carbon tetrachloride has been researched along with Aging in 36 studies
Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Because the expression is reduced by carbon tetrachloride, one can speculate that the expression is modulated by oxidative stress increased with aging." | 4.82 | Senescence marker protein-30 as a novel antiaging molecule. ( Feng, D; Ishigami, A; Kondo, Y; Kuramoto, M; Machida, T; Maruyama, N, 2004) |
| "The increasing incidence of chronic liver fibrosis is one of the major health challenges in the world." | 1.72 | HBO1 as an Important Target for the Treatment of CCL4-Induced Liver Fibrosis and Aged-Related Liver Aging and Fibrosis. ( Lan, H; Li, H; Xing, B, 2022) |
| "The incidence of liver cancer is higher in men than in women." | 1.43 | Influence of sex and developmental stage on acute hepatotoxic and inflammatory responses to liver procarcinogens in the mouse. ( Grant, DM; Hanna, D; Riedmaier, AE; Sugamori, KS, 2016) |
| " To address this issue, we induced liver fibrosis by carbon tetrachloride (CCl(4)) chronic administration to 8-week- and 15-month-old mice." | 1.37 | Increased susceptibility to liver fibrosis with age is correlated with an altered inflammatory response. ( Abdoun, E; Collin de l'Hortet, A; Cosson, C; Fromenty, B; Gilgenkrantz, H; Guidotti, JE; Mahrouf-Yorgov, M; Mitchell, C; Slama, A, 2011) |
| "Since polyploid cells contain multiple molecular targets for genetic damage, the micronucleation index per genome unit was estimated." | 1.29 | An improved method of mouse liver micronucleus analysis: an application to age-related genetic alteration and polyploidy study. ( Delone, GV; Uryvaeva, IV, 1995) |
| " The results suggest that other factors are important determinants of age-associated changes in sensitivity to toxic chemicals." | 1.29 | Carbon tetrachloride hepatotoxicity as a function of age in female Fischer 344 rats. ( Cai, Y; Hornbrook, KR; Rikans, LE, 1994) |
| " Liver samples were collected from these mice 5 days before (by biopsy) and 18 days after dosing with CCl4 (1 ml/kg, i." | 1.28 | Evidence of clonal proliferation of hepatocytes after carbon-tetrachloride-induced hepatic injury in PGK-1 mosaic mice. ( Kamiyama, S; Koizumi, A; Tsukada, M; Wada, Y, 1990) |
| "Frequencies of chromosomal aberrations have been shown to increase with the age in the liver cells of 101/H mice." | 1.26 | [Chromosome instability in 101/H and C57BL/6 strain mice during aging]. ( Lil'p, IG, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (41.67) | 18.7374 |
| 1990's | 4 (11.11) | 18.2507 |
| 2000's | 8 (22.22) | 29.6817 |
| 2010's | 6 (16.67) | 24.3611 |
| 2020's | 3 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 1 |
| Xian, L | 1 |
| Zheng, R | 1 |
| Wang, Y | 1 |
| Wan, X | 1 |
| Liu, Y | 2 |
| Xing, B | 2 |
| Lan, H | 2 |
| Li, H | 2 |
| Amor, C | 1 |
| Feucht, J | 1 |
| Leibold, J | 1 |
| Ho, YJ | 1 |
| Zhu, C | 1 |
| Alonso-Curbelo, D | 1 |
| Mansilla-Soto, J | 1 |
| Boyer, JA | 1 |
| Li, X | 1 |
| Giavridis, T | 1 |
| Kulick, A | 1 |
| Houlihan, S | 1 |
| Peerschke, E | 1 |
| Friedman, SL | 1 |
| Ponomarev, V | 1 |
| Piersigilli, A | 1 |
| Sadelain, M | 1 |
| Lowe, SW | 1 |
| Collins, BH | 1 |
| Holzknecht, ZE | 1 |
| Lynn, KA | 1 |
| Sempowski, GD | 1 |
| Smith, CC | 1 |
| Liu, S | 1 |
| Parker, W | 1 |
| Rockey, DC | 1 |
| Yang, X | 1 |
| Liang, L | 1 |
| Zong, C | 1 |
| Lai, F | 1 |
| Zhu, P | 1 |
| Jiang, J | 1 |
| Yang, Y | 1 |
| Gao, L | 1 |
| Ye, F | 1 |
| Zhao, Q | 1 |
| Li, R | 1 |
| Han, Z | 1 |
| Wei, L | 1 |
| Hanna, D | 1 |
| Riedmaier, AE | 1 |
| Sugamori, KS | 1 |
| Grant, DM | 1 |
| Kim, HY | 1 |
| Kim, JH | 1 |
| Lee, SA | 1 |
| Chang, HE | 1 |
| Park, MH | 1 |
| Hwang, SJ | 1 |
| Lee, JY | 1 |
| Mok, C | 1 |
| Hong, SG | 1 |
| Wu, H | 1 |
| McBride, TJ | 1 |
| Isanhart, JP | 1 |
| Cox, SB | 1 |
| Hooper, MJ | 1 |
| Cerrada-Gimenez, M | 1 |
| Pietilä, M | 1 |
| Loimas, S | 1 |
| Pirinen, E | 1 |
| Hyvönen, MT | 1 |
| Keinänen, TA | 1 |
| Jänne, J | 1 |
| Alhonen, L | 1 |
| Mahrouf-Yorgov, M | 1 |
| Collin de l'Hortet, A | 1 |
| Cosson, C | 1 |
| Slama, A | 1 |
| Abdoun, E | 1 |
| Guidotti, JE | 1 |
| Fromenty, B | 1 |
| Mitchell, C | 1 |
| Gilgenkrantz, H | 1 |
| Li, ZF | 1 |
| Zhao, XF | 1 |
| Zhang, TT | 1 |
| Gagliano, N | 1 |
| Arosio, B | 1 |
| Grizzi, F | 1 |
| Vergani, C | 1 |
| Annoni, G | 1 |
| GALLAGHER, CH | 1 |
| POST, J | 1 |
| KLEIN, A | 1 |
| HOFFMAN, J | 1 |
| Murali, B | 1 |
| Korrapati, MC | 1 |
| Warbritton, A | 1 |
| Latendresse, JR | 1 |
| Mehendale, HM | 1 |
| Feng, D | 1 |
| Kondo, Y | 1 |
| Ishigami, A | 1 |
| Kuramoto, M | 1 |
| Machida, T | 1 |
| Maruyama, N | 1 |
| López-Diazguerrero, NE | 1 |
| Luna-López, A | 1 |
| Gutiérrez-Ruiz, MC | 1 |
| Zentella, A | 1 |
| Königsberg, M | 1 |
| Filimonov, PN | 1 |
| Sukhenko, TG | 1 |
| Gavrilova, NI | 1 |
| Shkurupii, VA | 1 |
| Natarajan, SK | 1 |
| Thomas, S | 1 |
| Ramachandran, A | 1 |
| Pulimood, AB | 1 |
| Balasubramanian, KA | 1 |
| Proctor, E | 1 |
| Chatamra, K | 1 |
| Lil'p, IG | 1 |
| Murota, S | 1 |
| Morita, I | 1 |
| Uryvaeva, IV | 1 |
| Delone, GV | 1 |
| Rikans, LE | 1 |
| Hornbrook, KR | 1 |
| Cai, Y | 1 |
| Draper, HH | 1 |
| Agarwal, S | 1 |
| Nelson, DE | 1 |
| Wee, JJ | 1 |
| Ghoshal, AK | 1 |
| Farber, E | 1 |
| Cagen, SZ | 3 |
| Gibson, JE | 2 |
| Dent, JG | 1 |
| McCormack, KM | 1 |
| Rickert, DE | 1 |
| Klaassen, CD | 1 |
| Mukhtar, H | 1 |
| Bend, JR | 1 |
| Wada, Y | 1 |
| Tsukada, M | 1 |
| Kamiyama, S | 1 |
| Koizumi, A | 1 |
| Peters, T | 1 |
| de Néchaud, B | 1 |
| Uriel, J | 1 |
| Lal, S | 1 |
| Sourkes, TL | 1 |
| Elger, J | 1 |
| Volkmann, HJ | 1 |
| Wahrenberg, I | 1 |
| Klinger, W | 1 |
| Curtis, HJ | 1 |
| Tilley, J | 1 |
| Verin, VK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study of Losartan to Reduce Radiation Induced Fibrosis in Breast Cancer Patients[NCT05637216] | Phase 2 | 40 participants (Anticipated) | Interventional | 2023-08-17 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for carbon tetrachloride and Aging
| Article | Year |
|---|---|
Senescence marker protein-30 as a novel antiaging molecule.
Topics: Aging; Animals; Binding Sites; Blotting, Western; Calcium-Binding Proteins; Carbon Tetrachloride; Ce | 2004 |
35 other studies available for carbon tetrachloride and Aging
| Article | Year |
|---|---|
Canthaxanthin shows anti-liver aging and anti-liver fibrosis effects by down-regulating inflammation and oxidative stress in vivo and in vitro.
Topics: Aged; Aging; Animals; Canthaxanthin; Carbon Tetrachloride; Carcinoma, Hepatocellular; Humans; Hydrog | 2022 |
HBO1 as an Important Target for the Treatment of CCL4-Induced Liver Fibrosis and Aged-Related Liver Aging and Fibrosis.
Topics: Aged; Aging; Animals; Carbon Tetrachloride; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; | 2022 |
HBO1 as an Important Target for the Treatment of CCL4-Induced Liver Fibrosis and Aged-Related Liver Aging and Fibrosis.
Topics: Aged; Aging; Animals; Carbon Tetrachloride; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; | 2022 |
HBO1 as an Important Target for the Treatment of CCL4-Induced Liver Fibrosis and Aged-Related Liver Aging and Fibrosis.
Topics: Aged; Aging; Animals; Carbon Tetrachloride; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; | 2022 |
HBO1 as an Important Target for the Treatment of CCL4-Induced Liver Fibrosis and Aged-Related Liver Aging and Fibrosis.
Topics: Aged; Aging; Animals; Carbon Tetrachloride; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; | 2022 |
Senolytic CAR T cells reverse senescence-associated pathologies.
Topics: Adenocarcinoma; Aging; Animals; Carbon Tetrachloride; Cellular Senescence; Female; Heterografts; Hum | 2020 |
Association of age-dependent liver injury and fibrosis with immune cell populations.
Topics: Age Factors; Aging; Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced L | 2013 |
Kupffer cells-dependent inflammation in the injured liver increases recruitment of mesenchymal stem cells in aging mice.
Topics: Age Factors; Aging; Animals; Carbon Tetrachloride; Cell Movement; Cells, Cultured; Chemical and Drug | 2016 |
Influence of sex and developmental stage on acute hepatotoxic and inflammatory responses to liver procarcinogens in the mouse.
Topics: Aging; Alanine Transaminase; Aminobiphenyl Compounds; Animals; Animals, Newborn; Carbon Tetrachlorid | 2016 |
Saengshik, a formulated health food, prevents liver damage in CCl4-induced mice and increases antioxidant activity in elderly women.
Topics: Agaricales; Aged; Aging; Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Live | 2008 |
Responses of glutamate cysteine ligase and glutathione to oxidants in deer mice (Peromyscus maniculatus).
Topics: Aging; Animals; Brain; Carbon Tetrachloride; Copper; Female; Glutamate-Cysteine Ligase; Glutathione; | 2009 |
Continuous oxidative stress due to activation of polyamine catabolism accelerates aging and protects against hepatotoxic insults.
Topics: Acetyltransferases; Aging; Animals; Carbon Tetrachloride; Liver; Male; Mice; Mice, Transgenic; Oxida | 2011 |
Increased susceptibility to liver fibrosis with age is correlated with an altered inflammatory response.
Topics: Aging; Animals; Carbon Tetrachloride; Cell Proliferation; Chronic Disease; Disease Susceptibility; H | 2011 |
[A preliminary study of anti-aging and wound healing of recombination cytoglobin].
Topics: Adenoviridae; Aging; Alanine Transaminase; Animals; Antioxidants; Carbon Tetrachloride; Catalase; Ce | 2012 |
Acute liver CCl(4) intoxication causes low HSP70 gene expression and a delayed transition through the cell cycle in aged rats.
Topics: Aging; Alanine Transaminase; Albumins; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; C | 2002 |
Ageing of mitochondria.
Topics: Aging; Carbon Tetrachloride; Edetic Acid; Mitochondria | 1960 |
Responses of the liver to injury. Effects of age upon the healing pattern after acute carbon tetrachloride poisoning.
Topics: Aging; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Liver; Wound Healing | 1960 |
Tolerance of aged Fischer 344 rats against chlordecone-amplified carbon tetrachloride toxicity.
Topics: Aging; Animals; Blotting, Western; Carbon Tetrachloride; Cell Nucleus; Chemical and Drug Induced Liv | 2004 |
Susceptibility of DNA to oxidative stressors in young and aging mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Animals; Carbon Tetrachloride; Cells, Cultured; Chromatography, | 2005 |
Effect of IFN-alpha on CC1 4-induced fibrosis of the liver and immune status in mice of different age.
Topics: Aging; Animals; Carbon Tetrachloride; Cells, Cultured; Interferon-alpha; Liver Cirrhosis, Experiment | 2005 |
Retinoid metabolism during development of liver cirrhosis.
Topics: Aging; Animals; Carbon Tetrachloride; Disease Progression; Female; Liver Cirrhosis, Experimental; Ma | 2005 |
Controlled induction of cirrhosis in the rat.
Topics: Aging; Animals; Ascites; Body Weight; Carbon Tetrachloride; Dose-Response Relationship, Drug; Liver; | 1983 |
[Chromosome instability in 101/H and C57BL/6 strain mice during aging].
Topics: Aging; Animals; Bone Marrow; Carbon Tetrachloride; Chromosome Aberrations; Liver; Male; Mice; Mice, | 1982 |
Prostaglandin-synthesizing system in rat liver: changes with aging and various stimuli.
Topics: Aging; Animals; Arachidonic Acids; Carbon Tetrachloride; Cytosol; Liver; Liver Regeneration; Male; M | 1980 |
An improved method of mouse liver micronucleus analysis: an application to age-related genetic alteration and polyploidy study.
Topics: Administration, Inhalation; Aging; Animals; Carbon Tetrachloride; Cell Division; Cell Separation; He | 1995 |
Carbon tetrachloride hepatotoxicity as a function of age in female Fischer 344 rats.
Topics: Aging; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Biotransformation; Ca | 1994 |
Effects of peroxidative stress and age on the concentration of a deoxyguanosine-malondialdehyde adduct in rat DNA.
Topics: Aging; Animals; Brain Chemistry; Carbon Tetrachloride; Cod Liver Oil; Corn Oil; Deoxyguanosine; Diet | 1995 |
Ouabain lethality as a measure of biliary function in developing mice and rats and effect of polybrominated biphenyls.
Topics: Aging; Animals; Animals, Newborn; Bile; Biphenyl Compounds; Carbon Tetrachloride; Diet; Female; Inje | 1977 |
Effect of polybrominated biphenyls on the development of hepatic excretory function.
Topics: Aging; Animals; Animals, Newborn; Biphenyl Compounds; Body Weight; Carbon Tetrachloride; Digoxin; Fe | 1979 |
Hepatotoxicity of carbon tetrachloride in developing rats.
Topics: Acetoacetates; Aging; Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver I | 1979 |
Serum glutathione S-transferases: perinatal development, sex difference, and effect of carbon tetrachloride administration on enzyme activity in the rat.
Topics: Aging; Animals; Carbon Tetrachloride; Female; Fetus; Glutathione Transferase; Guinea Pigs; Kinetics; | 1977 |
Evidence of clonal proliferation of hepatocytes after carbon-tetrachloride-induced hepatic injury in PGK-1 mosaic mice.
Topics: Aging; Animals; Carbon Tetrachloride; Cell Division; Chemical and Drug Induced Liver Injury; Clone C | 1990 |
Biosynthesis of rat serum albumin. VII. Effects observed in liver slices.
Topics: Aging; Albumins; Amino Acids; Animals; Carbon Isotopes; Carbon Tetrachloride; Fasting; Female; Globu | 1973 |
[Transitory cell antigens of rat liver. I. The secretion and synthesis of fetospecific serum proteins during hepatic development and regeneration].
Topics: Aging; Amniotic Fluid; Animals; Animals, Newborn; Blood Proteins; Cadmium; Carbon Isotopes; Carbon T | 1971 |
The effect of chronic administration of carbon tetrachloride and alpha-napthylisothiocyanate on tissue copper levels in the rat.
Topics: Aging; Animals; Bone and Bones; Brain; Carbon Tetrachloride; Copper; Diaphragm; Hair; Heart; Kidney; | 1970 |
[Age-dependent normal activities of GOT, GPT and histidase in liver homogenate and serum of rats, and age-dependent changes of the enzyme activities after administration of carbon-tetrachloride].
Topics: Aging; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Enzyme Acti | 1970 |
Chromosome aberrations in liver forced to regenerate by chemical or surgical methods.
Topics: Aging; Animals; Carbon Tetrachloride; Chromosome Aberrations; Hepatectomy; Liver; Liver Regeneration | 1968 |
[Characteristics of experimental liver cirrhosis related to the age of the animal].
Topics: Aging; Animals; Bile; Carbon Tetrachloride; DNA; Fatty Liver; Glycogen; Lipid Metabolism; Liver; Liv | 1968 |