSCs and DHLCs were injected 48 h after induced fulminant hepatitis (intraperitoneal injection of carbon tetrachloride) in SCID/BALB-c mice."3.81Useful properties of undifferentiated mesenchymal stromal cells and adipose tissue as the source in liver-regenerative therapy studied in an animal model of severe acute fulminant hepatitis. ( Boin, I; da Silva Santos Duarte, A; Escanhoela, C; Kharmandayan, P; Latuf-Filho, P; Malheiros Luzo, ÂC; Manzini, BM; Olalla Saad, ST; Ramos, AL; Sankaramanivel, S, 2015)
" In this study, we investigated whether 3-genes iPSC transplantation is capable of rescuing carbon tetrachloride (CCl(4))-induced fulminant hepatic failure and hepatic encephalopathy in mice."3.78Improvement of carbon tetrachloride-induced acute hepatic failure by transplantation of induced pluripotent stem cells without reprogramming factor c-Myc. ( Chang, HM; Chang, YL; Chen, HL; Chen, LK; Chen, SY; Chen, YJ; Chiang, CH; Chien, Y; Hsieh, JH; Huo, TI; Jeng, SY; Lai, YH; Li, HY; Liao, YW; Peng, CH, 2012)
"The function of multidrug resistance-associated protein 2 (Mrp2) in the intestine and liver, as well as intestinal Mrp2 expression, was analyzed in CCl(4)-induced acute hepatic failure rats with hyperbilirubinemia."3.73Function of multidrug resistance-associated protein 2 in acute hepatic failure rats. ( Murakami, T; Nagai, J; Takano, M; Yokooji, T; Yumoto, R, 2006)
"The expression and function of P-glycoprotein (P-gp) in the intestine in carbon tetrachloride-induced acute hepatic failure (AHF) were evaluated in rats."3.72Differential effect of acute hepatic failure on in vivo and in vitro P-glycoprotein functions in the intestine. ( Murakami, T; Takano, M; Yumoto, R, 2003)
"Our data provide the first experimental demonstration that N-acetylcysteine plus deferoxamine reduces mortality rate, decreases oxidative stress, and limits inflammatory infiltration and hepatocyte necrosis induced by CCl4 in the rat."3.72Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced acute hepatic failure in rats. ( Andrades, M; Dal-Pizzol, F; Martins, MR; Menna-Barreto, S; Moreira, JC; Quevedo, J; Reinke, A; Ritter, C; Rocha, J, 2004)
"Hepatorenal syndrome is still one of the most important challenges of medicine in the 21st century."2.41[Hepatorenal syndrome in view of experimental studies]. ( Saracyn, M, 2002)
"Acute liver failure is a critical condition characterized by global hepatocyte death and often time needs a liver transplantation."1.48Mesenchymal Stem Cell/Red Blood Cell-Inspired Nanoparticle Therapy in Mice with Carbon Tetrachloride-Induced Acute Liver Failure. ( Allen, T; Cheng, K; Cores, J; Dinh, PU; Freytes, DO; Hensley, MT; Hu, S; Huang, K; Li, Z; Liang, H; Qiao, L; Shao, C; Shen, D; Su, T; Vandergriff, AC; Wrona, EA; Xing, J; Yu, Z; Zeng, Q; Zhang, H, 2018)
"In addition, a lethal CCl₄-induced acute liver failure model offers a survival benefit in oroxylin A treated WT mice."1.39Oroxylin A accelerates liver regeneration in CCl₄-induced acute liver injury mice. ( Chen, H; Chen, Y; Li, M; Liu, B; Liu, J; Zeng, G; Zhang, Q; Zhu, R, 2013)
"Although acute liver failure is a rare disease, its presence is associated with high morbidity and mortality in affected patients."1.38The chemokine receptor CXCR3 limits injury after acute toxic liver damage. ( Berres, ML; Gassler, N; Heinrichs, D; Nellen, A; Sahin, H; Schmitz, P; Streetz, KL; Trautwein, C; Wasmuth, HE; Zaldivar, MM, 2012)
"CCl₄-induced acute liver failure model offers a survival benefit in baicalein-treated mice."1.38Hepatoprotective effects of baicalein against CCl₄-induced acute liver injury in mice. ( Huang, HL; Li, JJ; Liu, B; Wang, FY; Wang, YJ; Zhang, QY; Zhu, RZ, 2012)
" Both acute hepatic and renal failure resulted in significantly increased area under the curve (AUC), prolonged elimination half-life (t(1/2β)), and reduced total body clearance (Cl(tot)) compared with respective controls (P<0."1.37Effects of acute hepatic and renal failure on pharmacokinetics of flunixin meglumine in rats. ( Hwang, YH; Yun, HI, 2011)
"Transplantation of hepatic stem cells combined with heparin can promote the liver recovery in rats with acute liver injury induced by CCl4."1.37[Treatment of acute liver injury by intrasplenic transplantation of hepatic stem cells combined with heparin in rats]. ( Dong, J; Gong, Y; Huang, Z; Ouyang, M; Shen, H; Zeng, S, 2011)
"Fulminant hepatitis or acute liver failure (ALF), initiated by viral infection or hepatic toxin, is a devastating medical complication without effective therapeutic treatment."1.35Contribution of hepatic stellate cells and matrix metalloproteinase 9 in acute liver failure. ( Han, YP; Yan, C; Zhou, L, 2008)
"This work characterized the metabolism disorders of acute liver failure (ALF) induced by carbon tetrachloride (CCl(4)) in a mouse model with different dosage of intoxication (100, 500 and 1000 mg/kg)."1.35A metabonomic characterization of CCl4-induced acute liver failure using partial least square regression based on the GC/MS metabolic profiles of plasma in mice. ( Cheng, Y; Gong, Y; Huang, X; Liu, C; Mao, Y; Qu, H; Shao, L, 2008)
"After transplantation into mice with acute liver failure, ASC-derived hepatocytes can restore such liver functions as ammonia and purine metabolism."1.35Rapid hepatic fate specification of adipose-derived stem cells and their therapeutic potential for liver failure. ( Banas, A; Kato, T; Ochiya, T; Okochi, H; Osaki, M; Takeshita, F; Teratani, T; Tokuhara, M; Yamamoto, Y, 2009)
" The bioavailability of bicyclol was increased 3."1.35Pharmacokinetics of bicyclol in rats with acute hepatic failure. ( Hu, J; Li, Y; Sheng, L; Tan, W; Wang, B; Zhao, J, 2008)
"A novel naringenin-loaded nanoparticles system (NARN) was developed to resolve the restricted bioavailability of naringenin (NAR) and to enhance its hepatoprotective effects in vivo on oral administration."1.35Naringenin-loaded nanoparticles improve the physicochemical properties and the hepatoprotective effects of naringenin in orally-administered rats with CCl(4)-induced acute liver failure. ( Cham, TM; Lin, CC; Lin, LT; Wu, TH; Yen, FL, 2009)
"Liver fibrosis was induced by intraperitoneal injection of CCl(4) for 8 weeks (0."1.35Protective effect of a mixture of Aloe vera and Silybum marianum against carbon tetrachloride-induced acute hepatotoxicity and liver fibrosis. ( Cheon, HJ; Kim, SH; Lee, SM; Oh, ST; Shim, KS; Shin, E; Yun, N, 2009)
"The development of CCl4-induced acute liver failure altered the redox state with a decreased hepatic GSH and increased formation of lipid peroxidative products, which were partially normalized by treatment with heparin-SOD or heparin + SOD."1.35The preventive effects of heparin-superoxide dismutase on carbon tetrachloride-induced acute liver failure and hepatic fibrosis in mice. ( Cao, J; Liu, J; Sun, Y; Tan, H; Wang, F; Zhou, S, 2009)
"The effect of adipose tissue-derived stem cells (ASCs) in combination with heparin transplantation on acute liver failure mice with carbon tetrachloride (CCl(4)) injection was investigated."1.35Cell transplantation of adipose tissue-derived stem cells in combination with heparin attenuated acute liver failure in mice. ( Hamaguchi, M; Hamajima, N; Hayashi, S; Noguchi, H; Oishi, K; Takagi, S; Yukawa, H, 2009)
"Lethal fulminant hepatic failure in nonobese diabetic severe combined immunodeficient mice was induced by carbon tetrachloride gavage."1.35Stem cell therapy for liver disease: parameters governing the success of using bone marrow mesenchymal stem cells. ( Chen, CT; Chuang, CH; Fang, SC; Hung, SP; Kuo, TK; Lee, OK; Shih, YR; Yang, VW, 2008)
"We examined the pharmacokinetic behavior of micafungin, a novel antifungal agent, in rats receiving carbon tetrachloride (CCl4) at a single dose of 2."1.33Pharmacokinetic behavior of micafungin in rats with carbon tetrachloride-induced acute hepatic failure. ( Aimoto, T; Konishi, H; Minouchi, T; Morii, H; Sudo, M; Sumi, M; Yamaji, A, 2005)
"In I and II groups we were modelling acute liver failure by injections of hepatotoxic agent CCL4 (I) and performing 70% hepatectomy (II), III group was served as control group, and IV group served as donors for HPCs."1.33Treatment of toxic liver damage by antihepatocytotoxic serum. ( Didava, G; Lobdjanidze, N; Sujashvili, L; Topuria, D, 2006)
"Retrorsine pretreatment did not affect sensitivity for carbon tetrachloride."1.32Liver regeneration in a retrorsine/CCl4-induced acute liver failure model: do bone marrow-derived cells contribute? ( Aselmann, H; Bahlmann, FH; Dahlke, MH; Jäger, MD; Klempnauer, J; Neipp, M; Piso, P; Popp, FC; Schlitt, HJ, 2003)
"Acute hepatic failure was induced experimentally in rats by intraperitoneal injection of 2."1.31Expression and function of P-glycoprotein in rats with carbon tetrachloride-induced acute hepatic failure. ( Huang, ZH; Murakami, T; Nagai, J; Okochi, A; Takano, M; Yumoyo, R, 2001)
"Acute liver failure was induced in rats by CCl4 administration and its effects on the hepatic Krebs cycle and gluconeogenic fluxes were evaluated in situ by 13C NMR isotopomer analysis of hepatic glucose following infusion of [U-13C]propionate."1.31Hepatic gluconeogenesis and Krebs cycle fluxes in a CCl4 model of acute liver failure. ( Carvalho, RA; Jones, JG; Malloy, CR; McGuirk, C; Sherry, AD, 2002)
" The plasma concentrations of the drug in bile duct-linked rats approximately agreed with the simulation curve by the model, with the peak concentration 6-7 h after dosing."1.30Pharmacokinetic analysis of enterohepatic circulation of etodolac and effect of hepatic and renal injury on the pharmacokinetics. ( Iwaki, M; Kitagawa, T; Ogiso, T; Tanino, T, 1997)

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (2.63)18.2507
2000's32 (42.11)29.6817
2010's36 (47.37)24.3611
2020's6 (7.89)2.80

Authors

AuthorsStudies
Kakizaki, M1
Yamamoto, Y2
Nakayama, S1
Kameda, K1
Nagashima, E1
Ito, M1
Suyama, T1
Matsuzaki, Y1
Chiba, T1
Sumiyoshi, H1
Inagaki, Y1
Kotani, A1
Li, S2
Wang, J1
Jiang, B1
Jiang, J1
Luo, L2
Zheng, B1
Si, W1
Rodimova, S1
Mozherov, A1
Elagin, V1
Karabut, M1
Shchechkin, I1
Kozlov, D1
Krylov, D1
Gavrina, A1
Bobrov, N1
Zagainov, V1
Zagaynova, E1
Kuznetsova, D1
Takayama, Y1
Kusamori, K1
Katsurada, Y1
Obana, S1
Itakura, S1
Nishikawa, M1
Yun, H1
Duan, X1
Xiong, W1
Ding, Y1
Wu, X2
Kang, J1
Pu, X1
Yang, Y1
Chen, Z1
Putra, A1
Rosdiana, I1
Darlan, DM1
Alif, I1
Hayuningtyas, F1
Wijaya, I1
Aryanti, R1
Makarim, FR1
Antari, AD1
Fan, X1
Shan, S1
Wu, P1
Lin, W1
Jia, J1
He, F1
Milosavljevic, N1
Gazdic, M1
Simovic Markovic, B1
Arsenijevic, A1
Nurkovic, J1
Dolicanin, Z1
Djonov, V1
Lukic, ML1
Volarevic, V1
Puengel, T1
Krenkel, O1
Kohlhepp, M1
Lefebvre, E1
Luedde, T2
Trautwein, C3
Tacke, F1
Zare, H1
Jamshidi, S1
Dehghan, MM1
Saheli, M1
Piryaei, A1
Park, SR1
Kim, HJ1
Yang, SR1
Park, CH1
Lee, HY1
Hong, IS1
Liang, H1
Huang, K1
Su, T1
Li, Z2
Hu, S1
Dinh, PU1
Wrona, EA1
Shao, C1
Qiao, L2
Vandergriff, AC1
Hensley, MT1
Cores, J1
Allen, T1
Zhang, H2
Zeng, Q1
Xing, J1
Freytes, DO1
Shen, D1
Yu, Z1
Cheng, K1
Urano, Y1
Oda, S1
Tsuneyama, K1
Yokoi, T1
Liu, QW1
Liu, QY1
Li, JY1
Wei, L1
Ren, KK1
Zhang, XC1
Ding, T1
Xiao, L1
Zhang, WJ1
Wu, HY1
Xin, HB1
Liu, F1
Sun, Z2
Hu, P1
Tian, Q1
Xu, Z1
Tian, X1
Chen, M1
Huang, C1
Xu, C1
Zhao, W1
Hao, Y1
Chang, C1
Fan, J1
Zhu, R1
Zeng, G1
Chen, Y2
Zhang, Q1
Liu, B5
Liu, J4
Chen, H1
Li, M1
Sato, A1
Nakashima, H1
Nakashima, M1
Ikarashi, M1
Nishiyama, K1
Kinoshita, M1
Seki, S1
Deng, L1
Liu, G1
Wang, Y1
Tong, M1
Wang, K1
Peng, Y1
Kong, X1
Puviani, L1
Cavallari, G1
Bonaiuto, E1
Cannistrà, M1
Zullo, A1
Pariali, M1
Pisano, A1
Atzeni, F1
Nardo, B1
Zhang, QY3
Yu, LM1
Li, MY1
Zhu, RZ3
Xie, J1
Chen, TM1
Lan, Q1
Dai, D1
Zhang, WD1
Hu, LP1
Manzini, BM1
da Silva Santos Duarte, A1
Sankaramanivel, S1
Ramos, AL1
Latuf-Filho, P1
Escanhoela, C1
Kharmandayan, P1
Olalla Saad, ST1
Boin, I1
Malheiros Luzo, ÂC1
Cubero, FJ1
Zoubek, ME1
Hu, W1
Peng, J1
Zhao, G1
Nevzorova, YA1
Al Masaoudi, M1
Bechmann, LP1
Boekschoten, MV1
Muller, M1
Preisinger, C1
Gassler, N2
Canbay, AE1
Davis, RJ2
Liedtke, C1
Huang, B1
Cheng, X1
Wang, H1
Huang, W1
la Ga Hu, Z1
Wang, D1
Zhang, K1
Xue, Z1
Da, Y1
Zhang, N1
Hu, Y1
Yao, Z1
Gao, F1
Zhang, R1
Amiri, F1
Molaei, S1
Bahadori, M1
Nasiri, F1
Deyhim, MR1
Jalili, MA1
Nourani, MR1
Habibi Roudkenar, M1
Shi, H2
Han, W1
Ren, F1
Chen, D1
Duan, Z1
Ni, S1
Yang, N1
Tang, X1
Zhang, S1
Hu, D1
Lu, M1
Yan, C1
Zhou, L1
Han, YP1
Huang, X1
Shao, L1
Gong, Y2
Mao, Y1
Liu, C1
Qu, H1
Cheng, Y1
Banas, A1
Teratani, T1
Tokuhara, M1
Takeshita, F1
Osaki, M1
Kato, T1
Okochi, H1
Ochiya, T1
Tan, W1
Wang, B1
Zhao, J1
Sheng, L1
Hu, J1
Li, Y1
Yen, FL1
Wu, TH1
Lin, LT1
Cham, TM1
Lin, CC1
Kim, SH1
Cheon, HJ1
Yun, N1
Oh, ST1
Shin, E1
Shim, KS1
Lee, SM1
Tan, H1
Sun, Y1
Zhou, S1
Cao, J1
Wang, F2
Ichi, I1
Kamikawa, C1
Nakagawa, T1
Kobayashi, K1
Kataoka, R1
Nagata, E1
Kitamura, Y1
Nakazaki, C1
Matsura, T1
Kojo, S1
Taira, Z1
Monmasu, H1
Ueda, Y1
Tuñón, MJ1
Alvarez, M1
Culebras, JM1
González-Gallego, J1
Yukawa, H1
Noguchi, H1
Oishi, K1
Takagi, S1
Hamaguchi, M1
Hamajima, N1
Hayashi, S1
Jin, SZ1
Meng, XW1
Sun, X1
Han, MZ1
Liu, BR1
Wang, XH1
Sun, LY1
Huang, Q1
Zhao, RB1
Ban, X1
Yu, HY1
Yu, HW1
Hou, W1
Piao, ZF1
Zhang, HY1
Liu, Z1
Meng, QH1
Pritchard, MT1
Cohen, JI1
Roychowdhury, S1
Pratt, BT1
Nagy, LE1
Yan, YB1
Song, H1
Zhong, BS1
Wang, ZY1
Ying, SJ1
Mark, AL1
Warren, DS1
Lonze, BE1
Knabel, MK1
Melville Williams, GM1
Locke, JE1
Montgomery, RA1
Cameron, AM1
Hwang, YH1
Yun, HI1
Huang, Z2
Zeng, S1
Ouyang, M1
Dong, J1
Shen, H1
Hongbo, S1
Yu, C1
Ming, K1
Honglin, S1
Ping, HY1
Ping, DZ1
Zaldivar, MM1
Berres, ML1
Sahin, H1
Nellen, A1
Heinrichs, D1
Schmitz, P1
Streetz, KL1
Wasmuth, HE1
Chang, HM1
Liao, YW1
Chiang, CH1
Chen, YJ1
Lai, YH1
Chang, YL1
Chen, HL1
Jeng, SY1
Hsieh, JH1
Peng, CH1
Li, HY1
Chien, Y1
Chen, SY1
Chen, LK1
Huo, TI1
Zhu, G1
Sun, C1
Zhang, J1
Zhang, Y2
Ye, C1
Wang, X1
Ilghari, D1
Li, X1
Jiang, W1
Gao, M1
Sun, S1
Bi, A1
Xin, Y1
Han, X1
Wang, L1
Yin, Z1
Shizhu, J1
Xiangwei, M1
Xun, S1
Mingzi, H1
Bingrong, L1
Dexia, K1
Xinghong, W1
Fenghua, P1
Domitrović, R1
Skoda, M1
Vasiljev Marchesi, V1
Cvijanović, O1
Pernjak Pugel, E1
Stefan, MB1
Huang, HL1
Wang, YJ1
Wang, FY1
Li, JJ1
Jeong, HG1
You, HJ1
Park, SJ1
Moon, AR1
Chung, YC1
Kang, SK1
Chun, HK1
Saracyn, M1
Yumoto, R2
Murakami, T4
Takano, M3
Dahlke, MH1
Popp, FC1
Bahlmann, FH1
Aselmann, H1
Jäger, MD1
Neipp, M1
Piso, P1
Klempnauer, J1
Schlitt, HJ1
Honda, T1
Fukuda, Y1
Nakano, I1
Katano, Y1
Goto, H1
Nagasaki, M1
Sato, Y1
Shimomura, Y1
Taniguchi, M1
Takeuchi, T1
Nakatsuka, R1
Watanabe, T1
Sato, K1
Kucharská, J1
Ulicná, O1
Gvozdjáková, A1
Sumbalová, Z1
Vancová, O1
Bozek, P1
Nakano, M1
Greksák, M1
Ritter, C1
Reinke, A1
Andrades, M1
Martins, MR1
Rocha, J1
Menna-Barreto, S1
Quevedo, J1
Moreira, JC1
Dal-Pizzol, F1
Konishi, H1
Sudo, M1
Sumi, M1
Morii, H1
Minouchi, T1
Aimoto, T1
Yamaji, A1
Topuria, D2
Kakabadze, Z1
Lobdjanidze, N2
Chavchanidze, N1
Didava, G1
Sujashvili, L1
Limaye, PB1
Bhave, VS1
Palkar, PS1
Apte, UM1
Sawant, SP1
Yu, S1
Latendresse, JR1
Reddy, JK1
Mehendale, HM1
Yokooji, T1
Nagai, J2
Henderson, NC1
Pollock, KJ1
Frew, J1
Mackinnon, AC1
Flavell, RA1
Sethi, T1
Simpson, KJ1
Caraceni, P1
Giannone, F1
Catani, L1
Talarico, S1
Pertosa, AM1
Domenicali, M1
Fogli, M1
Principe, A1
Trevisani, F1
Baccarani, M1
Bernardi, M1
Lemoli, RM1
Yoneyama, H1
Kai, Y1
Koyama, J1
Suzuki, K1
Kawachi, H1
Narumi, S1
Ichida, T1
Kuo, TK1
Hung, SP1
Chuang, CH1
Chen, CT1
Shih, YR1
Fang, SC1
Yang, VW1
Lee, OK1
Ogiso, T1
Kitagawa, T1
Iwaki, M1
Tanino, T1
Akira, K1
Negishi, E1
Yamamoto, C1
Baba, S1
Oh, SY1
Lee, CH1
Ku, YS1
Huang, ZH1
Okochi, A1
Yumoyo, R1
Carvalho, RA1
Jones, JG1
McGuirk, C1
Sherry, AD1
Malloy, CR1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Mesenchymal Stem Cell Therapy for Liver Cirrhosis: A Phase I/II Study[NCT03626090]Phase 1/Phase 220 participants (Anticipated)Interventional2018-08-18Recruiting
Phase Ⅰ/Ⅱ Study of Human Umbilical Cord Derived Mesenchymal Stem Cells (UC-MSCs) for Treatment of Liver Failure[NCT01218464]Phase 1/Phase 270 participants (Anticipated)Interventional2009-03-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for carbon tetrachloride and Liver Failure, Acute

ArticleYear
An overview of animal models for investigating the pathogenesis and therapeutic strategies in acute hepatic failure.
    World journal of gastroenterology, 2009, Jul-07, Volume: 15, Issue:25

    Topics: Acetaminophen; Animals; Carbon Tetrachloride; Disease Models, Animal; Galactosamine; Hepatectomy; Hu

2009
[Hepatorenal syndrome in view of experimental studies].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2002, Volume: 13, Issue:77

    Topics: Animals; Carbon Tetrachloride; Hepatorenal Syndrome; Humans; Kidney; Kidney Failure, Chronic; Liver

2002

Other Studies

74 other studies available for carbon tetrachloride and Liver Failure, Acute

ArticleYear
Human hepatocyte-derived extracellular vesicles attenuate the carbon tetrachloride-induced acute liver injury in mice.
    Cell death & disease, 2021, 10-27, Volume: 12, Issue:11

    Topics: Animals; Carbon Tetrachloride; Extracellular Vesicles; Female; Hepatocytes; Humans; Liver Failure, A

2021
Mesenchymal stem cells derived from different perinatal tissues donated by same donors manifest variant performance on the acute liver failure model in mouse.
    Stem cell research & therapy, 2022, 06-03, Volume: 13, Issue:1

    Topics: Animals; Carbon Tetrachloride; Female; Liver Failure, Acute; Mesenchymal Stem Cell Transplantation;

2022
Label-Free Imaging Techniques to Evaluate Metabolic Changes Caused by Toxic Liver Injury in PCLS.
    International journal of molecular sciences, 2023, May-24, Volume: 24, Issue:11

    Topics: Acetaminophen; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Ethanol; Hepatocytes; H

2023
Efficient delivery of mesenchymal stem/stromal cells to injured liver by surface PEGylation.
    Stem cell research & therapy, 2023, 08-22, Volume: 14, Issue:1

    Topics: Animals; Carbon Tetrachloride; Endothelial Cells; Liver Failure, Acute; Mesenchymal Stem Cells; Mice

2023
Exploration of the Hepatoprotective Effect and Mechanism of Swertia mussotii Franch in an Acute Liver Injury Rat Model.
    Combinatorial chemistry & high throughput screening, 2019, Volume: 22, Issue:9

    Topics: Animals; Carbon Tetrachloride; Disease Models, Animal; Drugs, Chinese Herbal; High-Throughput Screen

2019
Intravenous Administration is the Best Route of Mesenchymal Stem Cells Migration in Improving Liver Function Enzyme of Acute Liver Failure.
    Folia medica, 2020, 03-31, Volume: 62, Issue:1

    Topics: 5'-Nucleotidase; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Carbon Tetra

2020
Irradiated and CCl
    Scandinavian journal of immunology, 2020, Volume: 92, Issue:5

    Topics: Animals; Bone Marrow Cells; Carbon Tetrachloride; Cell Differentiation; Cell Proliferation; Cells, C

2020
Mesenchymal stem cells attenuate acute liver injury by altering ratio between interleukin 17 producing and regulatory natural killer T cells.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2017, Volume: 23, Issue:8

    Topics: Animals; Carbon Tetrachloride; CD8-Positive T-Lymphocytes; Cells, Cultured; Coculture Techniques; Di

2017
Differential impact of the dual CCR2/CCR5 inhibitor cenicriviroc on migration of monocyte and lymphocyte subsets in acute liver injury.
    PloS one, 2017, Volume: 12, Issue:9

    Topics: Administration, Oral; Animals; Carbon Tetrachloride; Cell Movement; Cell Polarity; Chemotaxis; Disea

2017
Bone marrow or adipose tissue mesenchymal stem cells: Comparison of the therapeutic potentials in mice model of acute liver failure.
    Journal of cellular biochemistry, 2018, Volume: 119, Issue:7

    Topics: Adipose Tissue; Animals; Carbon Tetrachloride; Cell- and Tissue-Based Therapy; Disease Models, Anima

2018
A novel endogenous damage signal, glycyl tRNA synthetase, activates multiple beneficial functions of mesenchymal stem cells.
    Cell death and differentiation, 2018, Volume: 25, Issue:11

    Topics: Adipose Tissue; Cadherins; Carbon Tetrachloride; Cell Differentiation; Cell Movement; Cell Survival;

2018
Mesenchymal Stem Cell/Red Blood Cell-Inspired Nanoparticle Therapy in Mice with Carbon Tetrachloride-Induced Acute Liver Failure.
    ACS nano, 2018, 07-24, Volume: 12, Issue:7

    Topics: Animals; Apoptosis; Biomimetic Materials; Carbon Tetrachloride; Cell Line; Cell Proliferation; Disea

2018
Comparative hepatic transcriptome analyses revealed possible pathogenic mechanisms of fasiglifam (TAK-875)-induced acute liver injury in mice.
    Chemico-biological interactions, 2018, Dec-25, Volume: 296

    Topics: Animals; Benzofurans; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Concanavalin A;

2018
Therapeutic efficiency of human amniotic epithelial stem cell-derived functional hepatocyte-like cells in mice with acute hepatic failure.
    Stem cell research & therapy, 2018, 11-21, Volume: 9, Issue:1

    Topics: Amnion; Animals; Carbon Tetrachloride; Disease Models, Animal; Epithelial Cells; Hepatocytes; Hetero

2018
Determining the protective effects of Yin-Chen-Hao Tang against acute liver injury induced by carbon tetrachloride using 16S rRNA gene sequencing and LC/MS-based metabolomics.
    Journal of pharmaceutical and biomedical analysis, 2019, Sep-10, Volume: 174

    Topics: Animals; Carbon Tetrachloride; Chromatography, Liquid; Drugs, Chinese Herbal; Gastrointestinal Micro

2019
Comparative analysis of gene expression profiles of acute hepatic failure and that of liver regeneration in rat.
    Gene, 2013, Oct-10, Volume: 528, Issue:2

    Topics: Animals; Carbon Tetrachloride; Cell Cycle Proteins; Cluster Analysis; Energy Metabolism; Immunologic

2013
Oroxylin A accelerates liver regeneration in CCl₄-induced acute liver injury mice.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Carbon Tetrach

2013
Involvement of the TNF and FasL produced by CD11b Kupffer cells/macrophages in CCl4-induced acute hepatic injury.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; Antigens, CD1d; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver Inju

2014
Adipose derived mesenchymal stem cells efficiently rescue carbon tetrachloride-induced acute liver failure in mouse.
    TheScientificWorldJournal, 2014, Volume: 2014

    Topics: Adipose Tissue; Adiposity; Animals; Carbon Tetrachloride; Cells, Cultured; Hyaluronan Receptors; Int

2014
Portal blood arterialization with an extracorporeal device to treat toxic acute hepatic failure in a swine model.
    The International journal of artificial organs, 2014, Volume: 37, Issue:11

    Topics: Animals; Biomarkers; Biopsy; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease M

2014
Phycocyanobilin accelerates liver regeneration and reduces mortality rate in carbon tetrachloride-induced liver injury mice.
    World journal of gastroenterology, 2015, May-14, Volume: 21, Issue:18

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Biomarkers; Carbon Tetrachloride; Cell Proliferation;

2015
Dihydromyricetin alleviates carbon tetrachloride-induced acute liver injury via JNK-dependent mechanism in mice.
    World journal of gastroenterology, 2015, May-14, Volume: 21, Issue:18

    Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Carbon Tetrachloride; Caspase Inhibitors; Cell Prolif

2015
Useful properties of undifferentiated mesenchymal stromal cells and adipose tissue as the source in liver-regenerative therapy studied in an animal model of severe acute fulminant hepatitis.
    Cytotherapy, 2015, Volume: 17, Issue:8

    Topics: Adipose Tissue; Animals; Biomarkers; Bone Marrow Cells; Carbon Tetrachloride; Cell Differentiation;

2015
Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury.
    Gastroenterology, 2016, Volume: 150, Issue:4

    Topics: Acetaminophen; AMP-Activated Protein Kinases; Animals; Carbon Tetrachloride; Case-Control Studies; C

2016
Mesenchymal stem cells and their secreted molecules predominantly ameliorate fulminant hepatic failure and chronic liver fibrosis in mice respectively.
    Journal of translational medicine, 2016, Feb-09, Volume: 14

    Topics: Animals; Apoptosis; Carbon Tetrachloride; Cell Proliferation; Chronic Disease; Culture Media, Condit

2016
Autophagy-Modulated Human Bone Marrow-Derived Mesenchymal Stem Cells Accelerate Liver Restoration in Mouse Models of Acute Liver Failure.
    Iranian biomedical journal, 2016, Volume: 20, Issue:3

    Topics: Animals; Autophagy; Autophagy-Related Protein 7; Bone Marrow Cells; Carbon Tetrachloride; Cell Diffe

2016
Augmenter of liver regeneration protects against carbon tetrachloride-induced liver injury by promoting autophagy in mice.
    Oncotarget, 2017, Feb-21, Volume: 8, Issue:8

    Topics: Animals; Autophagy; Blotting, Western; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury;

2017
Deregulation of Regulatory T Cells in Acute-on-Chronic Liver Failure: A Rat Model.
    Mediators of inflammation, 2017, Volume: 2017

    Topics: Acute-On-Chronic Liver Failure; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon T

2017
Contribution of hepatic stellate cells and matrix metalloproteinase 9 in acute liver failure.
    Liver international : official journal of the International Association for the Study of the Liver, 2008, Volume: 28, Issue:7

    Topics: Animals; Carbon Tetrachloride; Caspase 3; Chemical and Drug Induced Liver Injury; Collagen Type IV;

2008
A metabonomic characterization of CCl4-induced acute liver failure using partial least square regression based on the GC/MS metabolic profiles of plasma in mice.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Jul-15, Volume: 870, Issue:2

    Topics: Animals; Carbon Tetrachloride; Gas Chromatography-Mass Spectrometry; Least-Squares Analysis; Liver F

2008
Rapid hepatic fate specification of adipose-derived stem cells and their therapeutic potential for liver failure.
    Journal of gastroenterology and hepatology, 2009, Volume: 24, Issue:1

    Topics: Adult; Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Biomarkers; Carbon Tetra

2009
Pharmacokinetics of bicyclol in rats with acute hepatic failure.
    Xenobiotica; the fate of foreign compounds in biological systems, 2008, Volume: 38, Issue:11

    Topics: Animals; Biphenyl Compounds; Carbon Tetrachloride; Liver Failure, Acute; Male; Microsomes, Liver; Pr

2008
Naringenin-loaded nanoparticles improve the physicochemical properties and the hepatoprotective effects of naringenin in orally-administered rats with CCl(4)-induced acute liver failure.
    Pharmaceutical research, 2009, Volume: 26, Issue:4

    Topics: Administration, Oral; Animals; Antioxidants; Apoptosis; Carbon Tetrachloride; Caspases; Chemistry, P

2009
Protective effect of a mixture of Aloe vera and Silybum marianum against carbon tetrachloride-induced acute hepatotoxicity and liver fibrosis.
    Journal of pharmacological sciences, 2009, Volume: 109, Issue:1

    Topics: Alanine Transaminase; Aloe; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Complex Mixt

2009
The preventive effects of heparin-superoxide dismutase on carbon tetrachloride-induced acute liver failure and hepatic fibrosis in mice.
    Molecular and cellular biochemistry, 2009, Volume: 327, Issue:1-2

    Topics: Animals; Carbon Tetrachloride; Collagenases; Heparin; Liver Cirrhosis; Liver Failure, Acute; Male; M

2009
Neutral sphingomyelinase-induced ceramide accumulation by oxidative stress during carbon tetrachloride intoxication.
    Toxicology, 2009, Jun-30, Volume: 261, Issue:1-2

    Topics: Alanine Transaminase; Animals; Ascorbic Acid; Aspartate Aminotransferases; Blood Urea Nitrogen; Brai

2009
Innate host-defensive function of a hepatic lipid fraction produced in low-dose carbon tetrachloride-pretreated mice.
    Anticancer research, 2009, Volume: 29, Issue:3

    Topics: Alanine Transaminase; Animals; Calcium; Carbon Tetrachloride; Hepatocytes; Immunity, Innate; Injecti

2009
Cell transplantation of adipose tissue-derived stem cells in combination with heparin attenuated acute liver failure in mice.
    Cell transplantation, 2009, Volume: 18, Issue:5

    Topics: Adipose Tissue; Alanine Transaminase; Animals; Anticoagulants; Aspartate Aminotransferases; Carbon T

2009
Granulocyte colony-stimulating factor enhances bone marrow mononuclear cell homing to the liver in a mouse model of acute hepatic injury.
    Digestive diseases and sciences, 2010, Volume: 55, Issue:10

    Topics: Albumins; Animals; Biopsy; Bone Marrow Cells; Bone Marrow Transplantation; Carbon Tetrachloride; Cel

2010
[The approaches for making acute-on-chronic liver failure in rat].
    Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology, 2009, Volume: 23, Issue:5

    Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Disease Models, Animal; Galactosamine; Humans;

2009
Early growth response-1 attenuates liver injury and promotes hepatoprotection after carbon tetrachloride exposure in mice.
    Journal of hepatology, 2010, Volume: 53, Issue:4

    Topics: Animals; Carbon Tetrachloride; Disease Models, Animal; Early Growth Response Protein 1; Female; Gene

2010
Hepatoprotective effect of an immortal human fetal hepatic cell transplantation on CCL(4)-induced acute liver injury in mice.
    Transplantation proceedings, 2010, Volume: 42, Issue:7

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Carbon Tetrachlori

2010
Stem cell mobilization is life saving in an animal model of acute liver failure.
    Annals of surgery, 2010, Volume: 252, Issue:4

    Topics: Animals; Antigens, CD34; Benzylamines; Carbon Tetrachloride; Cyclams; Female; Flow Cytometry; Granul

2010
Effects of acute hepatic and renal failure on pharmacokinetics of flunixin meglumine in rats.
    Experimental animals, 2011, Volume: 60, Issue:2

    Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Tetrachloride; Clonixi

2011
[Treatment of acute liver injury by intrasplenic transplantation of hepatic stem cells combined with heparin in rats].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2011, Volume: 36, Issue:5

    Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Heparin; Hepatocytes; Liver Failure,

2011
Augmenter of liver regeneration may be a candidate for prognosis of HBV related acute-on-chronic liver failure as a regenerative marker.
    Hepato-gastroenterology, 2012, Volume: 59, Issue:118

    Topics: Analysis of Variance; Animals; Biomarkers; Carbon Tetrachloride; Case-Control Studies; Chemical and

2012
The chemokine receptor CXCR3 limits injury after acute toxic liver damage.
    Laboratory investigation; a journal of technical methods and pathology, 2012, Volume: 92, Issue:5

    Topics: Animals; Carbon Tetrachloride; Hepatocytes; HMGB1 Protein; Humans; Interferon-gamma; Interleukin-1be

2012
Improvement of carbon tetrachloride-induced acute hepatic failure by transplantation of induced pluripotent stem cells without reprogramming factor c-Myc.
    International journal of molecular sciences, 2012, Volume: 13, Issue:3

    Topics: Animals; Antioxidants; Carbon Tetrachloride; Cell Differentiation; Cell Survival; Cell- and Tissue-B

2012
A novel solid-phase site-specific PEGylation enhances the in vitro and in vivo biostabilty of recombinant human keratinocyte growth factor 1.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Aldehydes; Animals; Binding Sites; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyt

2012
Protective effect of L-theanine on carbon tetrachloride-induced acute liver injury in mice.
    Biochemical and biophysical research communications, 2012, Jun-01, Volume: 422, Issue:2

    Topics: Animals; Antioxidants; Apoptosis; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cyclooxygena

2012
Bone marrow mononuclear cell transplant therapy in mice with CCl4-induced acute liver failure.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2012, Volume: 23, Issue:4

    Topics: Alanine Transaminase; Albumins; Animals; Aspartate Aminotransferases; Bone Marrow Transplantation; C

2012
Rosmarinic acid ameliorates acute liver damage and fibrogenesis in carbon tetrachloride-intoxicated mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 51

    Topics: Alanine Transaminase; Animals; Antioxidants; Apoptosis; Carbon Tetrachloride; Carbon Tetrachloride P

2013
Hepatoprotective effects of baicalein against CCl₄-induced acute liver injury in mice.
    World journal of gastroenterology, 2012, Dec-07, Volume: 18, Issue:45

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Carbon Tetrach

2012
Hepatoprotective effects of 18beta-glycyrrhetinic acid on carbon tetrachloride-induced liver injury: inhibition of cytochrome P450 2E1 expression.
    Pharmacological research, 2002, Volume: 46, Issue:3

    Topics: Administration, Topical; Alanine; Animals; Anti-Inflammatory Agents; Ascorbic Acid; Aspartate Aminot

2002
Differential effect of acute hepatic failure on in vivo and in vitro P-glycoprotein functions in the intestine.
    Pharmaceutical research, 2003, Volume: 20, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbon Tetrachloride; Intestinal M

2003
Liver regeneration in a retrorsine/CCl4-induced acute liver failure model: do bone marrow-derived cells contribute?
    Journal of hepatology, 2003, Volume: 39, Issue:3

    Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Carbon Tetrachloride; Cell Line; Chimera; D

2003
Effects of liver failure on branched-chain alpha-keto acid dehydrogenase complex in rat liver and muscle: comparison between acute and chronic liver failure.
    Journal of hepatology, 2004, Volume: 40, Issue:3

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Branched-Chain; Animals; Carbon Tetr

2004
Molecular process in acute liver injury and regeneration induced by carbon tetrachloride.
    Life sciences, 2004, Aug-13, Volume: 75, Issue:13

    Topics: Animals; Blotting, Northern; Blotting, Western; Carbon Tetrachloride; Catalase; DNA Primers; DNA-Bin

2004
Regeneration of coenzyme Q9 redox state and inhibition of oxidative stress by Rooibos tea (Aspalathus linearis) administration in carbon tetrachloride liver damage.
    Physiological research, 2004, Volume: 53, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Aspalathus; Beverages; Carbon Tetrachloride; Liver Failure, A

2004
Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced acute hepatic failure in rats.
    Critical care medicine, 2004, Volume: 32, Issue:10

    Topics: Acetylcysteine; Animals; Antioxidants; Carbon Tetrachloride; Deferoxamine; Hydrocarbons; Inflammatio

2004
Pharmacokinetic behavior of micafungin in rats with carbon tetrachloride-induced acute hepatic failure.
    Biological & pharmaceutical bulletin, 2005, Volume: 28, Issue:3

    Topics: Animals; Carbon Tetrachloride; Echinocandins; Injections, Intravenous; Lipopeptides; Lipoproteins; L

2005
Anti-hepato-cytotoxic serum treatment results in acute liver failure.
    Georgian medical news, 2006, Issue:130

    Topics: Animals; Blood Component Transfusion; Carbon Tetrachloride; Disease Models, Animal; Liver Failure, A

2006
Treatment of toxic liver damage by antihepatocytotoxic serum.
    Georgian medical news, 2006, Issue:133

    Topics: Animals; Blood Component Transfusion; Carbon Tetrachloride; Liver Failure, Acute; Male; Rats; Rats,

2006
Upregulation of calpastatin in regenerating and developing rat liver: role in resistance against hepatotoxicity.
    Hepatology (Baltimore, Md.), 2006, Volume: 44, Issue:2

    Topics: Acetaminophen; Animals; Animals, Newborn; Calcium-Binding Proteins; Calpain; Carbon Tetrachloride; C

2006
Function of multidrug resistance-associated protein 2 in acute hepatic failure rats.
    European journal of pharmacology, 2006, Sep-28, Volume: 546, Issue:1-3

    Topics: Adenosine Triphosphate; Animals; Area Under Curve; ATP-Binding Cassette Transporters; Bile; Bilirubi

2006
Critical role of c-jun (NH2) terminal kinase in paracetamol- induced acute liver failure.
    Gut, 2007, Volume: 56, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anthracenes; Biopsy; Carbon Tetrachloride; Cell De

2007
Effects of granulocyte colony stimulating-factor in a rat model of acute liver injury.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2007, Volume: 39, Issue:10

    Topics: Animals; Carbon Tetrachloride; Colony-Stimulating Factors; Disease Models, Animal; Image Cytometry;

2007
Neutralization of CXCL10 accelerates liver regeneration in carbon tetrachloride-induced acute liver injury.
    Medical molecular morphology, 2007, Volume: 40, Issue:4

    Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Cell Proliferation; Chemokine CXCL10; Female; H

2007
Stem cell therapy for liver disease: parameters governing the success of using bone marrow mesenchymal stem cells.
    Gastroenterology, 2008, Volume: 134, Issue:7

    Topics: Animals; Antioxidants; Bone Marrow Transplantation; Carbon Tetrachloride; Cell Differentiation; Cell

2008
Stem cell therapy for liver disease: parameters governing the success of using bone marrow mesenchymal stem cells.
    Gastroenterology, 2008, Volume: 134, Issue:7

    Topics: Animals; Antioxidants; Bone Marrow Transplantation; Carbon Tetrachloride; Cell Differentiation; Cell

2008
Stem cell therapy for liver disease: parameters governing the success of using bone marrow mesenchymal stem cells.
    Gastroenterology, 2008, Volume: 134, Issue:7

    Topics: Animals; Antioxidants; Bone Marrow Transplantation; Carbon Tetrachloride; Cell Differentiation; Cell

2008
Stem cell therapy for liver disease: parameters governing the success of using bone marrow mesenchymal stem cells.
    Gastroenterology, 2008, Volume: 134, Issue:7

    Topics: Animals; Antioxidants; Bone Marrow Transplantation; Carbon Tetrachloride; Cell Differentiation; Cell

2008
Pharmacokinetic analysis of enterohepatic circulation of etodolac and effect of hepatic and renal injury on the pharmacokinetics.
    Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:4

    Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile; Carbon Tetrachloride; E

1997
Evaluation of liver function by co-administration methodology using 13C-labelled benzoic acid and hippuric acid coupled with nuclear magnetic resonance spectroscopy.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:12

    Topics: Animals; Benzoates; Benzoic Acid; Carbon Isotopes; Carbon Tetrachloride; Feasibility Studies; Hippur

1997
Pharmacokinetics and hepatoprotective effects of 2-methylaminoethyl-4,4'-dimethoxy-5 ,6,5',6'dimethylenedioxybiphenyl-2-carboxylic acid-2'-carboxylate monohydrochloride in rats with CCl4-induced acute hepatic failure.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:9

    Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Hydrocarbons, Chlorinated; Liver; Liver Failure

2000
Expression and function of P-glycoprotein in rats with carbon tetrachloride-induced acute hepatic failure.
    The Journal of pharmacy and pharmacology, 2001, Volume: 53, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; C

2001
Hepatic gluconeogenesis and Krebs cycle fluxes in a CCl4 model of acute liver failure.
    NMR in biomedicine, 2002, Volume: 15, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Isotopes; Carbon Tetrachloride; C

2002