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carbon tetrachloride and Choline Deficiency

carbon tetrachloride has been researched along with Choline Deficiency in 11 studies

Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.

Choline Deficiency: A condition produced by a deficiency of CHOLINE in animals. Choline is known as a lipotropic agent because it has been shown to promote the transport of excess fat from the liver under certain conditions in laboratory animals. Combined deficiency of choline (included in the B vitamin complex) and all other methyl group donors causes liver cirrhosis in some animals. Unlike compounds normally considered as vitamins, choline does not serve as a cofactor in enzymatic reactions. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)

Research Excerpts

ExcerptRelevanceReference
"CCl4 produced hepatocellular necrosis."5.29Effects of alcohol, carbon tetrachloride, and choline deficiency on iron metabolism in the rat. ( Batey, RG; Johnston, R, 1993)
" Carbon tetrachloride and methionine/choline deficiency were used as chronic liver injury models."3.77Liver X receptor signaling is a determinant of stellate cell activation and susceptibility to fibrotic liver disease. ( Beaven, SW; Bensinger, S; Hong, C; Tontonoz, P; Tsukamoto, H; Wang, J; Wroblewski, K, 2011)
" In the present study, we address the role of Gas6 in steatohepatitis and progression to liver fibrosis using Gas6-deficient mice fed a choline-deficient ethionine-supplemented diet (CDE) or receiving a chronic carbon tetrachloride (CCl(4)) treatment."3.77Gas6 deficiency prevents liver inflammation, steatohepatitis, and fibrosis in mice. ( Brouillet, A; Chobert, MN; Couchie, D; Fourcot, A; Laperche, Y; Mavier, P; Zafrani, ES, 2011)
"Here, we use experimental models of liver fibrosis to show that deficiency of the scavenger receptor, stabilin-1, exacerbates fibrosis and delays resolution during the recovery phase."1.43Stabilin-1 expression defines a subset of macrophages that mediate tissue homeostasis and prevent fibrosis in chronic liver injury. ( Adams, DH; Dawes, H; Elima, K; Gerke, H; Hübscher, SG; Jalkanen, S; Karikoski, M; Laurila, J; Ohlmeier, S; Patten, DA; Rantakari, P; Salmi, M; Shetty, S; Valtonen, J; Weston, CJ, 2016)
"In rats with steatohepatitis, mean elasticity (2."1.35Early detection of steatohepatitis in fatty rat liver by using MR elastography. ( Abarca-Quinones, J; Dorvillius, M; Fink, M; Larrat, B; Leclercq, I; Pallu, S; Salameh, N; Sinkus, R; Van Beers, BE, 2009)
"CCl4 produced hepatocellular necrosis."1.29Effects of alcohol, carbon tetrachloride, and choline deficiency on iron metabolism in the rat. ( Batey, RG; Johnston, R, 1993)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's1 (9.09)18.2507
2000's1 (9.09)29.6817
2010's5 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rantakari, P1
Patten, DA1
Valtonen, J1
Karikoski, M1
Gerke, H1
Dawes, H1
Laurila, J1
Ohlmeier, S1
Elima, K1
Hübscher, SG1
Weston, CJ1
Jalkanen, S1
Adams, DH1
Salmi, M1
Shetty, S1
Salameh, N1
Larrat, B1
Abarca-Quinones, J1
Pallu, S1
Dorvillius, M1
Leclercq, I1
Fink, M1
Sinkus, R1
Van Beers, BE1
Kallis, YN1
Robson, AJ1
Fallowfield, JA1
Thomas, HC1
Alison, MR1
Wright, NA1
Goldin, RD1
Iredale, JP1
Forbes, SJ1
Beaven, SW1
Wroblewski, K1
Wang, J1
Hong, C1
Bensinger, S1
Tsukamoto, H1
Tontonoz, P1
Fourcot, A1
Couchie, D1
Chobert, MN1
Zafrani, ES1
Mavier, P1
Laperche, Y1
Brouillet, A1
Español-Suñer, R1
Carpentier, R1
Van Hul, N1
Legry, V1
Achouri, Y1
Cordi, S1
Jacquemin, P1
Lemaigre, F1
Leclercq, IA1
HARTMANN, F1
HESS, RG1
Powell, LW1
Batey, RG1
Johnston, R1
Wilson, ER1
Williams, WL1
Miller, JE1
Cornatzer, WE1

Other Studies

11 other studies available for carbon tetrachloride and Choline Deficiency

ArticleYear
Stabilin-1 expression defines a subset of macrophages that mediate tissue homeostasis and prevent fibrosis in chronic liver injury.
    Proceedings of the National Academy of Sciences of the United States of America, 2016, 08-16, Volume: 113, Issue:33

    Topics: Animals; Carbon Tetrachloride; Cell Adhesion Molecules, Neuronal; Chemical and Drug Induced Liver In

2016
Early detection of steatohepatitis in fatty rat liver by using MR elastography.
    Radiology, 2009, Volume: 253, Issue:1

    Topics: Animals; Carbon Tetrachloride; Choline Deficiency; Elasticity Imaging Techniques; Fatty Liver; Male;

2009
Remodelling of extracellular matrix is a requirement for the hepatic progenitor cell response.
    Gut, 2011, Volume: 60, Issue:4

    Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Carbon Tetrachloride; Choline Deficiency; C

2011
Liver X receptor signaling is a determinant of stellate cell activation and susceptibility to fibrotic liver disease.
    Gastroenterology, 2011, Volume: 140, Issue:3

    Topics: Animals; Biomarkers; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver Injury;

2011
Gas6 deficiency prevents liver inflammation, steatohepatitis, and fibrosis in mice.
    American journal of physiology. Gastrointestinal and liver physiology, 2011, Volume: 300, Issue:6

    Topics: Animals; Axl Receptor Tyrosine Kinase; Carbon Tetrachloride; Cell Proliferation; Choline Deficiency;

2011
Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice.
    Gastroenterology, 2012, Volume: 143, Issue:6

    Topics: Animals; Carbon Tetrachloride; Cell Differentiation; Chemical and Drug Induced Liver Injury; Choline

2012
[Importance of lecithin in fat metabolism & experimental fatty liver in rat].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1958, Volume: 18, Issue:4

    Topics: Animals; Carbon Tetrachloride; Choline; Choline Deficiency; Fatty Liver; Lecithins; Lipid Metabolism

1958
The effect of cirrhosis and ethanol ingestion on hepatic iron deposition in the rat.
    The Journal of pathology and bacteriology, 1967, Volume: 93, Issue:1

    Topics: Animals; Carbon Tetrachloride; Choline Deficiency; Ethanol; Iron; Liver; Liver Cirrhosis, Experiment

1967
Effects of alcohol, carbon tetrachloride, and choline deficiency on iron metabolism in the rat.
    Alcoholism, clinical and experimental research, 1993, Volume: 17, Issue:5

    Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Choline Deficiency; Ethanol;

1993
Responses of fatty livers of mice of carbon tetrachloride.
    The Anatomical record, 1969, Volume: 165, Issue:3

    Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Choline; Choline Deficiency; Dietary

1969
Studies on liver phosphatidyl cholines: I. Effects of fatty liver induction on phosphatidyl cholines from liver mitochondria and microsomes.
    Lipids, 1969, Volume: 4, Issue:1

    Topics: Animals; Body Weight; Carbon Tetrachloride; Choline Deficiency; Chromatography, Gas; Chromatography,

1969