carbon tetrachloride has been researched along with Kidney Failure in 9 studies
Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Kidney Failure: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Forty Sprague-Dawley rats with carbon tetrachloride-induced liver cirrhosis and 20 control rats were intraperitoneally administered a single dose of DEG, and randomly killed 1, 2, 5 or 8 days following exposure." | 7.77 | Pre-existing liver cirrhosis reduced the toxic effect of diethylene glycol in a rat model due to the impaired hepatic alcohol dehydrogenase. ( , 2011) |
| " Forty Sprague-Dawley rats with carbon tetrachloride-induced liver cirrhosis and 20 control rats were intraperitoneally administered a single dose of DEG, and randomly killed 1, 2, 5 or 8 days following exposure." | 3.77 | Pre-existing liver cirrhosis reduced the toxic effect of diethylene glycol in a rat model due to the impaired hepatic alcohol dehydrogenase. ( , 2011) |
| "These results suggested that not only hepatic failure but also renal failure could modify the pharmacokinetics of paclitaxel in vivo." | 3.73 | Altered pharmacokinetics of paclitaxel in experimental hepatic or renal failure. ( Inui, K; Jiko, M; Okuda, M; Yano, I, 2005) |
| "The knowledge of pharmacokinetic and pharmacodynamic properties of antiepileptic drugs is helpful in optimizing drug therapy for epilepsy." | 1.46 | Evaluation of Brain Pharmacokinetic and Neuropharmacodynamic Attributes of an Antiepileptic Drug, Lacosamide, in Hepatic and Renal Impairment: Preclinical Evidence. ( Kumar, B; Medhi, B; Modi, M; Saikia, B, 2017) |
| " Both conditions failed to cause a significant effect on Cmax or Tmax." | 1.40 | Effect of experimentally induced hepatic and renal failure on the pharmacokinetics of topiramate in rats. ( Matar, KM; Tayem, YI, 2014) |
| "Chronic kidney disease, end-stage renal failure, and liver diseases are increasing worldwide and constitute a huge burden on health care costs, with attendant high morbidity and debility." | 1.40 | Hepato- and nephroprotective activities of a Nigerian local king tuber oyster mushroom, Pleurotus tuberregium (higher Basidiomycetes), in chemically induced organ toxicities in rats. ( Akah, PA; Ihim, SA; Laiyemo, KA; Nworu, CS; Ugwu, LE, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumar, B | 1 |
| Modi, M | 1 |
| Saikia, B | 1 |
| Medhi, B | 1 |
| Ma, JQ | 1 |
| Ding, J | 1 |
| Xiao, ZH | 1 |
| Liu, CM | 1 |
| Matar, KM | 1 |
| Tayem, YI | 1 |
| Nworu, CS | 1 |
| Ihim, SA | 1 |
| Ugwu, LE | 1 |
| Laiyemo, KA | 1 |
| Akah, PA | 1 |
| PEARSON, CC | 1 |
| Hsouna, AB | 1 |
| Saoudi, M | 1 |
| Trigui, M | 1 |
| Jamoussi, K | 1 |
| Boudawara, T | 1 |
| Jaoua, S | 1 |
| Feki, AE | 1 |
| SIROTA, JH | 1 |
| Jiko, M | 1 |
| Yano, I | 1 |
| Okuda, M | 1 |
| Inui, K | 1 |
9 other studies available for carbon tetrachloride and Kidney Failure
| Article | Year |
|---|---|
Evaluation of Brain Pharmacokinetic and Neuropharmacodynamic Attributes of an Antiepileptic Drug, Lacosamide, in Hepatic and Renal Impairment: Preclinical Evidence.
Topics: Acetamides; Administration, Oral; Animals; Anticonvulsants; Area Under Curve; Brain; Carbon Tetrachl | 2017 |
Ursolic acid ameliorates carbon tetrachloride-induced oxidative DNA damage and inflammation in mouse kidney by inhibiting the STAT3 and NF-κB activities.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Cyclooxygenase 2; DNA Damage; Inflammation; Interleukin | 2014 |
Effect of experimentally induced hepatic and renal failure on the pharmacokinetics of topiramate in rats.
Topics: Animals; Anti-Obesity Agents; Antineoplastic Agents; Carbon Tetrachloride; Carbon Tetrachloride Pois | 2014 |
Hepato- and nephroprotective activities of a Nigerian local king tuber oyster mushroom, Pleurotus tuberregium (higher Basidiomycetes), in chemically induced organ toxicities in rats.
Topics: Acetaminophen; Animals; Anti-Bacterial Agents; Carbon Tetrachloride; Complex Mixtures; Disease Model | 2014 |
Carbon tetrachloride intoxication with acute hepatic and renal failure treated with peritoneal lavage; report of case.
Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Liver; Peritoneal Lavage; Renal Insufficiency | 1947 |
Pre-existing liver cirrhosis reduced the toxic effect of diethylene glycol in a rat model due to the impaired hepatic alcohol dehydrogenase.
Topics: Alcohol Dehydrogenase; Animals; Carbon Tetrachloride; Disease Models, Animal; Ethylene Glycols; Hepa | 2011 |
Characterization of bioactive compounds and ameliorative effects of Ceratonia siliqua leaf extract against CCl₄ induced hepatic oxidative damage and renal failure in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Carbon Tetrach | 2011 |
Carbon tetrachloride poisoning in man; the mechanisms of renal failure and recovery.
Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Humans; Male; Renal Insufficiency | 1949 |
Altered pharmacokinetics of paclitaxel in experimental hepatic or renal failure.
Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Liver Failure; Male; Metabolic Cleara | 2005 |