Page last updated: 2024-10-16

carbon monoxide and Schizophrenia

carbon monoxide has been researched along with Schizophrenia in 18 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
"Sixty smokers with schizophrenia were recruited and randomized to receive either varenicline or placebo."9.22Adjunctive varenicline treatment for smoking reduction in patients with schizophrenia: A randomized double-blind placebo-controlled trial. ( Jeon, DW; Jung, DU; Kim, SJ; Kong, BG; Moon, JJ; Oh, MK; Seo, YS; Shim, JC, 2016)
"This proof-of-concept study investigated the feasibility and initial efficacy of combining a contingency management intervention with bupropion to reduce smoking in people with schizophrenia."9.15Effects of contingency management and bupropion on cigarette smoking in smokers with schizophrenia. ( Kaplan, GB; Reid, N; Rohsenow, DJ; Swift, RM; Tidey, JW, 2011)
"The objective of this study was to examine whether there is a benefit of adding bupropion SR to high-dose combination nicotine replacement therapy (NRT) and weekly group cognitive behavioral therapy (CBT) for smoking reduction or cessation in schizophrenia."9.12A 12-week double-blind, placebo-controlled study of bupropion sr added to high-dose dual nicotine replacement therapy for smoking cessation or reduction in schizophrenia. ( Birnbaum, A; Cather, C; Culhane, MA; Evins, AE; Freudenreich, O; Goff, DC; Henderson, DC; Horowitz, J; Hsieh, E; Rigotti, NA; Schoenfeld, DA, 2007)
"The purpose of this study was to determine the effectiveness of nicotine-patch therapy for smoking cessation in patients with schizophrenia."9.11The effectiveness of nicotine-patch therapy for smoking cessation in patients with schizophrenia. ( Chen, R; Chou, KR; Ku, CH; Lee, JF; Lu, RB, 2004)
"This study was conducted to examine the effects of contingent monetary reinforcement (CM) for smoking reduction, with and without transdermal nicotine, on cigarette smoking in individuals with schizophrenia."9.10Contingent monetary reinforcement of smoking reductions, with and without transdermal nicotine, in outpatients with schizophrenia. ( Higgins, ST; O'Neill, SC; Tidey, JW, 2002)
" Expired carbon monoxide (CO) and serum nicotine and cotinine were measured in 89 smokers with schizophrenia and 53 control smokers immediately after smoking an afternoon cigarette."7.74Higher nicotine and carbon monoxide levels in menthol cigarette smokers with and without schizophrenia. ( Benowitz, NL; Foulds, J; Gandhi, KK; Steinberg, ML; Williams, JM; Ziedonis, DM, 2007)
"Ten patients with schizophrenia participated in 120-min free-smoking sessions when actively psychotic and free of antipsychotic medications, and again after the initiation of haloperidol treatment."7.69Haloperidol increases smoking in patients with schizophrenia. ( Freudenreich, O; Levin, ED; McEvoy, JP; Rose, JE, 1995)
"Sixty smokers with schizophrenia were recruited and randomized to receive either varenicline or placebo."5.22Adjunctive varenicline treatment for smoking reduction in patients with schizophrenia: A randomized double-blind placebo-controlled trial. ( Jeon, DW; Jung, DU; Kim, SJ; Kong, BG; Moon, JJ; Oh, MK; Seo, YS; Shim, JC, 2016)
"This proof-of-concept study investigated the feasibility and initial efficacy of combining a contingency management intervention with bupropion to reduce smoking in people with schizophrenia."5.15Effects of contingency management and bupropion on cigarette smoking in smokers with schizophrenia. ( Kaplan, GB; Reid, N; Rohsenow, DJ; Swift, RM; Tidey, JW, 2011)
"The objective of this study was to examine whether there is a benefit of adding bupropion SR to high-dose combination nicotine replacement therapy (NRT) and weekly group cognitive behavioral therapy (CBT) for smoking reduction or cessation in schizophrenia."5.12A 12-week double-blind, placebo-controlled study of bupropion sr added to high-dose dual nicotine replacement therapy for smoking cessation or reduction in schizophrenia. ( Birnbaum, A; Cather, C; Culhane, MA; Evins, AE; Freudenreich, O; Goff, DC; Henderson, DC; Horowitz, J; Hsieh, E; Rigotti, NA; Schoenfeld, DA, 2007)
"The purpose of this study was to determine the effectiveness of nicotine-patch therapy for smoking cessation in patients with schizophrenia."5.11The effectiveness of nicotine-patch therapy for smoking cessation in patients with schizophrenia. ( Chen, R; Chou, KR; Ku, CH; Lee, JF; Lu, RB, 2004)
"This study was conducted to examine the effects of contingent monetary reinforcement (CM) for smoking reduction, with and without transdermal nicotine, on cigarette smoking in individuals with schizophrenia."5.10Contingent monetary reinforcement of smoking reductions, with and without transdermal nicotine, in outpatients with schizophrenia. ( Higgins, ST; O'Neill, SC; Tidey, JW, 2002)
" Expired carbon monoxide (CO) and serum nicotine and cotinine were measured in 89 smokers with schizophrenia and 53 control smokers immediately after smoking an afternoon cigarette."3.74Higher nicotine and carbon monoxide levels in menthol cigarette smokers with and without schizophrenia. ( Benowitz, NL; Foulds, J; Gandhi, KK; Steinberg, ML; Williams, JM; Ziedonis, DM, 2007)
"Ten patients with schizophrenia participated in 120-min free-smoking sessions when actively psychotic and free of antipsychotic medications, and again after the initiation of haloperidol treatment."3.69Haloperidol increases smoking in patients with schizophrenia. ( Freudenreich, O; Levin, ED; McEvoy, JP; Rose, JE, 1995)
"Smoking cessation is possible for individuals with schizophrenia but the relapse rate is high."1.39Counseling and exercise intervention for smoking reduction in patients with schizophrenia: a feasibility study. ( Bernard, PP; Carayol, MS; Dandonneau, L; Esseul, EC; Ninot, GJ; Raymond, L; Xambo, JJ, 2013)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's8 (44.44)29.6817
2010's9 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sarramea Crespo, F1
Jaén-Moreno, MJ1
Gutiérrez-Rojas, L1
Balanzá-Martínez, V1
García-Alvarez, L1
Saiz Martínez, PA1
Garcia-Portilla, MP1
Guler, I1
Bobes, J1
Galati, S1
Städler, C1
Brunette, MF1
Ferron, JC1
Drake, RE1
Devitt, TS1
Geiger, PT1
McHugo, GJ1
Jonikas, JA1
Cook, JA1
Jeon, DW1
Shim, JC1
Kong, BG1
Moon, JJ1
Seo, YS1
Kim, SJ1
Oh, MK1
Jung, DU1
Kelly, DL1
McMahon, RP1
Weiner, E1
Boggs, DL1
Dickinson, D1
Conley, RR1
Buchanan, RW2
Tidey, JW3
Rohsenow, DJ2
Kaplan, GB2
Swift, RM2
Adolfo, AB1
Mann-Wrobel, MC1
Bennett, ME1
Weiner, EE1
Ball, MP1
Reid, N1
Williams, JM2
Gandhi, KK2
Lu, SE1
Steinberg, ML2
Benowitz, NL2
Bernard, PP1
Esseul, EC1
Raymond, L1
Dandonneau, L1
Xambo, JJ1
Carayol, MS1
Ninot, GJ1
Caponnetto, P1
Auditore, R1
Russo, C1
Cappello, GC1
Polosa, R1
O'Neill, SC1
Higgins, ST1
Pedersen, CB1
Raaschou-Nielsen, O1
Hertel, O1
Mortensen, PB1
Chou, KR1
Chen, R1
Lee, JF1
Ku, CH1
Lu, RB1
Smith, RC1
Warner-Cohen, J1
Matute, M1
Butler, E1
Kelly, E1
Vaidhyanathaswamy, S1
Khan, A1
Evins, AE1
Cather, C1
Culhane, MA1
Birnbaum, A1
Horowitz, J1
Hsieh, E1
Freudenreich, O2
Henderson, DC1
Schoenfeld, DA1
Rigotti, NA1
Goff, DC1
Foulds, J1
Ziedonis, DM1
McEvoy, JP1
Levin, ED1
Rose, JE1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Varenicline, an Alpha 4 Beta 2 Nicotinic Acetylcholine Receptor Partial Agonist, on Cognitive Dysfunction in 120 Patients With Schizophrenia: a Randomized, Double Blind, 8 Weeks Trial[NCT00523445]Phase 3120 participants (Anticipated)Interventional2007-09-30Completed
Incentives Plus Bupropion for Smoking in Schizophrenics[NCT00136760]Phase 257 participants (Actual)Interventional2003-09-30Completed
Nicotine and Smoking Cessation in Schizophrenia[NCT00307203]Phase 451 participants (Actual)Interventional1998-08-31Completed
Human Laboratory Study of Varenicline and Bupropion for Nicotine Dependence[NCT00749658]Phase 2/Phase 3121 participants (Actual)Interventional2008-11-30Completed
Nicotine and Cotinine Levels in Smokers With Schizophrenia and Schizoaffective Disorder[NCT00135772]100 participants Observational2003-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Cigarettes Smoked Per Day

(NCT00136760)
Timeframe: 3 weeks

Interventioncigarettes per day (Mean)
CM + BUP12.7
CM + PLA13.9
NR + BUP18.8
NR + PLA21.0

Urinary Cotinine

Urinary Cotinine levels at Week 4 (average of last 3 study visits) (NCT00136760)
Timeframe: 3 weeks

Interventionng/ml (Mean)
CM + BUP755
CM + PLA1102
NR + BUP1534
NR + PLA1408

Trials

11 trials available for carbon monoxide and Schizophrenia

ArticleYear
Carbon monoxide feedback in a motivational decision support system for nicotine dependence among smokers with severe mental illnesses.
    Journal of substance abuse treatment, 2013, Volume: 45, Issue:4

    Topics: Adult; Behavior Therapy; Carbon Monoxide; Decision Support Techniques; Feedback; Female; Humans; Mal

2013
Adjunctive varenicline treatment for smoking reduction in patients with schizophrenia: A randomized double-blind placebo-controlled trial.
    Schizophrenia research, 2016, Volume: 176, Issue:2-3

    Topics: Adult; Analysis of Variance; Antipsychotic Agents; Carbon Monoxide; Double-Blind Method; Female; Hum

2016
Lack of beneficial galantamine effect for smoking behavior: a double-blind randomized trial in people with schizophrenia.
    Schizophrenia research, 2008, Volume: 103, Issue:1-3

    Topics: Adult; alpha7 Nicotinic Acetylcholine Receptor; Antipsychotic Agents; Breath Tests; Carbon Monoxide;

2008
Smoking history and motivation to quit in smokers with schizophrenia in a smoking cessation program.
    Schizophrenia research, 2011, Volume: 126, Issue:1-3

    Topics: Adult; Carbon Monoxide; Double-Blind Method; Female; Humans; Male; Middle Aged; Motivation; Psychiat

2011
Effects of contingency management and bupropion on cigarette smoking in smokers with schizophrenia.
    Psychopharmacology, 2011, Volume: 217, Issue:2

    Topics: Adult; Behavior Therapy; Behavior, Addictive; Breath Tests; Bupropion; Carbon Monoxide; Combined Mod

2011
Rapid smoking may not be aversive in schizophrenia.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2013, Volume: 15, Issue:1

    Topics: Adult; Carbon Monoxide; Cotinine; Female; Humans; Male; Middle Aged; Schizophrenia; Schizophrenic Ps

2013
Impact of an electronic cigarette on smoking reduction and cessation in schizophrenic smokers: a prospective 12-month pilot study.
    International journal of environmental research and public health, 2013, Jan-28, Volume: 10, Issue:2

    Topics: Adult; Carbon Monoxide; Female; Humans; Male; Middle Aged; Prospective Studies; Schizophrenia; Smoki

2013
Contingent monetary reinforcement of smoking reductions, with and without transdermal nicotine, in outpatients with schizophrenia.
    Experimental and clinical psychopharmacology, 2002, Volume: 10, Issue:3

    Topics: Administration, Cutaneous; Adult; Breath Tests; Carbon Monoxide; Cotinine; Female; Humans; Male; Mot

2002
The effectiveness of nicotine-patch therapy for smoking cessation in patients with schizophrenia.
    International journal of nursing studies, 2004, Volume: 41, Issue:3

    Topics: Administration, Cutaneous; Adult; Carbon Monoxide; Female; Ganglionic Stimulants; Humans; Longitudin

2004
Effects of nicotine nasal spray on cognitive function in schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:3

    Topics: Adult; Antipsychotic Agents; Attention; Blood Pressure; Carbon Monoxide; Cognition; Cotinine; Double

2006
A 12-week double-blind, placebo-controlled study of bupropion sr added to high-dose dual nicotine replacement therapy for smoking cessation or reduction in schizophrenia.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:4

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Carbon Monoxide; Delayed-Action Preparat

2007
A 12-week double-blind, placebo-controlled study of bupropion sr added to high-dose dual nicotine replacement therapy for smoking cessation or reduction in schizophrenia.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:4

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Carbon Monoxide; Delayed-Action Preparat

2007
A 12-week double-blind, placebo-controlled study of bupropion sr added to high-dose dual nicotine replacement therapy for smoking cessation or reduction in schizophrenia.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:4

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Carbon Monoxide; Delayed-Action Preparat

2007
A 12-week double-blind, placebo-controlled study of bupropion sr added to high-dose dual nicotine replacement therapy for smoking cessation or reduction in schizophrenia.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:4

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Carbon Monoxide; Delayed-Action Preparat

2007

Other Studies

7 other studies available for carbon monoxide and Schizophrenia

ArticleYear
"Readiness to Change" Predicts Efficacy of Reduction among Smokers with Severe Mental Illness.
    European addiction research, 2019, Volume: 25, Issue:5

    Topics: Adult; Bipolar Disorder; Carbon Monoxide; Female; Humans; Longitudinal Studies; Male; Middle Aged; M

2019
Schizophrenia symptoms relieved by CO-induced pallidal lesion: a case report.
    The Journal of neuropsychiatry and clinical neurosciences, 2013,Spring, Volume: 25, Issue:2

    Topics: Antipsychotic Agents; Carbon Monoxide; Female; Globus Pallidus; Humans; Magnetic Resonance Imaging;

2013
Effects of smoking abstinence, smoking cues and nicotine replacement in smokers with schizophrenia and controls.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2008, Volume: 10, Issue:6

    Topics: Administration, Cutaneous; Adult; Carbon Monoxide; Cues; Female; Humans; Male; Nicotine; Schizophren

2008
Counseling and exercise intervention for smoking reduction in patients with schizophrenia: a feasibility study.
    Archives of psychiatric nursing, 2013, Volume: 27, Issue:1

    Topics: Adult; Carbon Monoxide; Counseling; Exercise; Feasibility Studies; Female; Humans; Male; Middle Aged

2013
Air pollution from traffic and schizophrenia risk.
    Schizophrenia research, 2004, Jan-01, Volume: 66, Issue:1

    Topics: Adolescent; Adult; Air Pollutants; Air Pollution, Indoor; Benzene; Carbon Monoxide; Causality; Child

2004
Higher nicotine and carbon monoxide levels in menthol cigarette smokers with and without schizophrenia.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2007, Volume: 9, Issue:8

    Topics: Adult; Analysis of Variance; Carbon Monoxide; Cotinine; Female; Flavoring Agents; Humans; Male; Ment

2007
Haloperidol increases smoking in patients with schizophrenia.
    Psychopharmacology, 1995, Volume: 119, Issue:1

    Topics: Adult; Carbon Monoxide; Female; Haloperidol; Humans; Male; Middle Aged; Nicotine; Schizophrenia; Smo

1995