carbon tetrachloride has been researched along with Cell Transformation, Neoplastic in 22 studies
Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin is a hypoglycaemic agent used to treat type 2 diabetes mellitus (DM2) patients, with a broad safety profile." | 5.51 | Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepatocellular carcinoma. ( Callegari, E; Gramantieri, L; Guerriero, P; Negrini, M; Pinton, P; Rimessi, A; Sabbioni, S; Shankaraiah, RC; Silini, EM, 2019) |
| "Metformin is a hypoglycaemic agent used to treat type 2 diabetes mellitus (DM2) patients, with a broad safety profile." | 1.51 | Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepatocellular carcinoma. ( Callegari, E; Gramantieri, L; Guerriero, P; Negrini, M; Pinton, P; Rimessi, A; Sabbioni, S; Shankaraiah, RC; Silini, EM, 2019) |
| "A mouse model of fibrosis-associated liver cancer that was designed to emulate cirrhotic liver, a prevailing disease state observed in most humans with HCC, was used." | 1.40 | Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice. ( Beland, FA; Chappell, G; Hoenerhoff, M; Hong, HH; Kutanzi, K; Pogribny, IP; Rusyn, I; Tryndyak, V; Uehara, T, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (31.82) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 11 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shankaraiah, RC | 1 |
| Callegari, E | 1 |
| Guerriero, P | 1 |
| Rimessi, A | 1 |
| Pinton, P | 1 |
| Gramantieri, L | 1 |
| Silini, EM | 1 |
| Sabbioni, S | 1 |
| Negrini, M | 1 |
| Wang, P | 1 |
| Cong, M | 1 |
| Liu, T | 1 |
| Xu, H | 1 |
| Wang, L | 1 |
| Sun, G | 1 |
| Yang, A | 1 |
| Zhang, D | 1 |
| Huang, J | 1 |
| Sun, Y | 2 |
| Zhao, W | 1 |
| Ma, H | 1 |
| Jia, J | 1 |
| You, H | 1 |
| Dou, C | 1 |
| Liu, Z | 1 |
| Tu, K | 1 |
| Zhang, H | 1 |
| Chen, C | 1 |
| Yaqoob, U | 1 |
| Wang, Y | 1 |
| Wen, J | 1 |
| van Deursen, J | 1 |
| Sicard, D | 1 |
| Tschumperlin, D | 1 |
| Zou, H | 1 |
| Huang, WC | 1 |
| Urrutia, R | 1 |
| Shah, VH | 1 |
| Kang, N | 1 |
| Ito, Y | 1 |
| Nakajima, K | 1 |
| Masubuchi, Y | 1 |
| Kikuchi, S | 1 |
| Saito, F | 1 |
| Akahori, Y | 1 |
| Jin, M | 1 |
| Yoshida, T | 1 |
| Shibutani, M | 1 |
| Papp, V | 1 |
| Rókusz, A | 1 |
| Dezső, K | 1 |
| Bugyik, E | 1 |
| Szabó, V | 1 |
| Pávai, Z | 1 |
| Paku, S | 1 |
| Nagy, P | 1 |
| Chappell, G | 1 |
| Kutanzi, K | 2 |
| Uehara, T | 2 |
| Tryndyak, V | 1 |
| Hong, HH | 1 |
| Hoenerhoff, M | 1 |
| Beland, FA | 1 |
| Rusyn, I | 2 |
| Pogribny, IP | 2 |
| Caviglia, JM | 1 |
| Schwabe, RF | 2 |
| Xue, F | 1 |
| Hu, L | 1 |
| Ge, R | 1 |
| Yang, L | 1 |
| Liu, K | 1 |
| Li, Y | 1 |
| Wang, K | 1 |
| Kluwe, J | 1 |
| Wongsiriroj, N | 1 |
| Troeger, JS | 1 |
| Gwak, GY | 1 |
| Dapito, DH | 1 |
| Pradere, JP | 1 |
| Jiang, H | 1 |
| Siddiqi, M | 1 |
| Piantedosi, R | 1 |
| O'Byrne, SM | 1 |
| Blaner, WS | 1 |
| Maeda, M | 1 |
| Takami, T | 1 |
| Terai, S | 1 |
| Sakaida, I | 1 |
| Ainslie, GR | 1 |
| Muskhelishvili, L | 1 |
| Izawa, T | 1 |
| Yamate, J | 1 |
| Kosyk, O | 1 |
| Shymonyak, S | 1 |
| Bradford, BU | 1 |
| Boorman, GA | 1 |
| Bataller, R | 1 |
| Xu, XB | 1 |
| Leng, XS | 1 |
| Yang, X | 1 |
| He, ZP | 1 |
| Aziz, TA | 1 |
| Aziz, MA | 1 |
| Fouad, HH | 1 |
| Rashed, LA | 1 |
| Salama, H | 1 |
| Abd-Alla, S | 1 |
| Wehab, MA | 1 |
| Ahmed, T | 1 |
| Huang, X | 1 |
| Yu, C | 1 |
| Jin, C | 1 |
| Yang, C | 1 |
| Xie, R | 1 |
| Cao, D | 1 |
| Wang, F | 1 |
| McKeehan, WL | 1 |
| Ehlvest, J | 1 |
| Veidebaum, T | 1 |
| Põldvere, E | 1 |
| Faktor, VM | 1 |
| Poltoranina, VS | 1 |
| Uryvaeva, IV | 1 |
| Qin, G | 1 |
| Ning, Y | 1 |
| Lotlikar, PD | 1 |
| Farber, E | 1 |
| Parker, S | 1 |
| Gruenstein, M | 1 |
| Deleener, A | 1 |
| de Gerlache, J | 1 |
| Lans, M | 1 |
| Kirsch-Volders, M | 1 |
| Saliamon, LS | 1 |
| Ashmarin, IP | 1 |
| Ostretsova, IB | 1 |
| Lyzlova, SN | 1 |
| Pluzhnikova, GF | 1 |
| Vas'kina, LV | 1 |
| Dzhioev, FK | 1 |
| Balanski, RM | 1 |
| Grigorovich, NA | 1 |
| Balagovskaia, ZhM | 1 |
22 other studies available for carbon tetrachloride and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepatocellular carcinoma.
Topics: Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Disease M | 2019 |
Inhibitory effects of HNF4α on migration/maltransformation of hepatic progenitors: HNF4α-overexpressing hepatic progenitors for liver repopulation.
Topics: Animals; Carbon Tetrachloride; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; G | 2017 |
P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts.
Topics: Animals; Benzoates; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Nucleus; Cell Transdiffere | 2018 |
Expression Characteristics of Genes Hypermethylated and Downregulated in Rat Liver Specific to Nongenotoxic Hepatocarcinogens.
Topics: Animals; Cadherins; Carbon Tetrachloride; Cell Proliferation; Cell Transformation, Neoplastic; Dieth | 2019 |
Expansion of hepatic stem cell compartment boosts liver regeneration.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Different | 2014 |
Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice.
Topics: Animals; beta Catenin; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Transformation, Neoplas | 2014 |
Mouse models of liver cancer.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; | 2015 |
Autophagy-deficiency in hepatic progenitor cells leads to the defects of stemness and enhances susceptibility to neoplastic transformation.
Topics: Animals; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Carbon Tetrachloride; | 2016 |
Absence of hepatic stellate cell retinoid lipid droplets does not enhance hepatic fibrosis but decreases hepatic carcinogenesis.
Topics: Acyltransferases; Animals; Carbon Tetrachloride; Cell Transformation, Neoplastic; Cells, Cultured; D | 2011 |
Autologous bone marrow cell infusions suppress tumor initiation in hepatocarcinogenic mice with liver cirrhosis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Bone Marrow Transplantation; Carbon Tetrachloride; Carcinoma, | 2012 |
Molecular mechanisms of fibrosis-associated promotion of liver carcinogenesis.
Topics: Animals; Animals, Newborn; Carbon Tetrachloride; Cell Transformation, Neoplastic; Diethylnitrosamine | 2013 |
[Obstruction of TGF-beta1 signal transduction can decrease the process of hepatocellular carcinoma in mice induced by CCl4/ethanol].
Topics: Adenoviridae; Animals; Antisense Elements (Genetics); Carbon Tetrachloride; Cell Transformation, Neo | 2004 |
Interferon-alpha gene therapy prevents aflatoxin and carbon tetrachloride promoted hepatic carcinogenesis in rats.
Topics: Aflatoxins; Animals; Carbon Tetrachloride; Cell Line; Cell Transformation, Neoplastic; Disease Model | 2005 |
Forced expression of hepatocyte-specific fibroblast growth factor 21 delays initiation of chemically induced hepatocarcinogenesis.
Topics: Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Fibroblas | 2006 |
Role of mitotic activity in target tissues in N-nitrosodiethylamine carcinogenesis.
Topics: Animals; Carbon Tetrachloride; Cell Division; Cell Transformation, Neoplastic; Dexamethasone; Diethy | 1983 |
[Changes in the nature of the hepatocyte proliferation in the liver and adenomatous nodes of mice in CC14-induced carcinogenesis].
Topics: Animals; Carbon Tetrachloride; Cell Transformation, Neoplastic; DNA, Neoplasm; Liver; Liver Neoplasm | 1982 |
Chemoprevention of aflatoxin B1-initiated and carbon tetrachloride-promoted hepatocarcinogenesis in the rat by green tea.
Topics: Aflatoxin B1; Animals; Carbon Tetrachloride; Cell Division; Cell Transformation, Neoplastic; Fibrosi | 2000 |
The resistance of putative premalignant liver cell populations, hyperplastic nodules, to the acute cytotoxic effects of some hepatocarcinogens.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinogens; Cell Transformation, Neoplastic; | 1976 |
Nucleolar changes during the first steps of experimental hepatocarcinogenesis in rats.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Cell Nucleolus; Cell Transformation, Neoplasti | 1985 |
[Analysis of tumor transformation in tissues. II. Biochemical dedifferentiation in the process of cancerogenesis (changes in creatine kinase and alkaline phosphatase as an example)].
Topics: Alkaline Phosphatase; Animals; Anura; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Transfor | 1970 |
[Inhibition of urethane carcinogenesis by antioxidants and carbon tetrachloride].
Topics: Adenoma; Administration, Oral; Animals; Antioxidants; Carbon Tetrachloride; Cell Transformation, Neo | 1974 |
[Comparative study of the action of blastomogenic agents on the genetic apparatus of animal cells. I. Effect of different types of blastomogenic agents on the DNA nucleotide composition of cells sensitive to blastomogens].
Topics: Animals; Carbon Tetrachloride; Cell Transformation, Neoplastic; DNA; DNA, Neoplasm; Estradiol; Femal | 1970 |