carbon tetrachloride has been researched along with Bile Duct Obstruction in 32 studies
Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Curcumin attenuates liver injury induced by ethanol, thioacetamide, iron overdose, cholestasis and acute, subchronic and chronic carbon tetrachloride (CCl(4)) intoxication; moreover, it reverses CCl(4) cirrhosis to some extent." | 8.85 | Pharmacological actions of curcumin in liver diseases or damage. ( Muriel, P; Rivera-Espinoza, Y, 2009) |
| " Significant anticholestatic activity was also observed against carbon tetrachloride induced cholestasis in conscious rat, anaesthetized guinea pig and cat." | 7.68 | Anticholestatic effect of picroliv, active hepatoprotective principle of Picrorhiza kurrooa, against carbon tetrachloride induced cholestasis. ( Dhawan, BN; Patnaik, GK; Saraswat, B; Visen, PK, 1993) |
| "Curcumin is a phytophenolic compound, which is highly efficacious for treating several inflammatory diseases." | 5.35 | Curcumin prevents and reverses cirrhosis induced by bile duct obstruction or CCl4 in rats: role of TGF-beta modulation and oxidative stress. ( Moreno, MG; Muriel, P; Reyes-Gordillo, K; Segovia, J; Shibayama, M; Tsutsumi, V; Vergara, P, 2008) |
| "Administration of the non-metabolizable organic anion indocyanine green (ICG) prior to a toxic dose of acetaminophen (4-acetamidophenol; APAP) reduces liver injury 24h after dosing." | 5.33 | Cholestasis induced by model organic anions protects from acetaminophen hepatotoxicity in male CD-1 mice. ( Hennig, GE; Manautou, JE; Silva, VM, 2006) |
| " Curcumin attenuates liver injury induced by ethanol, thioacetamide, iron overdose, cholestasis and acute, subchronic and chronic carbon tetrachloride (CCl(4)) intoxication; moreover, it reverses CCl(4) cirrhosis to some extent." | 4.85 | Pharmacological actions of curcumin in liver diseases or damage. ( Muriel, P; Rivera-Espinoza, Y, 2009) |
| " To explore the role of MMP-2 in hepatic fibrogenesis, we employed two fibrosis models in mice; toxin (carbon tetrachloride, CCl4)-induced and cholestasis-induced fibrosis." | 3.77 | Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice. ( Funaoka, Y; Kakinuma, S; Kamiya, A; Kiyohashi, K; Koshikawa, N; Miyoshi, M; Nakagawa, M; Nakauchi, H; Onozuka, I; Sakamoto, N; Seiki, M; Ueyama, M; Watanabe, M; Watanabe, T, 2011) |
| " In this study, we describe a rat model of fatigue assessment using a swim tank, and we used this model to document the degree of fatigue in rat models of cholestasis caused by bile duct resection (BDR) and of hepatitis caused by carbon tetrachloride (CCl4) administration." | 3.69 | Improvement in cholestasis-associated fatigue with a serotonin receptor agonist using a novel rat model of fatigue assessment. ( Maric, M; Swain, MG, 1997) |
| " Significant anticholestatic activity was also observed against carbon tetrachloride induced cholestasis in conscious rat, anaesthetized guinea pig and cat." | 3.68 | Anticholestatic effect of picroliv, active hepatoprotective principle of Picrorhiza kurrooa, against carbon tetrachloride induced cholestasis. ( Dhawan, BN; Patnaik, GK; Saraswat, B; Visen, PK, 1993) |
| " Artificial-chylomicron delipidation and remnant disappearance from plasma were investigated in rats with carbon tetrachloride-induced hepatic cirrhosis or with cholestasis due to bile-duct ligation." | 3.68 | Chylomicron metabolism in experimental cirrhosis and cholestasis. ( Albuquerque, MR; Damião, AO; Laudanna, AA; Quintão, EC; Sipahi, AM, 1993) |
| "Most adverse drug reactions affecting the liver and producing jaundice are unpredictable, delayed in onset, and only hypothetically related to microsomal metabolism in some instances." | 2.35 | Hepatic drug metabolism and adverse hepatic drug reactions. ( Schaffner, F, 1975) |
| "TGF-β signaling links HSC activation to liver fibrosis and tumorigenesis." | 1.62 | Perivenous Stellate Cells Are the Main Source of Myofibroblasts and Cancer-Associated Fibroblasts Formed After Chronic Liver Injuries. ( Ge, G; Lin, M; Peng, YJ; Ren, Z; Shang, G; Tang, XT; Wang, SS; Yin, X; Yuan, J; Zhou, BO, 2021) |
| "In the present study, liver fibrosis was induced in wild-type (WT), TLR7-deficient, and IFN-α/β receptor-1 (IFNAR1)-deficient mice and TLR7-mediated signaling was assessed in liver cells isolated from these mice." | 1.40 | Toll-like receptor 7-mediated type I interferon signaling prevents cholestasis- and hepatotoxin-induced liver fibrosis. ( Kim, B; Kim, JW; Lim, CW; Park, S; Roh, YS; Seki, E, 2014) |
| " When oral bioavailability of mizoribine was estimated by the recovery amount in the urine, rats under cholestatic states exhibited significantly higher oral bioavailabilities than untreated control rats." | 1.36 | Increased intestinal absorption of mizoribine, an immunosuppressive agent, in cholestatic rats. ( Kamio, Y; Mori, N; Murakami, T; Yokooji, T, 2010) |
| "Curcumin is a phytophenolic compound, which is highly efficacious for treating several inflammatory diseases." | 1.35 | Curcumin prevents and reverses cirrhosis induced by bile duct obstruction or CCl4 in rats: role of TGF-beta modulation and oxidative stress. ( Moreno, MG; Muriel, P; Reyes-Gordillo, K; Segovia, J; Shibayama, M; Tsutsumi, V; Vergara, P, 2008) |
| "Curcumin treatment (200 mg/kg, p." | 1.34 | Curcumin protects against acute liver damage in the rat by inhibiting NF-kappaB, proinflammatory cytokines production and oxidative stress. ( Moreno, MG; Muriel, P; Reyes-Gordillo, K; Segovia, J; Shibayama, M; Vergara, P, 2007) |
| "Administration of the non-metabolizable organic anion indocyanine green (ICG) prior to a toxic dose of acetaminophen (4-acetamidophenol; APAP) reduces liver injury 24h after dosing." | 1.33 | Cholestasis induced by model organic anions protects from acetaminophen hepatotoxicity in male CD-1 mice. ( Hennig, GE; Manautou, JE; Silva, VM, 2006) |
| " The pharmacokinetic analysis of these data showed that the decreased total plasma clearance of ICG in GAL and CCl4 rats results from both lowered influx across the sinusoidal plasma membrane of hepatocytes and the decreased hepatic plasma flow." | 1.29 | Pharmacokinetics of indocyanine green in rats with experimentally induced hepatic diseases. ( Kimura, T; Kurosaki, Y; Nakayama, S; Nakayama, T; Yamao, T, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (25.00) | 18.7374 |
| 1990's | 6 (18.75) | 18.2507 |
| 2000's | 4 (12.50) | 29.6817 |
| 2010's | 11 (34.38) | 24.3611 |
| 2020's | 3 (9.38) | 2.80 |
| Authors | Studies |
|---|---|
| Gupta, V | 1 |
| Gupta, I | 1 |
| Park, J | 1 |
| Bram, Y | 1 |
| Schwartz, RE | 1 |
| Verboven, E | 1 |
| Moya, IM | 1 |
| Sansores-Garcia, L | 1 |
| Xie, J | 1 |
| Hillen, H | 1 |
| Kowalczyk, W | 1 |
| Vella, G | 1 |
| Verhulst, S | 2 |
| Castaldo, SA | 1 |
| Algueró-Nadal, A | 1 |
| Romanelli, L | 1 |
| Mercader-Celma, C | 1 |
| Souza, NA | 1 |
| Soheily, S | 1 |
| Van Huffel, L | 1 |
| Van Brussel, T | 1 |
| Lambrechts, D | 1 |
| Roskams, T | 1 |
| Lemaigre, FP | 1 |
| Bergers, G | 1 |
| van Grunsven, LA | 2 |
| Halder, G | 1 |
| Wang, SS | 1 |
| Tang, XT | 1 |
| Lin, M | 1 |
| Yuan, J | 1 |
| Peng, YJ | 1 |
| Yin, X | 1 |
| Shang, G | 1 |
| Ge, G | 1 |
| Ren, Z | 1 |
| Zhou, BO | 1 |
| Kim, KH | 1 |
| Chen, CC | 1 |
| Monzon, RI | 1 |
| Lau, LF | 1 |
| Roh, YS | 1 |
| Park, S | 1 |
| Kim, JW | 1 |
| Lim, CW | 1 |
| Seki, E | 2 |
| Kim, B | 1 |
| Iwaisako, K | 1 |
| Jiang, C | 1 |
| Zhang, M | 1 |
| Cong, M | 1 |
| Moore-Morris, TJ | 1 |
| Park, TJ | 1 |
| Liu, X | 1 |
| Xu, J | 1 |
| Wang, P | 1 |
| Paik, YH | 1 |
| Meng, F | 1 |
| Asagiri, M | 1 |
| Murray, LA | 1 |
| Hofmann, AF | 1 |
| Iida, T | 1 |
| Glass, CK | 1 |
| Brenner, DA | 2 |
| Kisseleva, T | 1 |
| Bitencourt, S | 1 |
| Stradiot, L | 1 |
| Thoen, L | 1 |
| Mannaerts, I | 1 |
| O'Brien, A | 1 |
| China, L | 1 |
| Massey, KA | 1 |
| Nicolaou, A | 1 |
| Winstanley, A | 1 |
| Newson, J | 1 |
| Hobbs, A | 1 |
| Audzevich, T | 1 |
| Gilroy, DW | 1 |
| Siegmund, SV | 1 |
| Schlosser, M | 1 |
| Schildberg, FA | 1 |
| De Minicis, S | 1 |
| Uchinami, H | 1 |
| Kuntzen, C | 1 |
| Knolle, PA | 1 |
| Strassburg, CP | 1 |
| Schwabe, RF | 1 |
| Kopec, AK | 1 |
| Joshi, N | 1 |
| Luyendyk, JP | 1 |
| Reyes-Gordillo, K | 2 |
| Segovia, J | 2 |
| Shibayama, M | 3 |
| Tsutsumi, V | 2 |
| Vergara, P | 2 |
| Moreno, MG | 2 |
| Muriel, P | 5 |
| Rivera-Espinoza, Y | 1 |
| Mori, N | 1 |
| Yokooji, T | 1 |
| Kamio, Y | 1 |
| Murakami, T | 1 |
| Onozuka, I | 1 |
| Kakinuma, S | 1 |
| Kamiya, A | 1 |
| Miyoshi, M | 1 |
| Sakamoto, N | 1 |
| Kiyohashi, K | 1 |
| Watanabe, T | 1 |
| Funaoka, Y | 1 |
| Ueyama, M | 1 |
| Nakagawa, M | 1 |
| Koshikawa, N | 1 |
| Seiki, M | 1 |
| Nakauchi, H | 1 |
| Watanabe, M | 1 |
| Rivera, H | 1 |
| Morales-Ríos, MS | 1 |
| Bautista, W | 1 |
| Pérez-Álvarez, V | 1 |
| Fouts, DE | 1 |
| Torralba, M | 1 |
| Nelson, KE | 1 |
| Schnabl, B | 1 |
| Silva, VM | 1 |
| Hennig, GE | 1 |
| Manautou, JE | 1 |
| Spano, JS | 1 |
| August, JR | 1 |
| Henderson, RA | 1 |
| Dumas, MB | 1 |
| Groth, AH | 1 |
| Kanaghinis, T | 1 |
| Avgerinos, A | 1 |
| Scliros, P | 1 |
| Kalantzis, N | 1 |
| Hatzioannou, J | 1 |
| Nikolopoulou, P | 1 |
| Anagnostou, D | 1 |
| Katsas, A | 1 |
| Demopoulos, J | 1 |
| Rekoumis, G | 1 |
| Stathakos, D | 1 |
| Sato, N | 1 |
| Ohta, S | 1 |
| Sakurai, N | 1 |
| Kamogawa, A | 1 |
| Inoue, T | 1 |
| Shinoda, M | 1 |
| Kimura, T | 1 |
| Nakayama, S | 1 |
| Yamao, T | 1 |
| Kurosaki, Y | 1 |
| Nakayama, T | 1 |
| Saraswat, B | 1 |
| Visen, PK | 1 |
| Patnaik, GK | 1 |
| Dhawan, BN | 1 |
| Favari, L | 1 |
| Soto, C | 1 |
| Damião, AO | 1 |
| Sipahi, AM | 1 |
| Albuquerque, MR | 1 |
| Laudanna, AA | 1 |
| Quintão, EC | 1 |
| Swain, MG | 1 |
| Maric, M | 1 |
| Schaffner, F | 1 |
| Fujisaki, K | 1 |
| Idéo, G | 1 |
| Morganti, A | 1 |
| Dioguardi, N | 1 |
| Tarsoly, E | 1 |
| Kiss, A | 1 |
| Kenyeres, I | 1 |
| Buxton, BH | 1 |
| Witschi, H | 1 |
| Plaa, GL | 1 |
| Beduhn, D | 1 |
| Kampmann, H | 1 |
| Encke, A | 1 |
| Mathias, K | 1 |
3 reviews available for carbon tetrachloride and Bile Duct Obstruction
| Article | Year |
|---|---|
Role of hemostatic factors in hepatic injury and disease: animal models de-liver.
Topics: Animals; Bile Ducts; Blood Coagulation; Blood Coagulation Disorders; Carbon Tetrachloride; Chemical | 2016 |
Pharmacological actions of curcumin in liver diseases or damage.
Topics: Animals; Carbon Tetrachloride; Cholestasis; Curcuma; Curcumin; Humans; Iron; Liver; Liver Cirrhosis; | 2009 |
Hepatic drug metabolism and adverse hepatic drug reactions.
Topics: Adaptation, Biological; Animals; Biotransformation; Carbon Tetrachloride; Carbon Tetrachloride Poiso | 1975 |
29 other studies available for carbon tetrachloride and Bile Duct Obstruction
| Article | Year |
|---|---|
Hedgehog Signaling Demarcates a Niche of Fibrogenic Peribiliary Mesenchymal Cells.
Topics: Animals; Carbon Tetrachloride; Cholestasis; Female; Fibroblasts; Hedgehog Proteins; Humans; Liver; L | 2020 |
Regeneration Defects in Yap and Taz Mutant Mouse Livers Are Caused by Bile Duct Disruption and Cholestasis.
Topics: Adaptor Proteins, Signal Transducing; Animals; Bile Ducts; Carbon Tetrachloride; Cell Proliferation; | 2021 |
Perivenous Stellate Cells Are the Main Source of Myofibroblasts and Cancer-Associated Fibroblasts Formed After Chronic Liver Injuries.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Bile Ducts; Cancer-Associated Fibroblasts; Ca | 2021 |
Matricellular protein CCN1 promotes regression of liver fibrosis through induction of cellular senescence in hepatic myofibroblasts.
Topics: Animals; Binding Sites; Carbon Tetrachloride; Cells, Cultured; Cellular Senescence; Cholestasis; Cys | 2013 |
Toll-like receptor 7-mediated type I interferon signaling prevents cholestasis- and hepatotoxin-induced liver fibrosis.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cholestasis; Chronic Disease; | 2014 |
Origin of myofibroblasts in the fibrotic liver in mice.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cholestasis; Collagen Type I; | 2014 |
Inhibitory effect of dietary capsaicin on liver fibrosis in mice.
Topics: Animals; Bile Ducts; Capsaicin; Carbon Tetrachloride; Cholestasis; Diet; Disease Models, Animal; Dow | 2015 |
Bile duct-ligated mice exhibit multiple phenotypic similarities to acute decompensation patients despite histological differences.
Topics: Animals; Bile Ducts; Carbon Tetrachloride; Cholestasis; Disease Models, Animal; Humans; Ligation; Li | 2016 |
Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells.
Topics: Animals; Carbon Tetrachloride; Cell Death; Cell Proliferation; Chemokine CCL2; Chemokine CCL5; Chole | 2016 |
Curcumin prevents and reverses cirrhosis induced by bile duct obstruction or CCl4 in rats: role of TGF-beta modulation and oxidative stress.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carbon Tetrachloride; Carbon Tetrach | 2008 |
Increased intestinal absorption of mizoribine, an immunosuppressive agent, in cholestatic rats.
Topics: 1-Naphthylisothiocyanate; Administration, Oral; Animals; Biological Availability; Carbon Tetrachlori | 2010 |
Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice.
Topics: Actins; Animals; Carbon Tetrachloride; Cholestasis; Collagen Type I; Disease Progression; Liver Cirr | 2011 |
A novel fluorinated stilbene exerts hepatoprotective properties in CCl(4)-induced acute liver damage.
Topics: Animals; Anti-Inflammatory Agents; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cho | 2011 |
Bacterial translocation and changes in the intestinal microbiome in mouse models of liver disease.
Topics: Animals; Bacterial Translocation; Carbon Tetrachloride; Cholestasis; Disease Models, Animal; Intesti | 2012 |
Cholestasis induced by model organic anions protects from acetaminophen hepatotoxicity in male CD-1 mice.
Topics: Acetaminophen; Amaranth Dye; Animals; Bile Ducts; Carbon Tetrachloride; Chemical and Drug Induced Li | 2006 |
Curcumin protects against acute liver damage in the rat by inhibiting NF-kappaB, proinflammatory cytokines production and oxidative stress.
Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biom | 2007 |
Serum gamma-glutamyl transpeptidase activity in healthy cats and cats with induced hepatic disease.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Carbon Tetrachloride; Cat Diseases; Cats; Chemi | 1983 |
Plasma lipoprotein pattern in relation to liver histology after toxic hepatitis and experimental biliary obstruction in rabbits.
Topics: Alanine Transaminase; Allylisopropylacetamide; Animals; Aspartate Aminotransferases; Carbon Tetrachl | 1982 |
[Protective effects of the stem of Berchemia racemosa Sieb. et Zucc. on experimental liver injuries].
Topics: 1-Naphthylisothiocyanate; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cho | 1995 |
Pharmacokinetics of indocyanine green in rats with experimentally induced hepatic diseases.
Topics: Acute Disease; Animals; Bile; Blood Proteins; Carbon Tetrachloride; Chemical and Drug Induced Liver | 1993 |
Anticholestatic effect of picroliv, active hepatoprotective principle of Picrorhiza kurrooa, against carbon tetrachloride induced cholestasis.
Topics: Animals; Bile Acids and Salts; Carbon Tetrachloride; Cats; Cholestasis; Cinnamates; Dose-Response Re | 1993 |
Erythrocyte alterations correlate with CCl4 and biliary obstruction-induced liver damage in the rat.
Topics: Animals; Calcium-Transporting ATPases; Carbon Tetrachloride; Cell Membrane; Cholestasis; Erythrocyte | 1993 |
Chylomicron metabolism in experimental cirrhosis and cholestasis.
Topics: Animals; Carbon Tetrachloride; Cholestasis; Cholesterol; Chylomicrons; Emulsions; Lipolysis; Liver C | 1993 |
Improvement in cholestasis-associated fatigue with a serotonin receptor agonist using a novel rat model of fatigue assessment.
Topics: Animals; Bile Ducts; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cholestasis; Dise | 1997 |
[Changes and induction of drug-metabolizing enzymes in rats with hepatic injuries].
Topics: 1-Naphthylisothiocyanate; Animals; Carbon Tetrachloride; Cholestasis; Enzyme Induction; In Vitro Tec | 1986 |
Gamma-glutamyl transpeptidase: a clinical and experimental study.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bile Ducts; Carbon | 1972 |
[On the effect of jaundice on the healing of fractures].
Topics: Animals; Calcification, Physiologic; Carbon Tetrachloride; Cholestasis; Common Bile Duct; Connective | 1967 |
Biochemical changes provoked in rat liver by cholestatic doses of -naphthylisothiocyanate.
Topics: Aminopyrine N-Demethylase; Animals; Bile Ducts; Carbon Isotopes; Carbon Tetrachloride; Cholestasis; | 1973 |
[Comparative angiographic and scintigraphic studies in experimental parenchymatous and obstructive jaundice].
Topics: Alanine Transaminase; Alkaline Phosphatase; Angiography; Animals; Bilirubin; Blood Coagulation Tests | 1973 |