carbon tetrachloride has been researched along with Experimental Hepatoma in 109 studies
Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of DEN-induced hepatocellular carcinoma Wistar rats with the extract caused significant (p < 0." | 5.56 | Annona senegalensis extract demonstrates anticancer properties in N-diethylnitrosamine-induced hepatocellular carcinoma in male Wistar rats. ( Adebayo, AH; Adelani, IB; Adesina, GO; Edokwe, CB; Metibemu, DS; Oseha, OE; Yakubu, OF, 2020) |
| "Metformin is a hypoglycaemic agent used to treat type 2 diabetes mellitus (DM2) patients, with a broad safety profile." | 5.51 | Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepatocellular carcinoma. ( Callegari, E; Gramantieri, L; Guerriero, P; Negrini, M; Pinton, P; Rimessi, A; Sabbioni, S; Shankaraiah, RC; Silini, EM, 2019) |
| " Here we describe a syngeneic orthotopic HCC model in immunocompetent mice with liver cirrhosis induced by carbon tetrachloride (CCl4) that recapitulates key features of human HCC." | 3.81 | An orthotopic mouse model of hepatocellular carcinoma with underlying liver cirrhosis. ( Bardeesy, N; Chen, Y; Duda, DG; Fan, C; Hato, T; Huang, P; Jain, RK; Lauwers, GY; Ramjiawan, RR; Reiberger, T; Roberge, S; Samuel, R; Zhu, AX, 2015) |
| "Hepatic tumors including hepatocellular carcinoma were generated by carbon tetrachloride in transgenic mice carrying a human c-H-ras gene (rasH2 mice)." | 3.69 | Role of H-ras gene in chronic liver damage in mice. By using transgenic mice carrying a human C-H-ras proto-oncogene without mutations. ( Ishii, H; Morizane, T; Saito, H; Sato, R; Tsunematsu, S, 1997) |
| " However, cytokeratin dimers and high-molecular-weight cytokeratin polymers were detected in liver tissue with histological evidence of coagulative necrosis induced by ischemia or carbon tetrachloride." | 3.68 | Cross-linked cytokeratin polypeptides in liver and hepatoma cells: possible association with the process of cell degeneration and death. ( Chiu, JF; Fukuda, K; Kojiro, M, 1993) |
| "TGF-β signaling links HSC activation to liver fibrosis and tumorigenesis." | 1.62 | Perivenous Stellate Cells Are the Main Source of Myofibroblasts and Cancer-Associated Fibroblasts Formed After Chronic Liver Injuries. ( Ge, G; Lin, M; Peng, YJ; Ren, Z; Shang, G; Tang, XT; Wang, SS; Yin, X; Yuan, J; Zhou, BO, 2021) |
| "Treatment of DEN-induced hepatocellular carcinoma Wistar rats with the extract caused significant (p < 0." | 1.56 | Annona senegalensis extract demonstrates anticancer properties in N-diethylnitrosamine-induced hepatocellular carcinoma in male Wistar rats. ( Adebayo, AH; Adelani, IB; Adesina, GO; Edokwe, CB; Metibemu, DS; Oseha, OE; Yakubu, OF, 2020) |
| "Metformin is a hypoglycaemic agent used to treat type 2 diabetes mellitus (DM2) patients, with a broad safety profile." | 1.51 | Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepatocellular carcinoma. ( Callegari, E; Gramantieri, L; Guerriero, P; Negrini, M; Pinton, P; Rimessi, A; Sabbioni, S; Shankaraiah, RC; Silini, EM, 2019) |
| " Therefore, the effects of the orally bioavailable synthetic triterpenoid 2-cyano-3,12-dioxooleana- 1,9(11)-dien-28-oate-ethyl amide (CDDO-EA, RTA 405), which has potent antioxidative and antiinflammatory properties, was evaluated in a chronic carbon tetrachloride (CCl(4))-induced model of liver cirrhosis and hepatocellular carcinoma (HCC)." | 1.43 | The Synthetic Triterpenoid RTA 405 (CDDO-EA) Halts Progression of Liver Fibrosis and Reduces Hepatocellular Carcinoma Size Resulting in Increased Survival in an Experimental Model of Chronic Liver Injury. ( Cusimano, FA; Getachew, Y; Gopal, P; Reisman, SA; Shay, JW, 2016) |
| "Hepatocarcinogenesis was significantly accelerated in the fibrotic livers compared to those of the control, significantly decreasing the life span of the mice." | 1.43 | Development of a transgenic mouse model of hepatocellular carcinoma with a liver fibrosis background. ( Ahn, SH; Cho, KJ; Chung, SI; Han, KH; Ju, HL; Kim, DY; Moon, H; Ro, SW, 2016) |
| "Human hepatocellular carcinoma (HCC) develops most often as a complication of fibrosis or cirrhosis." | 1.40 | The DEN and CCl4 -Induced Mouse Model of Fibrosis and Inflammation-Associated Hepatocellular Carcinoma. ( Pogribny, IP; Rusyn, I; Uehara, T, 2014) |
| "Hepatocellular carcinoma was induced by single intraperitoneal injection of N-nitrosodiethylamine (NDEA) in normal saline at a dose of 200 mg/kg body weight followed by weekly subcutaneous injections of CCl(4)(3 mL/kg/week) for 6 weeks, as the promoter of carcinogenic effect." | 1.38 | Evaluation of chemopreventive effect of Fumaria indica against N-nitrosodiethylamine and CCl4-induced hepatocellular carcinoma in Wistar rats. ( Fareed, S; Hussain, T; Rao, CV; Siddiqui, HH; Vijayakumar, M, 2012) |
| "Carbon tetrachloride was given by subcutaneous (s." | 1.31 | Role of oxidative DNA damage caused by carbon tetrachloride-induced liver injury -- enhancement of MeIQ-induced glutathione S-transferase placental form-positive foci in rats. ( Fukushima, S; Iwai, S; Karim, R; Kitano, M; Min, W; Morimura, K; Seki, S; Sukata, T; Wanibuchi, H, 2002) |
| "Transforming growth factor beta1 (TGF-beta1) has been implicated as inhibitor of cell proliferation and a potent inducer of apoptosis in vitro and in vivo after the administration of high doses." | 1.30 | Levels of transforming growth factor beta and transforming growth factor beta receptors in rat liver during growth, regression by apoptosis and neoplasia. ( Bursch, W; Grasl-Kraupp, B; Kammerer, B; Müllauer, L; Rossmanith, W; Ruttkay-Nedecky, B; Schulte-Hermann, R, 1998) |
| " Treatment with CCl4 after AFB1 dosing lowered hepatic GSH levels by 20% and increased lipid peroxidation by 40%." | 1.30 | Enhancement of aflatoxin B1-induced enzyme altered hepatic foci in rats by treatment with carbon tetrachloride. ( Lotlikar, PD; Ning, Y; Qin, G; Shinozuka, H; Su, J, 1998) |
| " This demonstrates that chronic administration of an exogenous compound is not the only way to promote cancer development." | 1.27 | [Promoting effect of portacaval anastomosis in experimental hepatic carcinogenesis]. ( de Gerlache, J; Lans, M; Pector, JC; Préat, V; Roberfroid, M; Taper, H, 1984) |
| "In diethylnitrosamine (DEN)-treated rats, which were fed a N-2-fluorenylacetamide (FAA)-containing diet and additionally treated with repeated CCl4 injections, gamma-glutamyl transpeptidase (gamma-GTP)-positive hyperplastic nodules were markedly developed in the 8th week of the experiment." | 1.27 | Effects of carbon tetrachloride and azathioprine on diethylnitrosamine and N-2-fluorenylacetamide-induced hyperplastic liver nodule and hepatocellular carcinoma. ( Sakata, T, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (30.28) | 18.7374 |
| 1990's | 29 (26.61) | 18.2507 |
| 2000's | 19 (17.43) | 29.6817 |
| 2010's | 24 (22.02) | 24.3611 |
| 2020's | 4 (3.67) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, C | 2 |
| Yang, Y | 1 |
| Chen, C | 1 |
| Li, L | 2 |
| Li, J | 1 |
| Wang, X | 1 |
| Chu, Q | 1 |
| Qiu, L | 1 |
| Ba, Q | 1 |
| Li, X | 1 |
| Wang, H | 2 |
| Shankaraiah, RC | 1 |
| Callegari, E | 1 |
| Guerriero, P | 1 |
| Rimessi, A | 1 |
| Pinton, P | 1 |
| Gramantieri, L | 1 |
| Silini, EM | 1 |
| Sabbioni, S | 1 |
| Negrini, M | 1 |
| Lin, YH | 1 |
| Zhang, S | 1 |
| Zhu, M | 1 |
| Lu, T | 1 |
| Chen, K | 1 |
| Wen, Z | 1 |
| Wang, S | 1 |
| Xiao, G | 1 |
| Luo, D | 1 |
| Jia, Y | 1 |
| MacConmara, M | 1 |
| Hoshida, Y | 1 |
| Singal, AG | 1 |
| Yopp, A | 1 |
| Wang, T | 1 |
| Zhu, H | 1 |
| Yakubu, OF | 1 |
| Metibemu, DS | 1 |
| Adelani, IB | 1 |
| Adesina, GO | 1 |
| Edokwe, CB | 1 |
| Oseha, OE | 1 |
| Adebayo, AH | 1 |
| Wang, SS | 1 |
| Tang, XT | 1 |
| Lin, M | 1 |
| Yuan, J | 1 |
| Peng, YJ | 1 |
| Yin, X | 1 |
| Shang, G | 1 |
| Ge, G | 1 |
| Ren, Z | 1 |
| Zhou, BO | 1 |
| Ali, MM | 1 |
| H Borai, I | 1 |
| Ghanem, HM | 1 |
| H Abdel-Halim, A | 1 |
| Mousa, FM | 1 |
| Wu, Q | 1 |
| Chen, JX | 1 |
| Chen, Y | 2 |
| Cai, LL | 1 |
| Wang, XZ | 1 |
| Guo, WH | 1 |
| Zheng, JF | 1 |
| Romualdo, GR | 1 |
| Prata, GB | 1 |
| da Silva, TC | 1 |
| Fernandes, AAH | 1 |
| Moreno, FS | 1 |
| Cogliati, B | 1 |
| Barbisan, LF | 1 |
| Iwako, H | 1 |
| Tashiro, H | 1 |
| Okimoto, S | 1 |
| Yamaguchi, M | 1 |
| Abe, T | 1 |
| Kuroda, S | 1 |
| Kobayashi, T | 1 |
| Ohdan, H | 1 |
| Liu, XQ | 1 |
| Hu, XJ | 1 |
| Xu, HX | 1 |
| Zeng, XY | 1 |
| Uehara, T | 3 |
| Pogribny, IP | 3 |
| Rusyn, I | 3 |
| Ray, S | 1 |
| Murmu, N | 1 |
| Adhikari, J | 1 |
| Bhattacharyya, S | 1 |
| Adhikari, S | 1 |
| Banerjee, S | 1 |
| Marrone, AK | 1 |
| Shpyleva, S | 1 |
| Chappell, G | 1 |
| Tryndyak, V | 1 |
| Tsuchiya, M | 2 |
| Beland, FA | 1 |
| Reiberger, T | 1 |
| Ramjiawan, RR | 1 |
| Hato, T | 1 |
| Fan, C | 1 |
| Samuel, R | 1 |
| Roberge, S | 1 |
| Huang, P | 1 |
| Lauwers, GY | 1 |
| Zhu, AX | 1 |
| Bardeesy, N | 1 |
| Jain, RK | 1 |
| Duda, DG | 1 |
| Mu, X | 1 |
| Español-Suñer, R | 1 |
| Mederacke, I | 1 |
| Affò, S | 1 |
| Manco, R | 1 |
| Sempoux, C | 1 |
| Lemaigre, FP | 1 |
| Adili, A | 1 |
| Yuan, D | 1 |
| Weber, A | 2 |
| Unger, K | 1 |
| Heikenwälder, M | 2 |
| Leclercq, IA | 1 |
| Schwabe, RF | 2 |
| Getachew, Y | 1 |
| Cusimano, FA | 1 |
| Gopal, P | 1 |
| Reisman, SA | 1 |
| Shay, JW | 1 |
| Li, W | 1 |
| Xiao, J | 1 |
| Zhou, X | 1 |
| Xu, M | 1 |
| Hu, C | 1 |
| Xu, X | 1 |
| Lu, Y | 1 |
| Xue, S | 1 |
| Nie, L | 1 |
| Zhang, H | 3 |
| Li, Z | 1 |
| Zhang, Y | 1 |
| Ji, F | 1 |
| Hui, L | 1 |
| Tao, W | 1 |
| Wei, B | 1 |
| Chung, SI | 1 |
| Moon, H | 1 |
| Kim, DY | 2 |
| Cho, KJ | 2 |
| Ju, HL | 1 |
| Ahn, SH | 1 |
| Han, KH | 1 |
| Ro, SW | 1 |
| Matter, MS | 1 |
| Marquardt, JU | 1 |
| Andersen, JB | 1 |
| Quintavalle, C | 1 |
| Korokhov, N | 1 |
| Stauffer, JK | 1 |
| Kaji, K | 1 |
| Decaens, T | 1 |
| Quagliata, L | 1 |
| Elloumi, F | 1 |
| Hoang, T | 1 |
| Molinolo, A | 1 |
| Conner, EA | 1 |
| Factor, VM | 1 |
| Thorgeirsson, SS | 1 |
| Aboubakr, EM | 1 |
| Taye, A | 1 |
| Aly, OM | 1 |
| Gamal-Eldeen, AM | 1 |
| El-Moselhy, MA | 1 |
| Beer, S | 1 |
| Komatsubara, K | 1 |
| Bellovin, DI | 1 |
| Kurobe, M | 1 |
| Sylvester, K | 1 |
| Felsher, DW | 1 |
| Xie, YA | 1 |
| Kuang, ZP | 1 |
| Liang, AM | 1 |
| Luo, XL | 1 |
| Yang, F | 1 |
| Wu, JN | 1 |
| Singh, BN | 1 |
| Singh, BR | 1 |
| Sarma, BK | 1 |
| Singh, HB | 1 |
| Xu, XB | 3 |
| He, ZP | 3 |
| Leng, XS | 3 |
| Liang, ZQ | 1 |
| Peng, JR | 1 |
| Zhang, HY | 4 |
| Xiao, M | 2 |
| Liu, CL | 2 |
| Zhang, XD | 1 |
| Chen, L | 2 |
| Feng, ZQ | 1 |
| Kluwe, J | 1 |
| Wongsiriroj, N | 1 |
| Troeger, JS | 1 |
| Gwak, GY | 1 |
| Dapito, DH | 1 |
| Pradere, JP | 1 |
| Jiang, H | 1 |
| Siddiqi, M | 1 |
| Piantedosi, R | 1 |
| O'Byrne, SM | 1 |
| Blaner, WS | 1 |
| Maeda, M | 1 |
| Takami, T | 1 |
| Terai, S | 1 |
| Sakaida, I | 1 |
| Abdel-Hamid, NM | 1 |
| Abdel-Ghany, MI | 1 |
| Nazmy, MH | 1 |
| Amgad, SW | 1 |
| Hussain, T | 1 |
| Siddiqui, HH | 1 |
| Fareed, S | 1 |
| Vijayakumar, M | 1 |
| Rao, CV | 1 |
| Hayashi, H | 1 |
| Taniai, E | 1 |
| Morita, R | 1 |
| Hayashi, M | 1 |
| Nakamura, D | 1 |
| Wakita, A | 1 |
| Suzuki, K | 1 |
| Shibutani, M | 1 |
| Mitsumori, K | 2 |
| Ainslie, GR | 1 |
| Kutanzi, K | 1 |
| Muskhelishvili, L | 1 |
| Izawa, T | 1 |
| Yamate, J | 1 |
| Kosyk, O | 1 |
| Shymonyak, S | 1 |
| Bradford, BU | 1 |
| Boorman, GA | 1 |
| Bataller, R | 1 |
| Moto, M | 1 |
| Sasaki, YF | 1 |
| Okamura, M | 1 |
| Fujita, M | 1 |
| Kashida, Y | 1 |
| Machida, N | 1 |
| ANDERVONT, HB | 1 |
| MALTONI, C | 1 |
| PRODI, G | 1 |
| CHAN, P | 1 |
| McDONALD, GO | 1 |
| COLE, WH | 1 |
| DELLA PORTA, G | 2 |
| TERRACINI, B | 1 |
| SHUBIK, P | 1 |
| PODZEI, LK | 2 |
| Espandiari, P | 1 |
| Glauert, HP | 1 |
| Lehmler, HJ | 1 |
| Lee, EY | 1 |
| Srinivasan, C | 1 |
| Robertson, LW | 1 |
| Bull, RJ | 1 |
| Sasser, LB | 1 |
| Lei, XC | 1 |
| Yang, X | 1 |
| Aziz, TA | 1 |
| Aziz, MA | 1 |
| Fouad, HH | 1 |
| Rashed, LA | 1 |
| Salama, H | 1 |
| Abd-Alla, S | 1 |
| Wehab, MA | 1 |
| Ahmed, T | 1 |
| Ma, W | 1 |
| Xia, X | 1 |
| Stafford, LJ | 1 |
| Yu, C | 1 |
| Wang, F | 1 |
| LeSage, G | 1 |
| Liu, M | 1 |
| Tessitore, L | 2 |
| Bollito, E | 1 |
| Farazi, PA | 1 |
| Glickman, J | 1 |
| Horner, J | 1 |
| Depinho, RA | 1 |
| Kuhlmann, WD | 1 |
| Peschke, P | 1 |
| Dakshayani, KB | 1 |
| Subramanian, P | 1 |
| Manivasagam, T | 1 |
| Mohamed Essa, M | 1 |
| Naugler, WE | 1 |
| Sakurai, T | 1 |
| Kim, S | 1 |
| Maeda, S | 1 |
| Kim, K | 1 |
| Elsharkawy, AM | 1 |
| Karin, M | 1 |
| Tsujimura, K | 1 |
| Ichinose, F | 1 |
| Hara, T | 1 |
| Yamasaki, K | 1 |
| Otsuka, M | 1 |
| Fukushima, S | 2 |
| Sakata, T | 2 |
| Watanabe, A | 2 |
| Takei, N | 1 |
| Shiota, T | 1 |
| Nakatsukasa, H | 1 |
| Fujiwara, M | 1 |
| Kobayashi, M | 2 |
| Nagashima, H | 1 |
| Préat, V | 3 |
| Pector, JC | 1 |
| Taper, H | 2 |
| de Gerlache, J | 2 |
| Lans, M | 2 |
| Roberfroid, M | 3 |
| Poli, G | 1 |
| Chiarpotto, E | 1 |
| Gravela, E | 1 |
| Laurier, C | 1 |
| Tatematsu, M | 1 |
| Rao, PM | 2 |
| Rajalakshmi, S | 2 |
| Sarma, DS | 3 |
| Sidransky, H | 1 |
| Verney, E | 1 |
| Bassi, A | 1 |
| Rossi, MA | 1 |
| Ferro, M | 1 |
| Wang, GM | 1 |
| Van Goethem, F | 2 |
| de Stoppelaar, J | 1 |
| Hoebee, B | 1 |
| Kirsch-Volders, M | 3 |
| Fukuda, K | 2 |
| Kojiro, M | 2 |
| Chiu, JF | 2 |
| Tsunematsu, S | 2 |
| Saito, H | 2 |
| Kagawa, T | 1 |
| Morizane, T | 2 |
| Hata, J | 1 |
| Nakamura, T | 1 |
| Ishii, H | 2 |
| Nomura, T | 1 |
| Katsuki, M | 1 |
| Zalatnai, A | 5 |
| Lapis, K | 5 |
| Ghahroudi, MA | 1 |
| Castelain, P | 2 |
| Fanelli, SL | 1 |
| Castro, JA | 1 |
| Jang, JJ | 1 |
| Kobliakov, V | 1 |
| Kulikova, L | 1 |
| Samoilov, D | 1 |
| Lang, MA | 1 |
| Frezza, EE | 1 |
| Gerunda, GE | 1 |
| Farinati, F | 1 |
| Plebani, M | 1 |
| Giacomin, A | 1 |
| Galligioni, A | 1 |
| Neri, D | 1 |
| Merenda, R | 1 |
| Toniolo, E | 1 |
| De Maria, N | 1 |
| Kelly, JD | 1 |
| Dutchuk, M | 1 |
| Hendricks, JD | 1 |
| Williams, DE | 1 |
| Columbano, A | 4 |
| Endoh, T | 1 |
| Denda, A | 1 |
| Noguchi, O | 1 |
| Nakae, D | 1 |
| Hasegawa, K | 1 |
| Ledda-Columbano, GM | 4 |
| Zedda, AI | 1 |
| Konishi, Y | 1 |
| Hiruma, S | 1 |
| Qin, GZ | 1 |
| Gopalan-Kriczky, P | 1 |
| Shinozuka, H | 2 |
| Sato, K | 1 |
| Lotlikar, PD | 3 |
| Sato, R | 1 |
| Grasl-Kraupp, B | 1 |
| Rossmanith, W | 1 |
| Ruttkay-Nedecky, B | 1 |
| Müllauer, L | 1 |
| Kammerer, B | 1 |
| Bursch, W | 1 |
| Schulte-Hermann, R | 1 |
| Qin, G | 2 |
| Ning, Y | 2 |
| Su, J | 1 |
| Wang, GS | 1 |
| Eriksson, LC | 1 |
| Xia, L | 1 |
| Olsson, J | 1 |
| Stål, P | 1 |
| Yusuf, A | 1 |
| Sawada, S | 1 |
| Murakami, K | 1 |
| Murata, J | 1 |
| Tsukada, K | 1 |
| Saiki, I | 1 |
| Reuber, MD | 1 |
| Glover, EL | 1 |
| Iwai, S | 1 |
| Karim, R | 1 |
| Kitano, M | 1 |
| Sukata, T | 1 |
| Min, W | 1 |
| Morimura, K | 1 |
| Wanibuchi, H | 1 |
| Seki, S | 1 |
| Martínez-Chantar, ML | 1 |
| Corrales, FJ | 1 |
| Martínez-Cruz, LA | 1 |
| García-Trevijano, ER | 1 |
| Huang, ZZ | 1 |
| Kanel, G | 1 |
| Avila, MA | 1 |
| Mato, JM | 1 |
| Lu, SC | 1 |
| Petzinger, E | 1 |
| Ziegler, K | 1 |
| Frimmer, M | 1 |
| Belokhvostov, AS | 1 |
| Zelenkova, NK | 1 |
| Coni, P | 3 |
| Curto, M | 1 |
| Giacomini, L | 1 |
| Faa, G | 1 |
| Kovalszky, I | 1 |
| Szeberenyi, S | 1 |
| Vincze, I | 1 |
| Jeney, A | 1 |
| Pani, P | 3 |
| Dianzani, MU | 1 |
| Gelderblom, WC | 1 |
| Semple, E | 1 |
| Marasas, WF | 1 |
| Farber, E | 1 |
| Sone, H | 1 |
| Wakabayashi, K | 1 |
| Kushida, H | 1 |
| Sugimura, T | 1 |
| Nagao, M | 1 |
| Kotsanis, N | 1 |
| Metcalfe, CD | 1 |
| Lertprasertsuke, N | 1 |
| Shinoda, M | 1 |
| Takekoshi, S | 1 |
| Tsutsumi, Y | 1 |
| Yamamoto, Y | 1 |
| Niki, E | 1 |
| Watanabe, K | 1 |
| Cunningham, ML | 1 |
| Matthews, HB | 1 |
| Sárosi, I | 1 |
| Rot, A | 1 |
| Lapsis, K | 1 |
| Abdellatif, AG | 1 |
| Vamecq, J | 1 |
| Nilsson, R | 1 |
| Petropoulos, CJ | 1 |
| Yaswen, P | 1 |
| Panzica, M | 1 |
| Fausto, N | 1 |
| Deleener, A | 1 |
| Barbason, H | 1 |
| Richardson, FC | 1 |
| Boucheron, JA | 1 |
| Dyroff, MC | 1 |
| Popp, JA | 1 |
| Swenberg, JA | 1 |
| Yamauchi, Y | 1 |
| Liguori, C | 1 |
| Martelli, A | 1 |
| Ghia, M | 1 |
| Mereto, E | 1 |
| Marinari, UM | 1 |
| Brambilla, G | 1 |
| Katsukura, Y | 1 |
| Abe, N | 1 |
| Watabe, N | 1 |
| Tsuchiya, T | 1 |
| Tanaka, T | 1 |
| Mori, H | 1 |
| Williams, GM | 1 |
| Tsuda, H | 1 |
| Masui, T | 1 |
| Ikawa, E | 1 |
| Imaida, K | 1 |
| Ito, N | 1 |
| Dragani, TA | 1 |
| Manenti, G | 1 |
| Becker, RA | 1 |
| Planche-Martel, G | 1 |
| Andersen, O | 1 |
| Lindegaard, P | 1 |
| Unger, M | 1 |
| Nordberg, GF | 1 |
| Lombardi, B | 1 |
| Ove, P | 1 |
| Reddy, TV | 1 |
1 trial available for carbon tetrachloride and Experimental Hepatoma
| Article | Year |
|---|---|
Can methanolic extract of Nigella sativa seed affect glyco-regulatory enzymes in experimental hepatocellular carcinoma?
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Carbon Tetrachloride; Carcinoma, Hepa | 2013 |
108 other studies available for carbon tetrachloride and Experimental Hepatoma
| Article | Year |
|---|---|
Environmental eustress modulates β-ARs/CCL2 axis to induce anti-tumor immunity and sensitize immunotherapy against liver cancer in mice.
Topics: Animals; B7-H1 Antigen; Carbon Tetrachloride; Chemokine CCL2; Diethylnitrosamine; Drug Resistance, N | 2021 |
Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepatocellular carcinoma.
Topics: Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Disease M | 2019 |
Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity But Develop Fewer Hepatocellular Carcinomas Following Chronic Liver Injury.
Topics: Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cells, Cultured; Chemical and Drug Induced | 2020 |
Annona senegalensis extract demonstrates anticancer properties in N-diethylnitrosamine-induced hepatocellular carcinoma in male Wistar rats.
Topics: Animals; Annona; Antineoplastic Agents, Phytogenic; Antioxidants; Carbon Tetrachloride; Carcinoma, H | 2020 |
Perivenous Stellate Cells Are the Main Source of Myofibroblasts and Cancer-Associated Fibroblasts Formed After Chronic Liver Injuries.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Bile Ducts; Cancer-Associated Fibroblasts; Ca | 2021 |
The prophylactic and therapeutic effects of Momordica charantia methanol extract through controlling different hallmarks of the hepatocarcinogenesis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carbon Tetrachloride; Carcinogenesis; Cell Proliferation; | 2018 |
The chemokine receptor CCR10 promotes inflammation-driven hepatocarcinogenesis via PI3K/Akt pathway activation.
Topics: Adolescent; Adult; Aged; Animals; Apoptosis; Carbon Tetrachloride; Carcinogenesis; Carcinoma, Hepato | 2018 |
Fibrosis-associated hepatocarcinogenesis revisited: Establishing standard medium-term chemically-induced male and female models.
Topics: Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Diethylnitrosamine; Disease Susceptibility | 2018 |
Antithrombin Insufficiency Promotes Susceptibility to Liver Tumorigenesis.
Topics: Animals; Antithrombin III; Carbon Tetrachloride; Carcinoma, Hepatocellular; Diethylnitrosamine; Fema | 2019 |
Xiaochaihu Decoction attenuates the vicious circle between the oxidative stress and the ALP inactivation through LPS-catecholamines interactions in gut, liver and brain during CCI4+ethanol-induced mouse HCC.
Topics: Alkaline Phosphatase; Animals; Brain; Brain Chemistry; Carbon Tetrachloride; Catecholamines; Drug St | 2013 |
The DEN and CCl4 -Induced Mouse Model of Fibrosis and Inflammation-Associated Hepatocellular Carcinoma.
Topics: Animals; Carbon Tetrachloride; Carcinogens; Carcinoma, Hepatocellular; Chemical and Drug Induced Liv | 2014 |
Inhibition of Hep G2 hepatic cancer cell growth and CCl₄ induced liver cytotoxicity in Swiss albino mice by Mahua extract.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Cell Proliferation; Female; Flowers; Gene Expression Re | 2014 |
Differentially expressed MicroRNAs provide mechanistic insight into fibrosis-associated liver carcinogenesis in mice.
Topics: Animals; Carbon Tetrachloride; Cell Line, Tumor; Diethylnitrosamine; Gene Expression Profiling; Gene | 2016 |
An orthotopic mouse model of hepatocellular carcinoma with underlying liver cirrhosis.
Topics: Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Liver Cirrhosis; Liver Neoplasms; Liver Ne | 2015 |
Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment.
Topics: alpha-Fetoproteins; Animals; Bile Ducts; Biomarkers, Tumor; Carbon Tetrachloride; Carcinogens; Cell | 2015 |
The Synthetic Triterpenoid RTA 405 (CDDO-EA) Halts Progression of Liver Fibrosis and Reduces Hepatocellular Carcinoma Size Resulting in Increased Survival in an Experimental Model of Chronic Liver Injury.
Topics: Animals; Carbon Tetrachloride; Cell Line, Tumor; Cytochrome P-450 CYP2E1; Cytokines; Disease Progres | 2016 |
STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.
Topics: Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cytokines; Diethylnitrosamine; Escherichia | 2015 |
Development of a transgenic mouse model of hepatocellular carcinoma with a liver fibrosis background.
Topics: Animals; Carbon Tetrachloride; Carcinogenesis; Carcinoma, Hepatocellular; Disease Models, Animal; Ge | 2016 |
Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype.
Topics: Adaptor Proteins, Signal Transducing; Animals; beta Catenin; Carbon Tetrachloride; Cell Line; Chemok | 2016 |
Enhanced anticancer effect of Combretastatin A-4 phosphate when combined with vincristine in the treatment of hepatocellular carcinoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biomarke | 2017 |
Hepatotoxin-induced changes in the adult murine liver promote MYC-induced tumorigenesis.
Topics: Animals; Base Sequence; Blotting, Western; Carbon Tetrachloride; Carcinogens; Dicarbethoxydihydrocol | 2008 |
[Dendritic cell vaccine modified by murine mAFP gene enhances immunoprotective effect on liver carcinogenesis and tumor development in mice].
Topics: Adenoviridae; alpha-Fetoproteins; Animals; B7-1 Antigen; Cancer Vaccines; Carbon Tetrachloride; Cell | 2008 |
Potential chemoprevention of N-nitrosodiethylamine-induced hepatocarcinogenesis by polyphenolics from Acacia nilotica bark.
Topics: Acacia; Animals; Biomarkers, Tumor; Body Weight; Carbon Tetrachloride; Carcinogens; Diethylnitrosami | 2009 |
[Effects of Smad4 on liver fibrosis and hepatocarcinogenesis in mice treated with CCl4/ethanol].
Topics: Animals; Carbon Tetrachloride; Disease Models, Animal; Ethanol; Female; Liver Cirrhosis, Experimenta | 2010 |
[Observation on experimental liver fibrosis and hepatic carcinogenesis of HBV gene knock-in transgenic mice induced by CCl4/ethanol].
Topics: Animals; Carbon Tetrachloride; Disease Models, Animal; Ethanol; Female; Gene Knock-In Techniques; He | 2010 |
Absence of hepatic stellate cell retinoid lipid droplets does not enhance hepatic fibrosis but decreases hepatic carcinogenesis.
Topics: Acyltransferases; Animals; Carbon Tetrachloride; Cell Transformation, Neoplastic; Cells, Cultured; D | 2011 |
Autologous bone marrow cell infusions suppress tumor initiation in hepatocarcinogenic mice with liver cirrhosis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Bone Marrow Transplantation; Carbon Tetrachloride; Carcinoma, | 2012 |
Evaluation of chemopreventive effect of Fumaria indica against N-nitrosodiethylamine and CCl4-induced hepatocellular carcinoma in Wistar rats.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Body Weight; Carbon Tetrachloride; Ca | 2012 |
Enhanced liver tumor promotion but not liver initiation activity in rats subjected to combined administration of omeprazole and β-naphthoflavone.
Topics: Animals; beta-Naphthoflavone; Carbon Tetrachloride; Carcinogens; Cyclooxygenase 2; Cytochrome P-450 | 2012 |
Molecular mechanisms of fibrosis-associated promotion of liver carcinogenesis.
Topics: Animals; Animals, Newborn; Carbon Tetrachloride; Cell Transformation, Neoplastic; Diethylnitrosamine | 2013 |
Absence of in vivo genotoxicity and liver initiation activity of dicyclanil.
Topics: Administration, Oral; Animals; Carbon Tetrachloride; Carcinogens; Comet Assay; Dose-Response Relatio | 2003 |
Induction of hepatomas in strain C3H mice with 4-o-tolyazoo-toluidine and carbon tetrachloride.
Topics: Aniline Compounds; Animals; Carbon Tetrachloride; Carcinogens; Carcinoma, Hepatocellular; Coloring A | 1958 |
Effect of cirrhogenic treatment with carbon tetrachloride on the development of liver neoplasia in rats fed with butter-yellow (p-dimethylaminoazobenzene).
Topics: Animals; Butter; Carbon Tetrachloride; Carcinogens; Liver Neoplasms; Liver Neoplasms, Experimental; | 1959 |
The role of hepatic damage on development of the Walker 256 carcinosarcoma.
Topics: Animals; Carbon Tetrachloride; Carcinoma 256, Walker; Liver; Liver Diseases; Liver Neoplasms, Experi | 1960 |
Induction with carbon tetrachloride of liver-cell carcinomas in hamsters.
Topics: Carbon Tetrachloride; Carcinoma, Hepatocellular; Liver Neoplasms; Liver Neoplasms, Experimental | 1961 |
[Metastasis of Brown-Pierce tumors transplanted into different sections of the stomach, in normal conditions and following the action on the liver of carbon tetrachloride].
Topics: Animals; Carbon Tetrachloride; Liver Neoplasms, Experimental; Neoplasms, Experimental; Stomach Neopl | 1961 |
Metastasis formation of Brown-Pearce tumor inoculated into different parts of the stomach under normal conditions and after exposure of the liver to carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Liver Neoplasms, Experimental; Neoplasms, Experimental; Stomach Neopl | 1961 |
Initiating activity of 4-chlorobiphenyl metabolites in the resistant hepatocyte model.
Topics: 2-Acetylaminofluorene; Adenoma, Liver Cell; Administration, Oral; Animals; Biphenyl Compounds; Body | 2004 |
Interactions in the tumor-promoting activity of carbon tetrachloride, trichloroacetate, and dichloroacetate in the liver of male B6C3F1 mice.
Topics: Administration, Oral; Animals; Carbon Tetrachloride; Carcinogens; Dichloroacetic Acid; Dose-Response | 2004 |
[Obstruction of TGF-beta1 signal transduction can decrease the process of hepatocellular carcinoma in mice induced by CCl4/ethanol].
Topics: Adenoviridae; Animals; Antisense Elements (Genetics); Carbon Tetrachloride; Cell Transformation, Neo | 2004 |
Interferon-alpha gene therapy prevents aflatoxin and carbon tetrachloride promoted hepatic carcinogenesis in rats.
Topics: Aflatoxins; Animals; Carbon Tetrachloride; Cell Line; Cell Transformation, Neoplastic; Disease Model | 2005 |
Expression of GCIP in transgenic mice decreases susceptibility to chemical hepatocarcinogenesis.
Topics: Animals; Carbon Tetrachloride; Carcinogens; Cell Line, Tumor; Female; Genetic Predisposition to Dise | 2006 |
Early induction of TGF-beta1 through a fasting-re-feeding regimen promotes liver carcinogenesis by a sub-initiating dose of diethylnitrosamine.
Topics: 2-Acetylaminofluorene; Animals; Apoptosis; bcl-2-Associated X Protein; Carbon Tetrachloride; Carcino | 2006 |
Cooperative interactions of p53 mutation, telomere dysfunction, and chronic liver damage in hepatocellular carcinoma progression.
Topics: Alleles; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Disease Models, Animal; Dise | 2006 |
Hepatic progenitor cells, stem cells, and AFP expression in models of liver injury.
Topics: alpha-Fetoproteins; Animals; Carbon Tetrachloride; Cell Differentiation; Cell Proliferation; Disease | 2006 |
Metabolic normalization of alpha-ketoglutarate against N-nitrosodiethylamine-induced hepatocarcinogenesis in rats.
Topics: Alanine Transaminase; Animals; Anticarcinogenic Agents; Aspartate Aminotransferases; Carbon Tetrachl | 2006 |
Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production.
Topics: Animals; Carbon Tetrachloride; Diethylnitrosamine; Estradiol; Female; Hepatocytes; Interleukin-6; Ku | 2007 |
The inhalation exposure of carbon tetrachloride promote rat liver carcinogenesis in a medium-term liver bioassay.
Topics: Animals; Biological Assay; Body Weight; Carbon Tetrachloride; Carcinogenicity Tests; Carcinogens; Do | 2008 |
Effect of azathioprine and carbon tetrachloride on induction of hyperplastic liver nodule and hepatocellular carcinoma by diethylnitrosamine and N-2-fluorenylacetamide in rats.
Topics: 2-Acetylaminofluorene; Aniline Hydroxylase; Animals; Azathioprine; Carbon Tetrachloride; Diethylnitr | 1983 |
[Promoting effect of portacaval anastomosis in experimental hepatic carcinogenesis].
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Diethylnitrosamine; Liver Neoplasms, Experimen | 1984 |
Effect of aldehydes on polyamine metabolism. III. Inhibition of S-adenosyl methionine decarboxylase (SAMD) by CCl4 and by aldehydes produced during lipid peroxidation.
Topics: Adenosylmethionine Decarboxylase; Aldehydes; Animals; Carbon Tetrachloride; Carboxy-Lyases; Lipid Pe | 1981 |
Effects of carbon tetrachloride and azathioprine on diethylnitrosamine and N-2-fluorenylacetamide-induced hyperplastic liver nodule and hepatocellular carcinoma.
Topics: 2-Acetylaminofluorene; Aniline Hydroxylase; Animals; Azathioprine; Carbon Tetrachloride; Diethylnitr | 1984 |
Promotion by orotic acid of liver carcinogenesis in rats initiated by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carbon Tetrachloride; Dimethylhydrazines; Liver Neoplasms, Experimen | 1984 |
Acute effects of selected hepatotoxic agents on polyribosomes and protein synthesis in the livers of rats fed purified diets containing hepatocarcinogens.
Topics: 2-Acetylaminofluorene; Acute Disease; Animals; Carbon Tetrachloride; Carcinogens; Chemical and Drug | 1982 |
["In vitro" stimulation of TBArs. Production by carbon tetrachloride in MH1C1 hepatoma (author's transl)].
Topics: Animals; Carbon Tetrachloride; Chemical Phenomena; Chemistry; Lipid Peroxides; Liver Neoplasms, Expe | 1981 |
Biochemical alterations in hepatic tissue of ethionine and N-nitrosodimethylamine treated mice, and in a transplantable tumor of rat.
Topics: Animals; Bromobenzenes; Carbon Tetrachloride; Dimethylnitrosamine; DNA; Ethionine; Female; Liver; Li | 1980 |
Identification of clastogenic and/or aneugenic events during the preneoplastic stages of experimental rat hepatocarcinogenesis by fluorescence in situ hybridization.
Topics: Aneuploidy; Animals; Carbon Tetrachloride; Chromosome Aberrations; Diethylnitrosamine; In Situ Hybri | 1995 |
Cross-linked cytokeratin polypeptides in liver and hepatoma cells: possible association with the process of cell degeneration and death.
Topics: Animals; Carbon Tetrachloride; Cell Survival; Ischemia; Keratins; Liver; Liver Circulation; Liver Ne | 1993 |
Hepatic tumors induced by carbon tetrachloride in transgenic mice carrying a human c-H-ras proto-oncogene without mutations.
Topics: Animals; Base Sequence; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Death; DNA, Neoplasm; | 1994 |
Simultaneous induction of liver cirrhosis and hepatocellular carcinomas in F-344 rats: establishment of a short hepatocarcinogenesis model.
Topics: Animals; Carbon Tetrachloride; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Hepatectomy; | 1994 |
Decreased hepatocarcinogenic effect of diethylnitrosamine in experimentally induced liver cirrhosis in rat: delay or inhibition?
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Diethylnitrosamine; Liver; Liver Cirr | 1994 |
Frequency and DNA content of micronuclei in rat parenchymal liver cells during experimental hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Cell Nucleus; Diethylnitrosamine; DNA; Liver; | 1993 |
Carbon tetrachloride promoted malondialdehyde formation in liver microsomal and nuclear preparations from Sprague Dawley or Osborne Mendel male rats.
Topics: Animals; Carbon Tetrachloride; Cell Nucleus; Disease Susceptibility; Lipid Peroxidation; Liver; Live | 1993 |
Effects of carbon tetrachloride, ethanol and acetaldehyde on diethylnitrosamine-induced hepatocarcinogenesis in rats.
Topics: Acetaldehyde; Animals; Animals, Newborn; Body Weight; Carbon Tetrachloride; Diethylnitrosamine; Etha | 1993 |
High expression of cytochrome P450 2a-5 (coumarin 7-hydroxylase) in mouse hepatomas.
Topics: Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Carbon Tetrach | 1993 |
Sex hormones and trace elements in rat CCL4-induced cirrhosis and hepatocellular carcinoma.
Topics: Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; Copper; | 1993 |
Demonstration of extensive chromatin cleavage in transplanted Morris hepatoma 7777 tissue: apoptosis or necrosis?
Topics: Animals; Apoptosis; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Death; Chromatin; DNA; Isc | 1993 |
Hepatocarcinogenic potency of mixed and pure enantiomers of trans-7,8-dihydrobenzo[a]pyrene-7,8-diol in trout.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carbon Tetrachloride; Dihydroxydihydrobenzopyrenes; Dis | 1993 |
Effects of cell proliferation and cell death (apoptosis and necrosis) on the early stages of rat hepatocarcinogenesis.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Carcinogens; Cell Death; Cell Division; Diethylnitrosamine | 1996 |
Effect of cell proliferation on initiation of aflatoxin B1-induced enzyme altered hepatic foci in rats and hamsters.
Topics: Aflatoxin B1; Animals; Carbon Tetrachloride; Carcinogens; Cell Division; Cricetinae; Cytochrome P-45 | 1996 |
Role of H-ras gene in chronic liver damage in mice. By using transgenic mice carrying a human C-H-ras proto-oncogene without mutations.
Topics: Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Gene Expression Regulation, Neoplastic; Ge | 1997 |
Levels of transforming growth factor beta and transforming growth factor beta receptors in rat liver during growth, regression by apoptosis and neoplasia.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Female; Hyperplasia; Liver; Liver Neoplasms, Experimental; | 1998 |
Enhancement of aflatoxin B1-induced enzyme altered hepatic foci in rats by treatment with carbon tetrachloride.
Topics: Aflatoxin B1; Animals; Carbon Tetrachloride; Drug Synergism; Fibrosis; gamma-Glutamyltransferase; Gl | 1998 |
Dietary iron overload inhibits carbon tetrachloride-induced promotion in chemical hepatocarcinogenesis: effects on cell proliferation, apoptosis, and antioxidation.
Topics: Animals; Antioxidants; Apoptosis; Body Weight; Carbon Tetrachloride; Carcinogens; Cell Division; Die | 1999 |
Development of resistance during the early stages of experimental liver carcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinogens; Diethylnitrosamine; Drug Resistan | 1999 |
Accumulation of extracellular matrix in the liver induces high metastatic potential of hepatocellular carcinoma to the lung.
Topics: Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; DNA Primers; Extracellular Matrix; Extrace | 2001 |
Cirrhosis and carcinoma of the liver in male rats given subcutaneous carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Carcinogens; Injections, Subcutaneous; Liver Cirrhosis; Liver Neoplas | 1970 |
Chemoprevention of aflatoxin B1-initiated and carbon tetrachloride-promoted hepatocarcinogenesis in the rat by green tea.
Topics: Aflatoxin B1; Animals; Carbon Tetrachloride; Cell Division; Cell Transformation, Neoplastic; Fibrosi | 2000 |
Role of oxidative DNA damage caused by carbon tetrachloride-induced liver injury -- enhancement of MeIQ-induced glutathione S-transferase placental form-positive foci in rats.
Topics: Animals; Bromodeoxyuridine; Carbon Tetrachloride; Carcinogens; DNA; DNA Damage; DNA Primers; DNA-For | 2002 |
Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Diab | 2002 |
Inhibition of 3H-demethylphalloin uptake in isolated rat hepatocytes under various experimental conditions.
Topics: Alkaloids; Animals; Carbon Tetrachloride; In Vitro Techniques; Liver; Liver Neoplasms, Experimental; | 1979 |
Low-molecular weight nucleic acids in the blood of rats with Zajdela's hepatoma.
Topics: Animals; Carbon Tetrachloride; DNA, Neoplasm; Immunosuppression Therapy; Liver; Liver Neoplasms, Exp | 1978 |
Mitogen-induced liver hyperplasia does not substitute for compensatory regeneration during promotion of chemical hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Cell Division; Diethylnitrosamine; gamma-Gluta | 1992 |
Modification of DENA-induced hepatocarcinogenesis by CCl4 cirrhosis. Comparison of the marker enzyme patterns.
Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Drug Administrati | 1992 |
Choline enhances acetylaminofluorene promotion of liver carcinogenesis in female but not in male rats.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Choline; Diethylnitrosamine; Drug Synergism; F | 1992 |
The cancer-initiating potential of the fumonisin B mycotoxins.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinogenicity Tests; Carcinogens, Environmen | 1992 |
Induction of preneoplastic lesions by a low dose of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in the livers of rats treated with carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; DNA; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Pr | 1992 |
Enhancement of hepatocarcinogenesis in rainbow trout with carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Carcinogenicity Tests; Cell Division; Cocarcinogenesis; Liver; Liver | 1991 |
Different effects of carbon tetrachloride on carcinogen-induced hepatocellular carcinoma and normal liver of the rat: lowered lipid peroxidation and accelerated necrosis in cancer.
Topics: Animals; Ascorbic Acid; Azo Compounds; Carbon Tetrachloride; Fatty Acids; Fatty Liver; Lipid Peroxid | 1991 |
Relationship of hepatocarcinogenicity and hepatocellular proliferation induced by mutagenic noncarcinogens vs carcinogens. II. 1- vs 2-nitropropane.
Topics: Alanine Transaminase; Animals; Body Weight; Bromodeoxyuridine; Carbon Tetrachloride; Carcinogens; Ce | 1991 |
Inhibitory and promoting effects of carbon tetrachloride-induced liver cirrhosis on the diethylnitrosamine hepatocarcinogenesis in rats.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Diethylnitrosamine; Liver; Liver Cirr | 1991 |
Peroxisome proliferation and modulation of rat liver carcinogenesis by 2,4-dichlorophenoxyacetic acid, 2,4,5-trichlorophenoxyacetic acid, perfluorooctanoic acid and nafenopin.
Topics: 2-Acetylaminofluorene; 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; C | 1990 |
Cell lineages in liver carcinogenesis: possible clues from studies of the distribution of alpha-fetoprotein RNA sequences in cell populations isolated from normal, regenerating, and preneoplastic rat livers.
Topics: alpha-Fetoproteins; Animals; Base Sequence; Carbon Tetrachloride; Liver; Liver Neoplasms, Experiment | 1985 |
Cell population kinetics and ploidy rate of early focal lesions during hepatocarcinogenesis in the rat.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Cell Count; Diethylnitrosamine; DNA; Liver; Li | 1989 |
Biochemical and morphologic studies of heterogeneous lobe responses in hepatocarcinogenesis.
Topics: Alkylation; Animals; Carbon Radioisotopes; Carbon Tetrachloride; Cell Division; Diethylnitrosamine; | 1986 |
Anti-carcinogenic effects of a serine protease inhibitor (FOY-305) through the suppression of neutral serine protease activity during chemical hepatocarcinogenesis in rats.
Topics: Animals; Antineoplastic Agents; Carbon Tetrachloride; Endopeptidases; Esters; Gabexate; gamma-Glutam | 1987 |
Liver cell proliferation induced by the mitogen ethylene dibromide, unlike compensatory cell proliferation, does not achieve initiation of rat liver carcinogenesis by diethylnitrosamine.
Topics: Animals; Carbon Tetrachloride; Cell Division; Diethylnitrosamine; Ethylene Dibromide; gamma-Glutamyl | 1987 |
Induction and promotion of gamma-glutamyltranspeptidase-positive foci in the rat liver by methylglyoxal.
Topics: 2-Acetylaminofluorene; Aldehydes; Animals; Carbon Tetrachloride; gamma-Glutamyltransferase; Liver Ne | 1988 |
Distribution pattern of liver matrix proteins, fibronectin and type I collagen, in DAB-induced hepatoma of rat.
Topics: Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Collagen; Female; Fibronectins; Histocytoc | 1985 |
Diethyl-nitrosamine hepatocarcinogenesis in cirrhotic rats.
Topics: Animals; Carbon Tetrachloride; Diethylnitrosamine; Liver Cirrhosis, Experimental; Liver Neoplasms, E | 1987 |
Enhancement of dimethylnitrosamine-initiated hepatocarcinogenesis in hamsters by subsequent administration of carbon tetrachloride but not phenobarbital or p,p'-dichlorodiphenyltrichloroethane.
Topics: Animals; Carbon Tetrachloride; Cocarcinogenesis; Cricetinae; DDT; Dimethylnitrosamine; Liver Neoplas | 1987 |
Compared promoting potential of D-galactosamine, carbon tetrachloride and partial hepatectomy in rapid induction of preneoplastic liver lesions in the rat.
Topics: Animals; Body Weight; Carbon Tetrachloride; Cell Division; Cocarcinogenesis; Galactosamine; Glutathi | 1987 |
Enhancing effects of carbon tetrachloride in mouse hepatocarcinogenesis.
Topics: Animals; Carbon Tetrachloride; Cocarcinogenesis; Diethylnitrosamine; Female; Liver; Liver Neoplasms, | 1986 |
Enhanced O6-methylguanine-DNA alkyltransferase activity in rat liver nodules.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; DNA Repair; Female; Kinetics; Liver; Liver Neo | 1986 |
Influence of the duration and the delay of administration of phenobarbital on its modulating effect on rat hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinogens; Drug Administration Schedule; Liv | 1987 |
Failure of mitogen-induced cell proliferation to achieve initiation of rat liver carcinogenesis.
Topics: Animals; Carbon Tetrachloride; Cell Division; Diethylnitrosamine; Hepatectomy; Lead; Liver Neoplasms | 1987 |
Effects of liver damage induced by polychlorinated biphenyls (PCB) on cadmium metabolism in mice.
Topics: Animals; Cadmium; Carbon Tetrachloride; Kidney; Liver; Liver Neoplasms, Experimental; Male; Mice; Mi | 1985 |
Endogenous hepatic growth-modulating factors and effects of a choline-devoid diet and of phenobarbital on hepatocarcinogenesis in the rat.
Topics: Animals; Carbon Tetrachloride; Choline; Diet; DNA; Ethionine; Growth Substances; Liver; Liver Neopla | 1985 |