carbon tetrachloride has been researched along with Hyperplasia in 27 studies
Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present experiments we investigated the efficiency of a primary hepatocyte mitogen 1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene (TCPOBOB) on two different liver cirrhosis/fibrosis models in mice induced by chronic administration of CCl(4) and thioacetamide respectively." | 3.78 | 1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene induces substantial hyperplasia in fibrotic mouse liver. ( Bugyik, E; Dezso, K; Nagy, P; Paku, S; Szurián, K; Turányi, E, 2012) |
| "The steady-state levels of c-fos, c-jun and c-myc messenger RNA were investigated in rat liver tissue after proliferative stimuli of different nature-namely, compensatory regeneration induced by partial hepatectomy or carbon tetrachloride administration-and direct hyperplasia induced by four different hepatomitogens: lead nitrate, ethylene dibromide, cyproterone acetate and nafenopin." | 3.68 | Differences in the steady-state levels of c-fos, c-jun and c-myc messenger RNA during mitogen-induced liver growth and compensatory regeneration. ( Columbano, A; Coni, P; de Prati, AC; Ledda-Columbano, GM; Menegazzi, M; Sarma, DS; Simbula, G; Suzuki, H, 1993) |
| " Animals were given a single dose of diethylnitrosamine (100 mg/kg body weight)." | 3.68 | Cell proliferation and promotion of rat liver carcinogenesis: different effect of hepatic regeneration and mitogen induced hyperplasia on the development of enzyme-altered foci. ( Chelo, A; Columbano, A; Curto, M; Ennas, MG; Ledda-Columbano, GM; Pani, P, 1990) |
| "Experiments were designed to investigate the expression of three cell-cycle-dependent proto-oncogenes in response to two different types of proliferative stimuli: compensatory cell proliferation after partial hepatectomy (PH) or CCl4 and liver hyperplasia induced by the mitogens ethylene dibromide (EDB) and cyproterone acetate (CPA)." | 3.68 | Liver hyperplasia is not necessarily associated with increased expression of c-fos and c-myc mRNA. ( Columbano, A; Coni, P; Ledda-Columbano, GM; Pichiri-Coni, G; Rajalakshmi, S; Rao, PM; Sarma, DS, 1990) |
| "Transforming growth factor beta1 (TGF-beta1) has been implicated as inhibitor of cell proliferation and a potent inducer of apoptosis in vitro and in vivo after the administration of high doses." | 1.30 | Levels of transforming growth factor beta and transforming growth factor beta receptors in rat liver during growth, regression by apoptosis and neoplasia. ( Bursch, W; Grasl-Kraupp, B; Kammerer, B; Müllauer, L; Rossmanith, W; Ruttkay-Nedecky, B; Schulte-Hermann, R, 1998) |
| "In diethylnitrosamine (DEN)-treated rats, which were fed a N-2-fluorenylacetamide (FAA)-containing diet and additionally treated with repeated CCl4 injections, gamma-glutamyl transpeptidase (gamma-GTP)-positive hyperplastic nodules were markedly developed in the 8th week of the experiment." | 1.27 | Effects of carbon tetrachloride and azathioprine on diethylnitrosamine and N-2-fluorenylacetamide-induced hyperplastic liver nodule and hepatocellular carcinoma. ( Sakata, T, 1984) |
| " The results from the multiple-dose studies showed a similar relationship except that with 20 mg/kg X d the concentrations of SGOT and SGPT decayed to control values after 14 d of dosing whereas the percentage of hepatocytes in S phase remained markedly elevated (greater than 10 X control)." | 1.27 | Relationship between hepatotoxicity and induction of replicative DNA synthesis following single or multiple doses of carbon tetrachloride. ( Doolittle, DJ; Muller, G; Scribner, HE, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (55.56) | 18.7374 |
| 1990's | 10 (37.04) | 18.2507 |
| 2000's | 1 (3.70) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bugyik, E | 1 |
| Dezso, K | 1 |
| Turányi, E | 1 |
| Szurián, K | 1 |
| Paku, S | 1 |
| Nagy, P | 1 |
| BARRY, WE | 1 |
| DAY, HJ | 1 |
| LAHTIHARJU, A | 1 |
| Gonzales, PH | 1 |
| Rhoden, CR | 1 |
| Luz, C | 1 |
| Corrêa, G | 1 |
| Barbosa-Coutinho, LM | 1 |
| Oliveira, MC | 1 |
| Leonard, TB | 1 |
| Neptun, DA | 1 |
| Popp, JA | 2 |
| Hasegawa, R | 2 |
| Tatematsu, M | 2 |
| Tsuda, H | 1 |
| Shirai, T | 1 |
| Hagiwara, A | 1 |
| Ito, N | 2 |
| Sakata, T | 1 |
| Imaida, K | 1 |
| Murasaki, G | 1 |
| Murkofsky, RL | 1 |
| Glover, SE | 1 |
| Miller, RT | 1 |
| Cattley, RC | 1 |
| Coni, P | 4 |
| Simbula, G | 1 |
| de Prati, AC | 1 |
| Menegazzi, M | 2 |
| Suzuki, H | 2 |
| Sarma, DS | 3 |
| Ledda-Columbano, GM | 6 |
| Columbano, A | 6 |
| Carcereri-De Prati, A | 1 |
| Shinozuka, H | 1 |
| Pibiri, M | 1 |
| Piga, R | 1 |
| Grasl-Kraupp, B | 1 |
| Rossmanith, W | 1 |
| Ruttkay-Nedecky, B | 1 |
| Müllauer, L | 1 |
| Kammerer, B | 1 |
| Bursch, W | 1 |
| Schulte-Hermann, R | 1 |
| Kozuka, S | 1 |
| Sassa, R | 1 |
| Farber, E | 1 |
| Parker, S | 1 |
| Gruenstein, M | 1 |
| FitzGerald, MJ | 1 |
| Folan, JC | 1 |
| O'Brien, TM | 1 |
| Curto, M | 2 |
| Giacomini, L | 1 |
| Faa, G | 1 |
| Sirica, AE | 1 |
| Williams, TW | 1 |
| Tomaszewski, KE | 1 |
| Harries, GC | 1 |
| Jeffrey, P | 1 |
| Ennas, MG | 1 |
| Chelo, A | 1 |
| Pani, P | 2 |
| Slater, TF | 1 |
| Cheeseman, KH | 1 |
| Benedetto, C | 1 |
| Collins, M | 1 |
| Emery, S | 1 |
| Maddix, SP | 1 |
| Nodes, JT | 1 |
| Proudfoot, K | 1 |
| Burton, GW | 1 |
| Ingold, KU | 1 |
| Pichiri-Coni, G | 1 |
| Rao, PM | 1 |
| Rajalakshmi, S | 1 |
| Liguori, C | 1 |
| Doolittle, DJ | 1 |
| Muller, G | 1 |
| Scribner, HE | 1 |
| Reuber, MD | 1 |
| Hals, E | 1 |
| Björlin, G | 1 |
| Jacobsen, K | 1 |
| Ueda, Y | 1 |
| Pham-Huu-Trung, MT | 1 |
27 other studies available for carbon tetrachloride and Hyperplasia
| Article | Year |
|---|---|
1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene induces substantial hyperplasia in fibrotic mouse liver.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biomarkers; Bromodeoxyuridine; Carbon Tetrachloride; Cell Pr | 2012 |
REFRACTORY SIDEROBLASTIC ANEMIA. CLINICAL AND HEMATOLOGIC STUDY OF TEN CASES.
Topics: Anemia; Anemia, Sideroblastic; Benzene; Bone Marrow; Carbon Tetrachloride; Geriatrics; Hematology; H | 1964 |
[THE REGENERATIVE REACTION TO A SINGLE ADMINISTRATION OF CARBON TETRACHLORIDE IN DIFFERENT TISSUES].
Topics: Animals; Autoradiography; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Division; Hyper | 1964 |
Male gonadal function, prolactin secretion and lactotroph population in an experimental model of cirrhosis.
Topics: Animals; Carbon Tetrachloride; Cell Count; Estradiol; Follicle Stimulating Hormone; Gonadotropins, P | 2007 |
Serum gamma glutamyl transferase as a specific indicator of bile duct lesions in the rat liver.
Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Alkaline Phosphatase; Animals; Bile Acids and Salts; | 1984 |
Induction of hyperplastic liver nodules in hepatectomized rats treated with 3'-methyl-4-dimethylaminoazobenzene, benzo[a]pyrene or phenobarbital before or after exposure to N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzopyrenes; Carbon Tetrachloride; Hepatectomy; Hyp | 1982 |
Effects of carbon tetrachloride and azathioprine on diethylnitrosamine and N-2-fluorenylacetamide-induced hyperplastic liver nodule and hepatocellular carcinoma.
Topics: 2-Acetylaminofluorene; Aniline Hydroxylase; Animals; Azathioprine; Carbon Tetrachloride; Diethylnitr | 1984 |
Effects of various promoters on the induction of hyperplastic nodules in rat liver.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinogens; Diethylnitrosamine; Hyperplasia; | 1980 |
Effect of regeneration and hyperplasia on levels of DNA base oxidation in rat liver.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carbon Tetrachloride; Cell Division; Deoxyguanosine; Hyperplas | 1993 |
Differences in the steady-state levels of c-fos, c-jun and c-myc messenger RNA during mitogen-induced liver growth and compensatory regeneration.
Topics: Animals; Carbon Tetrachloride; Cell Division; Cyproterone Acetate; Ethylene Dibromide; Gene Expressi | 1993 |
Liver cell proliferation induced by nafenopin and cyproterone acetate is not associated with increases in activation of transcription factors NF-kappaB and AP-1 or with expression of tumor necrosis factor alpha.
Topics: Animals; Binding, Competitive; Carbon Tetrachloride; Cell Division; Cyproterone Acetate; Hepatectomy | 1997 |
Levels of transforming growth factor beta and transforming growth factor beta receptors in rat liver during growth, regression by apoptosis and neoplasia.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Female; Hyperplasia; Liver; Liver Neoplasms, Experimental; | 1998 |
Acceleration of hepatocarcinogenesis of 2,7-bis(acetamido)fluorene by carbon tetrachloride and time relation of treatment.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Female; Fluorenes; | 1976 |
The resistance of putative premalignant liver cell populations, hyperplastic nodules, to the acute cytotoxic effects of some hepatocarcinogens.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinogens; Cell Transformation, Neoplastic; | 1976 |
The innervation of hyperplastic epidermis in the mouse: a light microscopic study.
Topics: Acids; Alkanes; Animals; Benzene; Bromides; Carbon Tetrachloride; Chloroform; Creosote; Formaldehyde | 1975 |
Mitogen-induced liver hyperplasia does not substitute for compensatory regeneration during promotion of chemical hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Cell Division; Diethylnitrosamine; gamma-Gluta | 1992 |
Appearance of ductular hepatocytes in rat liver after bile duct ligation and subsequent zone 3 necrosis by carbon tetrachloride.
Topics: Animals; Bile Ducts; Carbon Tetrachloride; Cell Differentiation; Hyperplasia; Immunohistochemistry; | 1992 |
The production of hepatic cirrhosis in rats.
Topics: Animals; Body Weight; Carbon Tetrachloride; Fibrosis; Hyperplasia; Hypertrophy; Liver; Liver Cirrhos | 1991 |
Cell proliferation and promotion of rat liver carcinogenesis: different effect of hepatic regeneration and mitogen induced hyperplasia on the development of enzyme-altered foci.
Topics: Adenosine Triphosphatases; Animals; Body Weight; Carbon Tetrachloride; Cell Division; Diethylnitrosa | 1990 |
Studies on the hyperplasia ('regeneration') of the rat liver following partial hepatectomy. Changes in lipid peroxidation and general biochemical aspects.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; DNA; Fatty Acids; Hepat | 1990 |
Liver hyperplasia is not necessarily associated with increased expression of c-fos and c-myc mRNA.
Topics: Animals; Carbon Tetrachloride; Cell Division; Cyproterone; Cyproterone Acetate; Ethylene Dibromide; | 1990 |
Liver cell proliferation induced by the mitogen ethylene dibromide, unlike compensatory cell proliferation, does not achieve initiation of rat liver carcinogenesis by diethylnitrosamine.
Topics: Animals; Carbon Tetrachloride; Cell Division; Diethylnitrosamine; Ethylene Dibromide; gamma-Glutamyl | 1987 |
Relationship between hepatotoxicity and induction of replicative DNA synthesis following single or multiple doses of carbon tetrachloride.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; DNA; DNA Repair; D | 1987 |
Effect of 3-methylcholanthrene on hyperplastic and early neoplastic hepatic lesions induced in rats by carbon tetrachloride.
Topics: Age Factors; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Carcinogens; Carcinoma, | 1970 |
Histopathological changes in rat incisors in experimental carbon tetrachloride intoxication.
Topics: Alkaline Phosphatase; Amelogenesis; Animals; Bilirubin; Carbon Tetrachloride; Chemical and Drug Indu | 1973 |
The relation between experimental liver carcinoma and liver cirrhosis induced by successive administration of p-dimethylaminoazobenzene and carbon tetrachloride.
Topics: Animals; Body Weight; Carbon Tetrachloride; Hyperplasia; Liver; Liver Cirrhosis; Liver Neoplasms; p- | 1967 |
[Determination of plasma cortisol by competitive binding with transcortin].
Topics: Addison Disease; Adsorption; Binding Sites; Carbon Tetrachloride; Coal; Dextrans; Fluorometry; Human | 1970 |