carbon tetrachloride has been researched along with Angiogenesis, Pathologic in 27 studies
Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Hepatic fibrosis was induced in CD248(-/-) and wild-type controls with carbon tetrachloride (CCl4) treatment." | 3.83 | CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism. ( Aldridge, V; Buckley, CD; Croft, AP; Fear, J; Garg, A; Haldar, D; Hedegaard, D; Henderson, NC; Naylor, AJ; Newsome, PN; Reynolds, GM; Weston, CJ; Wilhelm, A, 2016) |
| "Treatment with lenvatinib also suppressed platelet-derived growth factor-BB-stimulated proliferation, chemotaxis and vascular endothelial growth factor-A production, as well as basic fibroblast growth factor-induced LX-2 proliferation." | 1.62 | Lenvatinib prevents liver fibrosis by inhibiting hepatic stellate cell activation and sinusoidal capillarization in experimental liver fibrosis. ( Akahane, T; Ishida, K; Kaji, K; Kawaratani, H; Moriya, K; Namisaki, T; Nishimura, N; Ogawa, H; Takagi, H; Takaya, H; Yoshiji, H, 2021) |
| "Liver fibrosis is a common feature of liver dysfunction during chronic liver diseases and is frequently associated with angiogenesis, a dynamic process that forms new blood vessels from preexisting vasculature." | 1.62 | miR-30c inhibits angiogenesis by targeting delta-like ligand 4 in liver sinusoidal endothelial cell to attenuate liver fibrosis. ( Cai, X; Chen, L; Dong, H; Gu, T; Guo, Y; Li, B; Li, F; Lu, L; Ma, Z; Qu, Y; Shen, B; Zhang, Q, 2021) |
| "However, its roles in liver fibrosis remain to be determined." | 1.62 | Alpinetin exerts anti-inflammatory, anti-oxidative and anti-angiogenic effects through activating the Nrf2 pathway and inhibiting NLRP3 pathway in carbon tetrachloride-induced liver fibrosis. ( Chen, J; Hu, R; Li, J; Sun, J; Xing, X; Zhou, Q; Zhu, Z, 2021) |
| "MATERIAL AND METHODS A liver fibrosis mouse model induced by carbon tetrachloride (CCl4) intervention was employed in this study." | 1.51 | Gexia-Zhuyu Decoction Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in Mice Partly via Liver Angiogenesis Mediated by Myeloid Cells. ( Cao, S; Deng, Z; Ge, S; Kong, F; Pan, Z; Zhang, S, 2019) |
| "Procyanidin B2 (PB2) is a flavonoid extract abundant in grape seeds with anti-oxidant, anti-inflammatory and anti-cancer properties." | 1.51 | Procyanidin B2 inhibits the activation of hepatic stellate cells and angiogenesis via the Hedgehog pathway during liver fibrosis. ( Chen, J; Chen, K; Dai, W; Fan, X; Feng, J; Guo, C; Ji, J; Li, J; Li, S; Liu, T; Mao, Y; Wang, C; Wang, F; Wu, J; Wu, L; Yu, Q; Zhang, J; Zhou, Y, 2019) |
| "Here we established murine model of liver fibrosis and found that oroxylin A (40 mg/kg) could ameliorate angiogenesis in liver fibrosis may related to hypoxia inducible factor 1α (HIF-1α)." | 1.48 | Oroxylin A prevents angiogenesis of LSECs in liver fibrosis via inhibition of YAP/HIF-1α signaling. ( Bian, M; Chen, A; Chen, X; Guo, Q; Jin, H; Shao, J; Yang, X; Zhang, C; Zhang, F; Zhao, S; Zheng, S, 2018) |
| "The progression of liver fibrosis, an intrinsic response to chronic liver injury, is associated with hepatic hypoxia, angiogenesis, abnormal inflammation, and significant matrix deposition, leading to the development of cirrhosis and hepatocellular carcinoma (HCC)." | 1.43 | Dual-Functional Nanoparticles Targeting CXCR4 and Delivering Antiangiogenic siRNA Ameliorate Liver Fibrosis. ( Chan, KM; Chen, Y; Chern, GG; Chiang, T; Hsu, FF; Liu, CH; Liu, JY; Liu, YC; Wu, YH, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (11.11) | 29.6817 |
| 2010's | 18 (66.67) | 24.3611 |
| 2020's | 6 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, Y | 1 |
| Ge, X | 1 |
| Wang, SN | 1 |
| Zhang, CQ | 1 |
| Xue, X | 1 |
| Zhao, X | 1 |
| Wang, J | 1 |
| Wang, C | 2 |
| Ma, C | 1 |
| Zhang, Y | 1 |
| Li, Y | 1 |
| Peng, C | 1 |
| Liu, HL | 1 |
| Lv, J | 1 |
| Zhao, ZM | 1 |
| Xiong, AM | 1 |
| Tan, Y | 1 |
| Glenn, JS | 1 |
| Tao, YY | 1 |
| Weng, HL | 1 |
| Liu, CH | 4 |
| Osawa, Y | 1 |
| Yoshio, S | 1 |
| Aoki, Y | 1 |
| Korenaga, M | 1 |
| Imamura, M | 1 |
| Oide, T | 1 |
| Okawara, M | 1 |
| Kawai, H | 1 |
| Tsutsui, Y | 1 |
| Yoshida, Y | 1 |
| Yoshikawa, S | 1 |
| Mori, T | 1 |
| Yamazoe, T | 1 |
| Kanto, T | 1 |
| Ogawa, H | 1 |
| Kaji, K | 1 |
| Nishimura, N | 1 |
| Takagi, H | 1 |
| Ishida, K | 1 |
| Takaya, H | 1 |
| Kawaratani, H | 1 |
| Moriya, K | 1 |
| Namisaki, T | 1 |
| Akahane, T | 1 |
| Yoshiji, H | 1 |
| Gu, T | 1 |
| Shen, B | 1 |
| Li, B | 1 |
| Guo, Y | 1 |
| Li, F | 1 |
| Ma, Z | 1 |
| Chen, L | 2 |
| Zhang, Q | 1 |
| Qu, Y | 1 |
| Dong, H | 1 |
| Cai, X | 1 |
| Lu, L | 1 |
| Zhu, Z | 1 |
| Hu, R | 1 |
| Li, J | 2 |
| Xing, X | 1 |
| Chen, J | 3 |
| Zhou, Q | 1 |
| Sun, J | 1 |
| Li, X | 1 |
| Yao, QY | 1 |
| Liu, HC | 1 |
| Jin, QW | 1 |
| Xu, BL | 1 |
| Zhang, SC | 1 |
| Tu, CT | 1 |
| Zhang, C | 2 |
| Bian, M | 1 |
| Chen, X | 1 |
| Jin, H | 2 |
| Zhao, S | 3 |
| Yang, X | 1 |
| Shao, J | 4 |
| Chen, A | 3 |
| Guo, Q | 1 |
| Zhang, F | 5 |
| Zheng, S | 5 |
| Ali, MM | 1 |
| H Borai, I | 1 |
| Ghanem, HM | 1 |
| H Abdel-Halim, A | 1 |
| Mousa, FM | 1 |
| Deng, Z | 1 |
| Zhang, S | 1 |
| Ge, S | 1 |
| Kong, F | 1 |
| Cao, S | 2 |
| Pan, Z | 1 |
| Feng, J | 1 |
| Liu, T | 1 |
| Wu, L | 2 |
| Yu, Q | 1 |
| Li, S | 1 |
| Zhou, Y | 1 |
| Zhang, J | 1 |
| Ji, J | 1 |
| Chen, K | 1 |
| Mao, Y | 1 |
| Wang, F | 1 |
| Dai, W | 1 |
| Fan, X | 1 |
| Wu, J | 1 |
| Guo, C | 1 |
| Ehling, J | 1 |
| Bartneck, M | 1 |
| Wei, X | 1 |
| Gremse, F | 1 |
| Fech, V | 1 |
| Möckel, D | 1 |
| Baeck, C | 1 |
| Hittatiya, K | 1 |
| Eulberg, D | 1 |
| Luedde, T | 1 |
| Kiessling, F | 1 |
| Trautwein, C | 1 |
| Lammers, T | 1 |
| Tacke, F | 1 |
| Zhang, Z | 3 |
| Kong, D | 1 |
| Zhang, X | 1 |
| Lu, C | 1 |
| Lu, Y | 1 |
| Wilhelm, A | 1 |
| Aldridge, V | 1 |
| Haldar, D | 1 |
| Naylor, AJ | 1 |
| Weston, CJ | 1 |
| Hedegaard, D | 1 |
| Garg, A | 1 |
| Fear, J | 1 |
| Reynolds, GM | 1 |
| Croft, AP | 1 |
| Henderson, NC | 1 |
| Buckley, CD | 1 |
| Newsome, PN | 1 |
| You, Q | 1 |
| Kong, LJ | 1 |
| Li, FD | 1 |
| Wang, HY | 1 |
| Liu, DG | 1 |
| Pei, FH | 1 |
| Song, JT | 1 |
| Xu, J | 1 |
| Zhou, YN | 1 |
| Mu, YP | 1 |
| Fu, WW | 1 |
| Ning, BB | 1 |
| Du, GL | 1 |
| Chen, JM | 1 |
| Sun, MY | 2 |
| Zhang, H | 1 |
| Hu, YY | 2 |
| Xu, LM | 2 |
| Liu, P | 2 |
| Chan, KM | 1 |
| Chiang, T | 1 |
| Liu, JY | 1 |
| Chern, GG | 1 |
| Hsu, FF | 1 |
| Wu, YH | 1 |
| Liu, YC | 1 |
| Chen, Y | 1 |
| Wu, K | 1 |
| Huang, R | 1 |
| Wu, H | 1 |
| Liu, Y | 1 |
| Yang, C | 1 |
| Hou, X | 1 |
| Chen, B | 1 |
| DaI, J | 1 |
| Wu, C | 1 |
| Qian, L | 1 |
| Lin, Q | 1 |
| Hao, M | 1 |
| Yao, Z | 2 |
| Lian, N | 1 |
| Öztürk Akcora, B | 1 |
| Storm, G | 1 |
| Prakash, J | 1 |
| Bansal, R | 1 |
| Takahara, T | 1 |
| Xue, F | 1 |
| Mazzone, M | 1 |
| Yata, Y | 1 |
| Nonome, K | 1 |
| Kanayama, M | 1 |
| Kawai, K | 1 |
| Pisacane, AM | 1 |
| Takahara, S | 1 |
| Li, XK | 1 |
| Comoglio, PM | 1 |
| Sugiyama, T | 1 |
| Michieli, P | 1 |
| Vanheule, E | 1 |
| Geerts, AM | 1 |
| Van Huysse, J | 1 |
| Schelfhout, D | 1 |
| Praet, M | 1 |
| Van Vlierberghe, H | 1 |
| De Vos, M | 1 |
| Colle, I | 1 |
| Du, JX | 1 |
| Tao, Q | 1 |
| Zhang, LJ | 1 |
| Chen, GF | 1 |
| Cramer, T | 1 |
| Schuppan, D | 1 |
| Bauer, M | 1 |
| Pfander, D | 1 |
| Neuhaus, P | 1 |
| Herbst, H | 1 |
27 other studies available for carbon tetrachloride and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Olmesartan Improves Hepatic Sinusoidal Remodeling in Mice with Carbon Tetrachloride-Induced Liver Fibrosis.
Topics: Angiotensin II; Animals; Carbon Tetrachloride; Collagen; Imidazoles; Interleukin-10; Liver Cirrhosis | 2022 |
Carthami flos extract against carbon tetrachloride-induced liver fibrosis via alleviating angiogenesis in mice.
Topics: Animals; Carbon Tetrachloride; Collagen; Helianthus; Hepatic Stellate Cells; Liver; Liver Cirrhosis; | 2023 |
Fuzhenghuayu Decoction ameliorates hepatic fibrosis by attenuating experimental sinusoidal capillarization and liver angiogenesis.
Topics: Animals; Capillaries; Carbon Tetrachloride; Disease Models, Animal; Drugs, Chinese Herbal; Endotheli | 2019 |
Blood angiopoietin-2 predicts liver angiogenesis and fibrosis in hepatitis C patients.
Topics: Angiopoietin-2; Animals; Antiviral Agents; Carbon Tetrachloride; Hepatitis C, Chronic; Humans; Liver | 2021 |
Lenvatinib prevents liver fibrosis by inhibiting hepatic stellate cell activation and sinusoidal capillarization in experimental liver fibrosis.
Topics: Animals; Capillaries; Carbon Tetrachloride; Cells, Cultured; Hepatic Stellate Cells; Liver; Liver Ci | 2021 |
miR-30c inhibits angiogenesis by targeting delta-like ligand 4 in liver sinusoidal endothelial cell to attenuate liver fibrosis.
Topics: Adaptor Proteins, Signal Transducing; Adult; Animals; Calcium-Binding Proteins; Carbon Tetrachloride | 2021 |
Alpinetin exerts anti-inflammatory, anti-oxidative and anti-angiogenic effects through activating the Nrf2 pathway and inhibiting NLRP3 pathway in carbon tetrachloride-induced liver fibrosis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carbon Tetrachloride; Collagen; Disease Models, Ani | 2021 |
Placental growth factor silencing ameliorates liver fibrosis and angiogenesis and inhibits activation of hepatic stellate cells in a murine model of chronic liver disease.
Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Chronic Disease; Disease Models, | 2017 |
Oroxylin A prevents angiogenesis of LSECs in liver fibrosis via inhibition of YAP/HIF-1α signaling.
Topics: Adaptor Proteins, Signal Transducing; Angiopoietin-2; Animals; Carbon Tetrachloride; Cell Cycle Prot | 2018 |
The prophylactic and therapeutic effects of Momordica charantia methanol extract through controlling different hallmarks of the hepatocarcinogenesis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carbon Tetrachloride; Carcinogenesis; Cell Proliferation; | 2018 |
Gexia-Zhuyu Decoction Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in Mice Partly via Liver Angiogenesis Mediated by Myeloid Cells.
Topics: Angiogenesis Inducing Agents; Animals; Bone Marrow Cells; Carbon Tetrachloride; Disease Models, Anim | 2019 |
Procyanidin B2 inhibits the activation of hepatic stellate cells and angiogenesis via the Hedgehog pathway during liver fibrosis.
Topics: Animals; Biflavonoids; Carbon Tetrachloride; Catechin; Cell Line; Cell Proliferation; Down-Regulatio | 2019 |
CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis.
Topics: Animals; Aptamers, Nucleotide; Carbon Tetrachloride; Chemokine CCL2; Disease Models, Animal; Disease | 2014 |
Curcumin attenuates angiogenesis in liver fibrosis and inhibits angiogenic properties of hepatic stellate cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Carbon Tetrachloride; Cell Proliferati | 2014 |
CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism.
Topics: Actins; Angiogenesis Inducing Agents; Animals; Antigens, CD; Antigens, Neoplasm; Becaplermin; Carbon | 2016 |
Human recombinant endostatin Endostar attenuates hepatic sinusoidal endothelial cell capillarization in CCl4‑induced fibrosis in mice.
Topics: Angiogenesis Inhibitors; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dise | 2015 |
Yiguanjian decoction and its ingredients inhibit angiogenesis in carbon tetrachloride-induced cirrhosis mice.
Topics: Actins; Angiogenesis Inhibitors; Animals; Carbon Tetrachloride; Collagen; Drugs, Chinese Herbal; Hyd | 2015 |
Dual-Functional Nanoparticles Targeting CXCR4 and Delivering Antiangiogenic siRNA Ameliorate Liver Fibrosis.
Topics: Angiogenesis Inhibitors; Animals; Benzylamines; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cyc | 2016 |
Collagen-binding vascular endothelial growth factor attenuates CCl4-induced liver fibrosis in mice.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Collagen; Disease Models, Animal; Hepatic Stellate Cells; | 2016 |
Tetramethylpyrazine attenuates carbon tetrachloride-caused liver injury and fibrogenesis and reduces hepatic angiogenesis in rats.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; bcl-2-Associated X Protein; Becaplermin; Carbon Tetrach | 2017 |
Canonical hedgehog signalling regulates hepatic stellate cell-mediated angiogenesis in liver fibrosis.
Topics: Animals; Benzoquinones; Carbon Tetrachloride; Disease Models, Animal; Hedgehog Proteins; Hepatic Ste | 2017 |
Tetramethylpyrazine attenuates sinusoidal angiogenesis via inhibition of hedgehog signaling in liver fibrosis.
Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Gene Expression Regulation; Hedgehog Proteins; Hu | 2017 |
Tyrosine kinase inhibitor BIBF1120 ameliorates inflammation, angiogenesis and fibrosis in CCl
Topics: 3T3 Cells; Animals; Carbon Tetrachloride; Disease Models, Animal; Humans; Indoles; Inflammation; Liv | 2017 |
Metron factor-1 prevents liver injury without promoting tumor growth and metastasis.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cells | 2008 |
An intravital microscopic study of the hepatic microcirculation in cirrhotic mice models: relationship between fibrosis and angiogenesis.
Topics: Animals; Bile Ducts; Carbon Tetrachloride; Ligation; Liver; Liver Cirrhosis, Biliary; Liver Cirrhosi | 2008 |
[Chinese herbal medicine Xiayuxue Decoction inhibits liver angiogenesis in rats with carbon tetrachloride-induced liver fibrosis].
Topics: Actins; Animals; Carbon Tetrachloride; CD55 Antigens; Drugs, Chinese Herbal; Liver; Liver Cirrhosis, | 2011 |
Hepatocyte growth factor and c-Met expression in rat and human liver fibrosis.
Topics: Animals; Carbon Tetrachloride; Female; Gene Expression; Hepatocyte Growth Factor; Humans; In Situ Hy | 2004 |