carbon tetrachloride has been researched along with Diabetes Mellitus, Type 2 in 3 studies
Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have developed a type 2 diabetes rat model that closely resembles the diabetic patients and takes only 24 days to develop robust diabetes." | 1.32 | Potentiation of carbon tetrachloride hepatotoxicity and lethality in type 2 diabetic rats. ( Dnyanmote, AV; Latendresse, JR; Limaye, PB; Mehendale, HM; Sawant, SP; Shankar, K, 2004) |
| " We studied the effects of TRZ on the hepatotoxicity of carbon tetrachloride (CCl(4)) and acetaminophen (APAP) in rats, both of which exert their toxic effects through bioactivation associated with cytochrome P450 3A (CYP3A) and 2E1 (CYP2E1)." | 1.31 | Troglitazone enhances the hepatotoxicity of acetaminophen by inducing CYP3A in rats. ( Kaneko, T; Li, J; Qin, LQ; Sato, A; Wang, PY; Wang, Y, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sawant, SP | 1 |
| Dnyanmote, AV | 1 |
| Shankar, K | 1 |
| Limaye, PB | 1 |
| Latendresse, JR | 1 |
| Mehendale, HM | 1 |
| Ishikawa, T | 1 |
| Mori, M | 1 |
| Ichikawa, Y | 1 |
| Kitoh, J | 1 |
| Yamashita, K | 1 |
| Li, J | 1 |
| Kaneko, T | 1 |
| Wang, Y | 1 |
| Qin, LQ | 1 |
| Wang, PY | 1 |
| Sato, A | 1 |
3 other studies available for carbon tetrachloride and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Potentiation of carbon tetrachloride hepatotoxicity and lethality in type 2 diabetic rats.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur | 2004 |
Three-dimensional observations of spatial arrangement of hepatic zonation and vein system in mice and house musk shrews.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Diabetes Mellitus, Type 2; Di | 2000 |
Troglitazone enhances the hepatotoxicity of acetaminophen by inducing CYP3A in rats.
Topics: Acetaminophen; Administration, Oral; Animals; Aryl Hydrocarbon Hydroxylases; Carbon Tetrachloride; C | 2002 |