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carbon tetrachloride and Hepatic Encephalopathy

carbon tetrachloride has been researched along with Hepatic Encephalopathy in 22 studies

Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.

Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)

Research Excerpts

ExcerptRelevanceReference
" In this study, we investigated whether 3-genes iPSC transplantation is capable of rescuing carbon tetrachloride (CCl(4))-induced fulminant hepatic failure and hepatic encephalopathy in mice."7.78Improvement of carbon tetrachloride-induced acute hepatic failure by transplantation of induced pluripotent stem cells without reprogramming factor c-Myc. ( Chang, HM; Chang, YL; Chen, HL; Chen, LK; Chen, SY; Chen, YJ; Chiang, CH; Chien, Y; Hsieh, JH; Huo, TI; Jeng, SY; Lai, YH; Li, HY; Liao, YW; Peng, CH, 2012)
" In this study, we investigated whether 3-genes iPSC transplantation is capable of rescuing carbon tetrachloride (CCl(4))-induced fulminant hepatic failure and hepatic encephalopathy in mice."3.78Improvement of carbon tetrachloride-induced acute hepatic failure by transplantation of induced pluripotent stem cells without reprogramming factor c-Myc. ( Chang, HM; Chang, YL; Chen, HL; Chen, LK; Chen, SY; Chen, YJ; Chiang, CH; Chien, Y; Hsieh, JH; Huo, TI; Jeng, SY; Lai, YH; Li, HY; Liao, YW; Peng, CH, 2012)
"Hepatic encephalopathy is a neurologic syndrome secondary to liver failure that causes cognitive and motor abnormalities."1.33Functional abnormalities of the motor tract in the rat after portocaval anastomosis and after carbon tetrachloride induction of cirrhosis. ( Bartolí, R; Chatauret, N; Córdoba, J; Odena, G; Oria, M; Planas, R; Raguer, N, 2006)
"Hepatic encephalopathy is a syndrome characterized by increased blood ammonia level and is one of the major complications of cirrhosis."1.31The protective effect of HD-03 in CCl4-induced hepatic encephalopathy in rats. ( Anturlikar, SD; Gopumadhavan, S; Mitra, SK; Seshadri, SJ; Venkataranganna, MV; Venkatesha Udupa, U, 2001)
"Accompanying the hepatic encephalopathy were hematemesis, abdominal dropsy, and hyperammonemia, conditions observed in hepatic coma patients."1.27Blood ammonia levels and hepatic encephalopathy induced by CCl4 in rats. ( Sugihara, N; Yamamoto, H, 1987)
"During hepatic coma, the K+-stimulated [3H]GABA release was notably diminished in the striatum and cerebellum, whereas a significant increase was observed in the hippocampus."1.27Regional brain GABA metabolism and release during hepatic coma produced in rats chronically treated with carbon tetrachloride. ( Díaz-Muñoz, M; Tapia, R, 1988)
"This results in deep hepatic coma over a narrowly predictable time span and death within 12-52 h."1.27A predictable pathophysiological model of porcine hepatic failure. ( Alp, MH; Hickman, R, 1986)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199015 (68.18)18.7374
1990's2 (9.09)18.2507
2000's2 (9.09)29.6817
2010's3 (13.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Manzhaliy, EG1
Virchenko, OV1
Falaleyeva, TM1
Beregova, TV1
Savchuk, OM1
Kondratyuk, VE1
Miquel, M1
Bartolí, R2
Odena, G2
Serafín, A1
Cabré, E1
Galan, A1
Barba, I1
Córdoba, J2
Planas, R2
Chang, HM1
Liao, YW1
Chiang, CH1
Chen, YJ1
Lai, YH1
Chang, YL1
Chen, HL1
Jeng, SY1
Hsieh, JH1
Peng, CH1
Li, HY1
Chien, Y1
Chen, SY1
Chen, LK1
Huo, TI1
PATTON, TB1
LOMBARDO, CR1
LYONS, C1
MONDEN, M1
CORNELIUS, CE1
GAZMURI, G1
GRONWALL, R1
RHODE, EA1
Oria, M1
Raguer, N1
Chatauret, N1
Hayashi, S1
Sarafov, D1
Mitkov, D1
Dzhambazova, S1
Mitra, SK1
Venkataranganna, MV1
Gopumadhavan, S1
Anturlikar, SD1
Seshadri, SJ1
Venkatesha Udupa, U1
Diemer, NH1
Yamamoto, H2
Díaz-Muñoz, M2
Tapia, R2
Mullen, KD1
McCullough, AJ1
Sugihara, N2
Yamamoto, HA1
Bengtsson, F1
Bugge, M1
Vagianos, C1
Jeppsson, B1
Nobin, A1
Alp, MH2
Hickman, R3
Ito, M1
Matsumoto, H1
Kikuchi, S1
Yachi, A1
van Leenhoff, JA1
Saunders, SJ1
Terblanche, J1

Other Studies

22 other studies available for carbon tetrachloride and Hepatic Encephalopathy

ArticleYear
    Klinichna khirurhiia, 2016, Issue:10

    Topics: Animals; Carbon Tetrachloride; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expre

2016
Rat CCl(4)-induced cirrhosis plus total portal vein ligation: a new model for the study of hyperammonaemia and brain oedema.
    Liver international : official journal of the International Association for the Study of the Liver, 2010, Volume: 30, Issue:7

    Topics: Animals; Ascites; Biomarkers; Brain; Brain Edema; Carbon Tetrachloride; Disease Models, Animal; Endo

2010
Improvement of carbon tetrachloride-induced acute hepatic failure by transplantation of induced pluripotent stem cells without reprogramming factor c-Myc.
    International journal of molecular sciences, 2012, Volume: 13, Issue:3

    Topics: Animals; Antioxidants; Carbon Tetrachloride; Cell Differentiation; Cell Survival; Cell- and Tissue-B

2012
Experimental observations on meat intoxication, ammonia accumulation and hepatic coma.
    Annals of surgery, 1956, Volume: 143, Issue:5

    Topics: Amidohydrolases; Ammonia; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Hepatic Encephalopat

1956
[A STUDY OF THE FREE AMINO ACIDS IN THE SERUM OF LIVER DISEASES].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1964, May-10, Volume: 53

    Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Blood; Carbon Tetrachloride; Chemical and Drug Ind

1964
PRELIMINARY STUDIES ON EXPERIMENTAL HYPERBILIRUBINEMIA AND HEPATIC COMA IN THE HORSE.
    The Cornell veterinarian, 1965, Volume: 55

    Topics: Ammonia; Animals; Blood Chemical Analysis; Carbon Tetrachloride; Chemical and Drug Induced Liver Inj

1965
Functional abnormalities of the motor tract in the rat after portocaval anastomosis and after carbon tetrachloride induction of cirrhosis.
    Metabolic brain disease, 2006, Volume: 21, Issue:4

    Topics: Anastomosis, Surgical; Anesthetics, Intravenous; Animals; Carbon Tetrachloride; Disease Models, Anim

2006
Experimental studies on nutrition management in liver injury.
    Acta medica Okayama, 1983, Volume: 37, Issue:2

    Topics: Alanine Transaminase; Amino Acids, Branched-Chain; Animals; Carbon Tetrachloride; Enteral Nutrition;

1983
Effect of a balanced amino acid-based diet on the nitrogen metabolism in carbon tetrachloride-induced liver injury.
    Folia medica, 1994, Volume: 36, Issue:1

    Topics: Amino Acids, Branched-Chain; Animals; Brain; Carbon Tetrachloride; Hepatic Encephalopathy; Liver Cir

1994
The protective effect of HD-03 in CCl4-induced hepatic encephalopathy in rats.
    Phytotherapy research : PTR, 2001, Volume: 15, Issue:6

    Topics: Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Astrocytes; Carbon Tetrachlorid

2001
Size and density of oligodendroglial nuclei in rats with CCl4-induced liver disease.
    Neurobiology, 1975, Volume: 5, Issue:4

    Topics: Animals; Brain; Carbon Tetrachloride; Cell Division; Cell Nucleus; Corpus Callosum; Hepatic Encephal

1975
Brain phenylalanine and tyrosine levels and hepatic encephalopathy induced by CCl4 in rats.
    Toxicology, 1990, Apr-30, Volume: 61, Issue:3

    Topics: 2,4-Dinitrophenol; Amino Acids; Ammonium Chloride; Animals; Brain; Brain Chemistry; Carbon Tetrachlo

1990
Functional changes of brain mitochondria during experimental hepatic encephalopathy.
    Biochemical pharmacology, 1989, Nov-01, Volume: 38, Issue:21

    Topics: Adenosine Triphosphatases; Ammonia; Animals; Brain Chemistry; Carbon Tetrachloride; Cytochromes; Fat

1989
Problems with animal models of chronic liver disease: suggestions for improvement in standardization.
    Hepatology (Baltimore, Md.), 1989, Volume: 9, Issue:3

    Topics: Animals; Behavior, Animal; Carbon Tetrachloride; Chronic Disease; Disease Models, Animal; Hepatic En

1989
Blood ammonia levels and hepatic encephalopathy induced by CCl4 in rats.
    Toxicology and applied pharmacology, 1987, Volume: 91, Issue:3

    Topics: Adenosine Triphosphate; Ammonia; Animals; Argininosuccinate Synthase; Ca(2+) Mg(2+)-ATPase; Carbamoy

1987
Regional brain GABA metabolism and release during hepatic coma produced in rats chronically treated with carbon tetrachloride.
    Neurochemical research, 1988, Volume: 13, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Animals; Brain; Carbon Tetrachloride; gamma-Aminobutyric Acid; Glutama

1988
Hepatic ATP content and hyperammonemia induced by CCl4 in rats.
    Toxicology, 1988, Volume: 51, Issue:1

    Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Ammonia; Animals; Argininosuccinate Synthase; Carbamoyl-P

1988
Brain serotonin metabolism and behavior in rats with carbon tetrachloride-induced liver cirrhosis.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1987, Volume: 187, Issue:6

    Topics: Animals; Behavior, Animal; Brain; Carbon Tetrachloride; Exploratory Behavior; Hepatic Encephalopathy

1987
The effect of prostaglandins, branched-chain amino acids and other drugs on the outcome of experimental acute porcine hepatic failure.
    Journal of hepatology, 1987, Volume: 4, Issue:1

    Topics: Acetylcysteine; Amino Acids, Branched-Chain; Amino Acids, Essential; Animals; Carbon Tetrachloride;

1987
A predictable pathophysiological model of porcine hepatic failure.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1986, Volume: 18, Issue:5

    Topics: Amino Acids; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Disease Models, Animal; Hep

1986
[A comparative study of free amino acid levels in the serum and cerebral cortex in hepatic failure rats].
    No to shinkei = Brain and nerve, 1986, Volume: 38, Issue:1

    Topics: Acute Disease; Amino Acids; Ammonia; Animals; Blood-Brain Barrier; Carbon Tetrachloride; Cerebral Co

1986
Massive liver cell necrosis induced in the pig with carbon tetrachloride.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974, Jun-12, Volume: 48, Issue:28

    Topics: Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug

1974