carbon tetrachloride has been researched along with Chronic Disease in 84 studies
Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Then, we examined possible in vivo hepatoprotective effects of EP extract on mouse models of carbon tetrachloride (CCl4)-induced chronic and acute liver failure." | 7.80 | Protective effects of Ephedra pachyclada extract on mouse models of carbon tetrachloride- induced chronic and acute liver failure. ( Azarnia, M; Ghasemi, M; Jamali, M; Mirabolghasemi, G; Naghizadeh, MM; Nazarian, S; Rajabi, M; Tahamtani, Y, 2014) |
| "The influence of chronic hepatic failure on the disposition kinetics of valproate (VPA) excretion via a phase II reaction was examined in rats treated with carbon tetrachloride (1." | 7.74 | Influence of chronic hepatic failure on disposition kinetics of valproate excretion through a phase II reaction in rats treated with carbon tetrachloride. ( Ishizaki, J; Khemawoot, P; Maruyama, C; Miyamoto, K; Noda, H; Tsukada, H; Yokogawa, K, 2007) |
| " Hepatic fibrosis was induced in CD248(-/-) and wild-type controls with carbon tetrachloride (CCl4) treatment." | 3.83 | CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism. ( Aldridge, V; Buckley, CD; Croft, AP; Fear, J; Garg, A; Haldar, D; Hedegaard, D; Henderson, NC; Naylor, AJ; Newsome, PN; Reynolds, GM; Weston, CJ; Wilhelm, A, 2016) |
| " Then, we examined possible in vivo hepatoprotective effects of EP extract on mouse models of carbon tetrachloride (CCl4)-induced chronic and acute liver failure." | 3.80 | Protective effects of Ephedra pachyclada extract on mouse models of carbon tetrachloride- induced chronic and acute liver failure. ( Azarnia, M; Ghasemi, M; Jamali, M; Mirabolghasemi, G; Naghizadeh, MM; Nazarian, S; Rajabi, M; Tahamtani, Y, 2014) |
| " After acetaminophen intoxication, necrosis was significantly increased in TAFI-/- mice at 24 hours (h) after injection." | 3.79 | TAFI deficiency promotes liver damage in murine models of liver failure through defective down-regulation of hepatic inflammation. ( Adelmeijer, J; Hugenholtz, GC; Lisman, T; Meijers, JC; Porte, RJ, 2013) |
| " plantarum strains were administered in ornithine transcarbamoylase-deficient Sparse-fur mice, a model of constitutive hyperammonemia, in a carbon tetrachloride rat model of chronic liver insufficiency and in a thioacetamide-induced acute liver failure mice model." | 3.74 | Control of acute, chronic, and constitutive hyperammonemia by wild-type and genetically engineered Lactobacillus plantarum in rodents. ( Demetter, P; Devière, J; Goffin, P; Gustot, T; Hols, P; Moreno, C; Nicaise, C; Prozzi, D; Quertinmont, E; Suain, V; Viaene, E, 2008) |
| "The influence of chronic hepatic failure on the disposition kinetics of valproate (VPA) excretion via a phase II reaction was examined in rats treated with carbon tetrachloride (1." | 3.74 | Influence of chronic hepatic failure on disposition kinetics of valproate excretion through a phase II reaction in rats treated with carbon tetrachloride. ( Ishizaki, J; Khemawoot, P; Maruyama, C; Miyamoto, K; Noda, H; Tsukada, H; Yokogawa, K, 2007) |
| "Obesity is associated with hyperleptinemia and is also a risk factor for fibrosis and severity of fibrosis in several chronic liver diseases." | 3.71 | Leptin is essential for the hepatic fibrogenic response to chronic liver injury. ( Farrell, GC; Leclercq, IA; Robertson, GR; Schriemer, R, 2002) |
| "Using the carbon tetrachloride liver cirrhosis rat model, the protective effect of the green tea extractive (GTE) on the liver cirrhosis was studied." | 3.71 | [Green tea extracts protected against carbon tetrachloride-induced chronic liver damage and cirrhosis]. ( Lu, R; Shen, X; Wu, M; Xiao, J, 2002) |
| "Most adverse drug reactions affecting the liver and producing jaundice are unpredictable, delayed in onset, and only hypothetically related to microsomal metabolism in some instances." | 2.35 | Hepatic drug metabolism and adverse hepatic drug reactions. ( Schaffner, F, 1975) |
| "TGF-β signaling links HSC activation to liver fibrosis and tumorigenesis." | 1.62 | Perivenous Stellate Cells Are the Main Source of Myofibroblasts and Cancer-Associated Fibroblasts Formed After Chronic Liver Injuries. ( Ge, G; Lin, M; Peng, YJ; Ren, Z; Shang, G; Tang, XT; Wang, SS; Yin, X; Yuan, J; Zhou, BO, 2021) |
| "Different stages of liver fibrosis were induced in wild-type and NS3/4A-Tg mice by single carbon tetrachloride (acute) or multiple injections for 4 (intermediate) or 8 (chronic) weeks." | 1.42 | Hepatitis C Virus Nonstructural 3/4A Protein Dampens Inflammation and Contributes to Slow Fibrosis Progression during Chronic Fibrosis In Vivo. ( Bansal, R; Brenndörfer, ED; Frelin, L; Prakash, J; Sällberg, M; Storm, G, 2015) |
| "In the present study, liver fibrosis was induced in wild-type (WT), TLR7-deficient, and IFN-α/β receptor-1 (IFNAR1)-deficient mice and TLR7-mediated signaling was assessed in liver cells isolated from these mice." | 1.40 | Toll-like receptor 7-mediated type I interferon signaling prevents cholestasis- and hepatotoxin-induced liver fibrosis. ( Kim, B; Kim, JW; Lim, CW; Park, S; Roh, YS; Seki, E, 2014) |
| "Phenacetin metabolism was impaired more severely in 6 rats that died than in 21 living rats (P < 0." | 1.38 | Phenacetin O-deethylation is a useful tool for evaluation of hepatic functional reserve in rats with CCl(4)-induced chronic liver injury. ( Cai, M; He, P; Li, X; Liu, Z; Qu, Z; Wang, X; Xiao, J; Zhou, M, 2012) |
| "Liver samples from patients with liver fibrosis and from mice treated by either carbon tetrachloride (CCl(4)) or thioacetamide (TAA) were evaluated for mRNA expression of Snail1." | 1.37 | Snail1 transcription factor is a critical mediator of hepatic stellate cell activation following hepatic injury. ( Brun, P; Buda, A; Castagliuolo, I; De Caro, R; Fabris, P; Giordani, MT; Grillo, AR; Macchi, V; Martines, D; Palù, G; Scarpa, M; Signori, S; Stefani, A, 2011) |
| "Hydroxysafflor yellow A (HSYA) was isolated from the dried flower of Carthamus tinctorius L." | 1.37 | Hydroxysafflor yellow A protects against chronic carbon tetrachloride-induced liver fibrosis. ( Dong, H; Guo, J; Li, X; Liu, J; Niu, Y; Zhang, Y; Zhao, X; Zhou, L, 2011) |
| " To address this issue, we induced liver fibrosis by carbon tetrachloride (CCl(4)) chronic administration to 8-week- and 15-month-old mice." | 1.37 | Increased susceptibility to liver fibrosis with age is correlated with an altered inflammatory response. ( Abdoun, E; Collin de l'Hortet, A; Cosson, C; Fromenty, B; Gilgenkrantz, H; Guidotti, JE; Mahrouf-Yorgov, M; Mitchell, C; Slama, A, 2011) |
| "Liver cirrhosis was induced by intraperitoneal administration of CCl4 at a dose of 0." | 1.33 | Cryopreserved fetal liver cell transplants support the chronic failing liver in rats with CCl4-induced cirrhosis. ( Fuller, BJ; Mazur, SP; Ochenashko, OV; Petrenko, AY; Somov, AY; Volkova, NA, 2006) |
| " In this study, we searched for new biochemical indicators that correlate with hepatic function and tried to simulate appropriate drug dosage in chronic hepatic failure." | 1.33 | Development of dosage design of hepatic metabolizing drugs using serum albumin level in chronic hepatic failure. ( Kurihara, T; Mano, Y; Miyamoto, K; Nomura, M; Tsukada, H; Yokogawa, K, 2006) |
| "Carbon tetrachloride (CCl4) was intraperitoneally injected into Balb/c mice 4 times at biweekly intervals, and the morphological changes of the liver and kidney were examined during 12 weeks after the last injection." | 1.28 | Study on chronic renal injuries induced by carbon tetrachloride: selective inhibition of the nephrotoxicity by irradiation. ( Azemoto, R; Makino, Y; Mori, T; Mori, Y; Ogawa, M; Ohto, M; Ueda, S; Wakashin, M; Wakashin, Y; Yoshida, H, 1992) |
| "Colchicine treatment prevented the modifications in ATPases when given simultaneously with CCl4 and reverted the alterations in ATPase activities of the CCl4-cirrhotic animals." | 1.27 | Cryptic adenosine triphosphatase activities in plasma membranes of CCl4-cirrhotic rats. Its modulation by changes in cholesterol/phospholipid ratios. ( Amaya, A; Mourelle, M; Rojkind, M; Yahuaca, P, 1985) |
| "In rats the effect of a chronic administration of CCl4 on the excretion and disstribution of 64Cu, 65Zn, and 203Hg was investigated." | 1.25 | Biliary excretion of 64Cu, 65Zn and 203Hg in the rat with liver injury induced by CCl4. ( Cikrt, M; Holusa, R; Tichý, M, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (23.81) | 18.7374 |
| 1990's | 10 (11.90) | 18.2507 |
| 2000's | 20 (23.81) | 29.6817 |
| 2010's | 29 (34.52) | 24.3611 |
| 2020's | 5 (5.95) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, X | 1 |
| Yang, L | 2 |
| Fan, X | 1 |
| Zhao, X | 2 |
| Chang, N | 1 |
| Li, L | 1 |
| Hu, Z | 1 |
| Su, H | 1 |
| Zeng, Y | 1 |
| Lin, C | 1 |
| Guo, Z | 1 |
| Zhong, F | 1 |
| Jiang, K | 1 |
| Yuan, G | 1 |
| He, S | 1 |
| Ding, H | 1 |
| Fang, M | 1 |
| Gong, Y | 1 |
| Li, D | 1 |
| Zhang, C | 1 |
| Wen, G | 1 |
| Wu, C | 1 |
| Yang, J | 1 |
| Yang, Y | 1 |
| Yan, Y | 1 |
| Wang, R | 1 |
| Hu, X | 1 |
| Wang, S | 2 |
| Zhang, L | 2 |
| Hou, C | 1 |
| Wang, SS | 1 |
| Tang, XT | 1 |
| Lin, M | 1 |
| Yuan, J | 1 |
| Peng, YJ | 1 |
| Yin, X | 1 |
| Shang, G | 1 |
| Ge, G | 1 |
| Ren, Z | 1 |
| Zhou, BO | 1 |
| Li, X | 3 |
| Yao, QY | 1 |
| Liu, HC | 1 |
| Jin, QW | 1 |
| Xu, BL | 1 |
| Zhang, SC | 1 |
| Tu, CT | 1 |
| Perazzoli, MR | 1 |
| Perondi, CK | 1 |
| Baratto, CM | 1 |
| Winter, E | 1 |
| Creczynski-Pasa, TB | 1 |
| Locatelli, C | 1 |
| Chung, HK | 1 |
| Kim, JT | 1 |
| Kim, HW | 1 |
| Kwon, M | 1 |
| Kim, SY | 1 |
| Shong, M | 1 |
| Kim, KS | 1 |
| Yi, HS | 1 |
| Manco, R | 1 |
| Clerbaux, LA | 1 |
| Verhulst, S | 1 |
| Bou Nader, M | 1 |
| Sempoux, C | 1 |
| Ambroise, J | 1 |
| Bearzatto, B | 1 |
| Gala, JL | 1 |
| Horsmans, Y | 1 |
| van Grunsven, L | 1 |
| Desdouets, C | 1 |
| Leclercq, I | 1 |
| Hugenholtz, GC | 1 |
| Meijers, JC | 1 |
| Adelmeijer, J | 1 |
| Porte, RJ | 1 |
| Lisman, T | 1 |
| Huan, SK | 1 |
| Wang, KT | 1 |
| Lee, CJ | 1 |
| Sung, CH | 1 |
| Chien, TY | 1 |
| Wang, CC | 1 |
| Ding, BS | 1 |
| Cao, Z | 1 |
| Lis, R | 1 |
| Nolan, DJ | 1 |
| Guo, P | 1 |
| Simons, M | 1 |
| Penfold, ME | 1 |
| Shido, K | 1 |
| Rabbany, SY | 1 |
| Rafii, S | 1 |
| Roh, YS | 1 |
| Park, S | 1 |
| Kim, JW | 1 |
| Lim, CW | 1 |
| Seki, E | 1 |
| Kim, B | 1 |
| Ghasemi, M | 1 |
| Azarnia, M | 1 |
| Jamali, M | 1 |
| Mirabolghasemi, G | 1 |
| Nazarian, S | 1 |
| Naghizadeh, MM | 1 |
| Rajabi, M | 1 |
| Tahamtani, Y | 1 |
| Sakai, K | 2 |
| Jawaid, S | 1 |
| Sasaki, T | 2 |
| Bou-Gharios, G | 1 |
| Sakai, T | 2 |
| Bárcena, C | 1 |
| Stefanovic, M | 1 |
| Tutusaus, A | 1 |
| Joannas, L | 1 |
| Menéndez, A | 1 |
| García-Ruiz, C | 1 |
| Sancho-Bru, P | 1 |
| Marí, M | 1 |
| Caballeria, J | 1 |
| Rothlin, CV | 1 |
| Fernández-Checa, JC | 1 |
| de Frutos, PG | 1 |
| Morales, A | 1 |
| Bansal, R | 1 |
| Frelin, L | 1 |
| Brenndörfer, ED | 1 |
| Storm, G | 1 |
| Prakash, J | 1 |
| Sällberg, M | 1 |
| Wilhelm, A | 1 |
| Aldridge, V | 1 |
| Haldar, D | 1 |
| Naylor, AJ | 1 |
| Weston, CJ | 1 |
| Hedegaard, D | 1 |
| Garg, A | 1 |
| Fear, J | 1 |
| Reynolds, GM | 1 |
| Croft, AP | 1 |
| Henderson, NC | 1 |
| Buckley, CD | 1 |
| Newsome, PN | 1 |
| Wilson, CL | 1 |
| Murphy, LB | 1 |
| Leslie, J | 1 |
| Kendrick, S | 1 |
| French, J | 1 |
| Fox, CR | 1 |
| Sheerin, NS | 1 |
| Fisher, A | 1 |
| Robinson, JH | 1 |
| Tiniakos, DG | 1 |
| Gray, DA | 1 |
| Oakley, F | 1 |
| Mann, DA | 1 |
| Iwasaki, A | 1 |
| Moriya, K | 1 |
| Keene, DR | 1 |
| Akhtar, R | 1 |
| Miyazono, T | 1 |
| Yasumura, S | 1 |
| Watanabe, M | 1 |
| Morishita, S | 1 |
| Huang, B | 1 |
| Cheng, X | 1 |
| Wang, H | 2 |
| Huang, W | 1 |
| la Ga Hu, Z | 1 |
| Wang, D | 1 |
| Zhang, K | 1 |
| Zhang, H | 2 |
| Xue, Z | 1 |
| Da, Y | 1 |
| Zhang, N | 1 |
| Hu, Y | 1 |
| Yao, Z | 1 |
| Qiao, L | 1 |
| Gao, F | 1 |
| Zhang, R | 1 |
| Hyun, J | 1 |
| Kim, J | 1 |
| Rao, KM | 1 |
| Park, SY | 1 |
| Chung, I | 1 |
| Ha, CS | 1 |
| Kim, SW | 1 |
| Yun, YH | 1 |
| Jung, Y | 1 |
| Kopec, AK | 1 |
| Joshi, N | 1 |
| Luyendyk, JP | 1 |
| Wang, JP | 1 |
| Sun, DX | 1 |
| Li, BS | 1 |
| Kang, FB | 1 |
| Guo, ZR | 1 |
| Li, MR | 1 |
| Kang, JW | 1 |
| Li, WY | 1 |
| Bezborodkina, NN | 1 |
| Okovityĭ, SV | 1 |
| Kudriavtseva, MV | 1 |
| Kirik, OV | 1 |
| Zarubina, IV | 1 |
| Kudriavtsev, BN | 1 |
| Nicaise, C | 1 |
| Prozzi, D | 1 |
| Viaene, E | 1 |
| Moreno, C | 1 |
| Gustot, T | 1 |
| Quertinmont, E | 1 |
| Demetter, P | 1 |
| Suain, V | 1 |
| Goffin, P | 1 |
| Devière, J | 1 |
| Hols, P | 1 |
| Dang, SS | 1 |
| Zhang, X | 1 |
| Jia, XL | 1 |
| Cheng, YA | 1 |
| Song, P | 1 |
| Liu, EQ | 1 |
| He, Q | 1 |
| Li, ZF | 1 |
| Yan, F | 1 |
| Zhang, QY | 1 |
| Jiao, L | 1 |
| Han, T | 1 |
| Qin, LP | 1 |
| Khalid, R | 1 |
| Irie, H | 1 |
| Asano-Hoshino, A | 1 |
| Sekino, Y | 1 |
| Nogami, M | 1 |
| Kitagawa, T | 1 |
| Kanda, H | 1 |
| Scarpa, M | 1 |
| Grillo, AR | 1 |
| Brun, P | 1 |
| Macchi, V | 1 |
| Stefani, A | 1 |
| Signori, S | 1 |
| Buda, A | 1 |
| Fabris, P | 1 |
| Giordani, MT | 1 |
| De Caro, R | 1 |
| Palù, G | 1 |
| Castagliuolo, I | 1 |
| Martines, D | 1 |
| Chávez, E | 1 |
| Castro-Sánchez, L | 1 |
| Shibayama, M | 2 |
| Tsutsumi, V | 2 |
| Pérez Salazar, E | 1 |
| Moreno, MG | 2 |
| Muriel, P | 2 |
| Zhang, Y | 1 |
| Guo, J | 1 |
| Dong, H | 1 |
| Zhou, L | 1 |
| Liu, J | 1 |
| Niu, Y | 1 |
| Mahrouf-Yorgov, M | 1 |
| Collin de l'Hortet, A | 1 |
| Cosson, C | 1 |
| Slama, A | 1 |
| Abdoun, E | 1 |
| Guidotti, JE | 1 |
| Fromenty, B | 1 |
| Mitchell, C | 1 |
| Gilgenkrantz, H | 1 |
| Aldaba-Muruato, LR | 1 |
| Li, W | 1 |
| Zhang, M | 1 |
| Zheng, YN | 1 |
| Li, J | 1 |
| Wang, YP | 1 |
| Wang, YJ | 1 |
| Gu, J | 1 |
| Jin, Y | 1 |
| Chen, L | 1 |
| Wang, JH | 1 |
| Choi, MK | 1 |
| Shin, JW | 1 |
| Hwang, SY | 1 |
| Son, CG | 1 |
| Liu, Z | 1 |
| Qu, Z | 1 |
| Cai, M | 1 |
| He, P | 1 |
| Zhou, M | 1 |
| Xiao, J | 2 |
| Wang, X | 1 |
| Kogure, T | 1 |
| Costinean, S | 1 |
| Yan, I | 1 |
| Braconi, C | 1 |
| Croce, C | 1 |
| Patel, T | 1 |
| Kuwahata, M | 1 |
| Kubota, H | 1 |
| Kanouchi, H | 1 |
| Ito, S | 1 |
| Ogawa, A | 1 |
| Kobayashi, Y | 1 |
| Kido, Y | 1 |
| Leclercq, IA | 1 |
| Farrell, GC | 1 |
| Schriemer, R | 1 |
| Robertson, GR | 1 |
| Lu, R | 1 |
| Shen, X | 1 |
| Wu, M | 1 |
| Liu, YK | 1 |
| Shen, W | 1 |
| Streetz, KL | 1 |
| Tacke, F | 1 |
| Leifeld, L | 1 |
| Wüstefeld, T | 1 |
| Graw, A | 1 |
| Klein, C | 1 |
| Kamino, K | 1 |
| Spengler, U | 1 |
| Kreipe, H | 1 |
| Kubicka, S | 1 |
| Müller, W | 1 |
| Manns, MP | 1 |
| Trautwein, C | 1 |
| MEYER-LEDDIN, H | 1 |
| CAGIANELLI, MA | 1 |
| SPREMOLLA, G | 1 |
| PIERI, N | 1 |
| Honda, T | 1 |
| Fukuda, Y | 1 |
| Nakano, I | 1 |
| Katano, Y | 1 |
| Goto, H | 1 |
| Nagasaki, M | 1 |
| Sato, Y | 1 |
| Murakami, T | 1 |
| Shimomura, Y | 1 |
| Orfila, C | 1 |
| Lepert, JC | 1 |
| Alric, L | 1 |
| Carrera, G | 1 |
| Béraud, M | 1 |
| Pipy, B | 1 |
| Titos, E | 1 |
| Clària, J | 1 |
| Planagumà, A | 1 |
| López-Parra, M | 1 |
| González-Périz, A | 1 |
| Gaya, J | 1 |
| Miquel, R | 1 |
| Arroyo, V | 1 |
| Rodés, J | 1 |
| Ochenashko, OV | 1 |
| Volkova, NA | 1 |
| Mazur, SP | 1 |
| Somov, AY | 1 |
| Fuller, BJ | 1 |
| Petrenko, AY | 1 |
| Mano, Y | 1 |
| Tsukada, H | 2 |
| Kurihara, T | 1 |
| Nomura, M | 1 |
| Yokogawa, K | 2 |
| Miyamoto, K | 2 |
| Khemawoot, P | 1 |
| Maruyama, C | 1 |
| Noda, H | 1 |
| Ishizaki, J | 1 |
| Hayashi, S | 1 |
| Itoh, A | 1 |
| Isoda, K | 1 |
| Kondoh, M | 1 |
| Kawase, M | 1 |
| Yagi, K | 1 |
| Leung, TM | 1 |
| Tipoe, GL | 1 |
| Liong, EC | 1 |
| Lau, TY | 1 |
| Fung, ML | 1 |
| Nanji, AA | 1 |
| Louria, DB | 1 |
| Bogden, JD | 1 |
| Hamazaki, K | 1 |
| Sato, S | 1 |
| Yunoki, M | 1 |
| Noda, T | 1 |
| Moreira, LF | 1 |
| Mimura, H | 1 |
| Orita, K | 1 |
| Koda, M | 1 |
| Murawaki, Y | 1 |
| Yamamoto, H | 1 |
| Kwasaki, H | 1 |
| Costa, LE | 1 |
| Llesuy, S | 1 |
| Boveris, A | 1 |
| Nakata, Y | 1 |
| Iwai, M | 1 |
| Kimura, S | 1 |
| Shimazu, T | 1 |
| Kreft, B | 2 |
| Block, W | 2 |
| Dombrowski, F | 2 |
| Fackeldey, A | 1 |
| Bachmann, R | 2 |
| Mühlhäuser, J | 1 |
| Träber, F | 1 |
| Oksendal, A | 1 |
| Pfeifer, U | 2 |
| Schild, HH | 1 |
| Schild, H | 1 |
| Kobayashi, N | 1 |
| Ito, M | 2 |
| Nakamura, J | 1 |
| Cai, J | 1 |
| Cao, C | 1 |
| Hammel, JM | 1 |
| Fox, IJ | 1 |
| Pohl, JF | 1 |
| Melin-Aldana, H | 1 |
| Sabla, G | 1 |
| Degen, JL | 1 |
| Bezerra, JA | 1 |
| Tahashi, Y | 1 |
| Matsuzaki, K | 1 |
| Date, M | 1 |
| Yoshida, K | 1 |
| Furukawa, F | 1 |
| Sugano, Y | 1 |
| Matsushita, M | 1 |
| Himeno, Y | 1 |
| Inagaki, Y | 1 |
| Inoue, K | 1 |
| Schaffner, F | 1 |
| Cikrt, M | 1 |
| Tichý, M | 1 |
| Holusa, R | 1 |
| Arakawa, Y | 1 |
| Suzuki, K | 1 |
| Takeuchi, S | 1 |
| Liu, P | 1 |
| Kawada, N | 1 |
| Mizoguchi, Y | 1 |
| Morisawa, S | 1 |
| Ogawa, M | 1 |
| Mori, T | 2 |
| Mori, Y | 1 |
| Ueda, S | 1 |
| Azemoto, R | 1 |
| Makino, Y | 1 |
| Wakashin, Y | 1 |
| Ohto, M | 1 |
| Wakashin, M | 1 |
| Yoshida, H | 1 |
| Yoshitake, I | 1 |
| Ohishi, E | 1 |
| Sano, J | 1 |
| Kubo, K | 1 |
| Mullen, KD | 1 |
| McCullough, AJ | 1 |
| Lamka, J | 1 |
| Kolárová, H | 1 |
| Maresová, J | 1 |
| Kvĕtina, J | 1 |
| Lie, TS | 1 |
| Nakajima, Y | 1 |
| Höfer, M | 1 |
| Lee, KS | 1 |
| Otani, Y | 1 |
| Nakano, H | 1 |
| Yahuaca, P | 1 |
| Amaya, A | 1 |
| Rojkind, M | 1 |
| Mourelle, M | 1 |
| Dumont, JM | 1 |
| Maignan, MF | 1 |
| Janin, B | 1 |
| Herbage, D | 1 |
| Perrissoud, D | 1 |
| Matsumoto, H | 1 |
| Kikuchi, S | 1 |
| Yachi, A | 1 |
| Yuasa, S | 1 |
| Sudoh, A | 1 |
| Toshida, K | 1 |
| Takechi, M | 1 |
| Umezu, K | 1 |
| Werin, WK | 1 |
| Karbowski, A | 1 |
| Skalba, P | 1 |
| Roschlau, G | 1 |
| Pal'tsyn, AA | 1 |
| Schmidt, E | 1 |
| Schmidt, FW | 1 |
| Uhlig, K | 1 |
| Kranz, D | 1 |
| Schneider, G | 1 |
| Strassburg, G | 1 |
| Toft, J | 1 |
| Yoshino, T | 1 |
| Owczarek, L | 1 |
4 reviews available for carbon tetrachloride and Chronic Disease
| Article | Year |
|---|---|
Role of hemostatic factors in hepatic injury and disease: animal models de-liver.
Topics: Animals; Bile Ducts; Blood Coagulation; Blood Coagulation Disorders; Carbon Tetrachloride; Chemical | 2016 |
The dangers from limited exposure to carbon tetrachloride.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chronic Disease; Drug | 1980 |
Hepatic drug metabolism and adverse hepatic drug reactions.
Topics: Adaptation, Biological; Animals; Biotransformation; Carbon Tetrachloride; Carbon Tetrachloride Poiso | 1975 |
[Immunopathology of chronic hepatitis and results of therapy with cytostatics].
Topics: Animals; Autoantibodies; Azathioprine; Carbon Tetrachloride; Cell Membrane Permeability; Cell Nucleu | 1969 |
80 other studies available for carbon tetrachloride and Chronic Disease
| Article | Year |
|---|---|
Neutrophil Chemotaxis and NETosis in Murine Chronic Liver Injury via Cannabinoid Receptor 1/ Gα
Topics: Animals; Cannabinoid Receptor Agonists; Carbon Tetrachloride; Chemotaxis; Chronic Disease; Cytoskele | 2020 |
Tetramethylpyrazine ameliorates hepatic fibrosis through autophagy-mediated inflammation.
Topics: Animals; Autophagy; Carbon Tetrachloride; Cell Line, Tumor; Chromones; Chronic Disease; Fibrinolytic | 2020 |
Smad3 gene C-terminal phosphorylation site mutation aggravates CCl
Topics: Acute Disease; Animals; Body Weight; Breeding; Carbon Tetrachloride; Chronic Disease; Embryo, Mammal | 2020 |
MiR-126 Regulates Properties of SOX9
Topics: Animals; Base Sequence; Carbon Tetrachloride; Cell Differentiation; Cell Line, Tumor; Cell Prolifera | 2020 |
Perivenous Stellate Cells Are the Main Source of Myofibroblasts and Cancer-Associated Fibroblasts Formed After Chronic Liver Injuries.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Bile Ducts; Cancer-Associated Fibroblasts; Ca | 2021 |
Placental growth factor silencing ameliorates liver fibrosis and angiogenesis and inhibits activation of hepatic stellate cells in a murine model of chronic liver disease.
Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Chronic Disease; Disease Models, | 2017 |
Gallic Acid and Dodecyl Gallate Prevents Carbon Tetrachloride-Induced Acute and Chronic Hepatotoxicity by Enhancing Hepatic Antioxidant Status and Increasing p53 Expression.
Topics: Acute Disease; Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; | 2017 |
GDF15 deficiency exacerbates chronic alcohol- and carbon tetrachloride-induced liver injury.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chronic Disease; Cytokines; E | 2017 |
Reactive cholangiocytes differentiate into proliferative hepatocytes with efficient DNA repair in mice with chronic liver injury.
Topics: Animals; Bile Ducts; Carbon Tetrachloride; Cell Differentiation; Cell Proliferation; Chemical and Dr | 2019 |
TAFI deficiency promotes liver damage in murine models of liver failure through defective down-regulation of hepatic inflammation.
Topics: Acetaminophen; Actins; Acute Disease; Alanine Transaminase; Animals; Aspartate Aminotransferases; Ca | 2013 |
Wu-Chia-Pi solution attenuates carbon tetrachloride-induced hepatic injury through the antioxidative abilities of its components acteoside and quercetin.
Topics: Administration, Oral; Animals; Antioxidants; Carbon Tetrachloride; Catalase; Chemical and Drug Induc | 2012 |
Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis.
Topics: Acute Disease; Animals; Bile Ducts; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury, Ch | 2014 |
Toll-like receptor 7-mediated type I interferon signaling prevents cholestasis- and hepatotoxin-induced liver fibrosis.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cholestasis; Chronic Disease; | 2014 |
Protective effects of Ephedra pachyclada extract on mouse models of carbon tetrachloride- induced chronic and acute liver failure.
Topics: Acute Disease; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Che | 2014 |
Transforming growth factor-β-independent role of connective tissue growth factor in the development of liver fibrosis.
Topics: Animals; Carbon Tetrachloride; Chronic Disease; Collagen Type I; Connective Tissue Growth Factor; Di | 2014 |
Gas6/Axl pathway is activated in chronic liver disease and its targeting reduces fibrosis via hepatic stellate cell inactivation.
Topics: Adult; Aged; Animals; c-Mer Tyrosine Kinase; Carbon Tetrachloride; Cell Proliferation; Cells, Cultur | 2015 |
Hepatitis C Virus Nonstructural 3/4A Protein Dampens Inflammation and Contributes to Slow Fibrosis Progression during Chronic Fibrosis In Vivo.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Carrier Proteins; Cell Proliferation; Chronic Disease; | 2015 |
CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism.
Topics: Actins; Angiogenesis Inducing Agents; Animals; Antigens, CD; Antigens, Neoplasm; Becaplermin; Carbon | 2016 |
Ubiquitin C-terminal hydrolase 1: A novel functional marker for liver myofibroblasts and a therapeutic target in chronic liver disease.
Topics: Animals; Biomarkers; Carbon Tetrachloride; Cell Proliferation; Cell Transdifferentiation; Cells, Cul | 2015 |
Molecular Mechanism Responsible for Fibronectin-controlled Alterations in Matrix Stiffness in Advanced Chronic Liver Fibrogenesis.
Topics: Animals; Biological Availability; Carbon Tetrachloride; Chronic Disease; Collagen; Extracellular Mat | 2016 |
Mesenchymal stem cells and their secreted molecules predominantly ameliorate fulminant hepatic failure and chronic liver fibrosis in mice respectively.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Cell Proliferation; Chronic Disease; Culture Media, Condit | 2016 |
MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression.
Topics: Animals; Base Sequence; Carbon Tetrachloride; Carcinoma, Hepatocellular; Choline; Chronic Disease; D | 2016 |
[Preventive and treatment effects of granulocyte colony stimulating factor on CCl4 induced chronic liver injury in mice].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury, Chronic; Chronic Disease; Gra | 2008 |
[Morphometry of hepatocyte mitochondrial apparatus in normal and cirrhotic rat liver].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chronic Disease; H | 2008 |
Control of acute, chronic, and constitutive hyperammonemia by wild-type and genetically engineered Lactobacillus plantarum in rodents.
Topics: Acute Disease; Alanine; Ammonia; Animals; Carbon Tetrachloride; Chronic Disease; Disease Models, Ani | 2008 |
Protective effects of emodin and astragalus polysaccharides on chronic hepatic injury in rats.
Topics: Alanine Transaminase; Animals; Astragalus Plant; Carbon Tetrachloride; Chronic Disease; Emodin; Live | 2008 |
Synergistic hepatoprotective effect of Schisandrae lignans with Astragalus polysaccharides on chronic liver injury in rats.
Topics: Animals; Astragalus propinquus; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chroni | 2009 |
Striking LD50 variation associated with fluctuations of CYP2E1-positive cells in hepatic lobule during chronic CCl4 exposure in mice.
Topics: Acute Disease; Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Carbon Tetrach | 2010 |
Snail1 transcription factor is a critical mediator of hepatic stellate cell activation following hepatic injury.
Topics: Acute Disease; Adult; Aged; Animals; Blotting, Western; Carbon Tetrachloride; Cell Transdifferentiat | 2011 |
Effects of acetyl salycilic acid and ibuprofen in chronic liver damage induced by CCl4.
Topics: Animals; Aspirin; Blotting, Western; Carbon Tetrachloride; Cell Nucleus; Chronic Disease; Collagen; | 2012 |
Hydroxysafflor yellow A protects against chronic carbon tetrachloride-induced liver fibrosis.
Topics: Animals; Carbon Tetrachloride; Chalcone; Chronic Disease; Collagen Type I; Gene Expression Regulatio | 2011 |
Increased susceptibility to liver fibrosis with age is correlated with an altered inflammatory response.
Topics: Aging; Animals; Carbon Tetrachloride; Cell Proliferation; Chronic Disease; Disease Susceptibility; H | 2011 |
Protective effects of allopurinol against acute liver damage and cirrhosis induced by carbon tetrachloride: modulation of NF-κB, cytokine production and oxidative stress.
Topics: Alanine Transaminase; Allopurinol; Animals; Blotting, Western; Carbon Tetrachloride; Cell Extracts; | 2012 |
Snailase preparation of ginsenoside M1 from protopanaxadiol-type ginsenoside and their protective effects against CCl4-induced chronic hepatotoxicity in mice.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biotransformation; Body We | 2011 |
Antifibrotic effects of Artemisia capillaris and Artemisia iwayomogi in a carbon tetrachloride-induced chronic hepatic fibrosis animal model.
Topics: Alkaline Phosphatase; Animals; Antioxidants; Artemisia; Carbon Tetrachloride; Chemical and Drug Indu | 2012 |
Phenacetin O-deethylation is a useful tool for evaluation of hepatic functional reserve in rats with CCl(4)-induced chronic liver injury.
Topics: Animals; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chronic Disease; | 2012 |
Hepatic miR-29ab1 expression modulates chronic hepatic injury.
Topics: Animals; Carbon Tetrachloride; Chronic Disease; Gene Expression Profiling; Gene Expression Regulatio | 2012 |
Supplementation with branched-chain amino acids attenuates hepatic apoptosis in rats with chronic liver disease.
Topics: Amino Acids, Branched-Chain; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Carb | 2012 |
Leptin is essential for the hepatic fibrogenic response to chronic liver injury.
Topics: Animals; Carbon Tetrachloride; Chronic Disease; Disease Progression; Fatty Liver; Female; Leptin; Li | 2002 |
[Green tea extracts protected against carbon tetrachloride-induced chronic liver damage and cirrhosis].
Topics: Animals; Carbon Tetrachloride; Chronic Disease; Liver; Liver Cirrhosis; Male; Malondialdehyde; Plant | 2002 |
Inhibitive effect of cordyceps sinensis on experimental hepatic fibrosis and its possible mechanism.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chronic Disease; Cordyceps; D | 2003 |
Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases.
Topics: Acute Disease; Adolescent; Adult; Aged; Animals; Antigens, CD; Carbon Tetrachloride; Cell Division; | 2003 |
[Liver damage as a sequel to chronic industrial poisoning with carbon hydrochloride].
Topics: Carbon; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chronic Disease; Humans; Liver Disease | 1955 |
[Effects of vitamin B-12 alone and associated with folic acid, vitamin C and vitamin PP on hepatic lesions and on humoral behavior in the course of chronic poisoning with carbon tetrachloride. Experimental research].
Topics: Ascorbic Acid; Carbon Tetrachloride; Chronic Disease; Folic Acid; Humans; Liver Diseases; Niacinamid | 1961 |
Effects of liver failure on branched-chain alpha-keto acid dehydrogenase complex in rat liver and muscle: comparison between acute and chronic liver failure.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Branched-Chain; Animals; Carbon Tetr | 2004 |
Immunohistochemical distribution of activated nuclear factor kappaB and peroxisome proliferator-activated receptors in carbon tetrachloride-induced chronic liver injury in rats.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chronic Disease; Hepatocytes; | 2005 |
Inhibition of 5-lipoxygenase-activating protein abrogates experimental liver injury: role of Kupffer cells.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Arachidonate 5-Lipoxygenase; Carbon Tetrachloride; Carr | 2005 |
Cryopreserved fetal liver cell transplants support the chronic failing liver in rats with CCl4-induced cirrhosis.
Topics: Animals; Carbon Tetrachloride; Chronic Disease; Cryopreservation; Cytochrome P-450 Enzyme System; Di | 2006 |
Development of dosage design of hepatic metabolizing drugs using serum albumin level in chronic hepatic failure.
Topics: Animals; Carbon Tetrachloride; Chronic Disease; Liver; Liver Failure; Male; Protein Binding; Rats; R | 2006 |
Influence of chronic hepatic failure on disposition kinetics of valproate excretion through a phase II reaction in rats treated with carbon tetrachloride.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Anticonvulsants; Area Under Curve; Aspartate Am | 2007 |
Fucoidan partly prevents CCl4-induced liver fibrosis.
Topics: Acute Disease; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cel | 2008 |
Endothelial nitric oxide synthase is a critical factor in experimental liver fibrosis.
Topics: Alanine Transaminase; Animals; Arginine; Blotting, Western; Carbon Tetrachloride; Chronic Disease; D | 2008 |
Kupffer cell function in chronic liver injury and after partial hepatectomy.
Topics: Animals; Carbon Tetrachloride; Chronic Disease; Hepatectomy; Kupffer Cells; Liver; Liver Cirrhosis, | 1994 |
Dynamics of hepatic collagen synthesis and intracellular degradation of newly synthesized collagen during chronic carbon tetrachloride-induced liver injury in rats.
Topics: Animals; Carbon Tetrachloride; Chronic Disease; Collagen; Liver; Liver Cirrhosis, Experimental; Male | 1994 |
Active oxygen species in the liver of rats submitted to chronic hypobaric hypoxia.
Topics: Altitude; Animals; Carbon Tetrachloride; Chronic Disease; Female; Homeostasis; Hydrogen Peroxide; Hy | 1993 |
Prolonged decrease in hepatic connexin32 in chronic liver injury induced by carbon tetrachloride in rats.
Topics: Alanine Transaminase; Animals; Blotting, Northern; Carbon Tetrachloride; Cell Division; Chemical and | 1996 |
Diagnostic value of a superparamagnetic iron oxide in MR imaging of chronic liver disease in an animal model.
Topics: Animals; Carbon Tetrachloride; Chronic Disease; Contrast Media; Ferric Compounds; Liver; Liver Cirrh | 1998 |
Evaluation of different models of experimentally induced liver cirrhosis for MRI research with correlation to histopathologic findings.
Topics: Animals; Carbon Tetrachloride; Carcinogens; Chronic Disease; Follow-Up Studies; Liver; Liver Cirrhos | 1999 |
The role of hepatocyte transplantation to treat chronic liver failure.
Topics: Ammonia; Animals; Bilirubin; Carbon Tetrachloride; Cell Transplantation; Chronic Disease; Hepatocyte | 2000 |
Plasminogen deficiency leads to impaired lobular reorganization and matrix accumulation after chronic liver injury.
Topics: Afibrinogenemia; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chronic Dise | 2001 |
Differential regulation of TGF-beta signal in hepatic stellate cells between acute and chronic rat liver injury.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Cell Division; Cell Line; Cells, Cultured; Chemical an | 2002 |
Biliary excretion of 64Cu, 65Zn and 203Hg in the rat with liver injury induced by CCl4.
Topics: Animals; Bile; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chronic Disease; Copper; Female | 1975 |
Zinc status in liver and gastrointestinal diseases.
Topics: Adult; Animals; Carbon Tetrachloride; Carrier Proteins; Chronic Disease; Copper; Gastrointestinal Di | 1992 |
Arachidonate metabolism in D-galactosamine or carbon tetrachloride-induced acute and chronic liver injuries in rats.
Topics: Acute Disease; Animals; Arachidonic Acids; Carbon Tetrachloride; Chemical and Drug Induced Liver Inj | 1992 |
Study on chronic renal injuries induced by carbon tetrachloride: selective inhibition of the nephrotoxicity by irradiation.
Topics: Animals; Blood Urea Nitrogen; Carbon Tetrachloride; Chronic Disease; Fluorescent Antibody Technique; | 1992 |
Effects of KF-14363 on liver fibrosis in rats with chronic liver injury induced by carbon tetrachloride.
Topics: Alkaline Phosphatase; Animals; Benzazepines; Carbon Tetrachloride; Chronic Disease; Hydroxyproline; | 1991 |
Problems with animal models of chronic liver disease: suggestions for improvement in standardization.
Topics: Animals; Behavior, Animal; Carbon Tetrachloride; Chronic Disease; Disease Models, Animal; Hepatic En | 1989 |
The influence of experimentally induced pathological states on the flow and composition of central lymph in the rat.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Chronic Disease; Fasting; Female; Kidney Diseases; Liv | 1986 |
Alteration of thymus and of immune regulatory-antifibroblast factors in acute and chronic hepatic damage.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Cell Count; Cell Division; Chronic Disease; Dimethylni | 1987 |
Cryptic adenosine triphosphatase activities in plasma membranes of CCl4-cirrhotic rats. Its modulation by changes in cholesterol/phospholipid ratios.
Topics: Acute Disease; Animals; Calcium-Transporting ATPases; Carbon Tetrachloride; Carbon Tetrachloride Poi | 1985 |
Effect of malotilate on chronic liver injury induced by carbon tetrachloride in the rat.
Topics: Animals; Body Weight; Carbon Tetrachloride; Chronic Disease; Collagen; Liver; Liver Cirrhosis, Exper | 1986 |
[A comparative study of free amino acid levels in the serum and cerebral cortex in hepatic failure rats].
Topics: Acute Disease; Amino Acids; Ammonia; Animals; Blood-Brain Barrier; Carbon Tetrachloride; Cerebral Co | 1986 |
[Therapeutic effect of TRQ on chronic liver injury model in rats induced by CCl4].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Carbon Tetrachloride; Chemi | 1985 |
[Changes in the bile secretion and bile ductules in the course of development of experimental hepatitis and liver cirrhosis].
Topics: Acute Disease; Adenosine Triphosphatases; Animals; Bile; Bile Ducts; Carbon Tetrachloride; Chemical | 1971 |
Some renal histochemical lesions in rats chronically poisoned with carbon tetrachloride.
Topics: Alkaline Phosphatase; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chronic Disease | 1968 |
[Possibilities of protraction of murine viral hepatitis. An experimental study].
Topics: Amyloidosis; Animals; Carbon Tetrachloride; Chronic Disease; Female; Freund's Adjuvant; Hepatitis, A | 1972 |
[An autoradiographic study of DNA and RNA synthesis in the liver cells of mice with chronic carbon tetrachloride poisoning].
Topics: Animals; Autoradiography; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug In | 1973 |
[Comparative studies on the induction of chronic hepatitis in the rat].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chronic Disease; Diabetes Mel | 1971 |
The clinical and experimental studies on the metabolism of folic acid using tritiated folic acid. 3. Plasma clearance in man and organ distribution in rat following intravenous administration of tritiated folic acid.
Topics: Acute Disease; Animals; Body Weight; Bone Marrow; Carbon Tetrachloride; Chronic Disease; Folic Acid; | 1968 |
[Zn 65 uptake in the cirrhotic liver of rats treated with carbon tetrachloride].
Topics: Animals; Carbon Tetrachloride; Chronic Disease; Kidney; Liver; Liver Cirrhosis, Experimental; Rats; | 1968 |