Page last updated: 2024-11-08

carbon tetrachloride and Cruveilhier-Baumgarten Syndrome

carbon tetrachloride has been researched along with Cruveilhier-Baumgarten Syndrome in 89 studies

Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.

Cruveilhier-Baumgarten Syndrome: Liver cirrhosis with intrahepatic portal obstruction, HYPERTENSION, and patent UMBILICAL VEINS.

Research Excerpts

ExcerptRelevanceReference
" NaHS protected liver function, attenuated liver fibrosis, inhibited inflammation, and reduced the portal pressure, evidenced by the alterations of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), hyaluronic acid (HA), albumin, tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6 and soluble intercellular adhesion molecule (ICAM)-1, liver histology, hepatic hydroxyproline content and α-smooth muscle actin (SMA) expression."7.77Hydrogen sulfide attenuates carbon tetrachloride-induced hepatotoxicity, liver cirrhosis and portal hypertension in rats. ( Dong, X; Jiang, H; Jiang, X; Kang, K; Kanwar, JR; Li, J; Pan, S; Qiao, H; Sun, X; Tan, G; Zhao, M, 2011)
" This study was conducted to investigate any protective effect of early propranolol administration in the development and degree of esophageal varices in cirrhotic rats with portal hypertension."7.75Early propranolol administration does not prevent development of esophageal varices in cirrhotic rats. ( Alatsakis, M; Ballas, KD; Marakis, GN; Pavlidis, TE; Psarras, K; Rafailidis, S; Sakantamis, AK; Tzioufa-Asimakopoulou, V, 2009)
"In conclusion, carvedilol may alleviate liver cirrhosis in rats by inhibiting HSC activation, proliferation, invasion and collagen synthesis."5.51Carvedilol improves liver cirrhosis in rats by inhibiting hepatic stellate cell activation, proliferation, invasion and collagen synthesis. ( Li, G; Li, Z; Ling, L; Meng, D; Wang, G; Zhang, C, 2019)
"Portal hypertension is triggered by vasodilation due to impaired contraction of extrahepatic vessels."5.35Vascular hyporesponsiveness to angiotensin II in rats with CCl(4)-induced liver cirrhosis. ( Heller, J; Hennenberg, M; Kohistani, AZ; Sauerbruch, T; Trebicka, J, 2009)
" In carbon tetrachloride-induced micronodular cirrhosis, portal sinusoidal flow, which reaches liver parenchyma, is high, and this is more pronounced in the presence of ascites."4.81Characterisation of portal hypertension models by microspheres in anaesthetised rats: a comparison of liver flow. ( Reichen, J; Sägesser, H; Van de Casteele, M; Zimmermann, H, 2001)
"The effect of systemic treatment with adipose tissue-derived MSCs, pre-differentiated into hepatocytic cells, was investigated in a rat model of liver cirrhosis induced by chronic inhalation of carbon tetrachloride."3.85Improvement of portal venous pressure in cirrhotic rat livers by systemic treatment with adipose tissue-derived mesenchymal stromal cells. ( Brückner, S; Christ, B; Hempel, M; Roderfeld, M; Roeb, E; Schwill, F; Thonig, A; Zipprich, A, 2017)
"Droxidopa might be an effective therapeutic agent for hemodynamic and renal alterations of liver cirrhosis and should be tested in cirrhosis patients."3.78Droxidopa, an oral norepinephrine precursor, improves hemodynamic and renal alterations of portal hypertensive rats. ( Augustin, S; Brull, A; Coll, M; Esteban, R; Ezkurdia, N; Genescà, J; Guardia, J; Martell, M; Raurell, I; Rodriguez, S, 2012)
" NaHS protected liver function, attenuated liver fibrosis, inhibited inflammation, and reduced the portal pressure, evidenced by the alterations of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), hyaluronic acid (HA), albumin, tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6 and soluble intercellular adhesion molecule (ICAM)-1, liver histology, hepatic hydroxyproline content and α-smooth muscle actin (SMA) expression."3.77Hydrogen sulfide attenuates carbon tetrachloride-induced hepatotoxicity, liver cirrhosis and portal hypertension in rats. ( Dong, X; Jiang, H; Jiang, X; Kang, K; Kanwar, JR; Li, J; Pan, S; Qiao, H; Sun, X; Tan, G; Zhao, M, 2011)
" This study was conducted to investigate any protective effect of early propranolol administration in the development and degree of esophageal varices in cirrhotic rats with portal hypertension."3.75Early propranolol administration does not prevent development of esophageal varices in cirrhotic rats. ( Alatsakis, M; Ballas, KD; Marakis, GN; Pavlidis, TE; Psarras, K; Rafailidis, S; Sakantamis, AK; Tzioufa-Asimakopoulou, V, 2009)
"In an effort to develop a reproducible model of liver cirrhosis and esophageal varices, we administered phenobarbital (PhB) and carbon tetrachloride (CCl4) in 32 rats that had previously undergone complete devascularization of the left renal vein (DLRV)."3.71A rat model of liver cirrhosis and esophageal varices. ( Alatsakis, MB; Ballas, KD; Sakadamis, AK; Tzioufa-Asimakopoulou, V, 2001)
"The present study investigated whether, in rats with portal hypertension due to cirrhosis of the liver induced by carbon tetrachloride, blood volume restitution following a hemorrhage produces an increase of portal pressure beyond control values, as observed in rats with prehepatic portal hypertension."3.67Hemodynamic effects of blood volume restitution following a hemorrhage in rats with portal hypertension due to cirrhosis of the liver: influence of the extent of portal-systemic shunting. ( Arderiu, M; Bosch, J; Kravetz, D; Pilar Pizcueta, M; Rodés, J, 1989)
"Portal hypertension is a severe complication caused by various chronic liver diseases."1.56Assessment of a biofluid mechanics-based model for calculating portal pressure in canines. ( Deng, WS; Lin, JY; Luo, M; Song, CL; Sun, LC; Wu, LZ; Zhang, CH; Zheng, L; Zhu, YM, 2020)
"In conclusion, carvedilol may alleviate liver cirrhosis in rats by inhibiting HSC activation, proliferation, invasion and collagen synthesis."1.51Carvedilol improves liver cirrhosis in rats by inhibiting hepatic stellate cell activation, proliferation, invasion and collagen synthesis. ( Li, G; Li, Z; Ling, L; Meng, D; Wang, G; Zhang, C, 2019)
"Portal hypertension is a frequent pathological symptom occurring especially in hepatic fibrosis and cirrhosis."1.46Dihydroartemisinin counteracts fibrotic portal hypertension via farnesoid X receptor-dependent inhibition of hepatic stellate cell contraction. ( Lu, C; Shao, J; Xu, W; Yao, S; Zhang, F; Zheng, S, 2017)
" The underlying mechanisms may relate to rescue NO bioavailability from macrophage-derived peroxynitrite in portal triads."1.39Glycyrrhizinate reduces portal hypertension in isolated perfused rat livers with chronic hepatitis. ( Cai, DY; Deng, B; Liu, XT; Song, YJ; Wang, YQ; Xu, XY; Yang, SJ; Zhang, T; Zhao, X, 2013)
"We also evaluated liver fibrosis by Sirius Red staining of liver sections, collagen-1, NFκB, TGFβ mRNA expression, and desmin and α-smooth muscle actin (α-SMA) protein expression, as a surrogate of hepatic stellate cell activation."1.39Resveratrol improves intrahepatic endothelial dysfunction and reduces hepatic fibrosis and portal pressure in cirrhotic rats. ( Bosch, J; Di Pascoli, M; Diví, M; García-Pagán, JC; Gracia-Sancho, J; Rodríguez-Vilarrupla, A; Rosado, E; Vilaseca, M, 2013)
" Nitric oxide (NO) bioavailability and eNOS activation were measured in hepatic endothelial cells (HEC) isolated from cirrhotic rat livers."1.38PPARα activation improves endothelial dysfunction and reduces fibrosis and portal pressure in cirrhotic rats. ( Bosch, J; García-Calderó, H; García-Pagán, JC; Laviña, B; Rodríguez-Vilarrupla, A; Roglans, N; Rosado, E; Russo, L, 2012)
"Liver cirrhosis is associated with bacterial translocation (BT) and endotoxemia."1.38Intestinal bacterial translocation in rats with cirrhosis is related to compromised Paneth cell antimicrobial host defense. ( Beisner, J; Bevins, CL; Hofmann, C; Nuding, S; Schoelmerich, J; Stange, EF; Teltschik, Z; Wehkamp, J; Wiest, R, 2012)
"Cirrhotic portal hypertension is characterized by mesenteric arterial vasodilation and hyporeactivity to vasoconstrictors."1.37Increased myoendothelial gap junctions mediate the enhanced response to epoxyeicosatrienoic acid and acetylcholine in mesenteric arterial vessels of cirrhotic rats. ( Angeli, P; Bolognesi, M; Calabrese, F; Di Pascoli, M; Gatta, A; Lunardi, F; Merkel, C; Pontisso, P; Sacerdoti, D; Turato, C; Verardo, A; Zampieri, F, 2011)
"These models represent, respectively, a secondary biliary cirrhosis and alcoholic cirrhosis."1.35Comparison of three research models of portal hypertension in mice: macroscopic, histological and portal pressure evaluation. ( Colle, I; De Vos, M; Geerts, AM; Praet, M; Van Vlierberghe, H; Vanheule, E, 2008)
" NO scavenging by superoxide (O(2)(-)) further contributes to a reduction of NO bioavailability in cirrhotic livers."1.35Superoxide dismutase gene transfer reduces portal pressure in CCl4 cirrhotic rats with portal hypertension. ( Bosch, J; Chu, Y; García-Pagán, JC; Gracia-Sancho, J; Heistad, DD; Laviña, B; Rodríguez-Vilarrupla, A, 2009)
"Portal hypertension is triggered by vasodilation due to impaired contraction of extrahepatic vessels."1.35Vascular hyporesponsiveness to angiotensin II in rats with CCl(4)-induced liver cirrhosis. ( Heller, J; Hennenberg, M; Kohistani, AZ; Sauerbruch, T; Trebicka, J, 2009)
"Portal hypertension is a hemodynamic syndrome due to pathological increase in portal flow and portal pressure."1.35Combined use of propranolol and nifedipine offers better effects on portal vein nonuniform remodeling in carbon tetrachloride (CCl(4))-induced portal hypertensive rats. ( Jiang, ZL; Qin, KR; Shi, B; Wu, GQ; Zhang, ZQ; Zhu, L, 2009)
"A model of liver cirrhosis was replicated in rats by intra-peritoneal injection of CCl4 for 8 wk."1.33Effect of increased hepatic platelet activating factor and its receptor portal hypertension in CCl4-induced liver cirrhosis. ( Feng, YY; Han, J; Lu, YY; Ma, XM; Su, SH; Wang, CP; Xiang, Y; Yang, YP, 2006)
"Hepatic cirrhosis was induced in male Sprague-Dawley rats by intraperitoneal injection of carbon tetrachloride, and the cirrhotic rats were divided into three groups:Liposome-pcDNA(3)/iNOS (n = 10), Tris buffer (n = 10) and nude plasmid (n = 10), which were injected into the portal vein of experiment cirrhotic rats respectively."1.32[Experimental study on iNOS gene transfer mediated by liposome to treat portal hypertension in cirrhotic rats]. ( Luo, HF; Qiu, JF; Wu, ZY; Zhang, ZQ, 2004)
"Portal hypertension was successfully induced in 15 dogs."1.32[Morphology of portal hypertension at the early stage of liver damage induced by CCl4: an experimental study with dogs]. ( Wei, YW; Xue, DB; Zhang, RP; Zhang, WH, 2004)
"To assess the effects of the early and chronic administration of losartan--a specific angiotensin II receptor antagonist--in the prevention of hepatic fibrosis and portal hypertension."1.31Hemodynamic and antifibrotic effects of losartan in rats with liver fibrosis and/or portal hypertension. ( Calès, P; Chappard, D; Croquet, V; Douay, O; Gallois, Y; Moal, F; Oberti, F; Roux, J; Veal, N; Vuillemin, E; Wang, J, 2002)
"Liver cirrhosis was induced by an intraperitoneal injection of 50% CCl(4) (0."1.31[Effects of ET-1 on isolated perfused rat liver and vascular rings at two stages of cirrhosis]. ( Fang, H; Feng, Z; Gao, J; Yang, C; Yao, D; Yao, X, 2002)
" Chronic administration of CCl(4) (10 weeks) induced a cirrhotic state, characterized by increased liver fibronectin and collagen types I and III content, enhanced expression of alpha-1 (I) collagen mRNA, portal hypertension, and liver dysfunction."1.31Adenosine reverses a preestablished CCl4-induced micronodular cirrhosis through enhancing collagenolytic activity and stimulating hepatocyte cell proliferation in rats. ( De Sánchez, VC; Díaz-Muñoz, M; Hernández-Muñoz, R; López, V; Sánchez-Sevilla, L; Suárez-Cuenca, JA; Trejo-Solís, C; Yáñez, L, 2001)
" This study investigated the effects of chronic administration of octreotide on systemic and portal haemodynamics and the development of portal hypertensive gastropathy in carbon tetrachloride-induced cirrhotic rats."1.30Chronic administration of octreotide ameliorates portal hypertension and portal hypertensive gastropathy in rats with cirrhosis. ( Chan, CC; Chang, FY; Chu, CJ; Lee, FY; Lee, SD; Lin, HC; Lin, HJ; Tai, CC; Wang, SS; Wu, SL, 1998)
"Since portal hypertension affects the gastric mucosa, leading to congestive gastropathy and thus to increased incidence of bleeding, it is one of the possible causes of increased permeability of gastric mucosal capillaries."1.29Increased capillary endothelial leakage in portal hypertensive gastric mucosa: fluorescence microscopy in CCl4-induced cirrhotic rats. ( Aletras, H; Eleftheriadis, E; Karkavelas, G; Kotzampassi, K; Papadimitriou, C, 1995)
" This increase was abolished by chronic administration of N(omega)-nitro-L-arginine methyl ester."1.29Comparison of vascular nitric oxide production and systemic hemodynamics in cirrhosis versus prehepatic portal hypertension in rats. ( Ginés, P; Martin, PY; McMurtry, I; Morris, K; Niederberger, M; Schrier, RW; Tsai, P, 1996)
" On the other hand, the initial decrease in portal pressure was augmented in rats with partial portal vein ligation, and disappeared at higher dosage in CCl4-treated rats."1.28Effects of endothelin in portal hypertensive rats. ( Kuo, JS; Lin, HC; Yang, MC; Yu, PC, 1992)

Research

Studies (89)

TimeframeStudies, this research(%)All Research%
pre-19907 (7.87)18.7374
1990's17 (19.10)18.2507
2000's31 (34.83)29.6817
2010's30 (33.71)24.3611
2020's4 (4.49)2.80

Authors

AuthorsStudies
Lafoz, E1
Campreciós, G1
García-Calderó, H3
Anton, A1
Vilaseca, M2
Ruart, M1
Guasch, E1
Garrabou, G1
Delgado, TC1
Martínez-Chantar, ML1
García-Martínez, R1
Gracia-Sancho, J4
Hernández-Gea, V1
García-Pagán, JC6
Rampa, DR2
Feng, H2
Allur-Subramaniyan, S2
Shim, K2
Pekcec, A2
Lee, D2
Doods, H2
Wu, D2
Zhang, B2
Ji, LH1
Zhang, CG2
Zhao, G2
Wu, ZY3
Lin, JY2
Zhang, CH2
Zheng, L3
Song, CL1
Deng, WS3
Zhu, YM2
Wu, LZ1
Sun, LC1
Luo, M3
Chen, J1
Argemi, J1
Odena, G1
Xu, MJ1
Cai, Y1
Massey, V1
Parrish, A1
Vadigepalli, R1
Altamirano, J1
Cabezas, J1
Gines, P2
Caballeria, J1
Snider, N1
Sancho-Bru, P1
Akira, S1
Rusyn, I1
Gao, B1
Bataller, R1
Klein, S2
Schierwagen, R2
Uschner, FE2
Trebicka, J3
Gui, L1
Brückner, S1
Zipprich, A1
Hempel, M1
Thonig, A1
Schwill, F1
Roderfeld, M1
Roeb, E1
Christ, B1
Ling, L1
Li, G1
Wang, G1
Meng, D1
Li, Z2
Zhang, C1
Fallowfield, JA1
Hayden, AL1
Snowdon, VK1
Aucott, RL1
Stutchfield, BM1
Mole, DJ1
Pellicoro, A1
Gordon-Walker, TT1
Henke, A1
Schrader, J1
Trivedi, PJ1
Princivalle, M1
Forbes, SJ1
Collins, JE1
Iredale, JP1
Zhao, X1
Deng, B1
Xu, XY1
Yang, SJ1
Zhang, T1
Song, YJ1
Liu, XT1
Wang, YQ1
Cai, DY1
Deng, G2
Huang, XJ1
Luo, HW1
Huang, FZ2
Liu, XY2
Wang, YH1
Li, B2
Shao, Q2
Ji, D2
Li, F2
Chen, G2
Zhai, L1
Qiu, LY1
Zu, Y1
Yan, Y1
Ren, XZ1
Zhao, JF1
Liu, YJ1
Liu, JB1
Qian, LX1
Zhao, TY1
Su, LP1
Ma, CY1
Zhai, XH1
Duan, ZJ1
Zhu, Y1
Li, CY1
Wang, LX1
Yang, D1
Rick, J1
Lehmann, J1
Schierwagen, IG1
Verbeke, L1
Hittatiya, K1
Manekeller, S1
Strassburg, CP1
Wagner, KU1
Sayeski, PP1
Wolf, D1
Laleman, W1
Sauerbruch, T2
Duan, M2
Chen, W1
Xu, W1
Lu, C1
Zhang, F1
Shao, J1
Yao, S1
Zheng, S1
Qin, J1
He, Y1
Matei, V1
Rodríguez-Vilarrupla, A6
Deulofeu, R1
Fernández, M2
Bosch, J8
Geerts, AM1
Vanheule, E1
Praet, M1
Van Vlierberghe, H2
De Vos, M1
Colle, I2
Laviña, B2
Chu, Y1
Heistad, DD1
Alatsakis, M1
Ballas, KD2
Pavlidis, TE1
Psarras, K1
Rafailidis, S1
Tzioufa-Asimakopoulou, V2
Marakis, GN1
Sakantamis, AK1
Zhang, ZQ2
Shi, B1
Wu, GQ1
Qin, KR1
Jiang, ZL1
Zhu, L1
Renga, B1
Mencarelli, A2
Migliorati, M1
Distrutti, E1
Fiorucci, S2
Hong, JJ1
Pan, FY1
Qian, Y1
Cheng, LC1
Zhang, HX1
Xue, B1
Li, CJ1
Hennenberg, M1
Kohistani, AZ1
Heller, J1
Theodorakis, NG1
Wang, YN1
Wu, JM1
Maluccio, MA1
Sitzmann, JV2
Skill, NJ1
Resch, M1
Wiest, R3
Moleda, L2
Fredersdorf, S1
Stoelcker, B1
Schroeder, JA1
Schölmerich, J1
Endemann, DH1
Domenicali, M1
Caraceni, P1
Giannone, F1
Baldassarre, M1
Lucchetti, G1
Quarta, C1
Patti, C1
Catani, L1
Nanni, C1
Lemoli, RM1
Bernardi, M1
Van Steenkiste, C1
Trachet, B1
Casteleyn, C1
van Loo, D1
Van Hoorebeke, L1
Segers, P1
Geerts, A1
Bolognesi, M2
Zampieri, F1
Di Pascoli, M2
Verardo, A1
Turato, C1
Calabrese, F1
Lunardi, F1
Pontisso, P1
Angeli, P1
Merkel, C1
Gatta, A2
Sacerdoti, D2
Jiang, H2
Gaiani, S1
McGiff, JC1
Tan, G1
Pan, S1
Li, J1
Dong, X1
Kang, K1
Zhao, M1
Jiang, X1
Kanwar, JR1
Qiao, H1
Sun, X1
Teltschik, Z1
Beisner, J1
Nuding, S1
Hofmann, C1
Schoelmerich, J1
Bevins, CL1
Stange, EF1
Wehkamp, J1
He, XJ1
Huang, TZ1
Wang, PJ1
Peng, XC1
Li, WC1
Wang, J2
Tang, J1
Feng, N1
Yu, MH1
Russo, L1
Rosado, E3
Roglans, N1
Coll, M2
Rodriguez, S1
Raurell, I2
Ezkurdia, N1
Brull, A1
Augustin, S1
Guardia, J3
Esteban, R3
Martell, M2
Genescà, J2
Sakamoto, M1
Nakamura, T1
Torimura, T1
Iwamoto, H1
Masuda, H1
Koga, H1
Abe, M1
Hashimoto, O1
Ueno, T1
Sata, M1
Guillaume, M1
Mancini, A1
Dietrich, P1
Kees, F1
Müller, M1
Straub, RH1
Hellerbrand, C1
Liu, CH1
Huang, XT1
Li, YY1
Zheng, X1
Li, N1
Mi, SQ1
Wang, NS1
Diví, M1
Reboredo, M1
Chang, HC1
Barbero, R1
Rodríguez-Ortigosa, CM1
Pérez-Vizcaíno, F1
Morán, A1
García, M1
Banales, JM1
Carreño, N1
Alegre, F1
Herrero, I1
Quiroga, J1
Prieto, J1
Sangro, B1
Croquet, V1
Moal, F2
Veal, N2
Oberti, F2
Roux, J1
Vuillemin, E2
Gallois, Y1
Douay, O1
Chappard, D1
Calès, P2
Chiva, M1
Guarner, C1
Peralta, C1
Llovet, T1
Gómez, G1
Soriano, G1
Balanzó, J1
Yao, D1
Yao, X1
Yang, C1
Feng, Z1
Fang, H1
Gao, J1
van der Merwe, SW1
van den Bogaerde, JB1
Goosen, C1
Maree, FF1
Milner, RJ1
Schnitzler, CM1
Biscardi, A1
Mesquita, JM1
Engelbrecht, G1
Kahn, D1
Fevery, J1
Wang, H1
Chen, XP1
Qiu, FZ1
Qiu, JF1
Luo, HF1
Thirunavukkarasu, C1
Yang, Y1
Subbotin, VM2
Harvey, SA1
Fung, J1
Gandhi, CR2
Zhang, RP1
Zhang, WH1
Xue, DB1
Wei, YW1
Sansoè, G1
Aragno, M1
Mastrocola, R1
Restivo, F1
Mengozzi, G1
Smedile, A1
Rosina, F1
Danni, O1
Parola, M1
Rizzetto, M1
Wang, CP2
Han, J2
Ma, XM2
Dong, K1
Xiang, Y2
Su, SH2
Feng, YY2
Yang, YP2
Yao, GX1
Shen, ZY1
Xue, XB1
Yang, Z1
Lu, YY1
Luo, CQ1
Mejías, M1
Otero, T1
Oria, M1
Burns, RC1
Wu, Y1
Gomis, R1
Fernández-Alvarez, J1
Pizcueta, P1
Casamitjana, R1
Rodés, J2
Kotzampassi, K2
Karkavelas, G1
Eleftheriadis, E2
Papadimitriou, C1
Aletras, H1
Zhang, Y1
Qi, G1
Lui, J1
Niederberger, M1
Martin, PY1
Tsai, P1
Morris, K1
McMurtry, I1
Schrier, RW1
Bozkurt, S1
Ersoy, E1
Tekýn, HE1
Bayram, O1
Anadol, Z1
Onuk, E1
Ercan, ZS1
López-Talavera, JC1
Levitzki, A1
Martínez, M1
Gazit, A1
Rockey, DC1
Chung, JJ1
Nemoto, EM1
Watkins, SC1
Chan, CC1
Lee, FY1
Wang, SS1
Chang, FY1
Lin, HC2
Lin, HJ1
Chu, CJ1
Wu, SL1
Tai, CC1
Lee, SD1
Petrowsky, H1
Schmandra, T1
Lorey, T1
Hanisch, E1
Herrmann, G1
Fort, J1
Kaassis, M1
Pilette, C1
Loureiro-Silva, MR1
Molina, HM1
Borges, DR1
Sakadamis, AK1
Alatsakis, MB1
Antonelli, E1
Morelli, O1
Casini, A1
Mello, T1
Palazzetti, B1
Tallet, D1
del Soldato, P1
Morelli, A1
Van de Casteele, M1
Sägesser, H1
Zimmermann, H1
Reichen, J1
Hernández-Muñoz, R1
Díaz-Muñoz, M1
Suárez-Cuenca, JA1
Trejo-Solís, C1
López, V1
Sánchez-Sevilla, L1
Yáñez, L1
De Sánchez, VC1
Wu, Z1
Zhou, J1
Chen, Z1
Zhou, H1
Jiao, Z1
Kuang, Y1
Yuan, J1
Wang, Q1
Zeng, M1
Yu, PC1
Kuo, JS1
Yang, MC1
Chen, S1
Blendis, LM1
Dagenais, M1
Giroux, L1
Belgiorno, J1
Huet, PM1
Miura, S1
Serizawa, H1
Hamada, Y1
Tanaka, S1
Yoshioka, M1
Hibi, T1
Tsuchiya, M1
Kravetz, D1
Arderiu, M1
Pilar Pizcueta, M1
Baddeley, RM2
Ejr, SJ1
Evans, J1
McLean, EK2
McLean, AE1
Sutton, PM1
Banerjee, AK1
Aikat, BK1
Hill, KR1
Fejfar, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Serelaxin To Lower Portal Pressure in Patients With Cirrhosis and Portal Hypertension[NCT02669875]Phase 215 participants (Actual)Interventional2017-10-18Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for carbon tetrachloride and Cruveilhier-Baumgarten Syndrome

ArticleYear
Characterisation of portal hypertension models by microspheres in anaesthetised rats: a comparison of liver flow.
    Pharmacology & therapeutics, 2001, Volume: 90, Issue:1

    Topics: Animals; Ascites; Bile Ducts; Blood Flow Velocity; Carbon Tetrachloride; Disease Models, Animal; Hem

2001
Hepatocyte swelling and portal hypertension.
    Journal of hepatology, 1992, Volume: 15, Issue:1-2

    Topics: Animals; Carbon Tetrachloride; Disease Models, Animal; Hepatomegaly; Hypertension, Portal; Liver; Li

1992

Other Studies

87 other studies available for carbon tetrachloride and Cruveilhier-Baumgarten Syndrome

ArticleYear
Impact of lifestyle interventions targeting physical exercise and caloric intake on cirrhosis regression in rats.
    American journal of physiology. Gastrointestinal and liver physiology, 2021, 12-01, Volume: 321, Issue:6

    Topics: Animals; Caloric Restriction; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Energy I

2021
Kinin B1 receptor blockade attenuates hepatic fibrosis and portal hypertension in chronic liver diseases in mice.
    Journal of translational medicine, 2022, 12-13, Volume: 20, Issue:1

    Topics: Animals; Carbon Tetrachloride; Fibrosis; Hepatic Stellate Cells; Humans; Hypertension, Portal; Kinin

2022
Kinin B1 receptor blockade attenuates hepatic fibrosis and portal hypertension in chronic liver diseases in mice.
    Journal of translational medicine, 2022, 12-13, Volume: 20, Issue:1

    Topics: Animals; Carbon Tetrachloride; Fibrosis; Hepatic Stellate Cells; Humans; Hypertension, Portal; Kinin

2022
Kinin B1 receptor blockade attenuates hepatic fibrosis and portal hypertension in chronic liver diseases in mice.
    Journal of translational medicine, 2022, 12-13, Volume: 20, Issue:1

    Topics: Animals; Carbon Tetrachloride; Fibrosis; Hepatic Stellate Cells; Humans; Hypertension, Portal; Kinin

2022
Kinin B1 receptor blockade attenuates hepatic fibrosis and portal hypertension in chronic liver diseases in mice.
    Journal of translational medicine, 2022, 12-13, Volume: 20, Issue:1

    Topics: Animals; Carbon Tetrachloride; Fibrosis; Hepatic Stellate Cells; Humans; Hypertension, Portal; Kinin

2022
Gender differences in vascular reactivity of mesenteric arterioles in portal hypertensive and non-portal hypertensive rats.
    World journal of gastroenterology, 2019, Oct-21, Volume: 25, Issue:39

    Topics: Animals; Arterioles; Carbon Tetrachloride; Female; Gonadal Steroid Hormones; Humans; Hypertension, P

2019
Assessment of a biofluid mechanics-based model for calculating portal pressure in canines.
    BMC veterinary research, 2020, Aug-26, Volume: 16, Issue:1

    Topics: Animals; Biomechanical Phenomena; Blood Flow Velocity; Carbon Tetrachloride; Dog Diseases; Dogs; Hyp

2020
Hepatic lipocalin 2 promotes liver fibrosis and portal hypertension.
    Scientific reports, 2020, 09-23, Volume: 10, Issue:1

    Topics: Animals; Carbon Tetrachloride; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Anim

2020
Mouse and Rat Models of Induction of Hepatic Fibrosis and Assessment of Portal Hypertension.
    Methods in molecular biology (Clifton, N.J.), 2017, Volume: 1627

    Topics: Animals; Carbon Tetrachloride; Disease Models, Animal; Hemodynamics; Hypertension, Portal; Liver Cir

2017
Soluble epoxide hydrolase inhibition with t-TUCB alleviates liver fibrosis and portal pressure in carbon tetrachloride-induced cirrhosis in rats.
    Clinics and research in hepatology and gastroenterology, 2018, Volume: 42, Issue:2

    Topics: Animals; Benzoates; Carbon Tetrachloride; Disease Models, Animal; Epoxide Hydrolases; Hypertension,

2018
Improvement of portal venous pressure in cirrhotic rat livers by systemic treatment with adipose tissue-derived mesenchymal stromal cells.
    Cytotherapy, 2017, Volume: 19, Issue:12

    Topics: Adipose Tissue; Animals; Carbon Tetrachloride; Cell Differentiation; Collagen; Disease Models, Anima

2017
Carvedilol improves liver cirrhosis in rats by inhibiting hepatic stellate cell activation, proliferation, invasion and collagen synthesis.
    Molecular medicine reports, 2019, Volume: 20, Issue:2

    Topics: Administration, Oral; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carb

2019
Relaxin modulates human and rat hepatic myofibroblast function and ameliorates portal hypertension in vivo.
    Hepatology (Baltimore, Md.), 2014, Volume: 59, Issue:4

    Topics: Actins; Animals; Carbon Tetrachloride; Cells, Cultured; Desmin; Disease Models, Animal; Glial Fibril

2014
Glycyrrhizinate reduces portal hypertension in isolated perfused rat livers with chronic hepatitis.
    World journal of gastroenterology, 2013, Sep-28, Volume: 19, Issue:36

    Topics: Animals; Antihypertensive Agents; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury, Chro

2013
Amelioration of carbon tetrachloride-induced cirrhosis and portal hypertension in rat using adenoviral gene transfer of Akt.
    World journal of gastroenterology, 2013, Volume: 19, Issue:43

    Topics: Adenoviridae; Animals; Apoptosis; Apoptosis Regulatory Proteins; Carbon Tetrachloride; Disease Model

2013
Mesenchymal stem cells mitigate cirrhosis through BMP7.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 35, Issue:2

    Topics: Animals; Bone Morphogenetic Protein 7; Carbon Tetrachloride; Cells, Cultured; Gene Expression Regula

2015
Contrast-enhanced ultrasound for quantitative assessment of portal pressure in canine liver fibrosis.
    World journal of gastroenterology, 2015, Apr-21, Volume: 21, Issue:15

    Topics: Animals; Area Under Curve; Biopsy; Blood Flow Velocity; Blood Pressure Determination; Carbon Tetrach

2015
MiR-22 Suppresses BMP7 in the Development of Cirrhosis.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 36, Issue:3

    Topics: 3' Untranslated Regions; Adult; Animals; Bone Morphogenetic Protein 7; Carbon Tetrachloride; Dependo

2015
IGF-1 decreases portal vein endotoxin via regulating intestinal tight junctions and plays a role in attenuating portal hypertension of cirrhotic rats.
    BMC gastroenterology, 2015, Jul-08, Volume: 15

    Topics: Animals; Apoptosis; Caco-2 Cells; Carbon Tetrachloride; Claudin-1; Endotoxins; Humans; Hypertension,

2015
Janus-kinase-2 relates directly to portal hypertension and to complications in rodent and human cirrhosis.
    Gut, 2017, Volume: 66, Issue:1

    Topics: Adult; Animals; Carbon Tetrachloride; Collagen; Enzyme Inhibitors; Female; Hepatic Stellate Cells; H

2017
Role of estrogen receptor β selective agonist in ameliorating portal hypertension in rats with CCl4-induced liver cirrhosis.
    World journal of gastroenterology, 2016, May-14, Volume: 22, Issue:18

    Topics: Actins; Animals; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cycl

2016
Dihydroartemisinin counteracts fibrotic portal hypertension via farnesoid X receptor-dependent inhibition of hepatic stellate cell contraction.
    The FEBS journal, 2017, Volume: 284, Issue:1

    Topics: Animals; Artemisinins; Carbon Tetrachloride; Cell Death; Chenodeoxycholic Acid; Gene Expression; Hep

2017
Effects of Nuclear Factor-E2-related factor 2/Heme Oxygenase 1 on splanchnic hemodynamics in experimental cirrhosis with portal hypertension.
    Microvascular research, 2017, Volume: 111

    Topics: Animals; Arterioles; Carbon Tetrachloride; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Hemodyna

2017
Three-day tetrahydrobiopterin therapy increases in vivo hepatic NOS activity and reduces portal pressure in CCl4 cirrhotic rats.
    Journal of hepatology, 2008, Volume: 49, Issue:2

    Topics: Animals; Biopterins; Carbon Tetrachloride; Cyclic GMP; Enzyme Inhibitors; Hypertension, Portal; Hypo

2008
Comparison of three research models of portal hypertension in mice: macroscopic, histological and portal pressure evaluation.
    International journal of experimental pathology, 2008, Volume: 89, Issue:4

    Topics: Animals; Ascites; Carbon Tetrachloride; Common Bile Duct; Disease Progression; Hypertension, Portal;

2008
Superoxide dismutase gene transfer reduces portal pressure in CCl4 cirrhotic rats with portal hypertension.
    Gut, 2009, Volume: 58, Issue:1

    Topics: Adenoviridae; Animals; Carbon Tetrachloride; Endothelium, Vascular; Gene Transfer Techniques; Geneti

2009
Early propranolol administration does not prevent development of esophageal varices in cirrhotic rats.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2009, Volume: 42, Issue:1

    Topics: Animals; Carbon Tetrachloride; Esophageal and Gastric Varices; Hypertension, Portal; Liver Cirrhosis

2009
Combined use of propranolol and nifedipine offers better effects on portal vein nonuniform remodeling in carbon tetrachloride (CCl(4))-induced portal hypertensive rats.
    European journal of pharmacology, 2009, Jun-24, Volume: 613, Issue:1-3

    Topics: Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Carbon Tetrachloride; Drug Combinati

2009
Bile-acid-activated farnesoid X receptor regulates hydrogen sulfide production and hepatic microcirculation.
    World journal of gastroenterology, 2009, May-07, Volume: 15, Issue:17

    Topics: Adrenergic alpha-Agonists; Animals; Base Sequence; Bile Acids and Salts; Carbon Tetrachloride; Cell

2009
Overexpression of beta-catenin is responsible for the development of portal hypertension during liver cirrhosis.
    Anatomical record (Hoboken, N.J. : 2007), 2009, Volume: 292, Issue:6

    Topics: Adenoviridae; Animals; beta Catenin; Carbon Tetrachloride; Disease Models, Animal; Disease Progressi

2009
Vascular hyporesponsiveness to angiotensin II in rats with CCl(4)-induced liver cirrhosis.
    European journal of clinical investigation, 2009, Volume: 39, Issue:10

    Topics: Angiotensin II; Animals; Aorta; Blotting, Western; Carbon Tetrachloride; Hypertension, Portal; Liver

2009
Role of endothelial nitric oxide synthase in the development of portal hypertension in the carbon tetrachloride-induced liver fibrosis model.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:4

    Topics: Alanine Transaminase; Animals; Aorta, Abdominal; Carbon Tetrachloride; Genotype; Hyperemia; Hyperten

2009
Alterations in mechanical properties of mesenteric resistance arteries in experimental portal hypertension.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:4

    Topics: Animals; Biomechanical Phenomena; Blood Pressure; Carbon Tetrachloride; Elasticity; Hypertension, Po

2009
A novel model of CCl4-induced cirrhosis with ascites in the mouse.
    Journal of hepatology, 2009, Volume: 51, Issue:6

    Topics: Administration, Inhalation; Animals; Ascites; Carbon Tetrachloride; Cytokines; Disease Models, Anima

2009
Vascular corrosion casting: analyzing wall shear stress in the portal vein and vascular abnormalities in portal hypertensive and cirrhotic rodents.
    Laboratory investigation; a journal of technical methods and pathology, 2010, Volume: 90, Issue:11

    Topics: Animals; Carbon Tetrachloride; Corrosion Casting; Hypertension, Portal; Liver; Liver Cirrhosis, Expe

2010
Increased myoendothelial gap junctions mediate the enhanced response to epoxyeicosatrienoic acid and acetylcholine in mesenteric arterial vessels of cirrhotic rats.
    Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31, Issue:6

    Topics: 8,11,14-Eicosatrienoic Acid; Acetylcholine; Analysis of Variance; Animals; Carbon Tetrachloride; Con

2011
11,12-EET increases porto-sinusoidal resistance and may play a role in endothelial dysfunction of portal hypertension.
    Prostaglandins & other lipid mediators, 2011, Volume: 96, Issue:1-4

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Carbon Tetrachloride; Cytochrome P-450 Enzym

2011
Hydrogen sulfide attenuates carbon tetrachloride-induced hepatotoxicity, liver cirrhosis and portal hypertension in rats.
    PloS one, 2011, Volume: 6, Issue:10

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Pressure; Carbon Tetrachloride; Cy

2011
Intestinal bacterial translocation in rats with cirrhosis is related to compromised Paneth cell antimicrobial host defense.
    Hepatology (Baltimore, Md.), 2012, Volume: 55, Issue:4

    Topics: Animals; Bacterial Translocation; Bacteroides fragilis; beta-Defensins; Bifidobacterium; Carbon Tetr

2012
Morphological and biomechanical remodeling of the hepatic portal vein in a swine model of portal hypertension.
    Annals of vascular surgery, 2012, Volume: 26, Issue:2

    Topics: Animals; Biomechanical Phenomena; Carbon Tetrachloride; Compliance; Down-Regulation; Elastic Modulus

2012
PPARα activation improves endothelial dysfunction and reduces fibrosis and portal pressure in cirrhotic rats.
    Journal of hepatology, 2012, Volume: 56, Issue:5

    Topics: Animals; Blood Pressure; Carbon Tetrachloride; Cyclooxygenase 1; Disease Models, Animal; Endothelium

2012
Droxidopa, an oral norepinephrine precursor, improves hemodynamic and renal alterations of portal hypertensive rats.
    Hepatology (Baltimore, Md.), 2012, Volume: 56, Issue:5

    Topics: Animals; Antiparkinson Agents; Bile Ducts; Blood Pressure; Carbidopa; Carbon Tetrachloride; Disease

2012
Transplantation of endothelial progenitor cells ameliorates vascular dysfunction and portal hypertension in carbon tetrachloride-induced rat liver cirrhotic model.
    Journal of gastroenterology and hepatology, 2013, Volume: 28, Issue:1

    Topics: Animals; Blood Vessels; Carbon Tetrachloride; Caveolins; Cell Proliferation; Endothelial Cells; Endo

2013
Recombinant human manganese superoxide dismutase reduces liver fibrosis and portal pressure in CCl4-cirrhotic rats.
    Journal of hepatology, 2013, Volume: 58, Issue:2

    Topics: Animals; Carbon Tetrachloride; Disease Models, Animal; Hypertension, Portal; Liver Cirrhosis; Male;

2013
Dysbalance in sympathetic neurotransmitter release and action in cirrhotic rats: impact of exogenous neuropeptide Y.
    Journal of hepatology, 2013, Volume: 58, Issue:2

    Topics: Animals; Carbon Tetrachloride; Disease Models, Animal; Electric Stimulation; Hypertension, Portal; L

2013
[The anti-portal hypertension effect of oleanolic acid in CCl4-induced cirrhosis rats].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2012, Volume: 35, Issue:6

    Topics: Animals; Body Weight; Carbon Tetrachloride; Disease Models, Animal; Hypertension, Portal; Liver; Liv

2012
Resveratrol improves intrahepatic endothelial dysfunction and reduces hepatic fibrosis and portal pressure in cirrhotic rats.
    Journal of hepatology, 2013, Volume: 58, Issue:5

    Topics: Animals; Antioxidants; Carbon Tetrachloride; Disease Models, Animal; Dose-Response Relationship, Dru

2013
Zolmitriptan: a novel portal hypotensive agent which synergizes with propranolol in lowering portal pressure.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Body Weight; Carbon Tetrachloride; Ca

2013
Hemodynamic and antifibrotic effects of losartan in rats with liver fibrosis and/or portal hypertension.
    Journal of hepatology, 2002, Volume: 37, Issue:6

    Topics: Alanine Transaminase; Alkaline Phosphatase; Angiotensin Receptor Antagonists; Animals; Bile Ducts; B

2002
Intestinal mucosal oxidative damage and bacterial translocation in cirrhotic rats.
    European journal of gastroenterology & hepatology, 2003, Volume: 15, Issue:2

    Topics: Animals; Bacterial Translocation; Biomarkers; Carbon Tetrachloride; Cecum; Enterococcus faecalis; En

2003
[Effects of ET-1 on isolated perfused rat liver and vascular rings at two stages of cirrhosis].
    Zhonghua yi xue za zhi, 2002, Nov-25, Volume: 82, Issue:22

    Topics: Animals; Carbon Tetrachloride; Dose-Response Relationship, Drug; Endothelin-1; Hypertension, Portal;

2002
Hepatic osteodystrophy in rats results mainly from portasystemic shunting.
    Gut, 2003, Volume: 52, Issue:4

    Topics: Absorptiometry, Photon; Animals; Bone Density; Carbon Tetrachloride; Disease Models, Animal; Female;

2003
Salviae miltiorrhizae ameliorates cirrhosis and portal hypertension by inhibiting nitric oxide in cirrhotic rats.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2003, Volume: 2, Issue:3

    Topics: Animals; Carbon Tetrachloride; Drugs, Chinese Herbal; Hypertension, Portal; Liver; Liver Circulation

2003
[Experimental study on iNOS gene transfer mediated by liposome to treat portal hypertension in cirrhotic rats].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2004, Apr-07, Volume: 42, Issue:7

    Topics: Animals; Carbon Tetrachloride; Disease Models, Animal; Hypertension, Portal; Immunohistochemistry; L

2004
Endothelin receptor antagonist TAK-044 arrests and reverses the development of carbon tetrachloride induced cirrhosis in rats.
    Gut, 2004, Volume: 53, Issue:7

    Topics: Animals; Carbon Tetrachloride; Disease Progression; Endothelin Receptor Antagonists; Endothelin-1; H

2004
[Morphology of portal hypertension at the early stage of liver damage induced by CCl4: an experimental study with dogs].
    Zhonghua yi xue za zhi, 2004, Jul-02, Volume: 84, Issue:13

    Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur

2004
Neutral endopeptidase (EC 3.4.24.11) in cirrhotic liver: a new target to treat portal hypertension?
    Journal of hepatology, 2005, Volume: 43, Issue:5

    Topics: Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Pressure; Carbon Tetrachloride; Cycl

2005
[Influence of platelet activating factor and its antagonist on portal hypertension associated with liver cirrhosis: an experiment with rats].
    Zhonghua yi xue za zhi, 2005, Dec-14, Volume: 85, Issue:47

    Topics: Animals; Carbon Tetrachloride; Ginkgolides; Hypertension, Portal; Injections, Intravenous; Lactones;

2005
Intestinal permeability in rats with CCl4-induced portal hypertension.
    World journal of gastroenterology, 2006, Jan-21, Volume: 12, Issue:3

    Topics: Animals; Carbon Tetrachloride; Endotoxins; Escherichia coli; Humans; Hypertension, Portal; Intestina

2006
Effect of increased hepatic platelet activating factor and its receptor portal hypertension in CCl4-induced liver cirrhosis.
    World journal of gastroenterology, 2006, Feb-07, Volume: 12, Issue:5

    Topics: Animals; Base Sequence; Blood Pressure; Carbon Tetrachloride; Diterpenes; Ginkgolides; Hypertension,

2006
[Akt gene therapy for cirrhotic rats with portal hypertension].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2008, Volume: 33, Issue:1

    Topics: Adenoviridae; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Genetic Therapy; Hypert

2008
Down-regulation of genes related to the adrenergic system may contribute to splanchnic vasodilation in rat portal hypertension.
    Journal of hepatology, 2008, Volume: 49, Issue:1

    Topics: Animals; Carbon Tetrachloride; Disease Models, Animal; Dopamine beta-Hydroxylase; Down-Regulation; G

2008
Role of cirrhosis in the hemodynamic response to hemorrhage in portal hypertension.
    Surgery, 1995, Volume: 117, Issue:5

    Topics: Animals; Carbon Tetrachloride; Common Bile Duct; Hemodynamics; Hemorrhage; Hypertension, Portal; Lig

1995
Impaired function of pancreatic islets from rats with portal hypertension resulting from cirrhosis and partial portal vein ligation.
    Hepatology (Baltimore, Md.), 1994, Volume: 19, Issue:5

    Topics: Animals; Carbon Tetrachloride; Glucagon; Hypertension, Portal; In Vitro Techniques; Insulin; Insulin

1994
Increased capillary endothelial leakage in portal hypertensive gastric mucosa: fluorescence microscopy in CCl4-induced cirrhotic rats.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1995, Volume: 195, Issue:3

    Topics: Albumins; Animals; Carbon Tetrachloride; Cell Membrane Permeability; Endothelium, Vascular; Fluoresc

1995
[99mTc-MIBI used for diagnosis of portal hypertension: an experimental study].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1995, Volume: 33, Issue:12

    Topics: Administration, Rectal; Animals; Carbon Tetrachloride; Heart; Hypertension, Portal; Injections, Intr

1995
Comparison of vascular nitric oxide production and systemic hemodynamics in cirrhosis versus prehepatic portal hypertension in rats.
    Hepatology (Baltimore, Md.), 1996, Volume: 24, Issue:4

    Topics: Animals; Aorta; Ascites; Carbon Tetrachloride; Cyclic GMP; Hemodynamics; Hypertension, Portal; Ligat

1996
The cytoprotective effect of iloprost against carbon tetrachloride induced necrosis in rat liver.
    Research communications in molecular pathology and pharmacology, 1997, Volume: 95, Issue:3

    Topics: Animals; Carbon Tetrachloride; Dinoprostone; Disease Models, Animal; Female; Histamine; Hypertension

1997
Tyrosine kinase inhibition ameliorates the hyperdynamic state and decreases nitric oxide production in cirrhotic rats with portal hypertension and ascites.
    The Journal of clinical investigation, 1997, Aug-01, Volume: 100, Issue:3

    Topics: Animals; Ascites; Benzylidene Compounds; Carbon Tetrachloride; Enzyme Inhibitors; Hypertension, Port

1997
Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: endothelial dysfunction in portal hypertension.
    Gastroenterology, 1998, Volume: 114, Issue:2

    Topics: Animals; Carbon Tetrachloride; Endothelium; Hypertension, Portal; Kupffer Cells; Ligation; Liver; Li

1998
An endothelin receptor antagonist TAK-044 ameliorates carbon tetrachloride-induced acute liver injury and portal hypertension in rats.
    Liver, 1998, Volume: 18, Issue:1

    Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Hyper

1998
Chronic administration of octreotide ameliorates portal hypertension and portal hypertensive gastropathy in rats with cirrhosis.
    Clinical science (London, England : 1979), 1998, Volume: 94, Issue:4

    Topics: Animals; Carbon Tetrachloride; Gastric Mucosa; Gastrointestinal Agents; Hypertension, Portal; Liver

1998
Endothelin-induced contraction of the portal vein in cirrhosis.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1999, Volume: 31, Issue:3

    Topics: Animals; Carbon Tetrachloride; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-3; Hyperte

1999
Spleno-renal shunt blood flow is an accurate index of collateral circulation in different models of portal hypertension and after pharmacological changes in rats.
    Journal of hepatology, 2000, Volume: 32, Issue:3

    Topics: Animals; Carbon Tetrachloride; Collateral Circulation; Dimethylnitrosamine; Disease Models, Animal;

2000
Portal hypertensive response to bradykinin in inflamed or cirrhotic rat livers is mediated by B2-type receptors.
    Journal of gastroenterology and hepatology, 2001, Volume: 16, Issue:1

    Topics: Analysis of Variance; Animals; Bradykinin; Carbon Tetrachloride; Hypertension, Portal; Inflammation;

2001
A rat model of liver cirrhosis and esophageal varices.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 2001, Volume: 200, Issue:3

    Topics: Animals; Carbon Tetrachloride; Collateral Circulation; Disease Models, Animal; Esophageal and Gastri

2001
NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Jul-17, Volume: 98, Issue:15

    Topics: Animals; Carbon Tetrachloride; Collagen; Hypertension, Portal; Liver; Liver Cirrhosis; Male; Nitrate

2001
Adenosine reverses a preestablished CCl4-induced micronodular cirrhosis through enhancing collagenolytic activity and stimulating hepatocyte cell proliferation in rats.
    Hepatology (Baltimore, Md.), 2001, Volume: 34, Issue:4 Pt 1

    Topics: Adenosine; Animals; Carbon Tetrachloride; Cell Division; Collagen; DNA; Fibronectins; Hepatocytes; H

2001
[The role of nitric oxide in hyperdynamic circulation in portal hypertensive rats].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1998, Volume: 36, Issue:3

    Topics: Animals; Arginine; Carbon Tetrachloride; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Hy

1998
Effects of endothelin in portal hypertensive rats.
    Clinical science (London, England : 1979), 1992, Volume: 83, Issue:2

    Topics: Animals; Blood Pressure; Carbon Tetrachloride; Cardiovascular System; Dose-Response Relationship, Dr

1992
[Effects of spleen on inducing portal hypertension and liver cirrhosis in rats].
    Zhonghua yi xue za zhi, 1992, Volume: 72, Issue:6

    Topics: Animals; Carbon Tetrachloride; Ethanol; Hypertension, Portal; Liver Cirrhosis, Experimental; Male; R

1992
Gastric mucosal blood flow distribution in the CCl4-induced cirrhotic rat--a model of portal hypertensive gastropathy?
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1992, Volume: 192, Issue:5

    Topics: Animals; Blood Flow Velocity; Carbon Tetrachloride; Disease Models, Animal; Gastric Mucosa; Hyperten

1992
The effect of alcohol-induced hepatomegaly on portal hypertension in cirrhotic rats.
    Journal of hepatology, 1992, Volume: 15, Issue:1-2

    Topics: Animals; Blood Pressure; Carbon Tetrachloride; Collagen; Ethanol; Hemodynamics; Hepatomegaly; Hypert

1992
Alterations of intestinal lymphatic system and mucosal immunity in CCl4-induced portal hypertensive rats.
    Journal of gastroenterology and hepatology, 1989, Volume: 4 Suppl 1

    Topics: Animals; Carbon Tetrachloride; Hypertension, Portal; Intestinal Mucosa; Intestine, Small; Liver Cirr

1989
Hemodynamic effects of blood volume restitution following a hemorrhage in rats with portal hypertension due to cirrhosis of the liver: influence of the extent of portal-systemic shunting.
    Hepatology (Baltimore, Md.), 1989, Volume: 9, Issue:6

    Topics: Animals; Blood Volume; Carbon Tetrachloride; Collateral Circulation; Hemodynamics; Hemorrhage; Hyper

1989
Gastric secretion in canines with cirrhosis and ascites.
    Surgery, gynecology & obstetrics, 1969, Volume: 129, Issue:4

    Topics: Animals; Ascites; Carbon Tetrachloride; Catheterization; Dogs; Female; Gastric Juice; Gastric Mucosa

1969
Instant cirrhosis. An improved method for producing cirrhosis of the liver in rats by simultaneous administration of carbon tetrachloride and phenobarbitone.
    British journal of experimental pathology, 1969, Volume: 50, Issue:5

    Topics: Animals; Ascites; Carbon Tetrachloride; Gases; Hypertension, Portal; Liver Cirrhosis, Experimental;

1969
Effect of liver regeneration on the portal pressure and vascular pattern in normal and cirrhotic rats.
    The Journal of pathology and bacteriology, 1968, Volume: 96, Issue:2

    Topics: Animals; Blood Pressure Determination; Carbon Tetrachloride; Collagen; DNA; Hepatectomy; Hypertensio

1968
Portal hypertension in acute experimental veno-occlusive disease of the liver in rats.
    British journal of experimental pathology, 1969, Volume: 50, Issue:1

    Topics: Anesthesia, Inhalation; Animals; Blood Pressure Determination; Carbon Tetrachloride; Chemical and Dr

1969
A composite canine model of cirrhosis.
    Annals of surgery, 1969, Volume: 169, Issue:4

    Topics: Animals; Ascites; Blood Pressure; Carbon Tetrachloride; Dogs; Hypertension, Portal; Liver; Liver Cir

1969