carbon tetrachloride has been researched along with Liver Dysfunction in 685 studies
Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Curcumin attenuates liver injury induced by ethanol, thioacetamide, iron overdose, cholestasis and acute, subchronic and chronic carbon tetrachloride (CCl(4)) intoxication; moreover, it reverses CCl(4) cirrhosis to some extent." | 8.85 | Pharmacological actions of curcumin in liver diseases or damage. ( Muriel, P; Rivera-Espinoza, Y, 2009) |
| " The cytoprotective effect of central TRH on CCl(4)-induced acute hepatocellular necrosis was abolished by hepatic branch vagotomy, atropine, indomethacin and N(G)-nitro-L-arginine methyl ester, but not by 6-hydroxydopamine." | 7.72 | Protective effect of central thyrotropin-releasing hormone on carbon tetrachloride-induced acute hepatocellular necrosis in rats. ( Makino, I; Nakamura, K; Sato, Y; Terano, A; Yoneda, M, 2003) |
| "Endothelial cell damage causes massive hepatic necrosis as a result of fibrin deposition in the hepatic sinusoids." | 7.69 | Use of prostaglandin I2 analog in treatment of massive hepatic necrosis associated with endothelial cell injury and diffuse sinusoidal fibrin deposition. ( Arai, M; Fujiwara, K; Hirata, K; Masaki, N; Matsui, A; Mochida, S; Nagoshi, S; Ohno, A; Tomiya, T; Yamaoka, M, 1995) |
| "Fluphenazine (FP) treatment (50 mg/kg bw, ip in saline) 30 min before or 6 or 10 h after CCl4 administration (1 ml/kg ip in olive oil) significantly prevented the liver necrosis produced by the hepatotoxin at 24 h." | 7.69 | Late protective effects of the anticalmodulin drug fluphenazine on carbon tetrachloride-induced liver necrosis. ( Bernacchi, AS; Castro, GD; Castro, JA; de Ferreyra, EC; San Martin, MF, 1995) |
| "Administration of the radioprotective agent 2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721) at 3 or 6 hr after carbon tetrachloride (CCl4) administration significantly prevented the liver necrosis produced by the hepatotoxin at 24 hr." | 7.69 | Radioprotectors as late preventive agents against carbon tetrachloride induced liver necrosis: protection by 2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721). ( Castro, JA; de Castro, CR; Valles, EG, 1995) |
| "Hepatic granulomas induced by a single or several subcutaneous injections of carbon tetrachloride (CCl4) in Balb/c mice were examined electronmicroscopically and immunocytochemically." | 7.68 | Granuloma formation in the liver of Balb/c mice intoxicated with carbon tetrachloride. ( Lukita-Atmadja, W; Sato, T; Wake, K, 1993) |
| "Studies in the rat with hepatic necrosis induced by carbon tetrachloride showed that the abnormalities in one-stage coagulation tests and the increased catabolism of fibrinogen were similar to those found in man with acute viral or drug-induced hepatic necrosis." | 7.65 | Experimental hepatic necrosis: studies on coagulation abnormalities, plasma clearance, and organ distribution of 125I-labelled fibrinogen. ( Flute, PT; Pannell, G; Rake, MO; Shilkin, KB; Williams, R, 1973) |
| "Melatonin is a powerful endogenous antioxidant produced by the pineal gland and a variety of other organs and many studies confirm its benefits against oxidative stress including lipid peroxidation, protein mutilation and molecular degeneration in various organs, including the liver." | 6.53 | Melatonin's role in preventing toxin-related and sepsis-mediated hepatic damage: A review. ( Alatorre-Jiménez, MA; Almeida-Souza, P; Cantín-Golet, A; Esteban-Zubero, E; García, JJ; López-Pingarrón, L; Reiter, RJ; Reyes-Gonzales, MC; Ruiz-Ruiz, FJ; Tan, DX, 2016) |
| "Liver fibrosis is a prevalent liver disease that requires rapid and effective treatment prior to its progression to cirrhosis and liver damage." | 5.72 | Oral supplementation of policosanol alleviates carbon tetrachloride-induced liver fibrosis in rats. ( Albogami, SM; Alotaibi, SS; Batiha, GE; Elewa, YHA; Makled, S; Mostafa-Hedeab, G; Yassin, F; Zein, N, 2022) |
| "Quinacrine (QUIN) is a well known inhibitor of PLA2." | 5.29 | Late preventive effects of quinacrine on carbon tetrachloride induced liver necrosis. ( Castro, JA; de Toranzo, EG; González Padrón, A, 1993) |
| " Curcumin attenuates liver injury induced by ethanol, thioacetamide, iron overdose, cholestasis and acute, subchronic and chronic carbon tetrachloride (CCl(4)) intoxication; moreover, it reverses CCl(4) cirrhosis to some extent." | 4.85 | Pharmacological actions of curcumin in liver diseases or damage. ( Muriel, P; Rivera-Espinoza, Y, 2009) |
| " Fibrotic mice received a specific FAP inhibitor (FAPi) at 2 doses orally for 2 weeks during parenchymal fibrosis progression (6 weeks of carbon tetrachloride) and regression (2 weeks off carbon tetrachloride), and with biliary fibrosis (Mdr2-/-)." | 4.31 | Fibroblast Activation Protein Activates Macrophages and Promotes Parenchymal Liver Inflammation and Fibrosis. ( Abe, H; Aslam, M; Jia, JD; Kim, YO; Klein, T; Park, KS; Schuppan, D; Yan, XZ; Yang, AT; You, H; Zhao, XY, 2023) |
| "One of the principles of prevention and non-medicamentous treatment of liver diseases, including hepatitis of different etiology, is the normalization of the diet through the consumption of food with physiologically active ingredients, in particular betulin, which helps to eliminate the causes of metabolic and oxidative disorders within liver cells." | 4.31 | [Effects of triterpenoids in fatty products on liver condition of laboratory animals with acute toxic hepatitis]. ( Averyanova, EV; Chugunova, OV; Mazko, ON; Shkolnikova, MN, 2023) |
| "After one week of injection of carbon tetrachloride-olive oil, the rats in the model group increased their body weight slowly, the abdominal circumference of the model rats continued to increase with time." | 4.12 | Qi Sui Zhu Shui Plaster Inhibits AQP1 and MAPK Signaling Reduces Liver Damage Induced by Cirrhotic Ascites. ( Huang, YL; Li, M; Liu, Y; Song, ZH; Zhang, RZ, 2022) |
| " C57BL/6N mice were fed a high-fat diet (HFD) to develop obesity and were either administered carbon tetrachloride (CCl4 ) eight times (0." | 3.79 | A high-fat diet and multiple administration of carbon tetrachloride induces liver injury and pathological features associated with non-alcoholic steatohepatitis in mice. ( Ishikawa, F; Kado, S; Kano, M; Kobayashi, T; Kubota, N; Masuoka, N; Miyazaki, K; Nagata, Y, 2013) |
| "The present study aims to evaluate the hepatoprotective and antioxidant effects of Hibiscus sabdariffa extract on the carbon tetrachloride (CCl(4))-induced hepatocyte damage in fish and provide evidence as to whether it can be potentially used as a medicine for liver diseases in aquaculture." | 3.77 | Hepatoprotective and antioxidant effects of Hibiscus sabdariffa extract against carbon tetrachloride-induced hepatocyte damage in Cyprinus carpio. ( Cao, L; Jeney, G; Nakao, M; Xu, P; Yin, G, 2011) |
| "The liver injury in the model rat was induced by alpha-naphthylisothiocyanate (ANIT) and carbon tetrachloride (CCl(4) ) respectively, and the effects of Yinchenhao Decoction (, YCHD), a proved effective Chinese medical formula for treating the dampness-heat jaundice syndrome in clinic, on the two liver injury models were evaluated by analyzing the serum level of alanine aminotransferase (ALT), asparate aminotransferase (AST), alkaline phosphatase (ALP), malondialchehyche (MDA), total bilirubin (T-BIL), superoxide dismutase (SOD), glutathione peroxidase (GSH-PX) as well as the ratio of liver weight to body weight." | 3.75 | Comparative study on the protective effects of Yinchenhao Decoction against liver injury induced by alpha-naphthylisothiocyanate and carbon tetrachloride. ( Cao, HX; Jiang, XG; Liu, L; Lu, HT; Sun, H; Sun, WJ; Wang, P; Wang, XJ; Wu, ZM; Zhang, GM; Zhou, J, 2009) |
| " In this study, apolipoprotein E-deficient (ApoE-/-) mice were evaluated to define potential effects of hypercholesterolemia on the severity of carbon tetrachloride (CCl4)-induced liver injury." | 3.75 | Increased susceptibility to exacerbated liver injury in hypercholesterolemic ApoE-deficient mice: potential involvement of oxysterols. ( Arroyo, V; Bataller, R; Camps, J; Clària, J; Ferré, N; González-Périz, A; Guardiola, F; Horrillo, R; Joven, J; López-Parra, M; Martínez-Clemente, M; Planagumà, A; Tres, A, 2009) |
| "MR elastography of the liver was performed in 10 rats with hepatic fibrosis induced by intraperitoneal carbon tetrachloride (CCl(4)) injections and five normal rats." | 3.74 | Hepatic viscoelastic parameters measured with MR elastography: correlations with quantitative analysis of liver fibrosis in the rat. ( Abarca-Quinones, J; Annet, L; Leclercq, I; Peeters, F; Salameh, N; Sinkus, R; Ter Beek, LC; Van Beers, BE, 2007) |
| " The results indicated that long-term VI-28 treatment invariably protected against oxidative tissue damage in the rat models of cerebral/myocardial ischemia-reperfusion injury, CCl4 hepatotoxicity, and gentamicin nephrotoxicity." | 3.74 | Long-term treatment with a Yang-invigorating Chinese herbal formula produces generalized tissue protection against oxidative damage in rats. ( Chen, N; Chiu, PY; Ko, KM; Leung, HY; Poon, MK; Siu, AH, 2008) |
| " Ten weeks of carbon tetrachloride injections caused subacute hepatic damage, manifested as significantly less body weight gain and hepatic protein content, and a higher liver weight, serum aspartate aminotransferase and alanine aminotransferase levels, hepatic malondialdehyde (an index for lipid peroxidation), and hydroxyproline (an index for collagen synthesis) concentrations." | 3.74 | Hepatoprotective effects of Artemisiae capillaris herba and Picrorrhiza rhizoma combinations on carbon tetrachloride-induced subacute liver damage in rats. ( Kim, HH; Ku, SK; Lee, HS, 2008) |
| " The cytoprotective effect of central TRH on CCl(4)-induced acute hepatocellular necrosis was abolished by hepatic branch vagotomy, atropine, indomethacin and N(G)-nitro-L-arginine methyl ester, but not by 6-hydroxydopamine." | 3.72 | Protective effect of central thyrotropin-releasing hormone on carbon tetrachloride-induced acute hepatocellular necrosis in rats. ( Makino, I; Nakamura, K; Sato, Y; Terano, A; Yoneda, M, 2003) |
| " Hepatotoxic compounds such as CCl4, galactosamine and thioacetamide that cause hepatic necrosis and compounds such as hydrazine and ethionine that cause fatty liver all result in elevated urinary taurine levels in rats." | 3.69 | Changes in taurine as an indicator of hepatic dysfunction and biochemical perturbations. Studies in vivo and in vitro. ( Timbrell, JA; Waterfield, CJ, 1996) |
| "When carbon tetrachloride (CCl4) was administered to rats, a localized region of hepatic edema could be detected within 1 h by in vivo proton magnetic resonance imaging." | 3.69 | In vivo magnetic resonance imaging study of Kupffer cell involvement in CCl4-induced hepatotoxicity in rats. ( Janzen, EG; Reinke, LA; Towner, RA; Yamashiro, S, 1994) |
| "Endothelial cell damage causes massive hepatic necrosis as a result of fibrin deposition in the hepatic sinusoids." | 3.69 | Use of prostaglandin I2 analog in treatment of massive hepatic necrosis associated with endothelial cell injury and diffuse sinusoidal fibrin deposition. ( Arai, M; Fujiwara, K; Hirata, K; Masaki, N; Matsui, A; Mochida, S; Nagoshi, S; Ohno, A; Tomiya, T; Yamaoka, M, 1995) |
| "Administration of the radioprotective agent 2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721) at 3 or 6 hr after carbon tetrachloride (CCl4) administration significantly prevented the liver necrosis produced by the hepatotoxin at 24 hr." | 3.69 | Radioprotectors as late preventive agents against carbon tetrachloride induced liver necrosis: protection by 2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721). ( Castro, JA; de Castro, CR; Valles, EG, 1995) |
| "Fluphenazine (FP) treatment (50 mg/kg bw, ip in saline) 30 min before or 6 or 10 h after CCl4 administration (1 ml/kg ip in olive oil) significantly prevented the liver necrosis produced by the hepatotoxin at 24 h." | 3.69 | Late protective effects of the anticalmodulin drug fluphenazine on carbon tetrachloride-induced liver necrosis. ( Bernacchi, AS; Castro, GD; Castro, JA; de Ferreyra, EC; San Martin, MF, 1995) |
| "The therapeutic potency of 5,6,7,8-tetrahydroneopterin (NPH4) was investigated in ischemic paw edema, Adriamycin (ADR)-induced cardiotoxicity, and endotoxin [lipopolysaccharide (LPS)]- and carbon tetrachloride (CCl4)-induced hepatotoxicity in mice." | 3.68 | Protective effects of tetrahydroneopterin against free radical-induced injury. ( Icho, T; Kajiwara, Y; Kitabatake, K; Kojima, S; Kubota, K; Shinohara, N, 1993) |
| "Hepatic granulomas induced by a single or several subcutaneous injections of carbon tetrachloride (CCl4) in Balb/c mice were examined electronmicroscopically and immunocytochemically." | 3.68 | Granuloma formation in the liver of Balb/c mice intoxicated with carbon tetrachloride. ( Lukita-Atmadja, W; Sato, T; Wake, K, 1993) |
| "Liver necrosis was produced in rats by administering 3 doses of a mixture of carbon tetrachloride + olive oil, 2 ml/kg, ip." | 3.68 | Effect of aspartate and glutamate on carbon tetrachloride induced liver damage in rats. ( Garg, KN; Mehrotra, GC; Singh, J, 1990) |
| " Similar findings were obtained in rats with CCl4 liver damage or gentamicin nephrotoxicity, except that those rats hardly exhibited anemia because of a simultaneous occurrence of hemoconcentration." | 3.67 | The influence of single or repeated phlebotomy on the physiological condition of normal and diseased rats. ( Furuhama, K; Igarashi, K; Kato, M; Onodera, T; Suzuki, N, 1987) |
| " Centrilobular necrosis and marked elevation of serum glutamic-pyruvic transaminase (SGPT) and serum glutamic-oxaloacetic transaminase (SGOT) activities were induced by carbon tetrachloride (0." | 3.67 | Potentiation of carbon tetrachloride hepatotoxicity by hypoxia. ( Shibayama, Y, 1986) |
| "We examined the effect of liver damage induced by carbon tetrachloride on the incidence of hepatic metastasis in the Greene hamster melanoma." | 3.67 | An investigation into the association between liver damage and metastatic uveal melanoma. ( Albert, DM; Fournier, GA; Hatfield, RM; Pascal, SG; Saulenas, AM; Seddon, JM, 1985) |
| " The method was applied to patients with liver diseases and rheumatoid arthritis with and without treatment with antiinflammatory drugs and to rats after administration of indomethacin or carbon tetrachloride." | 3.66 | An improved method of determination of SH group concentration and reactivity in plasma of patients with various clinical disorders and in rats after administration of indomethacin or carbon tetrachloride. ( di Simplicio, P, 1983) |
| "Studies in the rat with hepatic necrosis induced by carbon tetrachloride showed that the abnormalities in one-stage coagulation tests and the increased catabolism of fibrinogen were similar to those found in man with acute viral or drug-induced hepatic necrosis." | 3.65 | Experimental hepatic necrosis: studies on coagulation abnormalities, plasma clearance, and organ distribution of 125I-labelled fibrinogen. ( Flute, PT; Pannell, G; Rake, MO; Shilkin, KB; Williams, R, 1973) |
| " Rats who had carbon tetrachloride-induced liver cirrhosis without pancreatic damage showed no increased hepatic storage iron." | 3.65 | The effect of pancreatectomy and other agents on iron absorption and storage in the rat. ( Bell, TK; Neill, DW; Sinniah, R, 1973) |
| "Melatonin is a powerful endogenous antioxidant produced by the pineal gland and a variety of other organs and many studies confirm its benefits against oxidative stress including lipid peroxidation, protein mutilation and molecular degeneration in various organs, including the liver." | 2.53 | Melatonin's role in preventing toxin-related and sepsis-mediated hepatic damage: A review. ( Alatorre-Jiménez, MA; Almeida-Souza, P; Cantín-Golet, A; Esteban-Zubero, E; García, JJ; López-Pingarrón, L; Reiter, RJ; Reyes-Gonzales, MC; Ruiz-Ruiz, FJ; Tan, DX, 2016) |
| " However, rats fed with CPS exhibited mitigation of CCl4-induced toxic effects on hematological parameters and hepatotoxicity." | 1.91 | Cakes fortified with papaya seeds effectively protects against CCl4-induced immunotoxicity. ( Abdel-Hameed, SM; Gazwi, HSS; Soltan, OIA, 2023) |
| "Liver fibrosis is a prevalent liver disease that requires rapid and effective treatment prior to its progression to cirrhosis and liver damage." | 1.72 | Oral supplementation of policosanol alleviates carbon tetrachloride-induced liver fibrosis in rats. ( Albogami, SM; Alotaibi, SS; Batiha, GE; Elewa, YHA; Makled, S; Mostafa-Hedeab, G; Yassin, F; Zein, N, 2022) |
| "TGF-β signaling links HSC activation to liver fibrosis and tumorigenesis." | 1.62 | Perivenous Stellate Cells Are the Main Source of Myofibroblasts and Cancer-Associated Fibroblasts Formed After Chronic Liver Injuries. ( Ge, G; Lin, M; Peng, YJ; Ren, Z; Shang, G; Tang, XT; Wang, SS; Yin, X; Yuan, J; Zhou, BO, 2021) |
| "The knowledge of pharmacokinetic and pharmacodynamic properties of antiepileptic drugs is helpful in optimizing drug therapy for epilepsy." | 1.46 | Evaluation of Brain Pharmacokinetic and Neuropharmacodynamic Attributes of an Antiepileptic Drug, Lacosamide, in Hepatic and Renal Impairment: Preclinical Evidence. ( Kumar, B; Medhi, B; Modi, M; Saikia, B, 2017) |
| " The LD50 of MSE was more than 5000 mg/kg." | 1.40 | Hepatoprotective and antioxidant activity of Melaleuca styphelioides on carbon tetrachloride-induced hepatotoxicity in mice. ( Al-Sayed, E; El-Lakkany, NM; Hammam, OA; Sabra, AN; Seif El-Din, SH, 2014) |
| " Also, there might be potential interactions between SLE or DDB and co-administered medicines and it is necessary to adjust the dosage of co-administrated medicines in clinical medication of liver disease." | 1.40 | Reversing effects of lignans on CCl4-induced hepatic CYP450 down regulation by attenuating oxidative stress. ( Guo, C; Hao, H; Kang, A; Wang, G; Wang, H; Xie, Y, 2014) |
| " However, its poor bioavailability limits its use in therapeutics." | 1.40 | Attenuation of carbon tetrachloride-induced hepatic injury with curcumin-loaded solid lipid nanoparticles. ( Kakkar, V; Kaur, IP; Khullar, N; Singh, N, 2014) |
| " Some drugs in this formula have toxicities that might result in some adverse effects of DHZCP." | 1.38 | Evaluation of the liver protection and toxicity of Da-Huang-Zhe-Chong pill in rats. ( Jia, L; Kong, WJ; Ren, HL; Wang, JB; Xiao, XH; Xing, XY; Zhang, P; Zhao, YL; Zhong, YW, 2012) |
| "Its ethyl acetate extract has shown potent in vitro antioxidant activity and found to contain 7." | 1.36 | Antioxidant and hepatoprotective effect of the ethyl acetate extract of Enicostemma axillare (Lam). Raynal against CCL4-induced liver injury in rats. ( Badami, S; Jaishree, V; Krishnamurthy, PT, 2010) |
| " Toxicity, pharmacokinetics and clinical bioavailability of resveratrol are also reviewed in this article." | 1.36 | Resveratrol and liver disease: from bench to bedside and community. ( Bishayee, A; Darvesh, AS; McGory, R; Politis, T, 2010) |
| "Carbon tetrachloride (CCl₄) treatment to rats has been more susceptible to peroxidative damage through production of reactive metabolites, namely trichloromethyl-free radicals (CCl₃• and/or CCl₃• OO•) as measured by thiobarbituric acid reactive species." | 1.35 | Effects of embelin on lipid peroxidation and free radical scavenging activity against liver damage in rats. ( Gupta, RS; Singh, D; Singh, P; Singh, R, 2009) |
| "The pharmacokinetic profile of ceftriaxone was studied in female healthy goats, induced hepatopathic and nephropathic goats after a single intravenous dose at 50 mg kg(-1)." | 1.35 | Pharmacokinetics of ceftriaxone in carbontetrachloride-induced hepatopathic and uranyl nitrate-induced nephropathic goats following single dose intravenous administration. ( Chakraborty, AK; Das, SK; Mandal, TK; Sar, TK, 2008) |
| "Carbon tetrachloride (CCl4) is a xenobiotic used extensively to induce oxidative stress and is one of the most widely used hepatic toxins for experimental induction of liver fibrosis in the laboratory." | 1.35 | Effects of silymarin on the resolution of liver fibrosis induced by carbon tetrachloride in rats. ( Ho, PC; Hsieh, YS; Huang, CY; Liu, JY; Liu, YC; Shyu, JC; Tsai, CC; Tsai, JH; Wu, TT, 2008) |
| "Several in vitro studies have demonstrated the ability of pure trans-resveratrol (t-Res) to act as an anti-oxidant, but the scientific literature is lacking in in vivo studies dealing with dietary t-Res bioavailability in oxidative stress models." | 1.35 | Dietary trans-resveratrol bioavailability and effect on CCl4-induced liver lipid peroxidation. ( Caporaso, N; Fogliano, V; Milani, S; Morisco, F; Ottanelli, B; Vitaglione, P, 2009) |
| "Fibrosis was quantified by densitometry on Sirius red-stained histological sections." | 1.34 | Assessment of diffusion-weighted MR imaging in liver fibrosis. ( Abarca-Quinones, J; Annet, L; Leclercq, I; Moulin, P; Peeters, F; Van Beers, BE, 2007) |
| "Co-treatment with salvianolic acid A (20 mg/kg, intraperitoneally), a water-soluble extract from a Chinese traditional drug, Radix Salvia miltiorrhiza, significantly decreased CCl(4)-induced hepatotoxicity." | 1.34 | Effects of salvianolic acid a on oxidative stress and liver injury induced by carbon tetrachloride in rats. ( Liu, Y; Ren, F; Tan, YF; Wen, T; Wu, H; Wu, ZM, 2007) |
| "Bakuchiol treatment stimulated the activation of extracellular signal-regulated kinase 1/2 (ERK), c-Jun NH2-terminal protein kinase (JNK), and p38 mitogen-activated protein kinases (MAPK) in vitro." | 1.34 | Bakuchiol-induced caspase-3-dependent apoptosis occurs through c-Jun NH2-terminal kinase-mediated mitochondrial translocation of Bax in rat liver myofibroblasts. ( Kim, YC; Park, EJ; Sohn, DH; Zhao, YZ, 2007) |
| "To investigate the protective effect of Yigan Fuzheng Paidu Capsules (YC) combined with medical ozone against hepatic injury in dogs induced by hepatotoxic drug." | 1.34 | [Protective effect of Yigan Fuzheng Paidu capsules combined with ozone on CCl4-induced acute hepatic injury in dogs]. ( Chen, PC; Guo, YB; Hua, HY; Huo, D; Li, LJ; Wang, C; Yang, YG; Zhang, HS; Zhang, ZL, 2007) |
| "Genistein has anti-inflammatory and antinecrotic effects on experimental liver damage caused by CCl4." | 1.34 | Protective role of genistein in acute liver damage induced by carbon tetrachloride. ( Akdemir, F; Bahcecioglu, IH; Dagli, AF; Kuzu, N; Metin, K; Orhan, C; Ozercan, IH; Sahin, K; Yalniz, M, 2007) |
| "Pretreatment with kahweol and cafestol prior to the administration of CCl(4) significantly prevented the increase in the serum levels of hepatic enzyme markers (alanine aminotransferase and aspartate aminotransferase) and reduced oxidative stress, such as reduced glutathione content and lipid peroxidation, in the liver in a dose-dependent manner." | 1.34 | Hepatoprotective and antioxidant effects of the coffee diterpenes kahweol and cafestol on carbon tetrachloride-induced liver damage in mice. ( Choi, JH; Jeong, HG; Lee, KJ, 2007) |
| "Gabexate mesilate treatment significantly decreased the elevation of serum transaminase levels and improved liver histology 24 h after the administration of CCl4 (0." | 1.33 | Gabexate mesilate, a synthetic protease inhibitor, attenuates carbon tetrachloride-induced liver injury in rats. ( Goto, T; Kataoka, E; Lin, JG; Mikami, K; Miura, K; Ohshima, S; Segawa, D; Shibuya, T; Watanabe, D; Watanabe, S; Yoneyama, K, 2005) |
| " Aiming at improving its poor bioavailability from oral products, silymarin hybrid liposomes are introduced in this work for buccal administration after investigating their stability and in vivo hepatoprotective efficiency." | 1.33 | Evaluation of hybrid liposomes-encapsulated silymarin regarding physical stability and in vivo performance. ( Afifi, NN; El-Samaligy, MS; Mahmoud, EA, 2006) |
| "Carbon tetrachloride (CCl(4)) treatment of rats causes lipid peroxidation of cell membranes and produces massive hepatic injury." | 1.33 | Highly liver-specific heme oxygenase-1 induction by interleukin-11 prevents carbon tetrachloride-induced hepatotoxicity. ( Akagi, R; Katayama, H; Kawakami, T; Morita, K; Nakahira, K; Sassa, S; Shimizu, H; Takahashi, T; Takeuchi, M; Yokoyama, M, 2006) |
| "Oleanolic acid is a naturally derived triterpene used clinically in the treatment of hepatitis in China, but its poor solubility often leads to poor bioavailability." | 1.33 | Oleanolic acid nanosuspensions: preparation, in-vitro characterization and enhanced hepatoprotective effect. ( Chen, Y; Liu, J; Xu, H; Yang, X; Zhao, X, 2005) |
| " PGE2 administration started 3 h after the additional dosing of CCl4 and PGE2 effect on hepatorenal function was examined on days 1, 2, 3, and 7." | 1.33 | PGE2 alleviates kidney and liver damage, decreases plasma renin activity and acute phase response in cirrhotic rats with acute liver damage. ( Armendáriz-Borunda, J; Covarrubias, A; Cruz, C; Estanes, A; Islas-Carbajal, MC; Panduro, A; Pedraza-Chaverrí, J; Rincón-Sánchez, AR; Rivas-Estilla, AM, 2005) |
| "Carbon tetrachloride was used as the oxidative stress inducer." | 1.32 | Effects of chicken extract on antioxidative status and liver protection under oxidative stress. ( Lin, SH; Peng, HC, 2004) |
| "Portal hypertension was successfully induced in 15 dogs." | 1.32 | [Morphology of portal hypertension at the early stage of liver damage induced by CCl4: an experimental study with dogs]. ( Wei, YW; Xue, DB; Zhang, RP; Zhang, WH, 2004) |
| " The results showed that the inhibitory effect of DMF and its crude triterpenoids on lipid peroxidation occurred in a dose-response manner in an AAPH/linoleic acid system." | 1.32 | Protective effects of fermented filtrate from Antrodia camphorata in submerged culture against CCl4-induced hepatic toxicity in rats. ( Song, TY; Yen, GC, 2003) |
| "Metallothionein and zinc have been implicated in cellular defense against a number of cytotoxic agents." | 1.31 | Metallothionein expression protects against carbon tetrachloride-induced hepatotoxicity, but overexpression and dietary zinc supplementation provide no further protection in metallothionein transgenic and knockout mice. ( Cousins, RJ; Davis, SR; Samuelson, DA, 2001) |
| "(Cucurbitaceae) were tested for their hepatoprotective activity against CCl(4) induced hepatotoxicity in albino rats." | 1.31 | Hepatoprotective activity of Luffa echinata fruits. ( Ahmed, B; Alam, T; Khan, SA, 2001) |
| "Carbon tetrachloride was injected intraperitoneally into mice deficient in plasminogen, fibrinogen, or both, and to normal littermates, followed by determination of the phenotype of HSCs, matrix deposition, and apoptosis." | 1.31 | Plasminogen deficiency results in poor clearance of non-fibrin matrix and persistent activation of hepatic stellate cells after an acute injury. ( Bezerra, JA; Degen, JL; Kelley-Loughnane, N; Melin-Aldana, H; Ng, VL; Sabla, GE, 2001) |
| "Liver-necrosis was observed in CCl(4)-injected rats without pretreatment of flaxseed extract." | 1.31 | Protective effect of a lignan-containing flaxseed extract against CCl(4)-induced hepatic injury. ( Arikawa, J; Endoh, D; Hayashi, M; Kon, Y; Okui, T; Ozawa, S; Yamato, O, 2002) |
| " The results of these studies demonstrated that CS-mediated protection is not selective for a particular species, organ system or toxic chemical." | 1.30 | Cholesteryl hemisuccinate treatment protects rodents from the toxic effects of acetaminophen, adriamycin, carbon tetrachloride, chloroform and galactosamine. ( Fariss, MW; Lippman, HR; Mumaw, VR; Ray, SD, 1997) |
| " No toxicologically significant differences in pharmacokinetic parameters as a function of Emulphor concentration were found." | 1.30 | Effect of Emulphor, an emulsifier, on the pharmacokinetics and hepatotoxicity of oral carbon tetrachloride in the rat. ( Bruckner, JV; Sanzgiri, UY, 1997) |
| "Astilbine was capable to restore lipoperoxides and tissue prostanoids to basal values." | 1.30 | Prostanoids and free radicals in Cl4C-induced hepatotoxicity in rats: effect of astilbin. ( Bioque, G; Closa, D; Gelpí, E; Hotter, G; León, OS; Rósello-Catafau, J; Torres, M, 1997) |
| "The aim of this work was to determine if the inhibition or stimulation of NO synthesis modulates liver damage induced by the chronic administration of CCl4." | 1.30 | Nitric oxide protection of rat liver from lipid peroxidation, collagen accumulation, and liver damage induced by carbon tetrachloride. ( Muriel, P, 1998) |
| "Carbon tetrachloride-injected rats were given liquid diets with and without betaine for 7 d." | 1.30 | Betaine reduces hepatic lipidosis induced by carbon tetrachloride in Sprague-Dawley rats. ( Barak, AJ; Beckenhauer, HC; Junnila, M; Rahko, T, 1998) |
| "Pretreatment with oleanolic acid prior to the administration of carbon tetrachloride significantly prevented the increase in serum alanine aminotransferase and lactate dehydrogenase activity and liver lipid peroxidation in a dose-dependent manner." | 1.30 | Inhibition of cytochrome P450 2E1 expression by oleanolic acid: hepatoprotective effects against carbon tetrachloride-induced hepatic injury. ( Jeong, HG, 1999) |
| " From these experiments, we conclude that retinol pretreatment decreases the severity of 2-nitronaphthalene and paraquat-induced pulmonary toxicity, apparently by inhibiting the inflammatory responses associated with the progression of toxic injury." | 1.29 | Modulation of chemical-induced lung and liver toxicity by all-trans-retinol in the male Sprague-Dawley rat. ( Sauer, JM; Sipes, IG, 1995) |
| "The present study was designed to evaluate the effects of dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate (PMC) in combination with garlic oil against chemical-induced hepatic injury in rats and mice." | 1.29 | Enhanced effectiveness of dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate in combination with garlic oil against experimental hepatic injury in rats and mice. ( Chung, HC; Hong, SY; Jung, KH; Kim, SG; Nam, SY, 1995) |
| "Quinacrine (QUIN) is a well known inhibitor of PLA2." | 1.29 | Late preventive effects of quinacrine on carbon tetrachloride induced liver necrosis. ( Castro, JA; de Toranzo, EG; González Padrón, A, 1993) |
| " Light microscopic examination of sections of the liver taken 5 weeks after dosing of CCl4 showed hydropic degeneration of hepatocytes around the central veins and lipid vacuolation in mid-zonal and some periportal hepatocytes." | 1.29 | Abnormal expressions of hepatocellular proteins and extracellular matrix in CCL4-induced liver injury in rats. ( Chen, L; Yang, X; Zhong, X; Zhou, J, 1996) |
| "Colchicine was administered 2 h prior to CCl4 or corn oil injection." | 1.29 | Effect of antimitotic agent colchicine on carbon tetrachloride toxicity. ( Mehendale, HM; Rao, VC, 1993) |
| " The pharmacokinetic analysis of these data showed that the decreased total plasma clearance of ICG in GAL and CCl4 rats results from both lowered influx across the sinusoidal plasma membrane of hepatocytes and the decreased hepatic plasma flow." | 1.29 | Pharmacokinetics of indocyanine green in rats with experimentally induced hepatic diseases. ( Kimura, T; Kurosaki, Y; Nakayama, S; Nakayama, T; Yamao, T, 1993) |
| " In the initial 3-week dose-response study, as the daily dose of VA increased so did the degree of potentiation of CCl4 hepatotoxicity." | 1.29 | Characterization of vitamin A potentiation of carbon tetrachloride-induced liver injury. ( Earnest, DL; elSisi, AE; Hall, P; Sim, WL; Sipes, IG, 1993) |
| " Rats or mice were dosed with VA (retinol) at 75 mg/kg/day, po, for 7 days." | 1.29 | Vitamin A modulation of xenobiotic-induced hepatotoxicity in rodents. ( Hill, DA; Hooser, SB; Mobley, SA; Rosengren, RJ; Sipes, IG, 1994) |
| "Hyperbilirubinemia was observed early in ponies of the ligated group; most of the bilirubin was of the conjugated type." | 1.28 | Serum lipid and lipoprotein changes in ponies with experimentally induced liver disease. ( Bauer, JE; Campbell, M; McMurphy, R; Meyer, DJ, 1990) |
| "142) were found to protect mice against the hepatotoxicity of paracetamol, which is due to cytochrome P-450 dependent formation of toxic metabolites and radicals." | 1.28 | In vivo effects of immunostimulating lipopeptides on mouse liver microsomal cytochromes P-450 and on paracetamol-induced toxicity. ( Delaforge, M; Jaouen, M; Jollès, P; Mansuy, D; Migliore-Samour, D, 1989) |
| " In retrograde perfusion under low oxygen supply with Ca2+, CCl4 produced essentially the same toxic manifestations as those observed in the anterograde perfusion." | 1.28 | Effects of oxygen deficiency and calcium omission on carbon tetrachloride hepatotoxicity in isolated perfused livers from phenobarbital-pretreated rats. ( Masuda, Y; Nakamura, Y, 1990) |
| " Animals pretreated with this hepatotoxic agent showed a significant prolongation in the half-life of diazepam in plasma that is due more to an increase in volume of distribution rather than to a decrease in clearance." | 1.28 | Pharmacokinetics of diazepam in the rat: influence of a carbon tetrachloride-induced hepatic injury. ( Díaz-García, JM; Fos-Galve, D; Oliver-Botana, J, 1992) |
| " The peak elevation in urinary taurine occurred within the first 48 h after dosing but there was still significant taurinuria 72 and 96 h after the intermediate dose (1 ml." | 1.28 | Taurine, a possible urinary marker of liver damage: a study of taurine excretion in carbon tetrachloride-treated rats. ( Scales, MD; Timbrell, JA; Turton, JA; Waterfield, CJ, 1991) |
| " Liver samples were collected from these mice 5 days before (by biopsy) and 18 days after dosing with CCl4 (1 ml/kg, i." | 1.28 | Evidence of clonal proliferation of hepatocytes after carbon-tetrachloride-induced hepatic injury in PGK-1 mosaic mice. ( Kamiyama, S; Koizumi, A; Tsukada, M; Wada, Y, 1990) |
| " After dosing 100 microliter CCl4/kg, the response of OCT activity was 10- and 20-times higher than that of GOT and GPT, respectively." | 1.27 | Comparative study on the sensitivity of several serum enzymes in detecting hepatic damage in rats. ( Baumann, M; Berauer, M, 1985) |
| "Post-treatment with methoxsalen must be given early and is only partially effective in mice." | 1.27 | The drug methoxsalen, a suicide substrate for cytochrome P-450, decreases the metabolic activation, and prevents the hepatotoxicity, of carbon tetrachloride in mice. ( Amouyal, G; Carrion-Pavlov, Y; Degott, C; Descatoire, V; Geneve, J; Labbe, G; Larrey, D; Letteron, P; Pessayre, D; Tinel, M, 1987) |
| "Sodium propionate (3 mmol/kg) was injected IV into 6 healthy sheep before and after they were given carbon tetrachloride (20% CCl4 in mineral oil; 0." | 1.27 | Propionate loading test for liver function during experimental liver necrosis in sheep. ( Bruss, ML; Gröhn, Y; Lindberg, LA, 1985) |
| "Carbon tetrachloride was injected s." | 1.27 | Strain differences in mice in carbon tetrachloride-induced liver injury. ( Bhathal, PS; Mackay, IR; Rose, NR; Whittingham, S, 1983) |
| " These permit the elaboration of dose-response lines for the substances in question, the calculation of median effective doses and the statistical analysis of differences in liver-damaging potency." | 1.26 | Quantitative aspects in the assessment of liver injury. ( Plaa, GL, 1976) |
| " The result suggests that the acquired resistance to a toxic dose of furylfuramide is due to the acceleration of detoxication of the drug." | 1.26 | Development of resistance to hepatotoxic effect of furylfuramide by pretreatment with its subnecrotic doses and carbon tetrachloride. ( Horiuchi, T; Ohtsubo, K; Saito, M, 1978) |
| "The tumour growth, dehydration and burning of rats as well as sleep deprivation, overheating, lanthanum and ruthenium red have been shown to cause changes in the activity of some enzyme-systems located in endoplasmic reticulum." | 1.26 | Effect of different factors modifying the activity of some enzyme systems of the endoplastic reticulum on the sensitivity of cell organelles against the damaging action of chemical agents. I: Interrelations between the activity of some enzyme systems loca ( Geneva, L; Georgiev, G; Popov, CS; Yantchev, I, 1976) |
| " Prior dosing with phenobarbitone augments CCl4 toxicity only in the adult and the newborn but the foetus continues to be resistant." | 1.25 | Diverse mechanisms of hepatocellular injuries due to chemicals: evidence in rats administered carbon tetrachloride or dimethylnitrosamine. ( Chopra, P; Das, PK; Dhar, A; Nayak, NC, 1975) |
| "In rats the effect of a chronic administration of CCl4 on the excretion and disstribution of 64Cu, 65Zn, and 203Hg was investigated." | 1.25 | Biliary excretion of 64Cu, 65Zn and 203Hg in the rat with liver injury induced by CCl4. ( Cikrt, M; Holusa, R; Tichý, M, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 258 (37.66) | 18.7374 |
| 1990's | 136 (19.85) | 18.2507 |
| 2000's | 205 (29.93) | 29.6817 |
| 2010's | 63 (9.20) | 24.3611 |
| 2020's | 23 (3.36) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, S | 1 |
| Kong, F | 1 |
| Sun, Z | 1 |
| Xi, Y | 1 |
| Qi, F | 2 |
| Sun, J | 1 |
| Hu, D | 1 |
| Huang, S | 2 |
| Ding, Y | 1 |
| Zhao, X | 2 |
| Zhang, W | 1 |
| Chen, H | 1 |
| Wang, J | 4 |
| Zhang, RZ | 1 |
| Liu, Y | 4 |
| Li, M | 1 |
| Huang, YL | 1 |
| Song, ZH | 1 |
| Zein, N | 1 |
| Yassin, F | 1 |
| Makled, S | 1 |
| Alotaibi, SS | 1 |
| Albogami, SM | 1 |
| Mostafa-Hedeab, G | 1 |
| Batiha, GE | 1 |
| Elewa, YHA | 1 |
| Yin, G | 2 |
| Zeng, W | 1 |
| Li, R | 1 |
| Zeng, M | 1 |
| Chen, R | 1 |
| Jiang, R | 1 |
| Wang, Y | 5 |
| Acosta-Cota, SJ | 1 |
| Castillo-Romero, DJ | 1 |
| Montes-Ávila, J | 1 |
| Delgado-Vargas, F | 1 |
| Báez-Flores, ME | 1 |
| Noguera-Corona, E | 1 |
| Osuna-Martínez, U | 1 |
| Nanda, I | 1 |
| Schröder, SK | 1 |
| Steinlein, C | 1 |
| Haaf, T | 1 |
| Buhl, EM | 1 |
| Grimm, DG | 1 |
| Weiskirchen, R | 2 |
| Hassan, R | 1 |
| González, D | 1 |
| Hobloss, Z | 1 |
| Brackhagen, L | 1 |
| Myllys, M | 1 |
| Friebel, A | 1 |
| Seddek, AL | 1 |
| Marchan, R | 1 |
| Cramer, B | 1 |
| Humpf, HU | 1 |
| Hoehme, S | 1 |
| Degen, GH | 1 |
| Hengstler, JG | 1 |
| Ghallab, A | 1 |
| Yang, AT | 2 |
| Kim, YO | 2 |
| Yan, XZ | 2 |
| Abe, H | 2 |
| Aslam, M | 2 |
| Park, KS | 2 |
| Zhao, XY | 2 |
| Jia, JD | 2 |
| Klein, T | 2 |
| You, H | 2 |
| Schuppan, D | 4 |
| Batool, R | 2 |
| Khan, MR | 3 |
| Ijaz, MU | 1 |
| Naz, I | 2 |
| Batool, A | 1 |
| Ali, S | 2 |
| Zahra, Z | 1 |
| Gul, S | 1 |
| Uddin, MN | 1 |
| Kazi, M | 1 |
| Khan, R | 1 |
| Wang, M | 1 |
| Zhang, L | 2 |
| Yue, H | 1 |
| Cai, W | 1 |
| Yin, H | 1 |
| Tian, Y | 1 |
| Dong, P | 1 |
| Çakır, S | 1 |
| Geervliet, E | 1 |
| Terstappen, LWMM | 1 |
| Bansal, R | 1 |
| Averyanova, EV | 1 |
| Shkolnikova, MN | 1 |
| Chugunova, OV | 1 |
| Mazko, ON | 1 |
| Gazwi, HSS | 1 |
| Soltan, OIA | 1 |
| Abdel-Hameed, SM | 1 |
| Hu, K | 1 |
| Xu, J | 2 |
| Fan, K | 1 |
| Zhou, D | 1 |
| Li, L | 3 |
| Tang, L | 1 |
| Peng, X | 1 |
| Luo, L | 1 |
| Zhang, G | 1 |
| Mao, L | 1 |
| Wang, P | 2 |
| Xi, C | 1 |
| Shi, G | 1 |
| Leavenworth, JW | 1 |
| You, S | 1 |
| Cui, AM | 1 |
| Hashmi, SF | 1 |
| Zhang, X | 3 |
| Nadolny, C | 1 |
| Chen, Y | 5 |
| Chen, Q | 1 |
| Bush, X | 1 |
| Hurd, Z | 1 |
| Ali, W | 1 |
| Qin, G | 1 |
| Deng, R | 1 |
| Tang, G | 1 |
| Seume, N | 1 |
| Häger, C | 1 |
| Kumstel, S | 1 |
| Abshagen, K | 1 |
| Bleich, A | 1 |
| Vollmar, B | 1 |
| Talbot, SR | 1 |
| Zechner, D | 1 |
| Wang, SS | 1 |
| Tang, XT | 1 |
| Lin, M | 1 |
| Yuan, J | 1 |
| Peng, YJ | 1 |
| Yin, X | 1 |
| Shang, G | 1 |
| Ge, G | 1 |
| Ren, Z | 3 |
| Zhou, BO | 1 |
| Dar, MA | 1 |
| Mir, PA | 1 |
| Masoodi, MH | 1 |
| Alqahtani, AS | 1 |
| Siddiqui, NA | 1 |
| Ahmad, B | 3 |
| Yu, X | 1 |
| Huang, L | 2 |
| You, C | 1 |
| Lee, J | 1 |
| Kim, SR | 2 |
| Lee, C | 1 |
| Jun, YI | 1 |
| Bae, S | 1 |
| Yoon, YJ | 1 |
| Kim, OY | 1 |
| Gho, YS | 1 |
| Kumar, B | 1 |
| Modi, M | 1 |
| Saikia, B | 1 |
| Medhi, B | 1 |
| Li, X | 2 |
| Yao, QY | 1 |
| Liu, HC | 1 |
| Jin, QW | 1 |
| Xu, BL | 1 |
| Zhang, SC | 1 |
| Tu, CT | 1 |
| Spirlandeli, AL | 1 |
| Dick-de-Paula, I | 1 |
| Zamarioli, A | 1 |
| Jorgetti, V | 1 |
| Ramalho, LNZ | 1 |
| Nogueira-Barbosa, MH | 1 |
| Volpon, JB | 1 |
| Jordão, AA | 1 |
| Cunha, FQ | 1 |
| Fukada, SY | 1 |
| de Paula, FJA | 1 |
| Athwal, VS | 1 |
| Pritchett, J | 1 |
| Llewellyn, J | 1 |
| Martin, K | 1 |
| Camacho, E | 1 |
| Raza, SM | 1 |
| Phythian-Adams, A | 1 |
| Birchall, LJ | 1 |
| Mullan, AF | 1 |
| Su, K | 1 |
| Pearmain, L | 1 |
| Dolman, G | 1 |
| Zaitoun, AM | 1 |
| Friedman, SL | 1 |
| MacDonald, A | 1 |
| Irving, WL | 1 |
| Guha, IN | 1 |
| Hanley, NA | 1 |
| Piper Hanley, K | 1 |
| Xu, TB | 1 |
| Luo, XD | 1 |
| Lin, H | 1 |
| Tang, X | 2 |
| Olatunji, OJ | 1 |
| Zhou, Y | 2 |
| Hou, X | 1 |
| Wu, YJ | 1 |
| Wu, YC | 1 |
| Chen, IF | 1 |
| Wu, YL | 1 |
| Chuang, CW | 1 |
| Huang, HH | 1 |
| Kuo, SM | 1 |
| Nwidu, LL | 1 |
| Oboma, YI | 1 |
| Elmorsy, E | 1 |
| Carter, WG | 1 |
| Rashid Khan, M | 1 |
| Ahmed Zai, J | 1 |
| Maryam, S | 1 |
| Bibi, S | 1 |
| Kim, KY | 1 |
| Lee, SG | 2 |
| Baek, SY | 1 |
| Lee, EH | 1 |
| Jang, EJ | 1 |
| Lee, JH | 2 |
| Ahn, SC | 1 |
| Chang, JH | 1 |
| Oh, TW | 1 |
| Kim, SH | 2 |
| Ma, JY | 1 |
| Kim, SC | 1 |
| Park, KI | 1 |
| Kim, YW | 1 |
| Tung, NT | 1 |
| Tran, CS | 1 |
| Nguyen, HA | 1 |
| Nguyen, TD | 1 |
| Chi, SC | 1 |
| Pham, DV | 1 |
| Bui, QD | 1 |
| Ho, XH | 1 |
| Ko, J | 1 |
| Yeh, WJ | 1 |
| Huang, WC | 1 |
| Yang, HY | 2 |
| Yang, X | 3 |
| Yang, S | 1 |
| Guo, Y | 1 |
| Jiao, Y | 1 |
| Zhao, Y | 3 |
| Huan, SK | 1 |
| Wang, KT | 1 |
| Lee, CJ | 1 |
| Sung, CH | 1 |
| Chien, TY | 2 |
| Wang, CC | 2 |
| Hu, J | 1 |
| Zhao, J | 1 |
| Chen, W | 2 |
| Lin, S | 1 |
| Zhang, J | 2 |
| Hong, Z | 1 |
| Duncan, MB | 1 |
| Yang, C | 1 |
| Tanjore, H | 1 |
| Boyle, PM | 1 |
| Keskin, D | 1 |
| Sugimoto, H | 1 |
| Zeisberg, M | 1 |
| Olsen, BR | 1 |
| Kalluri, R | 1 |
| Kubota, N | 1 |
| Kado, S | 1 |
| Kano, M | 1 |
| Masuoka, N | 1 |
| Nagata, Y | 1 |
| Kobayashi, T | 2 |
| Miyazaki, K | 1 |
| Ishikawa, F | 1 |
| Yeh, YH | 1 |
| Hsieh, YL | 1 |
| Lee, YT | 1 |
| Shah, NA | 2 |
| Noureen, F | 1 |
| Rashid, U | 2 |
| Khan, RA | 2 |
| Singh, N | 1 |
| Khullar, N | 1 |
| Kakkar, V | 1 |
| Kaur, IP | 1 |
| Xie, Y | 1 |
| Hao, H | 1 |
| Wang, H | 1 |
| Guo, C | 1 |
| Kang, A | 1 |
| Wang, G | 1 |
| Atasever, A | 1 |
| Yaman, D | 1 |
| Abdelaziz, DH | 1 |
| Ali, SA | 1 |
| Kumar, P | 1 |
| Ranawade, AV | 1 |
| Kumar, NG | 1 |
| Al-Sayed, E | 1 |
| El-Lakkany, NM | 1 |
| Seif El-Din, SH | 1 |
| Sabra, AN | 1 |
| Hammam, OA | 1 |
| Ebeid, HM | 1 |
| Gibriel, AA | 1 |
| Al-Sayed, HM | 1 |
| Elbehairy, SA | 1 |
| Motawe, EH | 1 |
| Kober, H | 1 |
| Tatsch, E | 1 |
| Torbitz, VD | 1 |
| Cargnin, LP | 1 |
| Sangoi, MB | 1 |
| Bochi, GV | 1 |
| da Silva, AR | 1 |
| Barbisan, F | 1 |
| Ribeiro, EE | 1 |
| da Cruz, IB | 1 |
| Moresco, RN | 1 |
| Chan, KW | 1 |
| Ho, WS | 1 |
| Wilson, CL | 1 |
| Murphy, LB | 1 |
| Leslie, J | 1 |
| Kendrick, S | 1 |
| French, J | 1 |
| Fox, CR | 1 |
| Sheerin, NS | 1 |
| Fisher, A | 1 |
| Robinson, JH | 1 |
| Tiniakos, DG | 1 |
| Gray, DA | 1 |
| Oakley, F | 1 |
| Mann, DA | 1 |
| Bak, J | 1 |
| Je, NK | 1 |
| Chung, HY | 1 |
| Yokozawa, T | 1 |
| Yoon, S | 1 |
| Moon, JO | 1 |
| Esteban-Zubero, E | 1 |
| Alatorre-Jiménez, MA | 1 |
| López-Pingarrón, L | 1 |
| Reyes-Gonzales, MC | 1 |
| Almeida-Souza, P | 1 |
| Cantín-Golet, A | 1 |
| Ruiz-Ruiz, FJ | 1 |
| Tan, DX | 1 |
| García, JJ | 1 |
| Reiter, RJ | 1 |
| Zou, J | 1 |
| Ye, L | 2 |
| Yao, S | 1 |
| Abdel-Hamid, NM | 1 |
| Wahid, A | 1 |
| Mohamed, EM | 1 |
| Abdel-Aziz, MA | 1 |
| Mohafez, OM | 1 |
| Bakar, S | 1 |
| Kopec, AK | 1 |
| Joshi, N | 1 |
| Luyendyk, JP | 1 |
| Xie, J | 1 |
| Yang, L | 4 |
| Tian, L | 1 |
| Li, W | 2 |
| Kojima-Yuasa, A | 1 |
| Goto, M | 1 |
| Yoshikawa, E | 1 |
| Morita, Y | 1 |
| Sekiguchi, H | 1 |
| Sutoh, K | 1 |
| Usumi, K | 1 |
| Matsui-Yuasa, I | 1 |
| Shi, H | 2 |
| Han, W | 2 |
| Ren, F | 2 |
| Chen, D | 1 |
| Duan, Z | 1 |
| Takahara, T | 2 |
| Xue, F | 2 |
| Mazzone, M | 1 |
| Yata, Y | 2 |
| Nonome, K | 1 |
| Kanayama, M | 1 |
| Kawai, K | 1 |
| Pisacane, AM | 1 |
| Takahara, S | 2 |
| Li, XK | 1 |
| Comoglio, PM | 1 |
| Sugiyama, T | 1 |
| Michieli, P | 1 |
| Wu, SJ | 1 |
| Lin, YH | 3 |
| Chu, CC | 1 |
| Tsai, YH | 1 |
| Chao, JC | 1 |
| Kim, HY | 1 |
| Kim, JH | 3 |
| Lee, SA | 1 |
| Chang, HE | 1 |
| Park, MH | 1 |
| Hwang, SJ | 1 |
| Lee, JY | 1 |
| Mok, C | 1 |
| Hong, SG | 1 |
| Shan, W | 1 |
| Palkar, PS | 1 |
| Murray, IA | 1 |
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| Chen, YL | 1 |
| Yang, SC | 1 |
| Huang, GC | 1 |
| Tsi, D | 1 |
| Huang, CC | 3 |
| Chen, JR | 1 |
| Li, JS | 1 |
| Cuciureanu, M | 1 |
| Căruntu, ID | 1 |
| Păduraru, O | 1 |
| Stoica, B | 1 |
| Jerca, L | 1 |
| Crauciuc, E | 1 |
| Nechifor, M | 1 |
| Jodynis-Liebert, J | 2 |
| Adamska, T | 2 |
| Ewertowska, M | 2 |
| Bylka, W | 2 |
| Matławska, I | 1 |
| Mamiya, T | 1 |
| Katsuoka, F | 1 |
| Hirayama, A | 1 |
| Nakajima, O | 1 |
| Kobayashi, A | 1 |
| Maher, JM | 1 |
| Matsui, H | 2 |
| Hyodo, I | 1 |
| Yamamoto, M | 1 |
| Hosoya, T | 1 |
| Patrick-Iwuanyanwu, KC | 1 |
| Wegwu, MO | 1 |
| Ayalogu, EO | 1 |
| Kim, HH | 1 |
| Ku, SK | 2 |
| Ferré, N | 2 |
| Martínez-Clemente, M | 1 |
| López-Parra, M | 4 |
| González-Périz, A | 3 |
| Horrillo, R | 2 |
| Planagumà, A | 4 |
| Camps, J | 1 |
| Joven, J | 1 |
| Tres, A | 1 |
| Guardiola, F | 1 |
| Bataller, R | 1 |
| Arroyo, V | 4 |
| Clària, J | 4 |
| Yan, Y | 1 |
| Xu, W | 1 |
| Qian, H | 2 |
| Si, Y | 1 |
| Zhu, W | 1 |
| Cao, H | 1 |
| Zhou, H | 1 |
| Mao, F | 1 |
| Salam, OM | 1 |
| Sleem, AA | 1 |
| Omara, EA | 1 |
| Hassan, NS | 3 |
| Lodhi, G | 1 |
| Singh, HK | 1 |
| Pant, KK | 1 |
| Hussain, Z | 1 |
| Sar, TK | 1 |
| Mandal, TK | 1 |
| Das, SK | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multiple-Dose Research Study on Safety Evaluation of the GD Antrodia Camphorata in 30 Healthy Adult Subjects[NCT01007656] | 31 participants (Actual) | Interventional | 2009-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01007656)
Timeframe: 90 days
| Intervention | g/dL (Mean) |
|---|---|
| GD Antrodia Camphorata | 4.74 |
(NCT01007656)
Timeframe: 90 days
| Intervention | U/L (Mean) |
|---|---|
| GD Antrodia Camphorata | 55.81 |
(NCT01007656)
Timeframe: 90 days
| Intervention | mg/dL (Mean) |
|---|---|
| GD Antrodia Camphorata | 9.32 |
(NCT01007656)
Timeframe: 90 days
| Intervention | mg/dL (Mean) |
|---|---|
| GD Antrodia Camphorata | 173.13 |
(NCT01007656)
Timeframe: 90 days
| Intervention | mg/dL (Mean) |
|---|---|
| GD Antrodia Camphorata | 0.84 |
Direct bilirubin is referred to as conjugated bilirubin, which is water-soluble. It's taken up by the liver cells and conjugated to form the water-soluble bilirubin diglucuronide. It's used to diagnose and/or monitor liver diseases, such as cirrhosis, hepatitis or gallstones. If direct bilirubin is elevated more than unconjugated bilirubin, there's typically a problem associated with decreased elimination of bilirubin by the liver cells. (NCT01007656)
Timeframe: 90 days
| Intervention | mg/dL (Mean) |
|---|---|
| GD Antrodia Camphorata | 0.10 |
(NCT01007656)
Timeframe: 90 days
| Intervention | g/dL (Mean) |
|---|---|
| GD Antrodia Camphorata | 2.51 |
(NCT01007656)
Timeframe: 90 days
| Intervention | mg/dL (Mean) |
|---|---|
| GD Antrodia Camphorata | 80.13 |
(NCT01007656)
Timeframe: 90 days
| Intervention | U/L (Mean) |
|---|---|
| GD Antrodia Camphorata | 17.42 |
(NCT01007656)
Timeframe: 90 days
| Intervention | U/L (Mean) |
|---|---|
| GD Antrodia Camphorata | 21.48 |
(NCT01007656)
Timeframe: 90 days
| Intervention | U/L (Mean) |
|---|---|
| GD Antrodia Camphorata | 21.94 |
Bilirubin is released into the blood when red blood cells break down. The liver uses bilirubin to make bile. Normally there is only a small amount of bilirubin in the blood. High levels may be caused by liver or blood problems. (NCT01007656)
Timeframe: 90 days
| Intervention | mg/dL (Mean) |
|---|---|
| GD Antrodia Camphorata | 0.73 |
The total protein test measures the total amount of two classes of proteins in the blood, albumin and globulin. (NCT01007656)
Timeframe: 90 days
| Intervention | g/dL (Mean) |
|---|---|
| GD Antrodia Camphorata | 7.25 |
(NCT01007656)
Timeframe: 90 days
| Intervention | mg/dL (Mean) |
|---|---|
| GD Antrodia Camphorata | 56.39 |
(NCT01007656)
Timeframe: 90 days
| Intervention | mg/dL (Mean) |
|---|---|
| GD Antrodia Camphorata | 5.47 |
14 reviews available for carbon tetrachloride and Liver Dysfunction
| Article | Year |
|---|---|
Melatonin's role in preventing toxin-related and sepsis-mediated hepatic damage: A review.
Topics: Aflatoxins; Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Hum | 2016 |
Role of hemostatic factors in hepatic injury and disease: animal models de-liver.
Topics: Animals; Bile Ducts; Blood Coagulation; Blood Coagulation Disorders; Carbon Tetrachloride; Chemical | 2016 |
Pharmacological actions of curcumin in liver diseases or damage.
Topics: Animals; Carbon Tetrachloride; Cholestasis; Curcuma; Curcumin; Humans; Iron; Liver; Liver Cirrhosis; | 2009 |
Carbon tetrachloride-induced lipid peroxidation: eicosanoid formation and their regulation by antioxidant nutrients.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-45 | 2003 |
Heterogeneity of the intrahepatic biliary epithelium.
Topics: 1-Naphthylisothiocyanate; Animals; Apoptosis; Bile Acids and Salts; Bile Duct Diseases; Bile Ducts, | 2006 |
Calcium and the mechanisms of liver necrosis.
Topics: Animals; Calcium; Carbon Tetrachloride; Cell Membrane; Chemical and Drug Induced Liver Injury; Galac | 1982 |
Alterations in chemically induced tissue injury related to all-trans-retinol pretreatment in rodents.
Topics: Animals; Cadmium; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Drug Synergism; Etha | 1995 |
Liver damage due to free radicals.
Topics: Alcoholism; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, A | 1993 |
Sinusoidal intercellular adhesion molecule-1 up-regulation precedes the accumulation of leukocyte function antigen-1-positive cells and tissue necrosis in a model of carbontetrachloride-induced acute rat liver injury.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Cell Separation; Chemical and Drug Induced Liver Injur | 1998 |
Some immunological aspects of liver function.
Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Antigens, Bacterial; B-Lymphocytes; Carbon | 1975 |
Theoretical aspects of enzymes in diagnosis. Why do serum enzymes change in hepatic, myocardial, and other diseases?
Topics: Animals; Carbon Tetrachloride; Cardiomyopathies; Enzymes; Humans; Liver; Liver Diseases; Reference S | 1989 |
[Biochemical semiology of the liver in ruminants].
Topics: 5'-Nucleotidase; Alanine Transaminase; Alkaline Phosphatase; Animals; Arginase; Artiodactyla; Aspart | 1986 |
Solvent toxicology: recent advances in the toxicology of benzene, the glycol ethers, and carbon tetrachloride.
Topics: Animals; Benzene; Blood Cells; Calcium; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury | 1987 |
Intravascular coagulation in liver disease.
Topics: Animals; Blood Coagulation Factors; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Di | 1974 |
1 trial available for carbon tetrachloride and Liver Dysfunction
| Article | Year |
|---|---|
Influence of liver's oxide-reductive homeostasis disorder for AKBR values in rabbit's arterial blood.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; Homeostasis; Ketone B | 2007 |
670 other studies available for carbon tetrachloride and Liver Dysfunction
| Article | Year |
|---|---|
Hepatoprotective effect and metabonomics studies of radix gentianae in rats with acute liver injury.
Topics: Administration, Oral; Animals; Biomarkers; Carbon Tetrachloride; Disease Models, Animal; Dose-Respon | 2021 |
Specnuezhenide reduces carbon tetrachloride-induced liver injury in mice through inhibition of oxidative stress and hepatocyte apoptosis.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Disease Models, Animal; Dose-Response Relationship, Drug; | 2022 |
Qi Sui Zhu Shui Plaster Inhibits AQP1 and MAPK Signaling Reduces Liver Damage Induced by Cirrhotic Ascites.
Topics: Animals; Aquaporin 1; Ascites; Body Weight; Carbon Tetrachloride; Humans; Liver Cirrhosis; Liver Dis | 2022 |
Oral supplementation of policosanol alleviates carbon tetrachloride-induced liver fibrosis in rats.
Topics: Animals; Antioxidants; Biomarkers; Carbon Tetrachloride; Caspase 3; Cytokines; Dietary Supplements; | 2022 |
Glia Maturation Factor-β Supports Liver Regeneration by Remodeling Actin Network to Enhance STAT3 Proliferative Signals.
Topics: Actins; Animals; Carbon Tetrachloride; Cyclin D1; Destrin; Glia Maturation Factor; Interleukin-6; Ja | 2022 |
Effect of 4-hydroxychalcone as preventive and curative treatment in Wistar rats with liver injury.
Topics: Animals; Carbon Tetrachloride; Chalcones; Chemical and Drug Induced Liver Injury; Dimethyl Sulfoxide | 2022 |
Rat Hepatic Stellate Cell Line CFSC-2G: Genetic Markers and Short Tandem Repeat Profile Useful for Cell Line Authentication.
Topics: Animals; Carbon Tetrachloride; Cell Line; Cell Line Authentication; Genetic Markers; Hepatic Stellat | 2022 |
Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Carbon Tetrac | 2022 |
Fibroblast Activation Protein Activates Macrophages and Promotes Parenchymal Liver Inflammation and Fibrosis.
Topics: Animals; Carbon Tetrachloride; Collagen; Fibroblasts; Fibrosis; Hepatitis; Humans; Inflammation; Liv | 2023 |
Fibroblast Activation Protein Activates Macrophages and Promotes Parenchymal Liver Inflammation and Fibrosis.
Topics: Animals; Carbon Tetrachloride; Collagen; Fibroblasts; Fibrosis; Hepatitis; Humans; Inflammation; Liv | 2023 |
Fibroblast Activation Protein Activates Macrophages and Promotes Parenchymal Liver Inflammation and Fibrosis.
Topics: Animals; Carbon Tetrachloride; Collagen; Fibroblasts; Fibrosis; Hepatitis; Humans; Inflammation; Liv | 2023 |
Fibroblast Activation Protein Activates Macrophages and Promotes Parenchymal Liver Inflammation and Fibrosis.
Topics: Animals; Carbon Tetrachloride; Collagen; Fibroblasts; Fibrosis; Hepatitis; Humans; Inflammation; Liv | 2023 |
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Flax; Hydrogen | 2023 |
Peptides from Antarctic krill (
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Euphausiacea; Kelch-Like ECH- | 2023 |
The Effect of Royal Jelly on Telomere Length and Some Biochemical Parameters in Wistar Albino Rats with Liver Damage Caused by Carbon Tetrachloride.
Topics: Animals; Antioxidants; Aspartate Aminotransferases; Bees; Carbon Tetrachloride; Cholesterol, LDL; Li | 2023 |
Hepatocyte survival and proliferation by fibroblast growth factor 7 attenuates liver inflammation, and fibrogenesis during acute liver injury via paracrine mechanisms.
Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Collagen; Culture Media, Conditioned; Fibroblast | 2023 |
[Effects of triterpenoids in fatty products on liver condition of laboratory animals with acute toxic hepatitis].
Topics: Alkaline Phosphatase; Animals; Animals, Laboratory; Antioxidants; Carbon Tetrachloride; Chemical and | 2023 |
Cakes fortified with papaya seeds effectively protects against CCl4-induced immunotoxicity.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Carica; Chemical and Drug Induced Liver Injury; Flavono | 2023 |
Nuclear accumulation of pyruvate kinase M2 promotes liver regeneration via activation of signal transducer and activator of transcription 3.
Topics: Animals; Carbon Tetrachloride; Cell Nucleus; Cell Proliferation; Cytoplasm; Hepatocytes; Intracellul | 2020 |
Group II muscarinic acetylcholine receptors attenuate hepatic injury via Nrf2/ARE pathway.
Topics: Animals; Antioxidant Response Elements; Carbon Tetrachloride; Cell Line; Chemical and Drug Induced L | 2020 |
Dysregulation of bile acids increases the risk for preterm birth in pregnant women.
Topics: Adolescent; Adult; Animals; Bile Acids and Salts; Carbon Tetrachloride; Cholic Acid; Disease Models, | 2020 |
Comparing distress of mouse models for liver damage.
Topics: Animals; Carbon Tetrachloride; Disease Models, Animal; Liver; Liver Cirrhosis; Liver Diseases; Mice | 2020 |
Perivenous Stellate Cells Are the Main Source of Myofibroblasts and Cancer-Associated Fibroblasts Formed After Chronic Liver Injuries.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Bile Ducts; Cancer-Associated Fibroblasts; Ca | 2021 |
Amelioration of Experimental Hepatotoxicity in Rats by Portulaca oleracea Linn. from Kashmir Himalaya.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Liver Diseases; | 2022 |
Hepatoprotective Effects of Polysaccharide from
Topics: Animals; Antioxidants; Carbon Tetrachloride; Disease Models, Animal; Free Radical Scavengers; Lipid | 2021 |
Extracellular vesicles from in vivo liver tissue accelerate recovery of liver necrosis induced by carbon tetrachloride.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Cell Proliferation; Disease Models, Animal; Extracellular | 2021 |
Evaluation of Brain Pharmacokinetic and Neuropharmacodynamic Attributes of an Antiepileptic Drug, Lacosamide, in Hepatic and Renal Impairment: Preclinical Evidence.
Topics: Acetamides; Administration, Oral; Animals; Anticonvulsants; Area Under Curve; Brain; Carbon Tetrachl | 2017 |
Placental growth factor silencing ameliorates liver fibrosis and angiogenesis and inhibits activation of hepatic stellate cells in a murine model of chronic liver disease.
Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Chronic Disease; Disease Models, | 2017 |
Hepatic Osteodystrophy: The Mechanism of Bone Loss in Hepatocellular Disease and the Effects of Pamidronate Treatment.
Topics: Animals; Bone and Bones; Bone Density Conservation Agents; Bone Diseases, Metabolic; Bone Remodeling | 2017 |
SOX9 predicts progression toward cirrhosis in patients while its loss protects against liver fibrosis.
Topics: Animals; Bile Ducts; Carbon Tetrachloride; Cells, Cultured; Disease Models, Animal; Disease Progress | 2017 |
BMSCs protect against liver injury via suppressing hepatocyte apoptosis and activating TGF-β1/Bax singling pathway.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Bone Marrow Cells; Carbon Tetrachloride; Cell Prolif | 2017 |
Allium tuberosum: Antidiabetic and hepatoprotective activities.
Topics: Animals; Antioxidants; Blood Glucose; Carbon Tetrachloride; Catalase; Chemical and Drug Induced Live | 2017 |
Reparative Effects of Astaxanthin-Hyaluronan Nanoaggregates against Retrorsine-CCl₄-Induced Liver Fibrosis and Necrosis.
Topics: Animals; Carbon Tetrachloride; Hyaluronic Acid; Liver Cirrhosis; Liver Diseases; Male; Necrosis; Pyr | 2018 |
Alleviation of carbon tetrachloride-induced hepatocellular damage and oxidative stress with a leaf extract of Glyphae brevis (Tiliaceae).
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Carb | 2018 |
Brachychiton populneus (Schott & Endl.) R.Br. ameliorate carbon tetrachloride induced oxidative stress through regulation of endoplasmic reticulum stress markers and inflammatory mediators in Sprague-Dawley male rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carbon Tetrachloride; Chromatography, High Pressure | 2018 |
Salinomycin ameliorates oxidative hepatic damage through AMP-activated protein kinase, facilitating autophagy.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Arachidonic Acid; Autophagy; Carbon Tetrachloride | 2018 |
Formulation and biopharmaceutical evaluation of supersaturatable self-nanoemulsifying drug delivery systems containing silymarin.
Topics: Animals; Biological Availability; Carbon Tetrachloride; Chemistry, Pharmaceutical; Disease Models, A | 2019 |
Camellia Oleifera Seed Extract Mildly Ameliorates Carbon Tetrachloride-Induced Hepatotoxicity in Rats by Suppressing Inflammation.
Topics: Alanine Transaminase; Animals; Camellia; Carbon Tetrachloride; Humans; Liver; Liver Diseases; Male; | 2019 |
Compositional characterisation of soluble apple polysaccharides, and their antioxidant and hepatoprotective effects on acute CCl4-caused liver damage in mice.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Hepatocytes; Humans; Liver; Liver Diseases; Male; Malon | 2013 |
Wu-Chia-Pi solution attenuates carbon tetrachloride-induced hepatic injury through the antioxidative abilities of its components acteoside and quercetin.
Topics: Administration, Oral; Animals; Antioxidants; Carbon Tetrachloride; Catalase; Chemical and Drug Induc | 2012 |
Hepatoprotection of 1β-hydroxyeuscaphic acid - the major constituent from Rubus aleaefolius against CCl4-induced injury in hepatocytes cells.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Cell Line; Disease Models, Animal; Dose-Response Relations | 2013 |
Type XVIII collagen is essential for survival during acute liver injury in mice.
Topics: Animals; Carbon Tetrachloride; Cell Death; Collagen Type XVIII; Extracellular Matrix; Gene Expressio | 2013 |
A high-fat diet and multiple administration of carbon tetrachloride induces liver injury and pathological features associated with non-alcoholic steatohepatitis in mice.
Topics: Alanine Transaminase; Animals; Apoptosis; Carbon Tetrachloride; Diet, High-Fat; Disease Models, Anim | 2013 |
Effects of yam peel extract against carbon tetrachloride-induced hepatotoxicity in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Dios | 2013 |
Investigation on flavonoid composition and anti free radical potential of Sida cordata.
Topics: Animals; Carbon Tetrachloride; Flavonoids; Free Radical Scavengers; gamma-Glutamyltransferase; Gluta | 2013 |
Attenuation of carbon tetrachloride-induced hepatic injury with curcumin-loaded solid lipid nanoparticles.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Curc | 2014 |
Reversing effects of lignans on CCl4-induced hepatic CYP450 down regulation by attenuating oxidative stress.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Cyclooctanes; Cytochrome P-450 Enzyme System; Dioxoles; | 2014 |
The effects of grape seed and colchicine on carbon tetrachloride induced hepatic damage in rats.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Colchicine; Dis | 2014 |
The protective effect of Phoenix dactylifera L. seeds against CCl4-induced hepatotoxicity in rats.
Topics: Administration, Oral; Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver I | 2014 |
Potential probiotic Escherichia coli 16 harboring the Vitreoscilla hemoglobin gene improves gastrointestinal tract colonization and ameliorates carbon tetrachloride induced hepatotoxicity in rats.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Carbon Tetrachloride; Catalase; Colony Count, Mi | 2014 |
Hepatoprotective and antioxidant activity of Melaleuca styphelioides on carbon tetrachloride-induced hepatotoxicity in mice.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Disease Models, Animal; Dose-Response Relationship, Dru | 2014 |
Hepatoprotective and antioxidant effects of wheat, carrot, and mango as nutraceutical agents against CCl4-induced hepatocellular toxicity.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Daucus carota; | 2015 |
Genoprotective and hepatoprotective effects of Guarana (Paullinia cupana Mart. var. sorbilis) on CCl4-induced liver damage in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Caffeine; Carbon Tetrachloride; DNA Dama | 2016 |
Anti-oxidative and hepatoprotective effects of lithospermic acid against carbon tetrachloride-induced liver oxidative damage in vitro and in vivo.
Topics: Animals; Antioxidants; Benzofurans; Carbon Tetrachloride; Cell Line; Depsides; Disease Models, Anima | 2015 |
Ubiquitin C-terminal hydrolase 1: A novel functional marker for liver myofibroblasts and a therapeutic target in chronic liver disease.
Topics: Animals; Biomarkers; Carbon Tetrachloride; Cell Proliferation; Cell Transdifferentiation; Cells, Cul | 2015 |
Oligonol Ameliorates CCl₄-Induced Liver Injury in Rats via the NF-Kappa B and MAPK Signaling Pathways.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biphenyl Compounds; Carbon | 2016 |
Protective Role of Grape Seed Proanthocyanidins Against Ccl4 Induced Acute Liver Injury in Mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Glutathione Peroxi | 2016 |
New pathways driving the experimental hepatoprotective action of tempol (4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl) against acute hepatotoxicity.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Caspase 3; Catalase; Cyclic N-Oxides; Gene Expression | 2016 |
Macrophage Migration Inhibitor Factor Upregulates MCP-1 Expression in an Autocrine Manner in Hepatocytes during Acute Mouse Liver Injury.
Topics: Animals; Autocrine Communication; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver | 2016 |
Protective Effects of Hydrolyzed Nucleoproteins from Salmon Milt against Ethanol-Induced Liver Injury in Rats.
Topics: Administration, Oral; Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Carbon | 2016 |
Augmenter of liver regeneration protects against carbon tetrachloride-induced liver injury by promoting autophagy in mice.
Topics: Animals; Autophagy; Blotting, Western; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; | 2017 |
Metron factor-1 prevents liver injury without promoting tumor growth and metastasis.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cells | 2008 |
Curcumin or saikosaponin a improves hepatic antioxidant capacity and protects against CCl4-induced liver injury in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Chem | 2008 |
Saengshik, a formulated health food, prevents liver damage in CCl4-induced mice and increases antioxidant activity in elderly women.
Topics: Agaricales; Aged; Aging; Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Live | 2008 |
Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) attenuates carbon tetrachloride hepatotoxicity by downregulating proinflammatory gene expression.
Topics: Animals; Biomarkers; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Chemical and Drug In | 2008 |
Hepatoprotective activity of Woodfordia fruticosa Kurz flowers against carbon tetrachloride induced hepatotoxicity.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Dose-Response Relationship, Drug; Female; Flowers; Glut | 2008 |
Hepatic protection by noni fruit juice against CCl(4)-induced chronic liver damage in female SD rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carbon Tetrachlori | 2008 |
Divergent transforming growth factor-beta signaling in hepatic stellate cells after liver injury: functional effects on ECE-1 regulation.
Topics: Animals; Aspartic Acid Endopeptidases; Bile Ducts; Carbon Tetrachloride; Cells, Cultured; Electropho | 2008 |
Hepatoprotective activity of Amaranthus spinosus in experimental animals.
Topics: Alanine Transaminase; Alkaline Phosphatase; Amaranthus; Animals; Aspartate Aminotransferases; Biliru | 2008 |
Effect of phenobarbital on hepatic injury induced by chronic carbon tetrachloride treatment.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Drug Synergism; Excitatory Am | 1981 |
Dietary trans-resveratrol bioavailability and effect on CCl4-induced liver lipid peroxidation.
Topics: Animals; Antioxidants; Biological Availability; Carbon Tetrachloride; Chemical and Drug Induced Live | 2009 |
Quantitative rat liver function test by galactose single point method.
Topics: Alanine Transaminase; Animals; Animals, Laboratory; Aspartate Aminotransferases; Carbon Tetrachlorid | 2008 |
The effects of short-term changes in dietary protein on the response of the liver to carbon tetrachloride injury.
Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Dietary Proteins; Liver Diseases | 1948 |
The pathogenesis of the liver lesion due to the administration of carbon tetrachloride.
Topics: Carbon Tetrachloride; Liver Diseases | 1948 |
Hepatoprotective activity of Phyllanthus reticulatus.
Topics: Animals; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, A | 2008 |
Hepatoprotective effect of Hibiscus hispidissimus Griffith, ethanolic extract in paracetamol and CCl4 induced hepatotoxicity in Wistar rats.
Topics: Acetaminophen; Animals; Biphenyl Compounds; Carbon Tetrachloride; Chemical and Drug Induced Liver In | 2008 |
Effect of schisandrin B and sesamin mixture on CCl(4)-induced hepatic oxidative stress in rats.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; D | 2009 |
The protective effect of montelukast sodium on carbon tetrachloride induced hepatopathy in rat.
Topics: Acetates; Alanine Transaminase; Animals; Bilirubin; Carbon Tetrachloride; Catalase; Chemical and Dru | 2009 |
Aquilegia vulgaris extract attenuates carbon tetrachloride-induced liver fibrosis in rats.
Topics: Animals; Aquilegia; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Fibrosis; Glutathi | 2009 |
Hepatocyte-specific deletion of heme oxygenase-1 disrupts redox homeostasis in basal and oxidative environments.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cloning, Molecular; Free Radi | 2008 |
Prevention of CCl4-induced liver damage by ginger, garlic and vitamin E.
Topics: Alkaline Phosphatase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Garlic; | 2007 |
Hepatoprotective effects of Artemisiae capillaris herba and Picrorrhiza rhizoma combinations on carbon tetrachloride-induced subacute liver damage in rats.
Topics: Alanine Transaminase; Animals; Artemisia; Aspartate Aminotransferases; Body Weight; Carbon Tetrachlo | 2008 |
Increased susceptibility to exacerbated liver injury in hypercholesterolemic ApoE-deficient mice: potential involvement of oxysterols.
Topics: Animals; Apolipoproteins E; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chemokine | 2009 |
Mesenchymal stem cells from human umbilical cords ameliorate mouse hepatic injury in vivo.
Topics: Animals; Carbon Tetrachloride; Cell Differentiation; Chemical and Drug Induced Liver Injury; DNA Pri | 2009 |
Hepatoprotective effects of misoprostol and silymarin on carbon tetrachloride-induced hepatic damage in rats.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA; Dose-Response Relationsh | 2009 |
Hepatoprotective effects of Calotropis gigantea extract against carbon tetrachloride induced liver injury in rats.
Topics: Animals; Antioxidants; Calotropis; Carbon Tetrachloride; Catalase; Dose-Response Relationship, Drug; | 2009 |
Pharmacokinetics of ceftriaxone in carbontetrachloride-induced hepatopathic and uranyl nitrate-induced nephropathic goats following single dose intravenous administration.
Topics: Animals; Anti-Bacterial Agents; Carbon Tetrachloride; Ceftriaxone; Female; Goats; Half-Life; Injecti | 2008 |
Hepatoprotective activity of six polyherbal formulations in CCl4-induced liver toxicity in mice.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Liver; Liver Diseases; Mice; | 2009 |
A novel function of thrombin-activatable fibrinolysis inhibitor during rat liver regeneration and in growth-promoted hepatocytes in primary culture.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Carboxypeptidase B2; Cell Division; Cells, Cultured; C | 2009 |
Hepatoprotective and curative properties of Kombucha tea against carbon tetrachloride-induced toxicity.
Topics: Acetobacter; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carbo | 2009 |
Mesenchymal stem cells showed the highest potential for the regeneration of injured liver tissue compared with other subpopulations of the bone marrow.
Topics: Animals; Bone Marrow Cells; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Coculture | 2009 |
Hepatoprotective effect of Trichosanthes cucumerina Var cucumerina L. on carbon tetrachloride induced liver damage in rats.
Topics: Administration, Oral; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease | 2009 |
Involvement of IQGAP3, a regulator of Ras/ERK-related cascade, in hepatocyte proliferation in mouse liver regeneration and development.
Topics: Animals; Carbon Tetrachloride; cdc42 GTP-Binding Protein; Cell Proliferation; Chemical and Drug Indu | 2009 |
Effects of embelin on lipid peroxidation and free radical scavenging activity against liver damage in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Benzoquinones; Carbon Tetrachloride; Free Radic | 2009 |
Thyroid modulation of TNF-dependent apoptosis and formation of chronic liver disease in endogenous intoxication in rats.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Caspase 3; Chemical and Drug Induced Liver Injury; Female; | 2009 |
Comparative study on the protective effects of Yinchenhao Decoction against liver injury induced by alpha-naphthylisothiocyanate and carbon tetrachloride.
Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Alkaline Phosphatase; Animals; Annonaceae; Aspartate | 2009 |
Comparative antihypertensive activities of losartan and HM70186 in rats with hepatic dysfunction.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Carbon Tetra | 2009 |
Hepatoprotective effect of Carissa carandas Linn root extract against CCl4 and paracetamol induced hepatic oxidative stress.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Apocynaceae; Aspartate Aminotransferases; Carbo | 2009 |
Hepatoprotective evaluation of Anogeissus latifolia: in vitro and in vivo studies.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carbon Tetrachlori | 2009 |
Carbon tetrachloride liver damage and acetylcholine esterase activity in the rabbit and rat.
Topics: Abdominal Injuries; Acetylcholine; Animals; Carbon Monoxide; Carbon Monoxide Poisoning; Carbon Tetra | 1947 |
Effect of carbon tetrachloride liver damage in the rabbit and rat on acetylcholine esterase activity.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Carbon Tetrachloride; Liver Diseases; Rabbits; Rats | 1947 |
CCl4-induced hepatic injury in mice fed a Western diet is associated with blunted healing.
Topics: Alanine Transaminase; Animals; Biomarkers; Blotting, Western; Carbon Tetrachloride; Chemical and Dru | 2010 |
Protective effect of recombinant human IL-1Ra on CCl4-induced acute liver injury in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cell Proliferation | 2010 |
Resveratrol and liver disease: from bench to bedside and community.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carbon Tetrachloride; Cytokine | 2010 |
Protective effects of baicalin on carbon tetrachloride induced liver injury by activating PPARγ and inhibiting TGFβ1.
Topics: Animals; Blotting, Western; Carbon Tetrachloride; Disease Models, Animal; Dose-Response Relationship | 2011 |
Role of IL-6 trans-signaling in CCl₄induced liver damage.
Topics: Animals; Blotting, Western; Carbon Tetrachloride; Cytochrome P-450 CYP2E1; Cytokine Receptor gp130; | 2010 |
Antioxidant activity and hepatoprotective effects of whey protein and Spirulina in rats.
Topics: Administration, Oral; Animals; Antioxidants; Carbon Tetrachloride; Chelating Agents; Dose-Response R | 2011 |
Anti-fibrotic effect of chorionic plate-derived mesenchymal stem cells isolated from human placenta in a rat model of CCl(4)-injured liver: potential application to the treatment of hepatic diseases.
Topics: Animals; Blotting, Western; Carbon Tetrachloride; Cell Differentiation; Cell Line; Cells, Cultured; | 2010 |
In vivo biodistribution, anti-inflammatory, and hepatoprotective effects of liver targeting dexamethasone acetate loaded nanostructured lipid carrier system.
Topics: Animals; Anti-Inflammatory Agents; Carbon Tetrachloride; Carrageenan; Dexamethasone; Drug Carriers; | 2010 |
Liver necrosis and the induction of carbon tetrachloride hepatomas in strain A mice.
Topics: Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Liver; Liver Diseases; Liver Neoplasms; Mi | 1946 |
Hepatoprotective and antioxidant effects of Hibiscus sabdariffa extract against carbon tetrachloride-induced hepatocyte damage in Cyprinus carpio.
Topics: Animals; Antioxidants; Aquaculture; Carbon Tetrachloride; Carps; Dose-Response Relationship, Drug; F | 2011 |
A sesquiterpenol extract potently suppresses inflammation in macrophages and mice skin and prevents chronic liver damage in mice through JNK-dependent HO-1 expression.
Topics: Animals; Carbon Tetrachloride; Cryptomeria; Cyclooxygenase 2 Inhibitors; Dermatitis; Dinoprostone; H | 2011 |
Hepatocyte nuclear factor 1β induced by chemical stress accelerates cell proliferation and increases genomic instability in mouse liver.
Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Genetic Vectors; Genomic Instability; Hepatocyte | 2011 |
Liver-specific loss of glucose-regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in mice.
Topics: Alanine Transaminase; Animals; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Inju | 2011 |
Hepatoprotective properties of Caesalpinia sappan Linn. heartwood on carbon tetrachloride induced toxicity.
Topics: Animals; Caesalpinia; Carbon Tetrachloride; Cell Separation; Hepatocytes; Liver; Liver Diseases; Phy | 2010 |
Antioxidant and hepatoprotective effect of the ethyl acetate extract of Enicostemma axillare (Lam). Raynal against CCL4-induced liver injury in rats.
Topics: Acetates; Animals; Antioxidants; Carbon Tetrachloride; Chromatography, Thin Layer; Gentianaceae; Kid | 2010 |
Hepatoprotective effects of polyprenols from Ginkgo biloba L. leaves on CCl4-induced hepatotoxicity in rats.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; Ginkgo | 2011 |
Differentiation and transplantation of human induced pluripotent stem cell-derived hepatocyte-like cells.
Topics: Animals; Carbon Tetrachloride; Cell Differentiation; Cell Line; Disease Models, Animal; Embryonic St | 2013 |
Evaluation of the liver protection and toxicity of Da-Huang-Zhe-Chong pill in rats.
Topics: Animals; Carbon Tetrachloride; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Inje | 2012 |
[Expression of NMDA receptor subunits in rat prefrontal cortex with CCL4-induced hepatic damage after a treatment with Rosmarinus officinalis L].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Liver Diseases; Male; Plant E | 2012 |
Bacterial translocation and changes in the intestinal microbiome in mouse models of liver disease.
Topics: Animals; Bacterial Translocation; Carbon Tetrachloride; Cholestasis; Disease Models, Animal; Intesti | 2012 |
Protective effect of Öküzgözü (Vitis vinifera L. cv.) grape juice against carbon tetrachloride induced oxidative stress in rats.
Topics: Animals; Beverages; Brain; Carbon Tetrachloride; Fruit; Humans; Kidney; Lipid Peroxidation; Liver; L | 2012 |
Serum and liver tissue bio-element levels, and antioxidant enzyme activities in carbon tetrachloride-induced hepatotoxicity: protective effects of royal jelly.
Topics: Animals; Antioxidants; Blood Chemical Analysis; Carbon Tetrachloride; Enzymes; Fatty Acids; Humans; | 2012 |
Hepatoprotection with a chloroform extract of Launaea procumbens against CCl4-induced injuries in rats.
Topics: Animals; Antioxidants; Aspartate Aminotransferases; Asteraceae; Carbon Tetrachloride; Glutathione Pe | 2012 |
Branched-chain amino acid-enriched nutrients stimulate antioxidant DNA repair in a rat model of liver injury induced by carbon tetrachloride.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Amino Acids, Branched-Chain; Animals; Antioxidants; Biomarkers; Blottin | 2012 |
Hepatoprotective effects of Juglans regia extract against CCl4-induced oxidative damage in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Carb | 2013 |
Protective effects of lipocalin-2 (LCN2) in acute liver injury suggest a novel function in liver homeostasis.
Topics: Acute Disease; Acute-Phase Proteins; Animals; Apoptosis; Bile Ducts; Blotting, Western; Carbon Tetra | 2013 |
Evaluation of antioxidant activities of water-soluble polysaccharides from brown alga Hizikia fusiformis.
Topics: Animals; Antioxidants; Biomarkers; Biphenyl Compounds; Carbon Tetrachloride; Free Radical Scavengers | 2013 |
Antioxidant and antihepatotoxic activities of Phellinus rimosus (Berk) Pilat.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Cell Extracts; Chemical and Drug Induced Liver Injury; | 2002 |
Hepatobiliary organic anion transporters are differentially regulated in acute toxic liver injury induced by carbon tetrachloride.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Carrier Proteins; CCAAT-Enhancer-Binding Proteins; Che | 2002 |
Protective effect of carnosol on CCl(4)-induced acute liver damage in rats.
Topics: Abietanes; Acute Disease; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dis | 2002 |
Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E.
Topics: Adenoviridae; Animals; Calcium-Binding Proteins; Carbon Tetrachloride; Carrier Proteins; Cell Cycle | 2002 |
Protective effect of a lignan-containing flaxseed extract against CCl(4)-induced hepatic injury.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA Damage; Drug Administrati | 2002 |
Enzyme release from injured, preserved, and ex vivo reperfused liver does not indicate malfunction.
Topics: Acute Disease; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Che | 2002 |
Hepatoprotective pyrrole derivatives of Lycium chinense fruits.
Topics: Animals; Carbon Tetrachloride; Dose-Response Relationship, Drug; Drug Antagonism; Fruit; Hepatocytes | 2003 |
Protective effect of rutin on paracetamol- and CCl4-induced hepatotoxicity in rodents.
Topics: Acetaminophen; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models | 2002 |
Foxf1 +/- mice exhibit defective stellate cell activation and abnormal liver regeneration following CCl4 injury.
Topics: Actins; Animals; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chemokine | 2003 |
Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells.
Topics: Acute Disease; Adenoviridae; Animals; Antisense Elements (Genetics); Carbon Tetrachloride; Carrier P | 2003 |
The formation of oxidative stress condition in the experimental chemically induced hepatotoxicity.
Topics: Acetaminophen; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models | 2002 |
[The further studies on the pharmacological actions of Bupleurum smithii var. parvifolium].
Topics: Analgesics; Animals; Bupleurum; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Drugs, | 1998 |
Biomedicine. Love, honor, and protect (your liver).
Topics: Animals; Carbon Tetrachloride; Cell Communication; Cell Division; Chemical and Drug Induced Liver In | 2003 |
Angiogenesis-independent endothelial protection of liver: role of VEGFR-1.
Topics: Animals; Carbon Tetrachloride; Cell Division; Cells, Cultured; Chemical and Drug Induced Liver Injur | 2003 |
Protective effects of fermented filtrate from Antrodia camphorata in submerged culture against CCl4-induced hepatic toxicity in rats.
Topics: Animals; Carbon Tetrachloride; Cell Death; Cell Line; Chemical and Drug Induced Liver Injury; Cinnam | 2003 |
Effect of D-003, a mixture of high molecular weight primary acids from sugar cane wax, on CL4C-induced liver acute injury in rats.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Fatty Acids; He | 2002 |
Combined histomorphometric and gene-expression profiling applied to toxicology.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Data Interpretation, Statisti | 2003 |
Antioxidative and hepatoprotective effects of Antrodia camphorata extract.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Basidiomycota; Biphenyl Co | 2003 |
Glycosmis arborea extract as a hepatoprotective agent.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Body Weight; Carbon Tetrachlorid | 2003 |
Renal effects of selective cyclooxygenase inhibition in experimental liver disease.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooxygenase 1; Cyclooxygen | 2003 |
Clinical usefulness of edaravone for acute liver injury.
Topics: Animals; Antipyrine; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Edarav | 2003 |
Protective effect of central thyrotropin-releasing hormone on carbon tetrachloride-induced acute hepatocellular necrosis in rats.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atropine; Carbon Tetrachloride; Che | 2003 |
Alleviating effects of si-ni-san, a traditional Chinese prescription, on experimental liver injury and its mechanisms.
Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver Injury; Dose-Respons | 2003 |
Cortisone and liver function.
Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cortisone; Liver Diseases; Liver Function Test | 1953 |
Adenylpyrophosphates in the fatty livers of guinea-pigs produced by carbon tetrachloride.
Topics: Adenosine Triphosphate; Carbon Tetrachloride; Fatty Liver; Guinea Pigs; Liver Diseases | 1952 |
Morphological changes in the liver of rats treated with various chemical agents.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Child; Diarrhea; Infant; Infant Nutri | 1953 |
[The effect of desoxycorticosterone and cortisone on experimental liver diseases].
Topics: Carbon Tetrachloride; Cortisone; Desoxycorticosterone; Liver; Liver Diseases | 1953 |
Studies in fibrosis of the liver induced by carbon tetrachloride. I. Relation between hepatocellular injury and new formation of fibrous tissue.
Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Liver; Liver Diseases | 1954 |
[Paper-electrophoretic studies on experimental liver damages in rat].
Topics: Animals; Blood Proteins; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Electrophoresis; Live | 1953 |
[Trials on fatty degeneration of the liver].
Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Choline; Liver Diseases; Methionine; Poisoning | 1953 |
The serum iron in experimental hepatocellular necrosis.
Topics: Blood; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Iron; Liver Diseases | 1954 |
[Experimental studies on the significance of purines as liver-protecting factors].
Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Liver Diseases; Poisoning; Protective Agents; | 1953 |
[Effect of 1-ethinyl-cyclohexylcarbamate on damaged liver].
Topics: Abdominal Injuries; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cyclohexanes; Liver; Liver | 1954 |
[Liver damage as a sequel to chronic industrial poisoning with carbon hydrochloride].
Topics: Carbon; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chronic Disease; Humans; Liver Disease | 1955 |
[Determination of the steatogenic effects of experimental carbon tetrachloride poisoning].
Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Lipid Metabolism; Lipids; Liver Diseases; Pois | 1955 |
[Studies of various biological activities of a gastric mucoprotein from swine. II. Effect on hepatic steatosis caused by carbon tetrachloride].
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Fatty Liver; Liver Diseases; Mucoprot | 1955 |
[Metabolic functions of tocopherols (alpha & gamma) and comparison with methylene blue in experimental steatonecrosis induced by carbon tetrachloride].
Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Fat Necrosis; Liver Diseases; Methylene Blue; | 1955 |
A study of the relation of adrenal cortex to acute carbon tetrachloride hepatopathy.
Topics: Adrenal Cortex; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Liver Diseases | 1956 |
A study of the effects of the surgical treatment of experimentally produced liver disease.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Hepatitis; Hypertension; Liver Cirrho | 1956 |
[Behavior of the phosphoglyceromutase activity of blood in experimental carbon tetrachloride necrosis of the liver].
Topics: Carbon Tetrachloride; Intramolecular Transferases; Liver Diseases; Necrosis; Phosphoglycerate Mutase | 1956 |
[Behavior of the phosphoglyceromutase activity of blood in experimental carbon tetrachloride necrosis of the liver].
Topics: Carbon Tetrachloride; Intramolecular Transferases; Liver Diseases; Necrosis; Phosphoglycerate Mutase | 1956 |
[Behavior of the phosphoglyceromutase activity of blood in experimental carbon tetrachloride necrosis of the liver].
Topics: Carbon Tetrachloride; Intramolecular Transferases; Liver Diseases; Necrosis; Phosphoglycerate Mutase | 1956 |
[Behavior of the phosphoglyceromutase activity of blood in experimental carbon tetrachloride necrosis of the liver].
Topics: Carbon Tetrachloride; Intramolecular Transferases; Liver Diseases; Necrosis; Phosphoglycerate Mutase | 1956 |
[Study of the changes in some enzymes in the blood and liver in experimental carbon-tetrachloride-induced liver disease].
Topics: Carbon; Carbon Tetrachloride; Enzymes; Hepatitis; Liver Diseases | 1956 |
[Effects of testosterone propionate on hepatic lesions induced by prolonged administration of carbon tetrachloride in rats].
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Liver Diseases; Rats; Testosterone; T | 1957 |
[Glutamic dehydrogenase and alcohol dehydrogenase of blood in various conditions of experimental hepatic necrosis: hepatitis due to MHV-3 virus, acute poisoning due to carbon tetrachloride].
Topics: Alcohol Dehydrogenase; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Glutamate Dehydrogenase | 1956 |
[Lipotropic & liver protective effect of pantethine in experimental liver diseases induced by Handler diet & carbon tetrachloride].
Topics: Carbon Tetrachloride; Diet; Lipotropic Agents; Liver Diseases; Pantetheine; Pantothenic Acid; Sulfid | 1957 |
[Protective effect of aspartic acid on experimental hepatic lesions].
Topics: Aspartic Acid; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Liver Diseases | 1957 |
[Histometric research on the effect of ACTH on hepatic fibrosis caused by carbon tetrachloride].
Topics: Adrenocorticotropic Hormone; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Liver Cirrhosis; | 1957 |
Studies on influence of protein on the liver injury due to chloroform and carbon tetrachloride.
Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chloroform; Liver Diseases; Proteins | 1958 |
[Enolase activity of plasma in experimental hepatic necrosis induced by carbon tetrachloride].
Topics: Carbon Tetrachloride; Hydro-Lyases; Liver Diseases; Phosphopyruvate Hydratase | 1958 |
[Effect of deproteinized honey solutions on liver function in animals given carbon tetrachloride].
Topics: Animals; Carbon Tetrachloride; Honey; Liver; Liver Diseases | 1958 |
[Histochemical investigations on the carbon tetrachloride damaged rabbit liver].
Topics: Animals; Carbon Tetrachloride; Liver Diseases; Rabbits | 1959 |
[Experiments on the therapy of experimental liver injuries caused by carbon tetrachloride].
Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Liver Diseases | 1959 |
[Thermocoagulation of rat serum as a criterion of liver damage after experimental carbon tetrachloride poisoning].
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Electrocoagulation; Liver Diseases; R | 1959 |
Calpain released from dying hepatocytes mediates progression of acute liver injury induced by model hepatotoxicants.
Topics: Acetaminophen; Animals; Blotting, Western; Calpain; Carbon Tetrachloride; Carrier Proteins; Chemical | 2003 |
[Effects of vitamin B-12 alone and associated with folic acid, vitamin C and vitamin PP on hepatic lesions and on humoral behavior in the course of chronic poisoning with carbon tetrachloride. Experimental research].
Topics: Ascorbic Acid; Carbon Tetrachloride; Chronic Disease; Folic Acid; Humans; Liver Diseases; Niacinamid | 1961 |
The role of hepatic damage on development of the Walker 256 carcinosarcoma.
Topics: Animals; Carbon Tetrachloride; Carcinoma 256, Walker; Liver; Liver Diseases; Liver Neoplasms, Experi | 1960 |
[Oxidation of sodium thiosulfate in the course of cholostasis induced by ligation of the choledochus and liver disease induced by carbon tetrachloride].
Topics: Carbon Tetrachloride; Common Bile Duct; Ligation; Liver Diseases; Thiosulfates | 1961 |
The effect of dietary cirrhosis and CC1- poisoning on glucuronyl transferase activity of rat liver.
Topics: Animals; Carbon Tetrachloride; Diet; Liver Cirrhosis; Liver Diseases; Nutrition Disorders; Rats; Tra | 1961 |
[Sulfanylurea and hepatic damage in the normal rat and the rat with steatosis caused by carbon tetrachloride].
Topics: Abdominal Injuries; Animals; Carbon Tetrachloride; Hypoglycemic Agents; Liver; Liver Diseases; Rats | 1960 |
Presence of two glutamic-oxalacetic transaminases in serum of dogs following acute injury of the liver.
Topics: Animals; Carbon Tetrachloride; Dogs; Health Services; Liver Diseases; Transaminases | 1961 |
Effects of thioctic acid and adenosine triphosphate on liver diseases. I. Influences of thioctic acid and adenosine triphosphate on the liver of the mice damaged with carbon tetrachloride.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Carbon Tetrachloride; Leadership; Liver Diseas | 1961 |
The role of adrenocortical function in the liver damage and regeneration in mice treated with carbon tetrachloride (CC1-4).
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Carbon Tetrachloride; Liver Diseases; Mice; Ox | 1961 |
Liver regeneration after partial hepatectomy in carbon tetrachloride-induced cirrhosis in the rat.
Topics: Animals; Carbon Tetrachloride; Digestion; Hepatectomy; Liver; Liver Cirrhosis; Liver Cirrhosis, Expe | 1961 |
Reversible nature of liver cell damage due to carbon tetrachloride as demonstrated by the use of phenergan.
Topics: Carbon Tetrachloride; Liver; Liver Diseases; Promethazine | 1961 |
[Liver damage in acute occupational carbon tetrachloride poisoning].
Topics: Abdominal Injuries; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Fructose-Bisphosphate Aldo | 1960 |
[Investigations on the ability of glucuronic conjugation of the damaged liver treated with methylthiouracil].
Topics: Abdominal Injuries; Carbohydrate Metabolism; Carbon Tetrachloride; Glucuronates; Liver; Liver Diseas | 1960 |
Influence of a liver preparation on liver of cats receiving carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Cats; Leadership; Liver Diseases; Liver Extracts | 1961 |
[Study of the hepatic release of vitamin B12 labeled by cobalt 60 in the course of experimental necrosis due to carbon tetrachloride].
Topics: Carbon Tetrachloride; Cobalt; Corrinoids; Liver Diseases; Necrosis; Vitamin B 12 | 1959 |
[Studies on the hormonal treatment of chronic liver diseases. Note V. Action of cortisone acetate on the histological and histochemical picture and on the hexosamine and hydroxyproline content of the cirrhotic liver (carbon tetrachloride-induced)].
Topics: Amino Sugars; Animals; Carbon Tetrachloride; Cortisone; Hexosamines; Hydroxyproline; Liver Cirrhosis | 1959 |
[Observations on siderosis in rats with experimental hepatic damage].
Topics: Animals; Carbon Tetrachloride; Liver; Liver Diseases; Rats; Siderosis | 1959 |
[Protective effect of 5-hydroxytryptamine against the hepatocellular damage induced by carbon tetrachloride in rats].
Topics: Abdominal Injuries; Animals; Carbon Tetrachloride; Liver; Liver Diseases; Rats; Serotonin | 1959 |
Inverse histochemical distribution of fat and oxidative enzymes in fatty livers produced by carbon tetrachloride.
Topics: Carbon Tetrachloride; Electron Transport Complex II; Fats; Fatty Liver; Liver Diseases; Oxidation-Re | 1960 |
Acute carbon tetrachloride intoxication. Report of a case of inhalation intoxication with severe liver damage followed by complete recovery.
Topics: Abdominal Injuries; Carbon Tetrachloride; Drug-Related Side Effects and Adverse Reactions; Liver; Li | 1959 |
[On the effect of androgen in toxic and dietetic liver damage. An experimental animal study].
Topics: Androgens; Carbon Tetrachloride; Diet; Dietetics; Liver; Liver Diseases; Protein Deficiency; Testost | 1959 |
Concurrent experimental lesions in the liver due to carbon tetrachloride and alpha-naphthyl-isothiocyanate.
Topics: Carbon Tetrachloride; Isothiocyanates; Liver Diseases; Thiocyanates | 1960 |
Electron microscopic cyto-histopathology. (18). Electron microscopic studies on vacuolar degeneration. Changes observed in liver cells and kidney tubules by acute carbon tetrachloride and diethylene glycol poisoning.
Topics: Carbon Tetrachloride; Electrons; Ethylene Glycols; Kidney Diseases; Kidney Tubules; Liver Diseases | 1962 |
[Changes in the activity of individual enzymes in the liver in cirrhosis produced by carbon tetrachloride in rats].
Topics: Animals; Carbon Tetrachloride; Enzymes; Fibrosis; Liver Cirrhosis; Liver Diseases; Rats | 1961 |
Effect of vitamin B12 on liver regeneration after carbon tetrachloride injury.
Topics: Carbon Tetrachloride; Hematinics; Liver Diseases; Liver Regeneration; Regeneration; Vitamin B 12 | 1962 |
[Urinary elimination of free histamine in normal rats and rats poisoned with CC1-4].
Topics: Animals; Carbon Tetrachloride; Histamine; Liver Diseases; Rats | 1961 |
Serum enzyme and B12 changes in CC14 hepatotoxicity.
Topics: Carbon Tetrachloride; Enzymes; Gastrointestinal Diseases; Humans; Liver Diseases | 1962 |
Deposition of protein in damaged liver cells.
Topics: Abdominal Injuries; Carbon Tetrachloride; Coloring Agents; Liver; Liver Diseases; Proteins; Staining | 1962 |
[Serum sorbitol dehydrogenase activity in liver lesions produced with tetrachloromethane in experimental conditions].
Topics: Carbon Tetrachloride; Humans; L-Iditol 2-Dehydrogenase; Liver Diseases; Oxidoreductases | 1961 |
[Studies on the activity of some enzymes in the blood serum in experimental carbon tetrachloride liver injuries].
Topics: Carbon Tetrachloride; Liver Diseases; Serum; Transaminases | 1961 |
Inhibition by aminoacetonitrile of early lesions induced in the liver of rats by carbon tetrachloride.
Topics: Aminoacetonitrile; Animals; Carbon Tetrachloride; Cyanides; Liver Diseases; Rats | 1962 |
[Protective action of a ribonucleoside mixture in acute experimental carbon tetrachloride poisoning].
Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Liver Diseases; Ribonucleosides | 1962 |
Effect of hepatocellular injury on gastric secretion in dogs.
Topics: Abdominal Injuries; Animals; Carbon Tetrachloride; Digestion; Dogs; Gastric Juice; Liver Diseases | 1961 |
Lipid metabolism in hepatic injury. 3. Effect of orotic acid on serum and liver lipid levels in rats with subacute hepatic injury induced by the repeated injections of carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Lipid Metabolism; Lipids; Liver Disea | 1962 |
Role of sympathetic discharge in the hepatotoxic action of carbon tetrachloride.
Topics: Carbon Tetrachloride; Gastrointestinal Diseases; Guanethidine; Liver Diseases; Pempidine; Phenoxyben | 1962 |
Hepatic cell degeneration. Correlation of fine structural with chemical and histochemical changes in hepatic cell injury produced by carbon tetrachloride in rats.
Topics: Animals; Carbon Tetrachloride; Hepatocytes; Liver Diseases; Rats | 1963 |
[The effect of tuberculosis on chronic liver disorders produced by carbon tetrachloride in rats].
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Liver Diseases; Rats; Tuberculosis | 1963 |
[The activity of DPNH- and TPNH-related microsomal enzymes in the carbon tetrachloride-damaged mouse liver].
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Dihydrolipoamide Dehydrogenase; Liver | 1962 |
[The behavior of mononucleotides and ribonucleic acids in the supernatant fraction of the mouse liver after carbon tetrachloride damage].
Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Liver Diseases; Nucleoproteins; Nucleotides; R | 1962 |
Effect of administration of glucuronic acid in rats treated with carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Glucuronates; Glucuronic Acid; Liver | 1963 |
Lipoproteins, cholesterol and phospholipids in sera of rabbits following ligation of the common bile duct or injection of carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Cholesterol; Common Bile Duct; Jaundice; Jaundice, Obstructive; Ligat | 1963 |
SERUM LIPOPROTEIN LEVELS IN RATS WITH LIVER DAMAGE INDUCED BY CARBON TETRACHLORIDE.
Topics: Blood Proteins; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Live | 1963 |
[ACTION OF ALPHA-TOCOPHEROL IN EXPERIMENTAL HEPATIC NECROSIS BY CARBON TETRACHLORIDE].
Topics: Alanine Transaminase; alpha-Tocopherol; Aspartate Aminotransferases; Carbon Tetrachloride; Carbon Te | 1963 |
[EFFECT OF ASCORBIC ACID ON EXPERIMENTAL LIVER DAMAGE. I. SERUM TRANSAMINASE IN CARBON TETRACHLORIDE LESIONS].
Topics: Alanine Transaminase; Ascorbic Acid; Aspartate Aminotransferases; Blood; Carbon Tetrachloride; Carbo | 1963 |
[THE EFFECT OF SERUM FROM PARTIALLY HEPATECTOMIZED RATS ON CHRONIC LIVER DAMAGE CAUSED BY CARBON TETRACHLORIDE].
Topics: Blood; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; | 1963 |
[EXAMINATION OF THE EFFECT OF SEROTONIN IN THE EARLY PHASE OF LIVER DAMAGE CAUSED BY CARBON TETRACHLORIDE].
Topics: Aspartate Aminotransferases; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug | 1963 |
[A STUDY OF THE FREE AMINO ACIDS IN THE SERUM OF LIVER DISEASES].
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Blood; Carbon Tetrachloride; Chemical and Drug Ind | 1964 |
[FORMATION OF THE SERUM PROTEIN-BOUND CARBOHYDRATE- AND HAPTOGLOBIN-LEVEL IN EXPERIMENTAL LIVER DAMAGE IN RATS].
Topics: Biphenyl Compounds; Blood Proteins; Carbohydrates; Carbon Tetrachloride; Chemical and Drug Induced L | 1964 |
[THE EFFECT OF SERUM FROM SUBTOTALLY HEPATECTOMIZED RATS ON CHRONIC LIVER DAMAGE CAUSED BY CARBON TETRACHLORIDE].
Topics: Adenosine Triphosphatases; Alkaline Phosphatase; Carbon Tetrachloride; Carbon Tetrachloride Poisonin | 1964 |
THE SYNTHESIS OF SULPHATED MUCOPOLYSACCHARIDE AT SITES OF HEPATIC FIBROSIS INDUCED BY CARBON TETRACHLORIDE, AMYLOIDOSIS AND THE IMPLANTATION OF CATGUT.
Topics: Amyloidosis; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Catgut; Chemical and Drug Induced | 1964 |
[THE REGENERATIVE REACTION TO A SINGLE ADMINISTRATION OF CARBON TETRACHLORIDE IN DIFFERENT TISSUES].
Topics: Animals; Autoradiography; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Division; Hyper | 1964 |
A CORRELATION OF THE EFFECTS OF CERVICAL CORDOTOMY, HYPOTHERMIA AND CATECHOLAMINES ON CARBON TETRACHLORIDE-INDUCED HEPATIC NECROSIS.
Topics: Body Temperature; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Catecholamines; Chemical and | 1965 |
[MINICIONE G, PAGNINI P, GORI F: (DEVELOPMENT OF EXPERIMENTAL CIRRHOSIS FROM CARBON TETRACHLORIDE IN THE "REGENERATED" LIVER OF RATS SUBJECTED TO WIDE HEPATECTOMY)].
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Hepatectomy; Liver Cirrhosis; Liver C | 1964 |
Serum aldolase in experimental liver necrosis.
Topics: Blood; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Fructose-Bisphosphate Aldolase; Liver; | 1955 |
[Behavior of some systems involved in protein synthesis (dipeptidase-ribonucleic acid) in hepatic damage induced by the administration of carbon tetrachloride to rats].
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Dipeptidases; Liver; Liver Diseases; | 1955 |
[Changes in the DPN and DPNH level of the normal and damaged liver before and after glucose treatment].
Topics: Abdominal Injuries; Carbon Tetrachloride; Coenzymes; Glucose; Liver; Liver Diseases; NAD | 1959 |
A study of vitamin B12 protection in experimental liver injury to the rat by carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Hematinics; Liver Diseases; Rats; Vitamin B 12 | 1959 |
Effect of partial hepatectomy on mitosis rate in carbon tetrachloride-induced liver damage of parabiotic rats.
Topics: Animals; Carbon Tetrachloride; Hepatectomy; Liver; Liver Diseases; Mitosis; Parabiosis; Rats | 1960 |
[Experimental contribution to the study of a pharmacological combination of substances of hepatoprotective action].
Topics: Carbon Tetrachloride; Liver Diseases | 1959 |
[Effects of testosterone propionate in massive doses on experimental carbon tetrachloride-induced hepatopathy].
Topics: Carbon Tetrachloride; Liver Diseases; Testosterone; Testosterone Propionate | 1959 |
Carbon tetrachloride poisoning of ewes on a low selenium ration.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Female; Liver Diseases; Selenium; She | 1960 |
[Effects of N-(4-aminobenzosulfonyl)-N'-butylurea (oranil, invenol) on carbon tetrachloride-induced fibrosis in rabbits].
Topics: Animals; Carbon Tetrachloride; Carbutamide; Lagomorpha; Liver Diseases; Rabbits; Urea | 1959 |
Biochemical changes in carbon tetrachloride fatty liver: concentration of carbon tetrachloride in liver and blood.
Topics: Carbon Tetrachloride; Fatty Liver; Liver Diseases | 1960 |
[Comparative studies on the enzyme activity in rat liver and serum after experimental liver damage by carbon tetrachloride and under the effect of cysteine-acetylhomocysteine thiolactone].
Topics: Abdominal Injuries; Animals; Carbon Tetrachloride; Cysteine; Enzymes; Lactones; Liver; Liver Disease | 1960 |
[On the dynamics of changes in transaminase activity in toxic liver injuries].
Topics: Carbon Tetrachloride; Liver Diseases; Transaminases | 1962 |
[Urinary elimination of free histamine in normal and CCI-4 intoxicated rats after hypodermic administration of histamine phosphate].
Topics: Animals; Carbon Tetrachloride; Histamine; Liver Diseases; Rats | 1961 |
[Preliminary research by means of gas chromatography on the composition in fatty acids of the liver of the rat poisoned by CCl-4].
Topics: Animals; Carbon Tetrachloride; Chromatography, Gas; Fatty Acids; Lipid Metabolism; Liver Diseases; R | 1962 |
Role of fibroblast growth factor type 1 and 2 in carbon tetrachloride-induced hepatic injury and fibrogenesis.
Topics: Actins; Animals; Bile Acids and Salts; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; | 2003 |
4-Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cells.
Topics: Actins; Acute Disease; Aldehydes; Animals; Apoptosis; Carbon Tetrachloride; Cell Death; Cells, Cultu | 2004 |
The regulation of liver regeneration by the plasmin/alpha 2-antiplasmin system.
Topics: alpha-2-Antiplasmin; Animals; Carbon Tetrachloride; Cell Division; Chemical and Drug Induced Liver I | 2004 |
Electrophysiological effects of anthopleurin-Q on rat hepatocytes.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Calcium; Calcium Channels; Carbon Tetrac | 2004 |
Commitment of bone marrow cells to hepatic stellate cells in mouse.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Carbon Tetrachloride; Cell Lineage; Cells, | 2004 |
Lipotropic agents in liver damage produced by selenium or carbon tetrachloride.
Topics: Carbon Tetrachloride; Lipotropic Agents; Liver; Liver Diseases; Selenium; Selenium Compounds | 1950 |
Enzyme alterations associated with mouse liver degeneration and regeneration after single carbon tetrachloride feeding.
Topics: Animals; Carbon Tetrachloride; Liver; Liver Diseases; Mice; Regeneration | 1951 |
Extracts of Phellinus linteus grown on germinated brown rice suppress liver damage induced by carbon tetrachloride in rats.
Topics: Animals; Antioxidants; Basidiomycota; Carbon Tetrachloride; Cell Extracts; Chemical and Drug Induced | 2003 |
Hepatoprotective effect of Himoliv, a polyherbal formulation in rats.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Car | 2003 |
Hepatoprotective effect of Epaltes divaricata extract on carbon tetrachloride induced hepatotoxicity in mice.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytoprotection; Drug Evaluati | 2004 |
[Morphology of portal hypertension at the early stage of liver damage induced by CCl4: an experimental study with dogs].
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur | 2004 |
Effect of dimethyl diphenyl bicarboxylate on normal and chemically-injured liver.
Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Antioxidants; Carbon Tetrachloride; Chemical | 2002 |
Intravital staining of damaged liver cells; the use of dyes in the study of necrosis and repair following acute chemical injury.
Topics: Carbon Tetrachloride; Coloring Agents; Liver; Liver Diseases; Necrosis; Staining and Labeling | 1950 |
Activated hepatic stellate cells express keratinocyte growth factor in chronic liver disease.
Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Disease Models, Animal; Fibroblast Growth Factor 7; | 2004 |
Effect of Solanum trilobatum against carbon tetrachloride induced hepatic damage in albino rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Carb | 2004 |
Isolation of ani-hepatotoxic principle form the juice of Ecballium elaterium.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cucurbi | 1999 |
Reevaluation of bone marrow-derived cells as a source for hepatocyte regeneration.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Carbon Tetrachloride; Chemical | 2004 |
Effect of Asteracantha longifolia Nees. against CCl4 induced liver dysfunction in rat.
Topics: Acanthaceae; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; Liver; L | 2005 |
Hepatoprotective properties of Commiphora opobalsamum ("Balessan"), a traditional medicinal plant of Saudi Arabia.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Commiphora; Female; Liver Dis | 2004 |
5-Fluorouracil catabolism to 5-fluoro-5,6-dihydrouracil is reduced by acute liver impairment in mice.
Topics: Animals; Antimetabolites, Antineoplastic; Area Under Curve; Carbon Tetrachloride; Female; Fluorourac | 2005 |
Oleanolic acid nanosuspensions: preparation, in-vitro characterization and enhanced hepatoprotective effect.
Topics: Administration, Oral; Alanine Transaminase; Animals; Calorimetry, Differential Scanning; Carbon Tetr | 2005 |
Hepatoprotective activity of the constituents in Swertia pseudochinensis.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, D | 2005 |
Effects of chicken extract on antioxidative status and liver protection under oxidative stress.
Topics: Alanine Transaminase; Animals; Anserine; Antioxidants; Aspartate Aminotransferases; Body Weight; Car | 2004 |
Comparison of metabolic profiles from serum from hepatotoxin-treated rats by nuclear-magnetic-resonance-spectroscopy-based metabonomic analysis.
Topics: 1-Naphthylisothiocyanate; Administration, Oral; Animals; Carbon Tetrachloride; Chemical and Drug Ind | 2005 |
PGE2 alleviates kidney and liver damage, decreases plasma renin activity and acute phase response in cirrhotic rats with acute liver damage.
Topics: Acute-Phase Proteins; Animals; Blotting, Northern; Carbon Tetrachloride; Chemical and Drug Induced L | 2005 |
Gabexate mesilate, a synthetic protease inhibitor, attenuates carbon tetrachloride-induced liver injury in rats.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Disea | 2005 |
Inhibitory effect on proliferation of vascular smooth muscle cells and protective effect on CCl(4)-induced hepatic damage of HEAI extract.
Topics: Animals; Basidiomycota; Carbon Tetrachloride; Cell Proliferation; Chemical and Drug Induced Liver In | 2005 |
Immunohistochemical distribution of activated nuclear factor kappaB and peroxisome proliferator-activated receptors in carbon tetrachloride-induced chronic liver injury in rats.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chronic Disease; Hepatocytes; | 2005 |
Inhibition of 5-lipoxygenase-activating protein abrogates experimental liver injury: role of Kupffer cells.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Arachidonate 5-Lipoxygenase; Carbon Tetrachloride; Carr | 2005 |
Protective effect of Indigofera oblongifolia in CCl4-induced hepatotoxicity.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Carb | 2005 |
Effective protection of Terminalia catappa L. leaves from damage induced by carbon tetrachloride in liver mitochondria.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Carbon Tetrachloride; Chemical and Drug Induced Live | 2006 |
In vivo antihepatotoxic effects of Ligularia fischeri var. spiciformis and the identification of the active component, 3,4-dicaffeoylquinic acid.
Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransf | 2005 |
Hepatoprotective effects of rubiadin, a major constituent of Rubia cordifolia Linn.
Topics: Alkaline Phosphatase; Animals; Anthraquinones; Antioxidants; Aspartate Aminotransferases; Carbon Tet | 2006 |
Distribution and isoforms of epimorphin in carbon tetrachloride-induced acute liver injury in mice.
Topics: Acute Disease; Alanine Transaminase; Animals; Blotting, Western; Carbon Tetrachloride; Cell Aggregat | 2005 |
Hepatoprotective activity of Beta vulgaris against CCl4-induced hepatic injury in rats.
Topics: Alkaline Phosphatase; Animals; Beta vulgaris; Carbon Tetrachloride; Chemical and Drug Induced Liver | 2006 |
Comparative evaluation of hepatoprotective activity of carotenoids of microalgae.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bacterial Proteins | 2005 |
Protective effect of glycoprotein isolated from Ulmus davidiana Nakai on carbon tetrachloride-induced mouse liver injury.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Catalase; Cell Line; Chemical and Drug Induced Liver In | 2006 |
Bone disorders in experimentally induced liver disease in growing rats.
Topics: Animals; Biomechanical Phenomena; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Carbon Tet | 2005 |
Therapeutic effect of transplanting HGF-treated bone marrow mesenchymal cells into CCl4-injured rats.
Topics: Albumins; alpha-Fetoproteins; Animals; Bone Marrow Cells; Carbon Tetrachloride; Cell Differentiation | 2006 |
Hepatic stellate cells express synemin, a protein bridging intermediate filaments to focal adhesions.
Topics: Animals; Blotting, Western; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver I | 2006 |
Characteristics of rat bone marrow cells differentiated into a liver cell lineage and dynamics of the transplanted cells in the injured liver.
Topics: 2-Acetylaminofluorene; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Carbon Tetrachloride | 2006 |
Hepatoprotective effect of total flavonoids from Laggera alata against carbon tetrachloride-induced injury in primary cultured neonatal rat hepatocytes and in rats with hepatic damage.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Asteraceae; Biphen | 2006 |
In vitro and in vivo protective effects of proteoglycan isolated from mycelia of Ganoderma lucidum on carbon tetrachloride-induced liver injury.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cells, Cultured; C | 2006 |
Hepatoprotective effect of a hot-water extract from the edible thorny oyster Spondylus varius on carbon tetrachloride-induced liver injury in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug | 2006 |
Crotalic and emarginellic acids: two triterpenes from Crotalaria emarginella and anti-inflammatory and anti-hepatotoxic activity of crotalic acid.
Topics: Animals; Anti-Inflammatory Agents; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cro | 2006 |
Hepatoprotective activity of Psidium guajava Linn. leaf extract.
Topics: Acetaminophen; Administration, Oral; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver | 2006 |
Effect of hexane extract of Boswellia serrata oleo-gum resin on chemically induced liver damage.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Boswellia; Carbon Tetrachloride; Chemical and Drug | 2006 |
Induction of Gas6 protein in CCl4-induced rat liver injury and anti-apoptotic effect on hepatic stellate cells.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Cell Survival; Cells, Cultured; Chemical and Drug Induced | 2006 |
Glycoprotein isolated from Ulmus davidiana NAKAI protects against carbon tetrachloride-induced liver injury in the mouse.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Catalase; Cell Survival; Cells, Cultured; Chemi | 2006 |
Evaluation of hybrid liposomes-encapsulated silymarin regarding physical stability and in vivo performance.
Topics: Administration, Buccal; Alanine Transaminase; Amines; Animals; Antioxidants; Aspartate Aminotransfer | 2006 |
Isolation, structure elucidation and in vivo hepatoprotective potential of trans-tetracos-15-enoic acid from Indigofera tinctoria Linn.
Topics: Acetaminophen; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Fatty Acids, M | 2006 |
Protective effects of Zingiber officinale (Zingiberaceae) against carbon tetrachloride and acetaminophen-induced hepatotoxicity in rats.
Topics: Acetaminophen; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dose-Response | 2006 |
Enhanced therapeutic potential of naringenin-phospholipid complex in rats.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Catalase; Chemical and Drug Induced Liver Injury; Chemi | 2006 |
Highly liver-specific heme oxygenase-1 induction by interleukin-11 prevents carbon tetrachloride-induced hepatotoxicity.
Topics: Animals; Blotting, Northern; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dose-Resp | 2006 |
In utero transplantation of human hematopoietic stem/progenitor cells partially repairs injured liver in mice.
Topics: Animals; Animals, Newborn; Antigens, CD34; Bone Marrow; Carbon Tetrachloride; Cell Differentiation; | 2006 |
Hepatic progenitor cells, stem cells, and AFP expression in models of liver injury.
Topics: alpha-Fetoproteins; Animals; Carbon Tetrachloride; Cell Differentiation; Cell Proliferation; Disease | 2006 |
Protection against CCl4-induced injury in liver by adenovirally introduced thioredoxin gene.
Topics: Adenoviridae; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cell | 2006 |
Docosahexaenoic acid (DHA) blunts liver injury by conversion to protective lipid mediators: protectin D1 and 17S-hydroxy-DHA.
Topics: Animals; Carbon Tetrachloride; Cell Line; Chemical and Drug Induced Liver Injury; Diet; Dietary Fats | 2006 |
Sustained activation of Rac1 in hepatic stellate cells promotes liver injury and fibrosis in mice.
Topics: Actins; Animals; Carbon Tetrachloride; Cells, Cultured; Collagen; Cytochrome P-450 CYP2E1; Hepatocyt | 2006 |
Purification and characterization of a 43 kD hepatoprotective protein from the herb Cajanus indicus L.
Topics: Animals; Cajanus; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dose-Response Relati | 2006 |
Syngenic bone marrow cells restore hepatic function in carbon tetrachloride-induced mouse liver injury.
Topics: Actins; Animals; Antigens, CD34; Bone Marrow Cells; Bone Marrow Transplantation; Carbon Tetrachlorid | 2006 |
Peroxisome proliferated-activated receptor gamma ligand, Pioglitazone, does not prevent hepatic fibrosis in mice.
Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver Injury; Extracellula | 2007 |
Assessment of diffusion-weighted MR imaging in liver fibrosis.
Topics: Analysis of Variance; Animals; Carbon Tetrachloride; Diffusion Magnetic Resonance Imaging; Echo-Plan | 2007 |
Preliminary studies on antihepatotoxic effect of Physalis peruviana Linn. (Solanaceae) against carbon tetrachloride induced acute liver injury in rats.
Topics: Animals; Antioxidants; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dis | 2007 |
Protein isolate from the herb, Phyllanthus niruri L. (Euphorbiaceae), plays hepatoprotective role against carbon tetrachloride induced liver damage via its antioxidant properties.
Topics: Animals; Antioxidants; Biological Assay; Carbon Tetrachloride; Catalase; Glutathione; Injections, In | 2007 |
Hepatoprotection of tea seed oil (Camellia oleifera Abel.) against CCl4-induced oxidative damage in rats.
Topics: Animals; Antioxidants; Camellia; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and | 2007 |
Protective effect of salvianic acid a on acute liver injury induced by carbon tetrachloride in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Caffeic Acids; Carbon Tetr | 2007 |
Prevention of hepatic oxidative injury by Xiao-Chen-Chi-Tang in mice.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Cath | 2007 |
Effects of salvianolic acid a on oxidative stress and liver injury induced by carbon tetrachloride in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Caffeic Acids; Carbon Tetr | 2007 |
The effect of oculo-acupuncture on acute hepatic injury induced by carbon tetrachloride in dogs.
Topics: Acupuncture Points; Acupuncture Therapy; Alanine Transaminase; Animals; Aspartate Aminotransferases; | 2007 |
Antioxidant and hepatoprotective effects of Orthosiphon stamineus Benth. standardized extract.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Chem | 2007 |
[Cystic degeneration in liver injury induced by CCl4 in SD rats].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cysts; Disease Models, Animal | 2006 |
Hepatoprotective potential of Aloe barbadensis Mill. against carbon tetrachloride induced hepatotoxicity.
Topics: Administration, Oral; Aloe; Animals; Antioxidants; Carbon Tetrachloride; Disease Models, Animal; Dos | 2007 |
Bakuchiol-induced caspase-3-dependent apoptosis occurs through c-Jun NH2-terminal kinase-mediated mitochondrial translocation of Bax in rat liver myofibroblasts.
Topics: Actins; Animals; Apoptosis; bcl-2-Associated X Protein; Carbon Tetrachloride; Caspase 3; Cells, Cult | 2007 |
Hepatoprotective effect of a protein-enriched fraction from the maggots (Musca domestica) against CCl4-induced hepatic damage in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug | 2007 |
Simvastatin treatment improves liver sinusoidal endothelial dysfunction in CCl4 cirrhotic rats.
Topics: Animals; Anticholesteremic Agents; Carbon Tetrachloride; Cyclic GMP; Liver; Liver Cirrhosis; Liver D | 2007 |
Recombinant ST2 boosts hepatic Th2 response in vivo.
Topics: Animals; Carbon Tetrachloride; CD4-Positive T-Lymphocytes; Cytokines; Fibrosis; Immunoglobulin Fc Fr | 2007 |
[Committed differentiation of transplanted bone derived mesenchymal stem cells and their potential to amend damaged liver functions: in vivo experiment with mice].
Topics: Animals; Carbon Tetrachloride; Cell Differentiation; Cell Transdifferentiation; Cells, Cultured; Che | 2007 |
Effects of Picrorrhiza rhizoma water extracts on the subacute liver damages induced by carbon tetrachloride.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Carbon Tetrachloride; Chemi | 2007 |
Hepatoprotective effect of the ethyl acetate extract of Teucrium polium L. against carbontetrachloride-induced hepatic injury in rats.
Topics: Acetates; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; Free Radica | 2007 |
[Protective effect of Yigan Fuzheng Paidu capsules combined with ozone on CCl4-induced acute hepatic injury in dogs].
Topics: Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Bilirubin; Blood Urea Nitrogen; | 2007 |
[Human umbilical cord blood-derived mononuclear cells repopulate injured mouse liver].
Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Cell Transplantation; Cells, Cultured; Female; Fe | 2007 |
Evaluation of hepatoprotective activity of Clerodendrum serratum L.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Clerodendrum; Cytoprotection; | 2007 |
Hepatoprotective and antioxidant effects of the coffee diterpenes kahweol and cafestol on carbon tetrachloride-induced liver damage in mice.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-45 | 2007 |
Protective role of genistein in acute liver damage induced by carbon tetrachloride.
Topics: Acute Disease; Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; | 2007 |
Stronger Neo-Minophagen C, a glycyrrhizin-containing preparation, protects liver against carbon tetrachloride-induced oxidative stress in transgenic mice expressing the hepatitis C virus polyprotein.
Topics: Alanine Transaminase; Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver I | 2007 |
Protective effect of some tropical vegetables against CCl4-induced hepatic damage.
Topics: Alanine Transaminase; Amaranthus; Animals; Aspartate Aminotransferases; Blood Proteins; Carbon Tetra | 2007 |
Preventive effect of D-002, a mixture of long-chain alcohols from beeswax, on the liver damage induced with CCl4 in rats.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Fatty Alcohols; | 2007 |
[The tracking of allogenic grafted rat bone marrow stem cells in rat liver and their role on repairing injured liver].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bone Marrow Transplantation; Carbon Tetr | 2007 |
Hepatoprotective effect of leaf extracts of Andrographis lineata nees on liver damage caused by carbon tetrachloride in rats.
Topics: Alkaline Phosphatase; Andrographis; Animals; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachl | 2008 |
Calotropis procera latex affords protection against carbon tetrachloride induced hepatotoxicity in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Calotropis; Carbon Tetrachloride; Catala | 2007 |
Protective effect of Aquilegia vulgaris (L.) on carbon tetrachloride-induced oxidative stress in rats.
Topics: Animals; Aquilegia; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Ether; Free Radica | 2007 |
Hepatic viscoelastic parameters measured with MR elastography: correlations with quantitative analysis of liver fibrosis in the rat.
Topics: Animals; Automation; Carbon Tetrachloride; Elasticity; Elasticity Imaging Techniques; Fibrosis; Hydr | 2007 |
Screening of hepatoprotective effect of a herbal mixture against CCl4 induced hepatotoxicity in Swiss albino mice.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Blood Glucose; Blo | 2007 |
Radical scavenging activity of Trianthema triquetra in male albino rats intoxicated with CCl4.
Topics: Aizoaceae; Animals; Ascorbic Acid; Carbon Tetrachloride; Catalase; Chemical and Drug Induced Liver I | 2007 |
Characterization and protection on acute liver injury of a polysaccharide MP-I from Mytilus coruscus.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Glucans; Liver; | 2008 |
Antioxidant and hepatoprotective activity of ethanolic and aqueous extracts of Momordica dioica Roxb. leaves.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Bili | 2008 |
Protective effects of puerarin on carbon tetrachloride-induced hepatotoxicity.
Topics: Alanine Transaminase; Aniline Compounds; Animals; Aspartate Aminotransferases; Biotransformation; Ca | 2007 |
Transgene expression of human PON1 Q in mice protected the liver against CCl4-induced injury.
Topics: Alanine Transaminase; Animals; Aryldialkylphosphatase; Aspartate Aminotransferases; Carbon Tetrachlo | 2008 |
Protective effect of vitamin B12 upon hepatic injury produced by carbon tetrachloride.
Topics: Adrenal Glands; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Corrinoids; Liver Diseases; Ti | 1949 |
Long-term treatment with a Yang-invigorating Chinese herbal formula produces generalized tissue protection against oxidative damage in rats.
Topics: Animals; Carbon Tetrachloride; Carnosine; Chemical and Drug Induced Liver Injury; Cholecalciferol; C | 2008 |
Protective effect of baicalin against carbon tetrachloride-induced acute hepatic injury in mice.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooxygenase | 2008 |
Effects of flavonoids on sphingolipid turnover in the toxin-damaged liver and liver cells.
Topics: Animals; Carbon Tetrachloride; Cell Death; Ceramides; Chemical and Drug Induced Liver Injury; Ethano | 2008 |
Disruption of the Smad7 gene enhances CCI4-dependent liver damage and fibrogenesis in mice.
Topics: Actins; Animals; Apoptosis; Carbon Tetrachloride; Collagen; Disease Models, Animal; Fibrosis; Genes, | 2008 |
Vinpocetine ameliorates acute hepatic damage caused by administration of carbon tetrachloride in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Analysis of Variance; Animals; Aspartate Aminotransferas | 2007 |
Superiority of serum type-I arginase and ornithine carbamyltransferase in the detection of toxicant-induced acute hepatic injury in rats.
Topics: Alanine Transaminase; Animals; Arginase; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical | 2008 |
[Effect of Danxiongfang and its components on experimental liver injury models induced by CCl4 in mice].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug | 2007 |
Posttranslational activation of endothelial nitric oxide synthase attenuates carbon tetrachloride-induced hepatotoxicity in newborn rats.
Topics: Age Factors; Androstadienes; Animals; Animals, Newborn; Carbon Tetrachloride; Cytoprotection; Diseas | 2008 |
Liver protective effects of Morinda citrifolia (Noni).
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug | 2008 |
Hepatoprotective phytocompounds from Cryptomeria japonica are potent modulators of inflammatory mediators.
Topics: Animals; Carbon Tetrachloride; Cell Line; Chemical and Drug Induced Liver Injury; Cryptomeria; Cyclo | 2008 |
Intake of purple grape juice as a hepatoprotective agent in Wistar rats.
Topics: Animals; Anthocyanins; Antioxidants; Beverages; Carbon Tetrachloride; Catalase; Chemical and Drug In | 2008 |
Reduced liver injury in the interleukin-6 knockout mice by chronic carbon tetrachloride administration.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Gene Expression Re | 2008 |
Critical role of CD44 in hepatotoxin-mediated liver injury.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chemokine CXCL2; H | 2008 |
Effects of silymarin on the resolution of liver fibrosis induced by carbon tetrachloride in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug | 2008 |
Antioxidant activity of vinegar produced from distilled residues of the Japanese liquor shochu.
Topics: Acetic Acid; Alcoholic Beverages; Animals; Antioxidants; Carbon Tetrachloride; Carcinoma, Hepatocell | 2008 |
Protective effect of caffeic acid phenethyl ester against carbon tetrachloride-induced hepatotoxicity in mice.
Topics: Animals; Caffeic Acids; Carbon Tetrachloride; Caspase 3; Caspase 8; Catalase; Chemical and Drug Indu | 2008 |
Walnut polyphenols prevent liver damage induced by carbon tetrachloride and d-galactosamine: hepatoprotective hydrolyzable tannins in the kernel pellicles of walnut.
Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver Injury; Flavonoids; | 2008 |
[Studies of liver and bile duct functions. 3. 131-I-rose bengal test of experimental liver disorders in rabbits].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Iodine Radioisoto | 1967 |
Evaluation of phenyl acetate esterase activity as an index of liver damage.
Topics: Animals; Carbon Tetrachloride; Cholinesterases; Clinical Enzyme Tests; Electrophoresis; Esterases; E | 1967 |
[Experimental study on the significance of rheumatic serum reaction in liver diseases--serological observation of the rabbit administered with carbon tetrachloride].
Topics: Animals; Antibody Formation; Antigens; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; | 1967 |
[Lipoprotein biosynthesis in the liver in various conditions].
Topics: Animals; Carbon Isotopes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; In Vitro Tec | 1967 |
Serum gamma-glutamyl transpeptidase activity in healthy cats and cats with induced hepatic disease.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Carbon Tetrachloride; Cat Diseases; Cats; Chemi | 1983 |
Effect of cortisone on the behavior of serotonin, 5-hydroxy-indoloacetic acid and monoaminooxidase in the liver tissue, the blood and the urine in experimental rabbit liver injury with CCl4.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cortisone; Hydroxyindoleaceti | 1982 |
Nuclear magnetic resonance imaging of experimentally induced liver disease.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Ethionine; Humans; Iron; Iron | 1983 |
Chlordecone-induced potentiation of carbon tetrachloride hepatotoxicity: a light and electron microscopic study.
Topics: Animals; Carbon Tetrachloride; Cell Nucleus; Chemical and Drug Induced Liver Injury; Chlordecone; Cy | 1983 |
Chlordecone-induced potentiation of carbon tetrachloride hepatotoxicity: a morphometric and biochemical study.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cell Nucleus; Chem | 1983 |
Carbon tetrachloride-induced liver injury in the rabbit.
Topics: Animals; Arachidonic Acids; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome | 1983 |
[Effects of cianidanol (KB-53) on experimental liver injury in mice--histopathological, histochemical and enzyme-histochemical studies].
Topics: 1-Naphthylisothiocyanate; Alkaline Phosphatase; Animals; Benzopyrans; Carbon Tetrachloride; Catechin | 1983 |
Effects of medroxyprogesterone acetate on hepatic glucose metabolism and microsomal enzyme activity in rats with normal and altered liver.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Syste | 1984 |
Experimental studies on nutrition management in liver injury.
Topics: Alanine Transaminase; Amino Acids, Branched-Chain; Animals; Carbon Tetrachloride; Enteral Nutrition; | 1983 |
Effect of realimentation after several days' pure carbohydrate intake on DNA synthesis in regenerating rat liver.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Diet; Dietary Carbohydrates; | 1980 |
Studies on the mechanism of glutathione prevention of carbon tetrachloride-induced liver injury.
Topics: Animals; Arachidonic Acids; Body Temperature; Carbon Tetrachloride; Chemical and Drug Induced Liver | 1983 |
Strain differences in mice in carbon tetrachloride-induced liver injury.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; Glycocholic Acid; Liv | 1983 |
An improved method of determination of SH group concentration and reactivity in plasma of patients with various clinical disorders and in rats after administration of indomethacin or carbon tetrachloride.
Topics: Animals; Arthritis, Rheumatoid; Carbon Tetrachloride; Humans; Indomethacin; Liver Diseases; Male; Ra | 1983 |
Genetics of carbon tetrachloride-induced liver injury in mice. II. Multigenic regulation.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; Genotype; Glycocholic | 1984 |
Late preventive effects of phenylmethylsulfonyl-fluoride on carbon tetrachloride-induced liver necrosis.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur | 1984 |
[Studies on comprehensive evaluation of toxic liver injury (author's transl)].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Hematolo | 1981 |
Biliary excretion of antibiotics in rats.
Topics: Animals; Anti-Bacterial Agents; Bile; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; | 1983 |
The protective effect of tinoridine against carbon tetrachloride hepatotoxicity.
Topics: Animals; Anti-Inflammatory Agents; Biotransformation; Carbon Tetrachloride; Carbon Tetrachloride Poi | 1980 |
Sensitivity of serum glutamic oxaloacetic transaminase and bile acid levels for the detection of experimental liver injury in rats.
Topics: Animals; Aspartate Aminotransferases; Bile Acids and Salts; Carbon Tetrachloride; Chemical and Drug | 1981 |
Cell-mediated immunity to liver antigen in toxic liver injury. II. Role in pathogenesis of liver damage.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Immunity, Cellular; Liver; Li | 1980 |
[Changes in the anti-heparin activity of platelet-free plasma in rats with induced inflammation and after administration of CC14 (author's transl)].
Topics: Animals; Blood Coagulation Factors; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; In | 1982 |
Hepatotoxicity of trichloroethylene-carbon tetrachloride mixtures in rats. A possible consequence of the potentiation by trichloroethylene of carbon tetrachloride-induced lipid peroxidation and liver lesions.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Glutathione; Lipid Metabolism | 1982 |
[Effect of exogenous RNA on the regenerating activity of the liver after partial hepatectomy and after damage of the hepatic tissue by tetrachloromethane].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Hepatectomy; Liver Diseases; | 1982 |
The differential localization of various drug metabolizing systems within the rat liver lobule as determined by the hepatotoxins allyl alcohol, carbon tetrachloride and bromobenzene.
Topics: 1-Propanol; Animals; Bromobenzenes; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Liver; Liv | 1981 |
Variations of plasma enzymes in the pony and the dog after carbon tetrachloride administration.
Topics: Alkaline Phosphatase; Animals; Arginase; Bilirubin; Carbon Tetrachloride; Dog Diseases; Dogs; Female | 1981 |
The effect of dibutyl sulphide on hepatocytes studied by means of the isolated rat liver perfusion after preceding exposure to tetrachloromethane and phenobarbital in vivo.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Liver; Liver Diseases; Perfus | 1981 |
Attachment to collagen by isolated hepatocytes from rats with induced hepatic fibrosis.
Topics: Animals; Carbon Tetrachloride; Cell Adhesion; Chemical and Drug Induced Liver Injury; Collagen; Live | 1980 |
Serum bile acid concentration in some experimental liver lesions of rat.
Topics: Alanine Transaminase; Aniline Compounds; Animals; Bile Acids and Salts; Bile Ducts; Carbon Tetrachlo | 1980 |
Cell-mediated immunity to liver antigen in toxic liver injury. I. Occurrence and specificity.
Topics: Animals; Antigens; Carbon Tetrachloride; Cell Migration Inhibition; Chemical and Drug Induced Liver | 1980 |
Pyrazole prevention of CC14-induced ultrastructural changes in rat liver.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum; Glutat | 1980 |
Impaired glucose uptake and intact gluconeogenesis in perfused rat liver after carbon tetrachloride injury.
Topics: Animals; Blood Glucose; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Gluconeogenesi | 1995 |
Evaluation of the protective potential of Artemisia maritima extract on acetaminophen- and CCl4-induced liver damage.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Liv | 1995 |
Preventive and curative effects of Artemisia absinthium on acetaminophen and CCl4-induced hepatotoxicity.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Che | 1995 |
[Evaluation of hepatic blood flow using 99mTc-GSA in rats with hepatic blood flow manipulation].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Hepatic Artery; Ligation; Liv | 1995 |
Preventive effect of dai-saiko-to (da-chai-hu-tang) extract on disrupted hepatic active oxygen metabolism in rats with carbon tetrachloride-induced liver injury.
Topics: Administration, Oral; Alanine Transaminase; Animals; Aspartic Acid; Carbon Tetrachloride; Chemical a | 1995 |
[Protective effects of the stem of Berchemia racemosa Sieb. et Zucc. on experimental liver injuries].
Topics: 1-Naphthylisothiocyanate; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cho | 1995 |
Vitamin A modulation of xenobiotic-induced hepatotoxicity in rodents.
Topics: Alanine Transaminase; Animals; Body Weight; Carbon Tetrachloride; Chemical and Drug Induced Liver In | 1994 |
Accumulation and cellular localization of fibrinogen/fibrin during short-term and long-term rat liver injury.
Topics: Animals; Blotting, Northern; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; F | 1995 |
Use of prostaglandin I2 analog in treatment of massive hepatic necrosis associated with endothelial cell injury and diffuse sinusoidal fibrin deposition.
Topics: Animals; Antithrombin III; Capillaries; Carbon Tetrachloride; Cells, Cultured; Dimethylnitrosamine; | 1995 |
In vivo correlation between liver and blood energy status as evidenced by chronic treatment of carbon tetrachloride and adenosine to rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood; C | 1994 |
Hepatoprotective effect of BPC 157, a 15-amino acid peptide, on liver lesions induced by either restraint stress or bile duct and hepatic artery ligation or CCl4 administration. A comparative study with dopamine agonists and somatostatin.
Topics: Amino Acid Sequence; Animals; Bile Ducts; Carbon Tetrachloride; Chemical and Drug Induced Liver Inju | 1993 |
Effect of ursodeoxycholic acid on in vivo and in vitro toxic liver injury in rats.
Topics: Acetaminophen; Administration, Oral; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Car | 1994 |
The effect of Chinese hepatoprotective medicines on experimental liver injury in mice.
Topics: 1-Propanol; Acetaminophen; Animals; Cadmium; Carbon Tetrachloride; Chemical and Drug Induced Liver I | 1994 |
In vivo magnetic resonance imaging study of Kupffer cell involvement in CCl4-induced hepatotoxicity in rats.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Edema; Kupffer Cells; Liver D | 1994 |
Protection of carbon tetrachloride hepatotoxicity by cinchona alkaloids.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile; Carbon Tetrachloride; Chemical and | 1994 |
Effects of liver damage induced by carbon tetrachloride on glutathione and glutathione-dependent enzymes in rat gastric mucosa.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; gamma-Glutamyltransferase; Ga | 1993 |
Effect of hepatotoxic doses of paracetamol and carbon tetrachloride on the serum and hepatic carboxylesterase activity in mice.
Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Biomarkers; Carbon Tetrachloride; Carboxylic Es | 1993 |
Cytoprotective effect of prostaglandin E2 and I2 in experimental liver damage.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dinoprostone; Epoprostenol; L | 1994 |
Protective effects of sesamin against liver damage caused by alcohol or carbon tetrachloride in rodents.
Topics: Administration, Inhalation; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetra | 1993 |
Late preventive effects of quinacrine on carbon tetrachloride induced liver necrosis.
Topics: Animals; Body Temperature; Calcium; Carbon Radioisotopes; Carbon Tetrachloride; Chemical and Drug In | 1993 |
Effect of antimitotic agent colchicine on carbon tetrachloride toxicity.
Topics: Alanine Transaminase; Animals; Antineoplastic Agents; Aspartate Aminotransferases; Biotransformation | 1993 |
Ca-efflux, from direct membrane injury by CCl4, is elicited by amphiphilic vehicles in vitro.
Topics: Animals; Calcium; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Electron Spin Resona | 1993 |
Monocyte chemoattractant protein 1 (MCP-1) expression occurs in toxic rat liver injury and human liver disease.
Topics: Animals; Carbon Tetrachloride; Chemokine CCL2; Chemotactic Factors; Cytokines; Galactosamine; Gene E | 1994 |
Granuloma formation in the liver of Balb/c mice intoxicated with carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Desmin; Granuloma; Immunoenzy | 1993 |
Pharmacokinetics of indocyanine green in rats with experimentally induced hepatic diseases.
Topics: Acute Disease; Animals; Bile; Blood Proteins; Carbon Tetrachloride; Chemical and Drug Induced Liver | 1993 |
Antihepatotoxic activity of phenolic flavan-3-ols and their derivatives.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug | 1993 |
Pharmacological and pathological studies on Taiwan folk medicine (IX): The hepatoprotective effect of the methanolic extract from echinops grijisii.
Topics: 1-Butanol; Acetates; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biopsy; Butanols; C | 1993 |
Evaluation of the anti-inflammatory and liver-protective effects of anoectochilus formosanus, ganoderma lucidum and gynostemma pentaphyllum in rats.
Topics: Alanine Transaminase; Alkaloids; Animals; Aspartate Aminotransferases; Biopsy; Carbon Tetrachloride; | 1993 |
Protective effects of tetrahydroneopterin against free radical-induced injury.
Topics: Animals; Biopterins; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Doxorubicin; Edem | 1993 |
Role of lipid peroxidation in acetaminophen-induced hepatotoxicity: comparison with carbon tetrachloride.
Topics: Acetaminophen; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Drug Interacti | 1993 |
Determination of 4-hydroxynonenal by high-performance liquid chromatography with electrochemical detection.
Topics: Aldehydes; Animals; Bromobenzenes; Bromotrichloromethane; Carbon Tetrachloride; Cell Line; Chemical | 1993 |
Quantitation of hydroperoxy-eicosatetraenoic acids and hydroxy-eicosatetraenoic acids as indicators of lipid peroxidation using gas chromatography-mass spectrometry.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Brain; Carbon Tetrachloride; Chemical and Dr | 1993 |
Combined effects of streptozotocin-induced diabetes plus 4-methylpyrazole treatment on rat liver cytochrome P4502E1.
Topics: Animals; Carbon Tetrachloride; Catalysis; Chemical and Drug Induced Liver Injury; Cytochrome P-450 C | 1993 |
Characterization of vitamin A potentiation of carbon tetrachloride-induced liver injury.
Topics: 1-Propanol; Acetaminophen; Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug In | 1993 |
Vitamin A potentiation of carbon tetrachloride hepatotoxicity: enhanced lipid peroxidation without enhanced biotransformation.
Topics: Animals; Biotransformation; Carbon Radioisotopes; Carbon Tetrachloride; Chemical and Drug Induced Li | 1993 |
Vitamin A potentiation of carbon tetrachloride hepatotoxicity: role of liver macrophages and active oxygen species.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Catalase; Chemical and Drug Induced Liver Injur | 1993 |
Effect of hepatoprotective ayurvedic drugs on lipolytic activities during CCl4 induced acute hepatic injury in albino rats.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; India; Lipase; Liver; Liver D | 1993 |
Elevation of cystathionine gamma-lyase activity in the serum of rats treated with a single dose of carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cystathionine gamma-Lyase; Li | 1995 |
Late protective effects of the anticalmodulin drug fluphenazine on carbon tetrachloride-induced liver necrosis.
Topics: Animals; Body Temperature Regulation; Calmodulin; Carbon Tetrachloride; Chemical and Drug Induced Li | 1995 |
Modulation of chemical-induced lung and liver toxicity by all-trans-retinol in the male Sprague-Dawley rat.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Drug Synergism; Gadolinium; L | 1995 |
Enhanced effectiveness of dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate in combination with garlic oil against experimental hepatic injury in rats and mice.
Topics: 1-Propanol; Administration, Oral; Allyl Compounds; Animals; Antioxidants; Carbon Tetrachloride; Cell | 1995 |
Expression of heparin-binding EGF-like growth factor in rat liver injured by carbon tetrachloride or D-galactosamine.
Topics: Animals; Blotting, Western; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Epidermal | 1996 |
Protective effect of rifampicin against acute liver injury induced by carbon tetrachloride in mice.
Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Lip | 1995 |
The nature and significance of liver cell vacuolation following hepatocellular injury--an analysis based on observations on rats rendered tolerant to hepatotoxic damage.
Topics: Adaptation, Physiological; Aflatoxin B1; Alanine Transaminase; Animals; Aspartate Aminotransferases; | 1996 |
Methanol potentiation of carbon tetrachloride hepatotoxicity: the central role of cytochrome P450.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Syste | 1996 |
Protective effect of celosian, an acidic polysaccharide, on chemically and immunologically induced liver injuries.
Topics: Animals; Bilirubin; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Enzymes; Galactosa | 1996 |
Prolonged decrease in hepatic connexin32 in chronic liver injury induced by carbon tetrachloride in rats.
Topics: Alanine Transaminase; Animals; Blotting, Northern; Carbon Tetrachloride; Cell Division; Chemical and | 1996 |
Changes in taurine as an indicator of hepatic dysfunction and biochemical perturbations. Studies in vivo and in vitro.
Topics: Animals; Biomarkers; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cells, Cultured; Clenbute | 1996 |
[Expression and significance of PKC alpha in regenerating liver of rats after partial hepatectomy and CCl4 administration].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Hepatectomy; Immunohistochemi | 1996 |
Radioprotectors as late preventive agents against carbon tetrachloride induced liver necrosis: protection by 2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721).
Topics: Alkaline Phosphatase; Amifostine; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Inj | 1995 |
Further evidence for zinc as a hepatoprotective agent in rat liver toxicity.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Glutathione; Lipid Peroxidati | 1995 |
Cholesteryl hemisuccinate treatment protects rodents from the toxic effects of acetaminophen, adriamycin, carbon tetrachloride, chloroform and galactosamine.
Topics: Acetaminophen; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Ch | 1997 |
Effect of Emulphor, an emulsifier, on the pharmacokinetics and hepatotoxicity of oral carbon tetrachloride in the rat.
Topics: Administration, Oral; Alanine Transaminase; Animals; Area Under Curve; Carbon Tetrachloride; Chemica | 1997 |
Pre- and postprandial total serum bile acid concentration following acute liver damage in dogs.
Topics: Acute Disease; Animals; Bile Acids and Salts; Carbon Tetrachloride; Chemical and Drug Induced Liver | 1997 |
Potent antihepatotoxic activity of dicaffeoyl quinic acids from propolis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cells, Cultured; C | 1996 |
Prostanoids and free radicals in Cl4C-induced hepatotoxicity in rats: effect of astilbin.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced | 1997 |
Synthesis of monoesters of pyrroloquinoline quinone and imidazopyrroloquinoline, and radical scavenging activities using electron spin resonance in vitro and pharmacological activity in vivo.
Topics: Administration, Oral; Animals; Biological Assay; Carbon Tetrachloride; Cataract; Chemical and Drug I | 1997 |
Preventive effect of oren-gedoku-to (huanglian-jie-du-tang) extract on progression of carbon tetrachloride-induced acute liver injury in rats.
Topics: Administration, Oral; Alanine Transaminase; Animals; Anti-Ulcer Agents; Aspartate Aminotransferases; | 1997 |
Protective effect of Rhinax, a herbal formulation, against CCl4-induced liver injury and survival in rats.
Topics: Administration, Oral; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cytochrome P-450 E | 1997 |
Abnormal expressions of hepatocellular proteins and extracellular matrix in CCL4-induced liver injury in rats.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Extracellular Matr | 1996 |
alpha-Tocopheryl hemisuccinate administration increases rat liver subcellular alpha-tocopherol levels and protects against carbon tetrachloride-induced hepatotoxicity.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochr | 1997 |
The effect of aflatoxin B1 on the expression of early response genes and transforming growth factor-alpha in CCl4 induced rat liver injury.
Topics: Aflatoxin B1; Animals; Carbon Tetrachloride; Carcinogens; Chemical and Drug Induced Liver Injury; Ge | 1997 |
Hepatic ultrasonographic findings in experimental carbon tetrachloride intoxication of the dog.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biopsy; Carbon Tetrachloride; Chemical a | 1997 |
Gene expression in liver after toxic injury: analysis of heat shock response and oxidative stress-inducible genes.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA-Binding Proteins; Ferriti | 1997 |
Alterations in susceptibility to carbon tetrachloride toxicity and hepatic antioxidant/detoxification system in streptozotocin-induced short-term diabetic rats: effects of insulin and Schisandrin B treatment.
Topics: Alanine Transaminase; Animals; Antioxidants; Blood Glucose; Carbon Tetrachloride; Chemical and Drug | 1997 |
Zeaxanthin dipalmitate from Lycium chinense has hepatoprotective activity.
Topics: Animals; beta Carotene; Carbon Tetrachloride; Cell Division; Cells, Cultured; Chemical and Drug Indu | 1997 |
A microcholangiographic study of liver disease models in rats.
Topics: 1-Naphthylisothiocyanate; Animals; Bile Duct Diseases; Bile Ducts; Carbon Tetrachloride; Cell Divisi | 1995 |
Esculetin prevents liver damage induced by paracetamol and CCL4.
Topics: Acetaminophen; Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; | 1998 |
Green tea suppresses D-galactosamine-induced liver injury in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug | 1998 |
Gamma-glutamylcysteinylethyl ester attenuates progression of carbon tetrachloride-induced acute liver injury in mice.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur | 1998 |
Deficient liver regeneration after carbon tetrachloride injury in mice lacking type 1 but not type 2 tumor necrosis factor receptor.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA; DN | 1998 |
The recovering effect of betaine on carbon tetrachloride-induced liver injury.
Topics: Alanine Transaminase; Animals; Betaine; Carbon Tetrachloride; Cell Nucleus; Chemical and Drug Induce | 1998 |
Hepatoprotective effect of C-phycocyanin: protection for carbon tetrachloride and R-(+)-pulegone-mediated hepatotoxicty in rats.
Topics: Alanine Transaminase; Aminopyrine N-Demethylase; Animals; Carbon Tetrachloride; Chemical and Drug In | 1998 |
Colchicine antimitosis abolishes resiliency of postnatally developing rats to chlordecone-amplified carbon tetrachloride hepatotoxicity and lethality.
Topics: Animals; Carbon Tetrachloride; Cell Division; Chemical and Drug Induced Liver Injury; Chlordecone; C | 1998 |
Nitric oxide protection of rat liver from lipid peroxidation, collagen accumulation, and liver damage induced by carbon tetrachloride.
Topics: Animals; Arginine; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagen; Drug Inte | 1998 |
Use of 99mTc-mercaptoacetyltriglycine (MAG3)-biocytin hepatobiliary scintigraphy to study the protective effect of a synthetic enzyme inhibitor on acute hepatotoxicity in mice.
Topics: Animals; Biliary Tract; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-4 | 1998 |
Betaine reduces hepatic lipidosis induced by carbon tetrachloride in Sprague-Dawley rats.
Topics: Administration, Oral; Animals; Betaine; Body Weight; Carbon Tetrachloride; Chemical and Drug Induced | 1998 |
Effect of pretreatment of rats with an urinary preparation on liver injuries induced by carbon tetrachloride and alpha-naphthylisothiocyanate.
Topics: 1-Naphthylisothiocyanate; Acute Disease; Animals; Carbon Tetrachloride; Chemical and Drug Induced Li | 1998 |
Resistance to carbon tetrachloride-induced hepatotoxicity in mice which lack CYP2E1 expression.
Topics: Animals; Body Weight; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induce | 1998 |
TA1 oncofetal rat liver cDNA and putative amino acid permease: temporal correlation with c-myc during acute CCl4 liver injury and variation of RNA levels in response to amino acids in hepatocyte cultures.
Topics: Amino Acid Transport Systems; Amino Acids; Animals; Carbon Tetrachloride; Cell Survival; Cells, Cult | 1999 |
Endogenous glucocorticoids released during acute toxic liver injury enhance hepatic IL-10 synthesis and release.
Topics: Acute Disease; Adrenalectomy; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; | 1999 |
Effect of central corticotropin-releasing factor on carbon tetrachloride-induced acute liver injury in rats.
Topics: Acute Disease; Animals; Atropine; Brain; Carbon Tetrachloride; Chemical and Drug Induced Liver Injur | 1999 |
Effects of Corylus avellana in acetaminophen and CCl4 induced toxicosis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Carbon Tetrachloride; Chemical and Drug Induced Li | 1999 |
Inhibition of cytochrome P450 2E1 expression by oleanolic acid: hepatoprotective effects against carbon tetrachloride-induced hepatic injury.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochr | 1999 |
Nitric oxide increases hepatic arterial blood flow in rats with carbon tetrachloride-induced acute hepatic injury.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Enzyme Inhibit | 1999 |
Free-radical scavenging action of medicinal herbs from Ghana: Thonningia sanguinea on experimentally-induced liver injuries.
Topics: Alanine Transaminase; Aniline Hydroxylase; Animals; Antioxidants; Aspartate Aminotransferases; Bepri | 1999 |
The protective action of thymol against carbon tetrachloride hepatotoxicity in mice.
Topics: Alanine Transaminase; Animals; Anti-Infective Agents; Antioxidants; Butylated Hydroxytoluene; Carbon | 1999 |
Astilbin selectively induces dysfunction of liver-infiltrating cells--novel protection from liver damage.
Topics: Animals; Antioxidants; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA | 1999 |
Effects of dietary polyunsaturated fatty acids and nucleotides on tissue fatty acid profiles of rats with carbon tetrachloride-induced liver damage.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dietary Fats; Fatty Acids; Li | 1999 |
Evaluation of hepatoprotective activity of Cassia fistula leaf extract.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Carbon | 1999 |
Susceptibility to chlordecone-carbon tetrachloride induced hepatotoxicity and lethality is both age and sex dependent.
Topics: Age Factors; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemi | 1999 |
Extracellular signal-regulated kinase activation differentially regulates platelet-derived growth factor's actions in hepatic stellate cells, and is induced by in vivo liver injury in the rat.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbon Tetrachloride; Cell Division; Cell Mov | 1999 |
Protective effects of vitamin E on carbon tetrachloride-induced liver damage in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Carbon | 1999 |
Evaluation of the protective effects of Schisandra chinensis on Phase I drug metabolism using a CCl4 intoxication model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Area Under Curve; Carbon Tetrachloride | 1999 |
Low-dose gamma-ray irradiation reduces oxidative damage induced by CCl4 in mouse liver.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug | 1999 |
Differential regulation of activin A for hepatocyte growth and fibronectin synthesis in rat liver injury.
Topics: Activin Receptors; Activins; Animals; Carbon Tetrachloride; Cell Division; Chemical and Drug Induced | 2000 |
Rifampicin suppresses hepatic CYP2E1 expression and minimizes DNA injury caused by carbon tetrachloride in perivenular hepatocytes of mice.
Topics: Animals; Blotting, Western; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome | 2000 |
Protective effect of curcumin in rat liver injury induced by carbon tetrachloride.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; | 2000 |
Interaction of albumin mRNA with proteins from rat liver with CCl(4)-induced injury.
Topics: Acute-Phase Reaction; Albumins; Amanitins; Animals; Base Sequence; Binding, Competitive; Carbon Tetr | 2000 |
Platelet-endothelial cell adhesion molecule-1 gene expression in liver sinusoidal endothelial cells during liver injury and repair.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Endothelium, Vascular; Gene E | 2000 |
Endotoxin pretreatment protects against the hepatotoxicity of acetaminophen and carbon tetrachloride: role of cytochrome P450 suppression.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Carbon Tetrachloride; Chemic | 2000 |
Yang-Gan-Wan protects mice against experimental liver damage.
Topics: Acetaminophen; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models | 2000 |
Hepatoprotective effects of Arctium lappa on carbon tetrachloride- and acetaminophen-induced liver damage.
Topics: Acetaminophen; Animals; Antioxidants; Asteraceae; Carbon Tetrachloride; Chemical and Drug Induced Li | 2000 |
Hepatoprotective effects of Turkish folk remedies on experimental liver injury.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Carbon Tetrachlori | 2000 |
The evaluation of the therapeutic effect of tao-shang-tsao on alpha-naphthylisothiocyanate and carbon tetrachloride-induced acute liver damage in rats.
Topics: 1-Naphthylisothiocyanate; Animals; Carbon Tetrachloride; Cholangitis; Drugs, Chinese Herbal; Hyperbi | 2000 |
Metallothionein expression protects against carbon tetrachloride-induced hepatotoxicity, but overexpression and dietary zinc supplementation provide no further protection in metallothionein transgenic and knockout mice.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dietary | 2001 |
Ampelopsis brevipedunculata (Vitaceae) extract inhibits a progression of carbon tetrachloride-induced hepatic injury in the mice.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drugs | 2000 |
Rat hepatic stellate cells contribute to the acute-phase response with increased expression of alpha1(I) and alpha1(IV) collagens, tissue inhibitor of metalloproteinase-1, and matrix-metalloproteinase-2 messenger RNAs.
Topics: Acute-Phase Reaction; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collage | 2001 |
Plasminogen activators direct reorganization of the liver lobule after acute injury.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Cell Division; Extracellular Matrix Proteins; Fibrin; | 2001 |
[The protective effect of hepatocyte growth-promoting factor (pHGF) against carbon tetrachloride-induced acute liver injury in rats. II. Protective effects on cell membrane injury].
Topics: Acute Disease; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cel | 2001 |
Hepatoprotective activity of Luffa echinata fruits.
Topics: Alanine Transaminase; Alkaline Phosphatase; Analysis of Variance; Animals; Aspartate Aminotransferas | 2001 |
Earlier expression of the transcription factor HFH-11B diminishes induction of p21(CIP1/WAF1) levels and accelerates mouse hepatocyte entry into S-phase following carbon tetrachloride liver injury.
Topics: Animals; Carbon Tetrachloride; cdc25 Phosphatases; Cell Adhesion Molecules; Cell Cycle Proteins; Che | 2001 |
Kinetics and mechanisms of hepatic acute phase response to subtotal partial hepatectomy and cultural impact on environmental hepatic end-stage liver injury in the homeless.
Topics: Acute-Phase Reaction; Aflatoxin B1; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver I | 2001 |
Hepatoprotective activity of indigtone--a bioactive fraction from Indigofera tinctoria Linn.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Fabaceae; Female; Hepatocytes | 2001 |
The role of Smad3 in mediating mouse hepatic stellate cell activation.
Topics: Actins; Animals; Carbon Tetrachloride; Cattle; Cell Division; Cells, Cultured; Chemical and Drug Ind | 2001 |
Medicinal foodstuffs. XXV. Hepatoprotective principle and structures of ionone glucoside, phenethyl glycoside, and flavonol oligoglycosides from young seedpods of garden peas, Pisum sativum L.
Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver Injury; Flavanones; | 2001 |
Effect of central urocortin on carbon tetrachloride-induced acute liver injury in rats.
Topics: Acute Disease; Alanine Transaminase; Animals; Aspartate Aminotransferases; Brain; Carbon Tetrachlori | 2001 |
Plasminogen deficiency leads to impaired lobular reorganization and matrix accumulation after chronic liver injury.
Topics: Afibrinogenemia; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chronic Dise | 2001 |
Plasminogen deficiency results in poor clearance of non-fibrin matrix and persistent activation of hepatic stellate cells after an acute injury.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Extracellular Matr | 2001 |
Differential regulation of TGF-beta signal in hepatic stellate cells between acute and chronic rat liver injury.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Cell Division; Cell Line; Cells, Cultured; Chemical an | 2002 |
[Expression of eNOS and IL-10 gene in signal transduction for liver regeneration].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA; Flow Cytometry; Gene Exp | 1998 |
Adenovirus-mediated gene transfer to nonparenchymal cells in normal and injured liver.
Topics: Adenoviridae; Animals; beta-Galactosidase; Bile Ducts; Carbon Tetrachloride; Coxsackie and Adenoviru | 2002 |
Attenuated acute liver injury in mice by naked hepatocyte growth factor gene transfer into skeletal muscle with electroporation.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Electro | 2002 |
Involvement of endogenous CRF in carbon tetrachloride-induced acute liver injury in rats.
Topics: Acute Disease; Alanine Transaminase; Animals; Atropine Derivatives; Carbon Tetrachloride; Chemical a | 2002 |
Hepatoprotective phenylpropanoids from Scrophularia buergeriana roots against CCl(4)-induced toxicity: action mechanism and structure-activity relationship.
Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cinnamates; | 2002 |
Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Diab | 2002 |
Evaluation of the effectiveness of Rosmarinus officinalis (Lamiaceae) in the alleviation of carbon tetrachloride-induced acute hepatotoxicity in the rat.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Drug Evaluatio | 2002 |
Use of plasma arginase and gamma-glutamyl transpeptidase as specific indicators of heptocellular or hepatobiliary disease in the dog.
Topics: Animals; Arginase; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cholestasis, Extrah | 1979 |
Increased alpha1-fetoprotein production in rat liver injuries induced by various hepatotoxins.
Topics: alpha-Fetoproteins; Aminoacetonitrile; Animals; Carbon Tetrachloride; Chemical and Drug Induced Live | 1976 |
Dissociation of alpha-macrofetoprotein and alpha-fetoprotein production during experimental injury.
Topics: alpha-Fetoproteins; alpha-Macroglobulins; Animals; Carbon Tetrachloride; Ethionine; Galactosamine; H | 1979 |
Diverse mechanisms of hepatocellular injuries due to chemicals: evidence in rats administered carbon tetrachloride or dimethylnitrosamine.
Topics: Age Factors; Animals; Animals, Newborn; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury | 1975 |
Relationship between lysosomal damage, fatty infiltration and hepatocellular necrosis in the course of acute liver injury induced by carbon tetrachloride in the rat.
Topics: Acid Phosphatase; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug I | 1975 |
[Enzyme values of 2 liver homogenates in liver diseases].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Enzymes; Histocytochemistry; | 1977 |
Modification of carbon tetrachloride hepatotoxicity by chemicals.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur | 1977 |
Comparison of in vivo and in vitro drug metabolism in experimental hepatic injury in the rat.
Topics: Acetaminophen; Aminopyrine; Aminopyrine N-Demethylase; Animals; Breath Tests; Carbon Dioxide; Carbon | 1979 |
Possible role of a new metal chelate in the treatment of carbon tetrachloride induced liver damage in squirrels.
Topics: Animals; Carbon Tetrachloride; Chelating Agents; Chemical and Drug Induced Liver Injury; Liver Disea | 1979 |
Renal and hepatic calcification in a lamb poisoned by an anthelmintic dose of carbon tetrachloride.
Topics: Animals; Anthelmintics; Calcinosis; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Female; Ki | 1979 |
Development of resistance to hepatotoxic effect of furylfuramide by pretreatment with its subnecrotic doses and carbon tetrachloride.
Topics: Alanine Transaminase; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Carbon Tetrachloride; | 1978 |
Alanine aminotransferase (GPT) in rainbow trout: plasma enzyme levels as an index of liver damage.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug | 1977 |
Studies on the role of protein syntheis in cell injury by toxic agents: I. Effect of cycloheximide administration on several factors modulating carbon tetrachloride-induced liver necrosis.
Topics: Animals; Body Temperature; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cycloheximi | 1977 |
Effect of different factors modifying the activity of some enzyme systems of the endoplastic reticulum on the sensitivity of cell organelles against the damaging action of chemical agents. I: Interrelations between the activity of some enzyme systems loca
Topics: Acid Phosphatase; Aniline Hydroxylase; Animals; Burns; Carbon Tetrachloride; Chemical and Drug Induc | 1976 |
Quantitative aspects in the assessment of liver injury.
Topics: 1-Propanol; Alanine Transaminase; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Che | 1976 |
Manganese induced hepatic lesions in carbon tetrachloride pretreated rats.
Topics: Administration, Oral; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease | 1975 |
Biliary excretion of 64Cu, 65Zn and 203Hg in the rat with liver injury induced by CCl4.
Topics: Animals; Bile; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chronic Disease; Copper; Female | 1975 |
Distribution and cellular origin of undulin in rat liver.
Topics: Actins; Animals; Carbon Tetrachloride; Cell Adhesion Molecules, Neuronal; Chemical and Drug Induced | 1992 |
Pivotal role of hepatocellular regeneration in the ultimate hepatotoxicity of CCl4 in chlordecone-, mirex-, or phenobarbital-pretreated rats.
Topics: Animals; Autoradiography; Carbon Tetrachloride; Cell Size; Chemical and Drug Induced Liver Injury; C | 1992 |
Zinc status in liver and gastrointestinal diseases.
Topics: Adult; Animals; Carbon Tetrachloride; Carrier Proteins; Chronic Disease; Copper; Gastrointestinal Di | 1992 |
Hepatocyte cytotoxicity induced by various hepatotoxins mediated by cytochrome P-450IIE1: protection with diethyldithiocarbamate administration.
Topics: Animals; Carbon Disulfide; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome | 1992 |
Arachidonate metabolism in D-galactosamine or carbon tetrachloride-induced acute and chronic liver injuries in rats.
Topics: Acute Disease; Animals; Arachidonic Acids; Carbon Tetrachloride; Chemical and Drug Induced Liver Inj | 1992 |
Effect of adenosine 3',5'-cyclic monophosphate derivatives on acute liver injury induced by carbon tetrachloride.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug | 1992 |
Changes in DNA strand breaks in non-parenchymal cells following hepatocyte regeneration in CCl4-induced rat liver injury.
Topics: Animals; Bromodeoxyuridine; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA; Liver | 1992 |
Pharmacokinetics of diazepam in the rat: influence of a carbon tetrachloride-induced hepatic injury.
Topics: Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Proteins; Ca | 1992 |
Phenotypic modulation of perisinusoidal cells following acute liver injury: a quantitative analysis.
Topics: Actins; Acute Disease; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Desmin | 1992 |
Distribution of quinidine in rats with carbon tetrachloride-intoxicated hepatic disease.
Topics: Animals; Blood Proteins; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Hydrogen-Ion | 1992 |
Comparison of the protective effect of Withaferin-'A' and hydrocortisone against CCL4 induced hepatotoxicity in rats.
Topics: Alkaline Phosphatase; Animals; Blood Proteins; Carbon Tetrachloride; Chemical and Drug Induced Liver | 1992 |
Macrophage and perisinusoidal cell kinetics in acute liver injury.
Topics: Animals; Antibodies, Monoclonal; Bromodeoxyuridine; Carbon Tetrachloride; Chemical and Drug Induced | 1992 |
Prevention of carbon tetrachloride-induced liver necrosis by the chelator alizarin sodium sulfonate.
Topics: Animals; Anthraquinones; Body Temperature; Calcium; Carbon Tetrachloride; Chelating Agents; Chemical | 1992 |
Taurine, a possible urinary marker of liver damage: a study of taurine excretion in carbon tetrachloride-treated rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Carbon Tetrachloride; Chemic | 1991 |
Carbon tetrachloride-induced alterations of hepatic calmodulin and free calcium levels in rats pretreated with chlordecone.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Calcium; Calmodulin; Carbon Tetrachlorid | 1991 |
The role of capillarization in hepatic failure: studies in carbon tetrachloride-induced cirrhosis.
Topics: alpha-Fetoproteins; Animals; Asialoglycoproteins; Capillaries; Carbon Tetrachloride; Female; Ferriti | 1991 |
Liver damaging effect of suramin in normal and carbon-tetrachloride treated rats.
Topics: Animals; Body Weight; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Drug Synergism; | 1991 |
Evaluation of root quality of Bupleurum species by TLC scanner and the liver protective effects of "xiao-chai-hu-tang" prepared using three different Bupleurum species.
Topics: Animals; Calibration; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chromatography, | 1991 |
Effects of 1-[(2-thiazolin-2-yl)amino]acetyl-4-(1,3-dithiol-2-ylidene)- 2,3,4,5-tetrahydro-1H-1-benzazepin-3,5-dione hydrochloride (KF-14363) on active oxygen production.
Topics: Animals; Ascitic Fluid; Benzazepines; Biological Factors; Carbon Tetrachloride; Erythrocyte Membrane | 1991 |
Free radical-induced liver injury. II. Effects of intraperitoneally administered 2,2'-azobis(2-amidinopropane) dihydrochloride on the fatty acid profiles of hepatic triacylglycerol and phospholipids.
Topics: Amidines; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Fatty Acids; Free R | 1991 |
Temporal and spatial patterns of proto-oncogene expression at early stages of toxic liver injury in the rat.
Topics: Animals; Antibodies, Monoclonal; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Gene | 1991 |
The pharmacological and pathological studies on Taiwan folk medicine (VI): The effects of Elephantopus scaber subsp. oblanceolata, E. mollis and Pseudoelephantopus spicatus.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug | 1991 |
Protective effects of misoprostol on carbon tetrachloride-induced liver damage in the rat.
Topics: Alprostadil; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced L | 1991 |
Kupffer cells from carbon tetrachloride-injured rat livers produce chemotactic factors for fibroblasts and monocytes: the role of tumor necrosis factor-alpha.
Topics: Animals; Antibodies; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver Injury; | 1991 |
The differential effects of hepatotoxicants on the sulfation pathway in rats.
Topics: 1-Naphthylisothiocyanate; 1-Propanol; Aflatoxin B1; Alanine Transaminase; Animals; Arylsulfotransfer | 1991 |
Influence of liver damage on antipyrine metabolite formation in rats.
Topics: 1-Naphthylisothiocyanate; Animals; Antipyrine; Carbon Tetrachloride; Chemical and Drug Induced Liver | 1991 |
The protective effects of (4R)-hexahydro-7,7-dimethyl-6-oxo-1,2,5-dithiazocine-4-carboxylic acid (SA3443), a novel cyclic disulfide, on chemically-induced acute liver injury.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Azocines; Carbon Tetrachloride; Chemical | 1991 |
Effect of aspartate and glutamate on carbon tetrachloride induced liver damage in rats.
Topics: Animals; Aspartic Acid; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Glutamates; Li | 1990 |
Hypoxia and CCl4-induced liver injury, but not acidosis, impair metabolism of cysteinyl leukotrienes in perfused rat liver.
Topics: Acidosis; Animals; Bile; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Hypoxia; In V | 1990 |
Effects of oxygen deficiency and calcium omission on carbon tetrachloride hepatotoxicity in isolated perfused livers from phenobarbital-pretreated rats.
Topics: Animals; Calcium; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Li | 1990 |
Availability of exchange blood transfusion and plasma exchange in treatment of acute liver failure.
Topics: Acute Disease; Animals; Blood Transfusion; Carbon Tetrachloride; Chemical and Drug Induced Liver Inj | 1990 |
Effect of alpha-blockade on liver regeneration after carbon tetrachloride intoxication in the rat.
Topics: Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; | 1990 |
Evidence of clonal proliferation of hepatocytes after carbon-tetrachloride-induced hepatic injury in PGK-1 mosaic mice.
Topics: Aging; Animals; Carbon Tetrachloride; Cell Division; Chemical and Drug Induced Liver Injury; Clone C | 1990 |
Serum lipid and lipoprotein changes in ponies with experimentally induced liver disease.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cholesterol, HDL; Cholesterol | 1990 |
[Use of hepatocytes cultured in microcarriers for correction of acute hepatic insufficiency].
Topics: Acute Disease; Albumins; Animals; Bilirubin; Carbon Tetrachloride; Cells, Cultured; Chemical and Dru | 1990 |
Lipid quantitation in formalin-fixed liver sections.
Topics: Animals; Azo Compounds; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Fixatives; For | 1988 |
Role of peptide-leukotrienes in liver injury in mice.
Topics: Acetophenones; Animals; Autacoids; Benzoquinones; Carbon Tetrachloride; Chemical and Drug Induced Li | 1989 |
[The effect of pollen on the changes in the liver of laboratory rats evoked by ethionine, carbon tetrachloride, allyl alcohol and galactosamine].
Topics: 1-Propanol; Animals; Carbon Tetrachloride; Ethionine; Galactosamine; Liver; Liver Diseases; Male; Pl | 1989 |
Late preventive effects against carbon tetrachloride-induced liver necrosis of the calcium chelating agent Calcion.
Topics: Animals; Body Temperature; Calcium; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chelating | 1989 |
Effects of valine on 15N incorporation into serum and tissue protein and non-protein fractions following 15N-L-leucine administration to normal and liver-injured rats.
Topics: Amino Acids; Animals; Brain; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; L | 1989 |
Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity in vivo.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Fasting | 1989 |
Variations in serum sorbitol dehydrogenase, aspartate transaminase, and isoenzyme 5 of lactate dehydrogenase activities in horses given carbon tetrachloride.
Topics: Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; | 1989 |
Hepatic sinusoidal cell destruction in the development of intravascular coagulation in acute liver failure of rats.
Topics: Animals; Carbon Tetrachloride; Cell Survival; Chemical and Drug Induced Liver Injury; Dimethylnitros | 1989 |
In vivo effects of immunostimulating lipopeptides on mouse liver microsomal cytochromes P-450 and on paracetamol-induced toxicity.
Topics: Acetaminophen; Adjuvants, Immunologic; Animals; Carbon Tetrachloride; Chemical and Drug Induced Live | 1989 |
Alpha 1-antitrypsin and hepatic fibrosis.
Topics: alpha 1-Antitrypsin; Animals; Carbon Tetrachloride; Liver; Liver Cirrhosis, Experimental; Liver Dise | 1989 |
Intrasplenic hepatocyte transplantation in rats with experimental liver injury: morphological and morphometric studies.
Topics: Animals; Bile Ducts; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Liver; Liver Dise | 1989 |
Laboratory assessment of hepatic injury in the woodchuck (Marmota monax).
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Blood Proteins; Ca | 1985 |
1,2-Dibromoethane initiation of hepatic nodules in Sprague-Dawley rats selected with Solt-Farber system.
Topics: 2-Acetylaminofluorene; Administration, Oral; Animals; Carbon Tetrachloride; Chemical and Drug Induce | 1985 |
Comparative study on the sensitivity of several serum enzymes in detecting hepatic damage in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Carbon | 1985 |
Effect of rioprostil and colchicine on CCl4-acute liver damage in rats. Relationship with plasma membrane lipids.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bilirubin; Carbon Tetrachloride; Cell Membrane; | 1987 |
The influence of experimentally induced pathological states on the flow and composition of central lymph in the rat.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Chronic Disease; Fasting; Female; Kidney Diseases; Liv | 1986 |
Suppression of delayed-type hypersensitivity mediated by macrophage-like cells in mice with experimental liver injury.
Topics: 1-Naphthylisothiocyanate; Animals; Carbon Tetrachloride; Catechin; Chemical and Drug Induced Liver I | 1985 |
Late preventive effects of trifluoperazine on carbon tetrachloride-induced hepatic necrosis.
Topics: Animals; Body Temperature; Carbon Radioisotopes; Carbon Tetrachloride; Chemical and Drug Induced Liv | 1986 |
The drug methoxsalen, a suicide substrate for cytochrome P-450, decreases the metabolic activation, and prevents the hepatotoxicity, of carbon tetrachloride in mice.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochr | 1987 |
[The effect of the infusion of Haploppapus baylahuen in dogs with liver damage induced by carbon tetrachloride].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dog Diseases; Dogs; Liver Dis | 1988 |
Effects of epidermal growth factor, glucagon and insulin on the hepatocytes after experimental liver cell necrosis. In vivo studies with monoclonal anti-bromo-deoxyuridine staining.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA; Epidermal Growth Factor; | 1988 |
Protection against carbon tetrachloride hepatotoxicity by 5,10-dihydroindeno[1,2-b]indole, a potent inhibitor of lipid peroxidation.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Carbon Tetrachloride; Chemical and Drug Induced | 1988 |
Blood clearance of 99mTc-phytate for evaluation of hepatic dysfunction in rats.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Liver; Liver Diseases; Male; | 1988 |
Blood clearance of 99mTc-phytate for evaluation of hepatic dysfunction in dogs.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug | 1988 |
[Kupffer cell-derived growth factor in fibroblasts in acute liver injury induced by carbon tetrachloride].
Topics: Acute Disease; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Fibroblast Gro | 1988 |
Decreased diuretic response to furosemide in rats with acute hepatic failure.
Topics: Adrenalectomy; Aldosterone; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; D | 1988 |
[Evaluation of serum cathepsin B-like activity in liver diseases].
Topics: Animals; Carbon Tetrachloride; Cathepsin B; Chemical and Drug Induced Liver Injury; Galactosamine; H | 1988 |
Effects of ventromedial and lateral hypothalamic stimulation on chemically-induced liver injury in rats.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Denerva | 1988 |
Exchange blood transfusion for acute hepatic failure: its limited availability depending on the type of injury in rats.
Topics: Acute Disease; Alanine Transaminase; Animals; Blood Coagulation; Carbon Tetrachloride; Chemical and | 1988 |
Effect of branched-chain amino acid on 15N incorporation into liver and skeletal muscle proteins following [15N]-ammonium chloride administration to carbon tetrachloride-intoxicated rats.
Topics: Amino Acids, Branched-Chain; Ammonium Chloride; Animals; Carbon Tetrachloride; Chemical and Drug Ind | 1988 |
Lipid peroxidation and cell viability in isolated hepatocytes in a redesigned oxystat system: evaluation of the hypothesis that lipid peroxidation, preferentially induced at low oxygen partial pressures, is decisive for CCl4 liver cell injury.
Topics: Animals; Carbon Tetrachloride; Cell Survival; Chemical and Drug Induced Liver Injury; In Vitro Techn | 1988 |
Intravascular coagulation in acute liver failure in rats and its treatment with antithrombin III.
Topics: Animals; Antithrombin III; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dimethylnit | 1988 |
Hepatic protection from chemical injury by isoflurane.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug | 1988 |
Effects of methyl (+) (3S)-1,2,3,4-tetrahydro-3-hydroxymethyl-beta-carboline-2- carbodithioate(THC), a new hepatoprotective agent, on protein synthesis and chronic liver injury induced by carbon tetrachroride in rats.
Topics: Animals; Body Weight; Carbolines; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Live | 1987 |
The influence of single or repeated phlebotomy on the physiological condition of normal and diseased rats.
Topics: Anemia; Animals; Blood Cell Count; Blood Pressure; Bloodletting; Carbon Tetrachloride; Chemical and | 1987 |
Protein synthesis in Ito cells (fat-storing cells) of cultured liver tissues from CCL4-treated mice. A light and electron microscopic autoradiographic study.
Topics: Animals; Autoradiography; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Culture Tech | 1987 |
In vivo protection by protein A of hepatic microsomal mixed function oxidase system of CCl4-administered rats.
Topics: Alanine Transaminase; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Aryl Hydrocarbon Hydr | 1987 |
The effect of acute hepatic injury on the disposition of vitamin A in the rat.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Liver; Liver Diseases; Male; Rats; Rats, Inbred Strain | 1986 |
Potentiation of carbon tetrachloride hepatotoxicity by hypoxia.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug | 1986 |
Changes of haemostaseological variables in carbon tetrachloride poisoning in rats.
Topics: Animals; Antithrombin III; Blood Coagulation Tests; Carbon Tetrachloride; Carbon Tetrachloride Poiso | 1985 |
Hyperbaric oxygen protection against carbon tetrachloride hepatotoxicity in the rat. Association with altered metabolism.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Hyperbaric Oxygenation; Liver | 1986 |
Liver damage does not increase the sensitivity of mice to cyanide given acutely.
Topics: Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; | 1986 |
[Substance-induced liver injury as a model for evaluating hepatoprotective drugs].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug | 1985 |
[Therapeutic effect of TRQ on chronic liver injury model in rats induced by CCl4].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Carbon Tetrachloride; Chemi | 1985 |
Propionate loading test for liver function during experimental liver necrosis in sheep.
Topics: Animals; Blood Glucose; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; Glucon | 1985 |
An investigation into the association between liver damage and metastatic uveal melanoma.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cricetinae; Liver Diseases; L | 1985 |
Ethanol potentiation of carbon tetrachloride hepatotoxicity: possible role for the in vivo inhibition of aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytos | 1985 |
[Excretion of phenoltetrachlorophthalein in rats with experimental liver lesions].
Topics: Animals; Bile; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; Liver Diseases; | 1985 |
The application of some liver function tests to sheep dosed with carbon tetrachloride and hexachlorphene.
Topics: Alkaline Phosphatase; Animals; Arginase; Aspartate Aminotransferases; Bilirubin; Blood Proteins; Car | 1971 |
The comparison of arginine content in serum proteins in rats with Guerin tumour and in experimental induced intoxication with CCl 4 and HgCl 2 .
Topics: Alkaline Phosphatase; Alpha-Globulins; Animals; Arginine; Beta-Globulins; Blood Proteins; Carbon Tet | 1971 |
Liver parenchymal cell injury. VII. Membrane denaturation following carbon tetrachloride.
Topics: Animals; Carbon Isotopes; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Membrane; Chemi | 1971 |
Influence of cold environment on hepatic changes produced by repeated doses of carbon tetrachloride.
Topics: Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Carbon Tetrachloride; Carbon Tetrachloride | 1972 |
Distribution of clioquinol in rats with hepatic dysfunction.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Clioquinol; Fatty Liver; Iodi | 1973 |
Gamma-glutamyl transpeptidase: a clinical and experimental study.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bile Ducts; Carbon | 1972 |
[Etiology of necrotic changes in organs of fattened geese. II. Attempts at infecting geese with S. necrogenes and prophylactic action of chlorocycline Polfa and deworming with carbon tetrachloride].
Topics: Animals; Carbon Tetrachloride; Fusobacterium Infections; Geese; Liver; Liver Diseases; Necrosis; Nem | 1974 |
[Pharmacological study on thiamine triphosphate (TTP)].
Topics: Adenosine Triphosphatases; Animals; Anura; Blood Pressure; Carbon Tetrachloride; Cats; Cerebral Cort | 1967 |
The role of perisinusoidal cells in experimental hepatic fibrogenesis.
Topics: Animals; Autoradiography; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagen; En | 1972 |
Importance of the route of administration of ccl 4 in the protective effect of promethazine.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Glucose-6-Phosp | 1973 |
Sulfaguanidine protection of mouse liver from carbon tetrachloride-induced necrosis.
Topics: Aniline Compounds; Animals; Autoradiography; Carbon Tetrachloride; Chemical and Drug Induced Liver I | 1973 |
Effect of carbon tetrachloride on induction of liver enzymes by acute stress or corticosterone.
Topics: Adrenalectomy; Alanine Transaminase; Alkaline Phosphatase; Animals; Carbon Tetrachloride; Chemical a | 1969 |
[Effect of experimental liver damage on the reduction of testosterone and 4-androstene-3,17-dione].
Topics: 17-Ketosteroids; Androstanes; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; | 1972 |
Effect of splenectomy on acute hepatic injury by carbon tetrachloride in albino rats.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; Liver; | 1974 |
Hepatogenous photosensitization its induction and study in guinea pigs.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Carbon | 1974 |
[Experimental carbon tetrachloride poisoning and fat embolism in rabbits].
Topics: Administration, Oral; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Disease Models, | 1974 |
Pyrazole blockade of carbon tetrachloride activation and liver necrosis.
Topics: Animals; Carbon Isotopes; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug In | 1972 |
The effect of pancreatectomy and other agents on iron absorption and storage in the rat.
Topics: Absorption; Animals; Atrophy; Carbon Tetrachloride; Ethionine; Female; Hemosiderin; Iron; Iron Isoto | 1973 |
Experimental hepatic necrosis: studies on coagulation abnormalities, plasma clearance, and organ distribution of 125I-labelled fibrinogen.
Topics: Animals; Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Coagulation Tests; Body Weight; | 1973 |
The metabolism of the isolated perfused canine liver.
Topics: Animals; Carbohydrate Metabolism; Carbon Dioxide; Carbon Tetrachloride; Chemical and Drug Induced Li | 1973 |
Studies on aminopeptidases in rat liver and plasma.
Topics: Aminopeptidases; Animals; Bromelains; Carbon Tetrachloride; Catheterization; Chemical and Drug Induc | 1973 |
Massive liver cell necrosis induced in the pig with carbon tetrachloride.
Topics: Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug | 1974 |
Susceptibility of rabbits to pyrogenic and lethal effects of endotoxin after acute liver injury.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Endotoxins; Escherichia coli; | 1968 |
In-vivo nuclear localisation of human antinuclear antibodies in mice with carbon tetrachloride- and thioacetamide-induced hepatic necrosis.
Topics: Amides; Animals; Antibodies, Antinuclear; Carbon Tetrachloride; Chemical and Drug Induced Liver Inju | 1970 |
Investigations on liver enzyme activity in test animals previously subjected to experimental injuries and under conditions of drinking Hissar mineral water from the "Momina Banja" spring.
Topics: Alkaline Phosphatase; Animals; Carbon Tetrachloride; Fructose-Bisphosphate Aldolase; Liver; Liver Di | 1966 |
[Phosphofructaldose activity in acute liver damage of the horse].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Fructose-Bisphosphate Aldolas | 1967 |
The role of triglyceride accumulation and of necrosis in the hemodynamic responses of the isolated perfused rat liver after administration of carbon tetrachloride.
Topics: Acetates; Amides; Animals; Body Temperature; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; C | 1969 |
Hepatotoxicity of carbon tetrachloride in sheep. 2. Influence of ingestion of Heliotropium europaeum.
Topics: Animal Nutritional Physiological Phenomena; Animals; Aspartate Aminotransferases; Biopsy; Carbon Tet | 1972 |
Sensitivity of several serum enzymes in detecting carbon tetrachloride-induced liver damage in rats.
Topics: Animals; Arginine; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Clinical Enzyme Tests; Eryt | 1972 |
Prevention by cystamine of liver necrosis and early biochemical alterations induced by carbon tetrachloride.
Topics: Administration, Oral; Animals; Carbon Isotopes; Carbon Tetrachloride; Carbon Tetrachloride Poisoning | 1972 |
Selective potentiation of carbon tetrachloride hepatotoxicity by ethanol.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Dr | 1971 |
Effect of carbon tetrachloride induced progressive liver damage on the metabolism of hexobarbital and bilirubin in vivo.
Topics: Animals; Bilirubin; Body Weight; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Hexob | 1971 |
[Patterns of rat liver damage following intrasplenic injection of differentially dispersed carbon tetrachloride].
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur | 1971 |
[Reduction of testosterone and androst-4en-3,17-dione in experimentally damaged rat liver].
Topics: 17-Ketosteroids; Androstanes; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; | 1971 |
Effects of phenobarbital pretreatment on the hepatotoxicity of carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Drug Synergism; Injections, Intraperi | 1970 |
[Clinical evaluation of active and potentially active form of factor XIII].
Topics: Adult; Carbon Tetrachloride; Child; Cysteine; Disseminated Intravascular Coagulation; Factor XIII; H | 1970 |
Inactivation of gastrin-like synthetic peptide by the liver and serum, and its clinical significance.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Gastric Juice; Gastrins; Live | 1971 |
Effect of inhibitors of drug metabolizing enzymes on carbon tetrachloride hepatotoxicity.
Topics: Aminopyrine; Animals; Biotransformation; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemi | 1971 |
Disturbances in the permeability of the cerebral blood vessels in experimental hepatic encephalopathy.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Chemistry; Brain Diseases; Carbon Tetrachloride; Female; | 1971 |
Comparative studies on plasma and tissue sorbitol, glutamic, lactic and hydroxybutyric dehydrogenase and transaminase activities in the dog.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Dogs; Glutamate De | 1971 |
[Histochemical and biochemical behavior of beta-glucuronidase in experimental liver parenchymal lesions].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Glucuronidase; Histocytochemi | 1967 |
[The inhibition of carbon tetrachloride induced liver fibrosis in rats with aminoacetonitrile].
Topics: Acetates; Amines; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagen; C | 1967 |
The clinical and experimental studies on the metabolism of folic acid using tritiated folic acid. 3. Plasma clearance in man and organ distribution in rat following intravenous administration of tritiated folic acid.
Topics: Acute Disease; Animals; Body Weight; Bone Marrow; Carbon Tetrachloride; Chronic Disease; Folic Acid; | 1968 |
A comparison of the chronic effects of irradiation upon the normal, damaged, and regenerating rat liver.
Topics: Animals; Body Weight; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; Iodine R | 1968 |
Portal hypertension in acute experimental veno-occlusive disease of the liver in rats.
Topics: Anesthesia, Inhalation; Animals; Blood Pressure Determination; Carbon Tetrachloride; Chemical and Dr | 1969 |
[Experimental hepathic enchalopathy in rat. Clinical and electrocorticographic study].
Topics: Animals; Ataxia; Brain Diseases; Carbon Tetrachloride; Cerebral Cortex; Coma; Cyanosis; Electroencep | 1969 |
Clinical studies on serum ionic calcium in domestic animals. VI. Effect of intravenous injection of calcium ion solution in healthy animals and those with liver damage.
Topics: Animals; Bone Marrow; Calcium; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dogs; I | 1965 |
Clinical studies on serum ionic calcium in domestic animals. VII. Effect of peroral administration of calcium on rabbits with liver damaged experimentally.
Topics: Animals; Calcium; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Ions; Liver Diseases | 1965 |