Page last updated: 2024-10-16

carbon monoxide and Thalassemia

carbon monoxide has been researched along with Thalassemia in 11 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Thalassemia: A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.

Research Excerpts

ExcerptRelevanceReference
"In this study, the authors examined a possible role of measurements of end-tidal carbon monoxide (CO), corrected for inhaled CO (ETCOc), as a noninvasive screening tool for hemoglobinopathies and as an indicator for when transfusions would be required in patients receiving chronic transfusions."7.76Elevated exhaled carbon monoxide concentration in hemoglobinopathies and its relation to red blood cell transfusion therapy. ( Golden, DW; Hall, JY; Harmatz, P; James, EB; Schumacher, L; Simon, J; Stevenson, DK; Vichinsky, E; Vreman, HJ; Wong, RJ, 2010)
"In this study, the authors examined a possible role of measurements of end-tidal carbon monoxide (CO), corrected for inhaled CO (ETCOc), as a noninvasive screening tool for hemoglobinopathies and as an indicator for when transfusions would be required in patients receiving chronic transfusions."3.76Elevated exhaled carbon monoxide concentration in hemoglobinopathies and its relation to red blood cell transfusion therapy. ( Golden, DW; Hall, JY; Harmatz, P; James, EB; Schumacher, L; Simon, J; Stevenson, DK; Vichinsky, E; Vreman, HJ; Wong, RJ, 2010)
"The rate of endogenous carbon monoxide production ( Vco), determined by the closed rebreathing system technique, was elevated above the normal range in four of five patients studied with ineffective erythropoiesis (four patients with primary refractory anemia, one with thalassemia)."3.64Carbon monoxide production associated with ineffective erythropoiesis. ( Coburn, RF; Goldwein, MI; Rother, ML; Shafer, BC; White, P; Williams, WJ, 1967)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's2 (18.18)18.2507
2000's0 (0.00)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lei, MQ1
Sun, LF1
Luo, XS1
Yang, XY1
Yu, F1
Chen, XX1
Wang, ZM1
James, EB1
Vreman, HJ1
Wong, RJ1
Stevenson, DK1
Vichinsky, E1
Schumacher, L1
Hall, JY1
Simon, J1
Golden, DW1
Harmatz, P1
Brillet, T1
Baudin-Creuza, V1
Vasseur, C1
Domingues-Hamdi, E1
Kiger, L1
Wajcman, H1
Pissard, S1
Marden, MC1
LEE, GR1
HAUT, A1
CAINE, TH1
CARTWRIGHT, GE1
WINTROBE, MM1
White, P1
Coburn, RF1
Williams, WJ1
Goldwein, MI1
Rother, ML1
Shafer, BC1
Chan, GC1
Lau, YL1
Yeung, CY1
Ruymann, FB1
Popejoy, LA1
Brouillard, RB1
Sannolo, N1
Farina, V1
Fiorillo, A1
Pimstone, NR1
Engel, RR1
Rodkey, FL1
Krill, CE1
Neer, EJ1

Reviews

1 review available for carbon monoxide and Thalassemia

ArticleYear
Renal degradation of hemoglobin.
    Seminars in hematology, 1972, Volume: 9, Issue:1

    Topics: Amino Acids; Anemia, Hemolytic; Anemia, Sickle Cell; Animals; Bilirubin; Carbon Isotopes; Carbon Mon

1972

Other Studies

10 other studies available for carbon monoxide and Thalassemia

ArticleYear
Distinguishing iron deficiency anemia from thalassemia by the red blood cell lifespan with a simple CO breath test: a pilot study.
    Journal of breath research, 2019, 03-06, Volume: 13, Issue:2

    Topics: Adult; Anemia, Iron-Deficiency; Breath Tests; Carbon Monoxide; Diagnosis, Differential; Erythrocyte

2019
Elevated exhaled carbon monoxide concentration in hemoglobinopathies and its relation to red blood cell transfusion therapy.
    Pediatric hematology and oncology, 2010, Volume: 27, Issue:2

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Breath Tests; Carbon Monoxide; Child; Child, Preschool; Cros

2010
Alpha-hemoglobin stabilizing protein (AHSP), a kinetic scheme of the action of a human mutant, AHSPV56G.
    The Journal of biological chemistry, 2010, Jun-04, Volume: 285, Issue:23

    Topics: Blood Proteins; Carbon Monoxide; Child; Circular Dichroism; Fluorescence Resonance Energy Transfer;

2010
THE CHROMATOGRAPHY OF HEMINS FROM NORMAL AND ABNORMAL HUMAN ERYTHROCYTES.
    Blood, 1964, Volume: 23

    Topics: Acetone; Acid-Base Equilibrium; Anemia; Anemia, Hemolytic; Anemia, Hypochromic; Carbon Monoxide; Chr

1964
Carbon monoxide production associated with ineffective erythropoiesis.
    The Journal of clinical investigation, 1967, Volume: 46, Issue:12

    Topics: Adolescent; Adult; Aged; Anemia; Anemia, Sideroblastic; Bile Pigments; Bilirubin; Carbon Isotopes; C

1967
End tidal carbon monoxide concentration in childhood haemolytic disorders.
    Journal of paediatrics and child health, 1998, Volume: 34, Issue:5

    Topics: Adolescent; Breath Tests; Carbon Monoxide; Carboxyhemoglobin; Case-Control Studies; Child; Child, Pr

1998
Splenic sequestration and ineffective erythropoiesis in hemoglobin E-beta-thalassemia disease.
    Pediatric research, 1978, Volume: 12, Issue:10

    Topics: Adolescent; Carbon Monoxide; Erythrocyte Aging; Erythrocytes; Erythropoiesis; Female; Fetal Hemoglob

1978
Abnormal endogenous carbon monoxide production in children with ineffective erythropoiesis.
    Annals of clinical biochemistry, 1992, Volume: 29 ( Pt 4)

    Topics: Adolescent; Blood Transfusion; Carbon Monoxide; Carboxyhemoglobin; Child; Child, Preschool; Erythrop

1992
Carboxyhemoglobin levels as an index of hemolysis.
    Pediatrics, 1971, Volume: 47, Issue:4

    Topics: Adolescent; Adult; Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Anemia, Sickle Cell; Carbon Mon

1971
The reactions of the sulfhydryl groups of human hemoglobin beta 4.
    The Journal of biological chemistry, 1970, Feb-10, Volume: 245, Issue:3

    Topics: Alkylation; Carbon Isotopes; Carbon Monoxide; Chemical Phenomena; Chemistry; Ethylmaleimide; Hemoglo

1970